Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6

por Harding, Rachel J., Franzoni, Ivan, Mann, Mandeep K., Szewczyk, Magdalena M., Mirabi, Bijan, Ferreira de Freitas, Renato, Owens, Dominic D. G., Ackloo, Suzanne, Scheremetjew, Alexej, Juarez-Ornelas, Kevin A., Sanichar, Randy, Baker, Rachel J., Dank, Christian, Brown, Peter J., Barsyte-Lovejoy, Dalia, Santhakumar, Vijayaratnam, Schapira, Matthieu, Lautens, Mark, Arrowsmith, Cheryl H.
Publicado 2023

Subthreshold opioid use disorder prevention (STOP) trial: a cluster randomized clinical trial: study design and methods

por Liebschutz, Jane M., Subramaniam, Geetha A., Stone, Rebecca, Appleton, Noa, Gelberg, Lillian, Lovejoy, Travis I., Bunting, Amanda M., Cleland, Charles M., Lasser, Karen E., Beers, Donna, Abrams, Catherine, McCormack, Jennifer, Potter, Gail E., Case, Ashley, Revoredo, Leslie, Jelstrom, Eve M., Kline, Margaret M., Wu, Li-Tzy, McNeely, Jennifer
Publicado 2023

Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5

por Senisterra, Guillermo, Wu, Hong, Allali-Hassani, Abdellah, Wasney, Gregory A., Barsyte-Lovejoy, Dalia, Dombrovski, Ludmila, Dong, Aiping, Nguyen, Kong T., Smil, David, Bolshan, Yuri, Hajian, Taraneh, He, Hao, Seitova, Alma, Chau, Irene, Li, Fengling, Poda, Gennadiy, Couture, Jean-François, Brown, Peter J., Al-Awar, Rima, Schapira, Matthieu, Arrowsmith, Cheryl H., Vedadi, Masoud
Publicado 2012

Lymphocytic Choriomeningitis Virus in Employees and Mice at Multipremises Feeder-Rodent Operation, United States, 2012

por Knust, Barbara, Ströher, Ute, Edison, Laura, Albariño, César G., Lovejoy, Jodi, Armeanu, Emilian, House, Jennifer, Cory, Denise, Horton, Clayton, Fowler, Kathy L., Austin, Jessica, Poe, John, Humbaugh, Kraig E., Guerrero, Lisa, Campbell, Shelley, Gibbons, Aridth, Reed, Zachary, Cannon, Deborah, Manning, Craig, Petersen, Brett, Metcalf, Douglas, Marsh, Bret, Nichol, Stuart T., Rollin, Pierre E.
Publicado 2014

Development of a dual antigen lateral flow immunoassay for detecting Yersinia pestis

por Hau, Derrick, Wade, Brian, Lovejoy, Chris, Pandit, Sujata G., Reed, Dana E., DeMers, Haley L., Green, Heather R., Hannah, Emily E., McLarty, Megan E., Creek, Cameron J., Chokapirat, Chonnikarn, Arias-Umana, Jose, Cecchini, Garett F., Nualnoi, Teerapat, Gates-Hollingsworth, Marcellene A., Thorkildson, Peter N., Pflughoeft, Kathryn J., AuCoin, David P.
Publicado 2022

Integrated digital error suppression for improved detection of circulating tumor DNA

por Newman, Aaron M., Lovejoy, Alexander F., Klass, Daniel M., Kurtz, David M., Chabon, Jacob J., Scherer, Florian, Stehr, Henning, Liu, Chih Long, Bratman, Scott V., Say, Carmen, Zhou, Li, Carter, Justin N., West, Robert B., Sledge, George W., Shrager, Joseph B., Loo, Billy W., Neal, Joel W., Wakelee, Heather A., Diehn, Maximilian, Alizadeh, Ash A.
Publicado 2016

Addressing our planetary crisis: Consensus statement from the presenters and International Advisory Committee of the Regional Action on Climate Change (RACC) Symposium held in conj...

por Falk, Jim, Attig-Bahar, Faten, Colwell, Rita R., Behera, Swadhin K., El-Beltagy, Adel S., von Braun, Joachim, Dasgupta, Partha, Gleick, Peter H., Kaneko, Ryuichi, Kennel, Charles F., Koundouri, Phoebe, Lee, Yuan Tseh, Lovejoy, Thomas E., Luers, Amy, Murray, Cherry A., Lal, Rattan, Serageldin, Ismail, Sokona, Youba, Takeuchi, Kazuhiko, Taniguchi, Makoto, Watanabe, Chiho, Yasunari, Tetsuzo
Publicado 2021

Discovery and Characterization of a Highly Potent and Selective Aminopyrazoline-Based in Vivo Probe (BAY-598) for the Protein Lysine Methyltransferase SMYD2

por Eggert, Erik, Hillig, Roman C., Koehr, Silke, Stöckigt, Detlef, Weiske, Jörg, Barak, Naomi, Mowat, Jeffrey, Brumby, Thomas, Christ, Clara D., ter Laak, Antonius, Lang, Tina, Fernandez-Montalvan, Amaury E., Badock, Volker, Weinmann, Hilmar, Hartung, Ingo V., Barsyte-Lovejoy, Dalia, Szewczyk, Magdalena, Kennedy, Steven, Li, Fengling, Vedadi, Masoud, Brown, Peter J., Santhakumar, Vijayaratnam, Arrowsmith, Cheryl H., Stellfeld, Timo, Stresemann, Carlo
Publicado 2016

TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma

por Nakayama, Kazuhide, Szewczyk, Magdalena M., dela Sena, Carlo, Wu, Hong, Dong, Aiping, Zeng, Hong, Li, Fengling, de Freitas, Renato Ferreira, Eram, Mohammad S., Schapira, Matthieu, Baba, Yuji, Kunitomo, Mihoko, Cary, Douglas R., Tawada, Michiko, Ohashi, Akihiro, Imaeda, Yasuhiro, Saikatendu, Kumar Singh, Grimshaw, Charles E., Vedadi, Masoud, Arrowsmith, Cheryl H., Barsyte-Lovejoy, Dalia, Kiba, Atsushi, Tomita, Daisuke, Brown, Peter J.
Publicado 2018

Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities

por Casey, Alison E., Sinha, Ankit, Singhania, Rajat, Livingstone, Julie, Waterhouse, Paul, Tharmapalan, Pirashaanthy, Cruickshank, Jennifer, Shehata, Mona, Drysdale, Erik, Fang, Hui, Kim, Hyeyeon, Isserlin, Ruth, Bailey, Swneke, Medina, Tiago, Deblois, Genevieve, Shiah, Yu-Jia, Barsyte-Lovejoy, Dalia, Hofer, Stefan, Bader, Gary, Lupien, Mathieu, Arrowsmith, Cheryl, Knapp, Stefan, De Carvalho, Daniel, Berman, Hal, Boutros, Paul C., Kislinger, Thomas, Khokha, Rama
Publicado 2018

Environmental vulnerability of the global ocean epipelagic plankton community interactome

por Chaffron, Samuel, Delage, Erwan, Budinich, Marko, Vintache, Damien, Henry, Nicolas, Nef, Charlotte, Ardyna, Mathieu, Zayed, Ahmed A., Junger, Pedro C., Galand, Pierre E., Lovejoy, Connie, Murray, Alison E., Sarmento, Hugo, Acinas, Silvia G., Babin, Marcel, Iudicone, Daniele, Jaillon, Olivier, Karsenti, Eric, Wincker, Patrick, Karp-Boss, Lee, Sullivan, Matthew B., Bowler, Chris, de Vargas, Colomban, Eveillard, Damien
Publicado 2021

Creating an Earth Archive

por Fisher, Christopher, Leisz, Stephen, Evans, Damian, Wall, Diana H., Galvin, Kathleen, Laituri, Melinda, Henebry, Geoffrey, Zeidler, James, Fernandez-Diaz, Juan Carlos, Pallickara, Shrideep, Pallickara, Sangmi, Garrison, Thomas, Estrada-Belli, Francisco, Neves, Eduardo, Reese-Taylor, Kathryn, Opitz, Rachel, Lovejoy, Thomas, Sarni, William, Solinis, Rodrigo, Ellis, Grace, Carvalho, Milena, White, Cheryl, Daggars, Louisa, Gasson-Pacheco, Rafael Angel, Bolaños, Aldo, Scarborough, Vern
Publicado 2022

Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway

por Lovejoy, Courtney A., Li, Wendi, Reisenweber, Steven, Thongthip, Supawat, Bruno, Joanne, de Lange, Titia, De, Saurav, Petrini, John H. J., Sung, Patricia A., Jasin, Maria, Rosenbluh, Joseph, Zwang, Yaara, Weir, Barbara A., Hatton, Charlie, Ivanova, Elena, Macconaill, Laura, Hanna, Megan, Hahn, William C., Lue, Neal F., Reddel, Roger R., Jiao, Yuchen, Kinzler, Kenneth, Vogelstein, Bert, Papadopoulos, Nickolas, Meeker, Alan K.
Publicado 2012

Discovery of a chemical probe for the L3MBTL3 methyl-lysine reader domain

por James, Lindsey I., Barsyte-Lovejoy, Dalia, Zhong, Nan, Krichevsky, Liubov, Korboukh, Victoria K., Herold, Martin J., MacNevin, Christopher J., Norris, Jacqueline L., Sagum, Cari A., Tempel, Wolfram, Marcon, Edyta, Guo, Hongbo, Gao, Cen, Huang, Xi-Ping, Duan, Shili, Emili, Andrew, Greenblatt, Jack F., Kireev, Dmitri B., Jin, Jian, Janzen, William P., Brown, Peter J., Bedford, Mark T., Arrowsmith, Cheryl H., Frye, Stephen V.
Publicado 2013

LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2

por Nguyen, Hannah, Allali-Hassani, Abdellah, Antonysamy, Stephen, Chang, Shawn, Chen, Lisa Hong, Curtis, Carmen, Emtage, Spencer, Fan, Li, Gheyi, Tarun, Li, Fengling, Liu, Shichong, Martin, Joseph R., Mendel, David, Olsen, Jonathan B., Pelletier, Laura, Shatseva, Tatiana, Wu, Song, Zhang, Feiyu Fred, Arrowsmith, Cheryl H., Brown, Peter J., Campbell, Robert M., Garcia, Benjamin A., Barsyte-Lovejoy, Dalia, Mader, Mary, Vedadi, Masoud
Publicado 2015

Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients

por Chabon, Jacob J., Simmons, Andrew D., Lovejoy, Alexander F., Esfahani, Mohammad S., Newman, Aaron M., Haringsma, Henry J., Kurtz, David M., Stehr, Henning, Scherer, Florian, Karlovich, Chris A., Harding, Thomas C., Durkin, Kathleen A., Otterson, Gregory A., Purcell, W. Thomas, Camidge, D. Ross, Goldman, Jonathan W., Sequist, Lecia V., Piotrowska, Zofia, Wakelee, Heather A., Neal, Joel W., Alizadeh, Ash A., Diehn, Maximilian
Publicado 2016

Corrigendum: Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients

por Chabon, Jacob J., Simmons, Andrew D., Lovejoy, Alexander F., Esfahani, Mohammad S., Newman, Aaron M., Haringsma, Henry J., Kurtz, David M., Stehr, Henning, Scherer, Florian, Karlovich, Chris A., Harding, Thomas C., Durkin, Kathleen A., Otterson, Gregory A., Thomas Purcell, W., Ross Camidge, D., Goldman, Jonathan W., Sequist, Lecia V., Piotrowska, Zofia, Wakelee, Heather A., Neal, Joel W., Alizadeh, Ash A., Diehn, Maximilian
Publicado 2016

Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3)

por Kaniskan, H. Ümit, Eram, Mohammad S., Zhao, Kehao, Szewczyk, Magdalena M., Yang, Xiaobao, Schmidt, Keith, Luo, Xiao, Xiao, Sean, Dai, Miao, He, Feng, Zang, Irene, Lin, Ying, Li, Fengling, Dobrovetsky, Elena, Smil, David, Min, Sun-Joon, Lin-Jones, Jennifer, Schapira, Matthieu, Atadja, Peter, Li, En, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Brown, Peter J., Liu, Feng, Yu, Zhengtian, Vedadi, Masoud, Jin, Jian
Publicado 2017

A chemical biology toolbox to study protein methyltransferases and epigenetic signaling

por Scheer, Sebastian, Ackloo, Suzanne, Medina, Tiago S., Schapira, Matthieu, Li, Fengling, Ward, Jennifer A., Lewis, Andrew M., Northrop, Jeffrey P., Richardson, Paul L., Kaniskan, H. Ümit, Shen, Yudao, Liu, Jing, Smil, David, McLeod, David, Zepeda-Velazquez, Carlos A., Luo, Minkui, Jin, Jian, Barsyte-Lovejoy, Dalia, Huber, Kilian V. M., De Carvalho, Daniel D., Vedadi, Masoud, Zaph, Colby, Brown, Peter J., Arrowsmith, Cheryl H.
Publicado 2019

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

por Grebien, Florian, Vedadi, Masoud, Getlik, Matthäus, Giambruno, Roberto, Grover, Amit, Avellino, Roberto, Skucha, Anna, Vittori, Sarah, Kuznetsova, Ekaterina, Smil, David, Barsyte-Lovejoy, Dalia, Li, Fengling, Poda, Gennadiy, Schapira, Matthieu, Wu, Hong, Dong, Aiping, Senisterra, Guillermo, Stukalov, Alexey, Huber, Kilian V. M., Schönegger, Andreas, Marcellus, Richard, Bilban, Martin, Bock, Christoph, Brown, Peter J., Zuber, Johannes, Bennett, Keiryn L., Al-awar, Rima, Delwel, Ruud, Nerlov, Claus, Arrowsmith, Cheryl H., Superti-Furga, Giulio
Publicado 2015