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  1. 459781
    “…Hospitalized and critical care patients showed lower HDL c blood levels and increased Tg/HDL c ratio than those with outpatient management and mild/asymptomatic COVID-19. Tg/HDL c ratio correlated with variables of disease severity such as lactate dehydrogenase (LDH) levels (r = 0.356; p < 0.05); National Early Warning Score 2 (NEWS 2) (r = 0.495; p < 0.01); quick sequential organ failure assessment (qSOFA) (r = 0.538; p < 0.001); increased need of oxygen support (r = 0.447; p < 0.01) and requirement of mechanical ventilation (r = 0.378; p < 0.05). …”
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    High triglyceride to HDL-cholesterol ratio as a biochemical marker of severe outcomes in COVID-19 patients
  2. 459782
    “…Organizations seeking to reduce physician stress may consider system-based changes to reduce EHR window switching or inbox work duration or the incorporation of inbox management time into work hours.…”
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    Physician Stress During Electronic Health Record Inbox Work: In Situ Measurement With Wearable Sensors
  3. 459783
    “…Gene expression analysis has been performed on clinical tumours but to date none of the gene expression-based biomarkers for prostate cancer have been successfully integrated to into clinical practice to improve patient management and treatment choice. We applied a novel laboratory prostate cancer model to mimic clinical hormone responsive and resistant prostate cancer and tested whether a network of genes similarly regulated by transcription factors (gene products that control the expression of target genes) are associated with patient outcome. …”
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    Gene Regulation Network Analysis on Human Prostate Orthografts Highlights a Potential Role for the JMJD6 Regulon in Clinical Prostate Cancer
  4. 459784
    por Ma, Qi, Sun, Chang‐jiao, Wu, Sha, Cai, Xu
    Publicado 2021
    “…At last 243 patients were enrolled, among which 88 patients were classified into the unilateral closed‐box group, 66 patients into the unilateral open‐box group, 47 patients into the one‐stage bilateral closed‐box group, and 42 patients into the one‐stage bilateral open‐box group. The perioperative management and operative techniques were almost the same for each patient, except the selection of prosthesis, which was decided according to surgeon's preference. …”
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    Comparison of Blood Loss between Open‐Box Prosthesis and Closed‐Box Prosthesis after Primary Total Knee Arthroplasty
  5. 459785
    “…Five patients required hospitalization for HHS or DKA and 1 patient was managed as an outpatient. Median random serum glucose on presentation was 761.5 mg/dl and median HbA1C on presentation was 11.5%. …”
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    Covid-19 and New Onset Diabetes: A Case Series
  6. 459786
    “…Increased attention towards management of serious non-covid-19 medical conditions is warranted.…”
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    Hospital admission and mortality rates for non-covid diseases in Denmark during covid-19 pandemic: nationwide population based cohort study
  7. 459787
    por Zhong, Qiuxia, Liu, Zhihua
    Publicado 2021
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    Efficacy and Safety of Anlotinib in Patients with Advanced Non-Small Cell Lung Cancer: A Real-World Study
  8. 459788
    “…SIMPLE SUMMARY: The introduction of BRAF/MEK-directed targeted therapy (TT) has significantly improved the management of patients with advanced BRAF-V600-mutant melanoma. …”
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    Discontinuation of BRAF/MEK-Directed Targeted Therapy after Complete Remission of Metastatic Melanoma—A Retrospective Multicenter ADOReg Study
  9. 459789
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    Survival Time to Development of Hypertension and Its Predictors among a Cohort of Diabetic Patients in Health Facilities of Gurage Zone: A Retrospective Follow-Up Study
  10. 459790
    “…We evaluated an online-based treatment designed to address stress, depression, and conflict management, the Dartmouth PATH Program, in a freely available and self-guided format during the COVID-19 pandemic. …”
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    Use of a Self-guided Computerized Cognitive Behavioral Tool During COVID-19: Evaluation Study
  11. 459791
    “…Results from this study, offers the opportunity to develop future therapeutic strategies for male fertility management, especially in pre-pubertal boys.…”
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    Effect of EPA on Neonatal Pig Sertoli Cells “In Vitro”: A Possible Treatment to Help Maintain Fertility in Pre-Pubertal Boys Undergoing Treatment With Gonado-Toxic Therapies
  12. 459792
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    The Diagnostic Value of Plasma miRNA-497, cTnI, FABP3 and GPBB in Pediatric Sepsis Complicated with Myocardial Injury
  13. 459793
    “…Health care practitioners could consider the potential need for close observation and cautious clinical management of children with these conditions and COVID-19.…”
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    Underlying Medical Conditions Associated With Severe COVID-19 Illness Among Children
  14. 459794
    “…These findings support pyronaridine–artesunate as an operationally useful addition to the management of acute uncomplicated malaria. TRIAL REGISTRATION: ClinicalTrials.gov NCT03201770.…”
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    Pyronaridine–artesunate real-world safety, tolerability, and effectiveness in malaria patients in 5 African countries: A single-arm, open-label, cohort event monitoring study
  15. 459795
    “…The results of the longitudinal analysis suggest that hearing impairment may be associated with poorer physical function with aging. Whether management of hearing impairment could delay decline in physical function requires further investigation.…”
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    Association of Age-Related Hearing Impairment With Physical Functioning Among Community-Dwelling Older Adults in the US
  16. 459796
    “…Referral to PC for both transfer of care and symptom management was associated with earlier PC consultation, p=0.021. …”
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    The Magnitude and Effects of Early Integration of Palliative Care Into Oncology Service Among Adult Advanced Cancer Patients at a Tertiary Care Hospital
  17. 459797
    “…CONCLUSIONS: We will develop the first web platform for people with NF with difficulties managing stress and NF symptoms and report on feasibility and preliminary effects in improving QoL and psychosocial functioning. …”
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    Adaptation of a Live Video Mind–Body Program to a Web-Based Platform for English-Speaking Adults With Neurofibromatosis: Protocol for the NF-Web Study
  18. 459798
    “…Introduction: Setmelanotide is a melanocortin 4 receptor agonist indicated for chronic weight management in patients with obesity due to proopiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1 (PCSK1), or leptin receptor (LEPR) deficiency. …”
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    Timing of Onset of Adverse Events With Setmelanotide, an MC4R Agonist, in Patients With Severe Obesity Due to LEPR or POMC Deficiency
  19. 459799
    “…This case uniquely spans eight years and therefore offers valuable insight into the appropriate work-up, management and long-term natural history of low fT4 in persons with HIV.…”
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    Discordant Thyroid Function Tests in Patients With HIV: A Case Report and Discussion of Diagnostic Approach
  20. 459800
    “…Our results support synergistic co-morbidity of ENDO and T1DM, which while currently underdiagnosed, may have significant implications in ENDO disease management.…”
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    Co-Morbidity of Type 1 Diabetes Promotes Endometriosis Status-A Pilot Study
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