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201por Bergmann, Ralf, Meckel, Marian, Kubíček, Vojtěch, Pietzsch, Jens, Steinbach, Jörg, Hermann, Petr, Rösch, Frank“…The bone/blood ratios were between 3.6 and 135.6, correspondingly. (177)Lu-bisphosphonate dimers showed a slightly higher bone accumulation (SUV(femur) = 4.48 ± 0.38 for [(177)Lu]Lu-DO2A(P(BP))(2); SUV(femur) = 5.41 ± 0.46 for [(177)Lu]Lu-DOTA(M(BP))(2)) but a slower blood clearance (SUV(blood) = 1.25 ± 0.09 for [(177)Lu]Lu-DO2A(P(BP))(2); SUV(blood) = 1.43 ± 0.32 for [(177)Lu]Lu-DOTA(M(BP))(2)). …”
Publicado 2016
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202por Bailey, Dale L, Hennessy, Thomas M, Willowson, Kathy P, Henry, E Courtney, Chan, David LH, Aslani, Alireza, Roach, Paul J“…OBJECTIVE(S): Lutetium-177 can be made with high specific activity and with no other isotopes of lutetium present, referred to as “No Carrier Added” (NCA) (177)Lu. We have radiolabelled DOTA-conjugated peptide DOTA-(Tyr(3))-octreotate with NCA (177)Lu (“NCA-LuTATE”) and used it in nearly 40 therapeutic administrations for subjects with neuroendocrine tumours or meningiomas. …”
Publicado 2016
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203por Uribe, Carlos F., Esquinas, Pedro L., Tanguay, Jesse, Gonzalez, Marjorie, Gaudin, Emilie, Beauregard, Jean-Mathieu, Celler, Anna“…BACKGROUND: The aim of the study is to assess accuracy of activity quantification of (177)Lu studies performed according to recommendations provided by the committee on Medical Internal Radiation Dose (MIRD) pamphlets 23 and 26. …”
Publicado 2017
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204por Podleśny, Marcin, Kubik-Komar, Agnieszka, Kucharska, Jagoda, Wyrostek, Jakub, Jarocki, Piotr, Targoński, Zdzisław“…Enterobacter sp. LU1 could efficiently convert glycerol to succinic acid under anaerobic conditions after the addition of lactose. …”
Publicado 2017
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205por Sundlöv, Anna, Sjögreen-Gleisner, Katarina, Svensson, Johanna, Ljungberg, Michael, Olsson, Tomas, Bernhardt, Peter, Tennvall, Jan“…METHOD: Treatment was given with repeated cycles of 7.4 GBq (177)Lu-DOTATATE at 8-12-week intervals. Detailed dosimetry was performed in all patients after each cycle using a hybrid method (SPECT + planar imaging). …”
Publicado 2017
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206por Sundlöv, Anna, Gustafsson, Johan, Brolin, Gustav, Mortensen, Nadja, Hermann, Rebecca, Bernhardt, Peter, Svensson, Johanna, Ljungberg, Michael, Tennvall, Jan, Sjögreen Gleisner, Katarina“…BACKGROUND: Recently, (177)Lu-dotatate therapy for neuroendocrine tumours has received regulatory approval. …”
Publicado 2018
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207por Wevrett, Jill, Fenwick, Andrew, Scuffham, James, Johansson, Lena, Gear, Jonathan, Schlögl, Susanne, Segbers, Marcel, Sjögreen-Gleisner, Katarina, Solný, Pavel, Lassmann, Michael, Tipping, Jill, Nisbet, Andrew“…BACKGROUND: This inter-comparison exercise was performed to demonstrate the variability of quantitative SPECT/CT imaging for lutetium-177 ((177)Lu) in current clinical practice. Our aim was to assess the feasibility of using international inter-comparison exercises as a means to ensure consistency between clinical sites whilst enabling the sites to use their own choice of quantitative imaging protocols, specific to their systems. …”
Publicado 2018
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208Accuracy and reproducibility of simplified QSPECT dosimetry for personalized (177)Lu-octreotate PRRTpor Del Prete, Michela, Arsenault, Frédéric, Saighi, Nassim, Zhao, Wei, Buteau, François-Alexandre, Celler, Anna, Beauregard, Jean-Mathieu“…BACKGROUND: Routine dosimetry is essential for personalized (177)Lu-octreotate peptide receptor radionuclide therapy (PRRT) of neuroendocrine tumors (NETs), but practical and robust dosimetry methods are needed for wide clinical adoption. …”
Publicado 2018
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210por Hofving, Tobias, Sandblom, Viktor, Arvidsson, Yvonne, Shubbar, Emman, Altiparmak, Gülay, Swanpalmer, John, Almobarak, Bilal, Elf, Anna-Karin, Johanson, Viktor, Elias, Erik, Kristiansson, Erik, Forssell-Aronsson, Eva, Nilsson, Ola“…(177)Lu-octreotate is an FDA-approved radionuclide therapy for patients with gastroenteropancreatic neuroendocrine tumours (NETs) expressing somatostatin receptors. …”
Publicado 2019
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211por Fiorelli, Alfonso, D’Andrilli, Antonio, Carlucci, Annalisa, Vicidomini, Giovanni, Loizzi, Domenico, Ardò, Nicoletta Pia, Marasco, Rita Daniela, Ventura, Luigi, Ampollini, Luca, Carbognani, Paolo, Bocchialini, Giovanni, Lococo, Filippo, Paci, Massimiliano, Di Stefano, Teresa Severina, Ardissone, Francesco, Gagliasso, Matteo, Mendogni, Paolo, Rosso, Lorenzo, Mazzucco, Alessandra, Vanni, Camilla, Marinucci, Beatrice Trabalza, Potenza, Rossella, Matricardi, Alberto, Ragusa, Mark, Tassi, Valentina, Anile, Marco, Poggi, Camilla, Serra, Nicola, Sica, Antonello, Nosotti, Mario, Sollitto, Francesco, Venuta, Federico, Rendina, Erino Angelo, Puma, Francesco, Santini, Mario“…Herein, we evaluated the outcome and prognostic factors of Lung Cancer in Lymphoma Survivors (the LuCiLyS study) to improve the patient selection for lung cancer treatment. …”
Publicado 2020
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212“…The results have guiding significance for the synchronization unit design of LuTan-1 and the future BiSAR system.…”
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213por O’Neill, Edward, Kersemans, Veerle, Allen, P. Danny, Terry, Samantha Y.A., Torres, Julia Baguña, Mosley, Michael, Smart, Sean, Lee, Boon Quan, Falzone, Nadia, Vallis, Katherine A., Konijnenberg, Mark W., de Jong, Marion, Nonnekens, Julie, Cornelissen, Bart“…Molecular radiotherapy using (177)Lu-DOTATATE is a most effective treatment for somatostatin receptor–expressing neuroendocrine tumors. …”
Publicado 2020
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214“…Although complex Lü systems have been considered in many studies, application of the self-time-delay synchronization (STDS) of complex Lü systems in secure speech communications does not appear to have been covered in much of the literature. …”
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215por Uccelli, Licia, Boschi, Alessandra, Cittanti, Corrado, Martini, Petra, Panareo, Stefano, Tonini, Eugenia, Nieri, Alberto, Urso, Luca, Caracciolo, Matteo, Lodi, Luca, Carnevale, Aldo, Giganti, Melchiore, Bartolomei, Mirco“…In this review, covering twenty five years of literature, we describe the characteristics and performances of the two most used therapeutic radiopharmaceuticals for the NETs radio-treatment: [(90)Y]Y-DOTATOC and [(177)Lu]Lu-DOTATOC taking this opportunity to retrace the most significant results that have determined their success, promoting them from preclinical studies to application in humans.…”
Publicado 2021
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217por Lee, Hyobin, Lee, Keon Hee, Park, Jeong Sun, Lee, Gwan-Seok, Kim, Iksoo, Lee, Wonhoon“…Ricania shantungensis Chou & Lu, 1977 (Hemiptera: Ricaniidae), is an invasive pest that attacks forest as well as agricultural trees. …”
Publicado 2021
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218por Strosberg, Jonathan R., Srirajaskanthan, Rajaventhan, El-Haddad, Ghassan, Wolin, Edward M., Chasen, Beth A., Kulke, Matthew H., Bushnell, David L., Caplin, Martyn E., Baum, Richard P., Hendifar, Andrew E., Öberg, Kjell, Ruszniewski, Philippe, Santoro, Paola, Broberg, Per, Leeuwenkamp, Oscar R., Krenning, Eric P.“…We report the impact of (177)Lu-DOTATATE treatment on abdominal pain, diarrhea, and flushing, symptoms that patients with advanced midgut neuroendocrine tumors often find burdensome. …”
Publicado 2021
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219por Lundsten, Sara, Berglund, Hanna, Jha, Preeti, Krona, Cecilia, Hariri, Mehran, Nelander, Sven, Lane, David P., Nestor, Marika“…IMR-32 and PDX lines LU-NB-1 and LU-NB-2 were then cultured as multicellular tumor spheroids and treated with (177)Lu-DOTATATE and/or VIP116. …”
Publicado 2021
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220por Surekcigil Pesch, Isin, Bestelink, Eva, de Sagazan, Olivier, Mehonic, Adnan, Sporea, Radu A.“…Using MATLAB, we evaluate CNN performance using systematically distorted ReLU functions, then substitute measured and simulated MMT transfer characteristics as proxies for ReLU. …”
Publicado 2022
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