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721“…Now, we can choose in vivo, ex vivo, or in vitro live imaging systems according to the research objective. …”
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722por Zhang, Zhi, Xu, Duo, Fang, Jianyang, Wang, Dai, Zeng, Jie, Liu, Xiaodong, Hong, Shouqiang, Xue, Yunxin, Zhang, Xianzhong, Zhao, Xilin“…Whether the spatial and temporal distribution of gut microbiota, as a whole, affects or correlates with health is unknown, largely due to the absence of tools for dynamically monitoring the overall gut microbiota landscape inside living subjects. Here, we describe a novel, noninvasive, live imaging method for gut microbiota using 2-deoxy-2-[(18)F]fluoro-d-sorbitol ((18)F-FDS), a compound that specifically labeled gut bacteria in mice and hamsters following oral administration. …”
Publicado 2021
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724por Hwang, Sun-Hong, Kim, Ga-Yeong, Myeong, Su-Hwan, Yun, Tai-Sic, Yoon, Seung-Min, Kim, Tai-Ho, Euom, Ieck-Chae“…Recently, the number of users and the demand for live-streaming services have increased. This has exponentially increased the traffic to such services, and live-streaming service platforms in Korea use a grid computing system that distributes traffic to users and reduces traffic loads. …”
Publicado 2022
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725
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726
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727“…Live attenuated viral vaccines (LAV) have saved millions of lives globally through their capacity to elicit strong, cross-reactive and enduring adaptive immune responses. …”
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728por Morgado-Palacin, LuciaEnlace del recurso
Publicado 2022
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729por Qin, Weihua, Steinek, Clemens, Kolobynina, Ksenia, Forné, Ignasi, Imhof, Axel, Cardoso, M Cristina, Leonhardt, Heinrich“…Here, we employ recombinant binding domains to probe the ubiquitination of proteins in living cells. We immobilize GFP-fused proteins of interest at a distinct cellular structure and detect their ubiquitination state with red fluorescent ubiquitin binders. …”
Publicado 2022
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730
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731
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732“…To demonstrate the practical use of the model in treatment design, model calculations are used to predict the dosing schedule required to maintain persistent silencing of target proteins with different half-lives in rapidly dividing or nondividing cells. The approach of bioluminescent imaging combined with mathematical modeling provides useful insights into siRNA function and may help expedite the translation of siRNA into clinically relevant therapeutics for disease treatment and management.…”
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733“…Numerous commercial organic fluorophores with excellent optical properties are precluded from live-cell superresolution imaging due to poor cell permeability. …”
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734“…The goal of this review is to assess the degree to which both low-dosage and high-dosage corticosteroids contribute to serious adverse events (SAEs) following live varicella vaccination and live zoster vaccination. …”
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735por Bender, Ryan, Dong, Xue, Harris, Jason, Caughey, Sarah, Berri, Nabih, Spector, JasonEnlace del recurso
Publicado 2021
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736por Gogoi, Mayuri, Chaloner, Jonathan, Qureshi, Irtiza, Wobi, Fatimah, Al-Oraibi, Amani, Wilson, Heather, Suleman, Mehrunisha, Nellums, Laura, Pareek, Manish“…OBJECTIVES: The coronavirus disease 2019 (COVID-2019) pandemic has had far-reaching consequences for people’s lives. In the UK, more than 23 million have been infected and nearly 185 000 have lost their lives. …”
Publicado 2023
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737“…The PatLongLivedTracking algorithm is used to reconstruct tracks of daughters of long-lived particles such as $K_S^0$ and $\Lambda$ in Run $\text {II}$ of the LHCb data taking period. …”
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739por Potter, Sophie, Duezel, Sandra, Demuth, Ilja, Gerstorf, Denis, Drewelies, Johanna“…Given the growing evidence that the pandemic negatively affects older adults’ health and well-being, this study investigated health sensitivity (emotional reactions to momentary health challenges) and its moderators (age, morbidity, perceived COVID-19 risks and worries) among older adults in their everyday lives during the second and third waves of the pandemic. …”
Publicado 2023
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740“…However, minimal attention has been afforded to the lived experiences of persons undergoing inpatient treatment for AN. …”
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