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101“…Here we show that increasing cholesterol levels are associated with peripheral monocyte depletion and this imbalance is aggravated by carriage of Lu/BCAM leukocyte adhesion molecules. This is true only in HIV infection and probably explains the risk of atherosclerosis observed in HIV-positive patients.…”
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102Publicado 2021“…Manh Tin Ho and Jiongming Lu are co-first authors on ‘A translation-independent activity of PheRS activates growth and proliferation in Drosophila’, published in DMM. …”
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103por Keam, Susan J.“…Lutetium Lu 177 vipivotide tetraxetan (PLUVICTO™, formerly known as (177)Lu-PSMA-617) is a radioligand therapeutic agent that is being developed by Advanced Accelerator Applications (a subsidiary of Novartis) for the treatment of prostate-specific membrane antigen (PSMA)-expressing metastatic prostate cancer. …”
Publicado 2022
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104por Dey, W, Aas, B, Ebersold, P, Engfer, R, Leisi, H J, Scheck, F, Schröder, W U, Walter, H K“…From an experiment performed at the muon-channel of the CERN Synchrocyclotron with a parasitic beam, the authors have observed the quadrupole splitting of the 4f-3d X-ray transition in muonic /sup 175/Lu. A preliminary evaluation of the data gives a nuclear spectroscopic quadrupole moment of the ground state of /sup 175/Lu, Q=3.46+or-0.06 b. …”
Publicado 1972
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105por Alipour, R., Jackson, P., Bressel, M., Hogg, A., Callahan, J., Hicks, R. J., Kong, G.“…METHODS: Patients with gastro-entero-pancreatic (GEP) NEN who received LuTate followed by quantitative SPECT/CT (Q-SPECT/CT) the next day (Jul 2010 to Jan 2019) were retrospectively reviewed. …”
Publicado 2023
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106por Gubbi, Sriram, Al-Jundi, Mohammad, Auh, Sungyoung, Jha, Abhishek, Zou, Joy, Shamis, Inna, Meuter, Leah, Knue, Marianne, Turkbey, Baris, Lindenberg, Liza, Mena, Esther, Carrasquillo, Jorge A., Teng, Yating, Pacak, Karel, Klubo-Gwiezdzinska, Joanna, Del Rivero, Jaydira, Lin, Frank I.“…PURPOSE: While there are reports of treatment-related endocrine disruptions and catecholamine surges in pheochromocytoma/paraganglioma (PPGL) patients treated with [(177)Lu]Lu-DOTA-TATE therapy, the spectrum of these abnormalities in the immediate post-treatment period (within 48 hours) has not been previously evaluated and is likely underestimated. …”
Publicado 2023
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107por Wild, Damian, Grønbæk, Henning, Navalkissoor, Shaunak, Haug, Alexander, Nicolas, Guillaume P., Pais, Ben, Ansquer, Catherine, Beauregard, Jean-Mathieu, McEwan, Alexander, Lassmann, Michael, Pennestri, Daniele, Volteau, Magali, Lenzo, Nat P., Hicks, Rodney J.“…PURPOSE: We present the results of an open-label, phase I/II study evaluating the safety and efficacy of the novel somatostatin receptor (SSTR) antagonist [(177)Lu]Lu-satoreotide tetraxetan in 40 patients with previously treated, progressive neuroendocrine tumours (NETs), in which dosimetry was used to guide maximum administered activity. …”
Publicado 2023
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108por Grzmil, Michal, Imobersteg, Stefan, Blanc, Alain, Frank, Stephan, Schibli, Roger, Béhé, Martin P.“…Both RAD001 and [(177)Lu]Lu-PP-F11N single treatments as well as their combination inhibited tumor growth and increased survival. …”
Publicado 2021
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109por Zisser, Lucia, Yu, Josef, Oszwald, André, Wollenweber, Tim, Kretschmer-Chott, Elisabeth, Grubmüller, Bernhard, Kramer, Gero, Shariat, Shahrokh F., Mitterhauser, Markus, Vraka, Chrysoula, Hacker, Marcus, Haug, Alexander R., Rasul, Sazan“…[(177)Lu]Lu-PSMA radioligand therapy (PSMA-RLT) is a promising therapy for patients with metastatic castration-resistant prostate cancer (mCRPC) and offers a survival benefit particularly to patients with only lymph node metastases. …”
Publicado 2022
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110por Ruigrok, Eline A. M., Verhoeven, Marjolein, Konijnenberg, Mark W., de Blois, Erik, de Ridder, Corrina M. A., Stuurman, Debra C., Bertarione, Luisa, Rolfo, Katia, de Jong, Marion, Dalm, Simone U.“…METHODS: Animals received either 3 injections, with a 7-day interval, of vehicle (control group 1), 1200 pmol [(175)Lu]Lu-NeoB (control group 2) or 40 MBq/400 pmol, 80 MBq/800 pmol, and 120 MBq/1200 pmol [(177)Lu]Lu-NeoB (treatment groups 1, 2, and 3, respectively). …”
Publicado 2022
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111por Hooijman, Eline L., Ntihabose, Carolline M., Reuvers, Thom G. A., Nonnekens, Julie, Aalbersberg, Else A., van de Merbel, Jordy R. J. P., Huijmans, Judith E., Koolen, Stijn L. W., Hendrikx, Jeroen J. M. A., de Blois, Erik“…Here we have proven that radiolysed [(177)Lu]Lu-PSMA has less binding affinity and thus likely will influence treatment efficacy. …”
Publicado 2022
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113por Liu, Shuping, Mares, Jiri A, Babin, Vladimir, Hu, Chen, Kou, Huamin, D’Ambrosio, Carmelo, Pan, Yubai, Nikl, Martin“…$Lu_{3}−_{x}Al_5O_{12}$:Ce optical ceramics ($Lu_3−_{x}AG:Ce,$ x = 1, 2, 3 and 4 at.%, respectively) with $Lu^{3+}$ compositions ranging from 1 to 4 at.% below stoichiometry content were fabricated by solid state reaction method and further optimized by an air-annealing process. …”
Publicado 2017
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114por Groener, Daniel, Wichert, Jennifer, Adams, Magdalena, Mader, Nicolai, Klimek, Konrad, Nguyen Ngoc, Christina, Baumgarten, Justus, Happel, Christian, Mandel, Philipp, Chun, Felix K. H., Tselis, Nikolaos, Grünwald, Frank, Sabet, Amir“…The presented study aims to assess the change in uptake to reference organs, including the liver, parotid and salivary glands after radioligand therapy (RLT) with [(177)Lu]Lu-PSMA-617 in relation to pretreatment imaging metrics. …”
Publicado 2023
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115por Silva, Maria Manuel, Canha, Marta, Salazar, Daniela, Neves, João Sergio, Ferreira, Gonçalo, Carvalho, Davide, Duarte, Hugo“…Our aim was to evaluate the efficacy and safety of a repeat (177)Lutetium-[DOTA°,Tyr(3)]octreotate ([(177)Lu]Lu-DOTA-TATE) PRRT course in patients with progressive NET after the first [(177)Lu]Lu-DOTA-TATE PRRT (peptide receptor radionuclide therapy first treatment (PRRT1)). …”
Publicado 2023
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116“…Lu(3+)/Yb(3+) and Lu(3+)/Er(3+) co-doped Sb(2)Se(3) nanomaterials were synthesized by co-reduction method in hydrothermal condition. …”
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117“…Li(2)SO(4) or (Li(2)SO(4) + SiO(2))-mixture fluxes were used to prepare a Lu(2)O(3):Eu powder phosphor as well as an undoped Lu(2)O(3) utilizing commercial lutetia and europia as starting reagents. …”
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118por Fan, Shiyu, Das, Hena, Rébola, Alejandro, Smith, Kevin A., Mundy, Julia, Brooks, Charles, Holtz, Megan E., Muller, David A., Fennie, Craig J., Ramesh, Ramamoorthy, Schlom, Darrell G., McGill, Stephen, Musfeldt, Janice L.“…Interface materials offer a means to achieve electrical control of ferrimagnetism at room temperature as was recently demonstrated in (LuFeO(3))(m)/(LuFe(2)O(4))(1) superlattices. A challenge to understanding the inner workings of these complex magnetoelectric multiferroics is the multitude of distinct Fe centres and their associated environments. …”
Publicado 2020
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119por Ruhwedel, Tristan, Rogasch, Julian M. M., Huang, Kai, Jann, Henning, Schatka, Imke, Furth, Christian, Amthauer, Holger, Wetz, Christoph“…Methods: Unicentric, retrospective analysis of 125 patients with NET undergoing PRRT with [(177)Lu]Lu-DOTATOC (female: 37%; median age: 66 years; G1+G2 NET: 95%). …”
Publicado 2021
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120por Wichmann, Christian W., Ackermann, Uwe, Poniger, Stan, Young, Kenneth, Nguyen, Benjamin, Chan, Gordon, Sachinidis, John, Scott, Andrew M.“…To facilitate clinical trials, fully automated procedures for the radiosyntheses of [(68)Ga]Ga‐PSMA‐11 and [(177)Lu]Lu‐PSMA‐617 were developed from commercially available precursors using the cassette based iPHASE MultiSyn module. …”
Publicado 2020
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