“…The use of vitamin C against different diseases has been controversially and emotionally discussed since Linus Pauling published his cancer studies. In vitro and animal studies showed promising results and explained the impact of vitamin C, particularly in cases with endothelial dysfunction. …”
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“…Working under the supervisor of William Lawrence Bragg at the University of Manchester and being under the direct personal and scientific influence by Linus Pauling, Dr. James Fargher Keggin some 85 years ago published a highly unique discovery—the structure of phosphotungstic acid (Nature 1933, 131, 908–909). …”
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“…Importantly, however, studying rare diseases has contributed enormously to our understanding of human biochemistry, cell and developmental biology, and physiology. For example, Linus Pauling and Vernon Ingram's discovery of a structural difference and amino acid variant in the beta‐globin protein, which causes monogenic hemoglobinopathies such as sickle cell disease or thalassemia, issued in the era of molecular medicine (Pauling et al, 1949). …”
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“…Ever since Linus Pauling published his studies, the effects of vitamin C have been surrounded by contradictory results. …”
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“…The concept of odd-electron σ–bond was first proposed by Linus Pauling. Species containing such a bond have been recognized as important intermediates encountered in many fields. …”
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“…In the late 1970′s, Linus Pauling and Ewan Cameron reported that vitamin C may have positive effects in cancer treatment, although deep mechanistic knowledge about this activity is still scarce. …”
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“…Linus Pauling, who was awarded the Nobel Prize in Chemistry, suggested that a high dose of vitamin C (l-ascorbic acid) might work as a prevention or treatment for the common cold. …”
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