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  1. 459861
    “…Overall glucose utilization was low, but regional increases were associated with reductions in glucose availability, blood flow and oxygen metabolism in the absence of ischaemia. Clinical management should optimize blood flow and glucose delivery and could explore the use of alternative energy substrates.…”
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    Metabolic derangements are associated with impaired glucose delivery following traumatic brain injury
  2. 459862
    “…Apatinib showed significant clinical benefits in both prolonged PFS and overall survival with a manageable safety profile in patients with progressive locally advanced or metastatic RAIR-DTC. …”
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    Apatinib vs Placebo in Patients With Locally Advanced or Metastatic, Radioactive Iodine–Refractory Differentiated Thyroid Cancer: The REALITY Randomized Clinical Trial
  3. 459863
    “…These findings suggest that prompt identification may improve the management of serious complications.…”
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    Factors Associated With Severe Gastrointestinal Diagnoses in Children With SARS-CoV-2 Infection or Multisystem Inflammatory Syndrome
  4. 459864
    “…As we have observed a shift towards more conservative, cost-conscious approaches to management, this study sought to compare short-term (30-day) perioperative and postoperative outcomes (complications and reoperations) in clubfoot patients who underwent either percutaneous Achilles tenotomy (PT) or combined open Achilles tenotomy with posterior capsulotomy (COTC). …”
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    Does Percutaneous Achilles Tenotomy Yield Comparable Short-Term Outcomes to Combined Open Achilles Tenotomy with Posterior Capsulotomy in Pediatric Patients with Clubfoot?
  5. 459865
    “…Within a total operative time of 190 minutes, three uni-malleolar ankle fractures and two bi-malleolar ankle fractures could be managed completely with an associated earning of $1,074 and $840 respectively. …”
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    Are Orthopaedic Surgeons Being Adequately Compensated for Ankle Fractures? An Analysis of Relative Value Units (RVUs)
  6. 459866
    “…These results may help guide appropriate management of expectations both pre and postoperatively. …”
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    Fulfillment of Patient Expectations at Two Years After Elective Foot and Ankle Surgery
  7. 459867
    “…CATEGORY: Bunion INTRODUCTION/PURPOSE: Postoperative pain management following orthopaedic surgeries is challenging, and the opioid epidemic has made it essential to better individualize opioid prescriptions by patient and procedure. …”
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    Comparison of Postoperative Opioid Consumption Following Hallux Valgus Correction Procedures
  8. 459868
    “…CATEGORY: Ankle, Ankle Arthritis INTRODUCTION/PURPOSE: The optimal management of severe ankle arthritis is still debated. …”
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    Intermediate to Long Term Follow Up of Hintegra Total Ankle Replacements
  9. 459869
    “…CATEGORY: Sports INTRODUCTION/PURPOSE: Osteochondral lesions of the talus (OLT) are common injuries, however management remains challenging. Lesion size remains a common determinant of treatment and microfracture remains common for smaller lesions. …”
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    Pain Scores and Return to Activities/Sport Following Dehydrated Micronized Allogenic Cartilage and Isolated Microfracture for Treatment of Talar Osteochondral Lesions
  10. 459870
    “…CATEGORY: Ankle; Ankle Arthritis; Bunion; Hindfoot; Midfoot/Forefoot; Other INTRODUCTION/PURPOSE: The analysis of the hindfoot alignment (HA) is important in the management of various foot and ankle pathologies. Foot Ankle Offset (FAO), measured using Weight Bearing CT (WBCT) scans is a 3D biometric measurement of HA described in the literature, however only with relation to the clinical morphology of the hindfoot or previously known 2D biometrics such as the hindfoot angle. …”
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    Redefining Hindfoot Alignment Based on Pathology rather than Morphology: A Prospective Observational Diagnostic Study on 250 Feet
  11. 459871
    “…Identifying fractures preoperatively that are likely to have syndesmotic injury is beneficial to surgeon and patient as it aids in operative planning, intraoperative equipment needs, managing patient expectations, and counselling patients preoperatively about changes in rehabilitation protocols with injuries that involve the syndesmosis. …”
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    Syndesmosis Injuries in Ankle Fractures: Correlation of Fracture Type and Syndesmotic Instability
  12. 459872
    “…The assessment of NT‐proBNP dynamics may be valuable to assess the residual risk for patients undergoing TMVR and could assist with post‐procedural management after TMVR.…”
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    Periprocedural changes in natriuretic peptide levels and clinical outcome after transcatheter mitral valve repair
  13. 459873
    “…BACKGROUND: Sharing data from wearable health and activity trackers (wearables) with others may improve the health and behavioral outcomes of wearable users by generating social support and improving their ability to manage their health. Investigating individual factors that influence US adults’ willingness to share wearable data with different types of individuals may provide insights about the population subgroups that are most or least likely to benefit from wearable interventions. …”
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    Willingness to Share Data From Wearable Health and Activity Trackers: Analysis of the 2019 Health Information National Trends Survey Data
  14. 459874
    “…Colorectal cancer (CRC) is one of the most common cancer worldwide, with a growing impact on public health and clinical management. Immunotherapy has shown promise in the treatment of advanced cancers, but needs to be improved for CRC, since only a limited fraction of patients is eligible for treatment, and most of them develop resistance due to progressive immune exhaustion. …”
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    Colorectal Cancer-Associated Immune Exhaustion Involves T and B Lymphocytes and Conventional NK Cells and Correlates With a Shorter Overall Survival
  15. 459875
    “…There are currently no standardized approaches to the management of pancreatic cancer cachexia. This study explores the feasibility and efficacy of enteral tube feeding of a peptide‐based formula to improve weight stability and patient‐reported outcomes (PROs) in advanced PDAC patients with cachexia. …”
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    Feasibility and efficacy of enteral tube feeding on weight stability, lean body mass, and patient‐reported outcomes in pancreatic cancer cachexia
  16. 459876
    “…CATEGORY: Bunion; Midfoot/Forefoot INTRODUCTION/PURPOSE: The PROMIS self-efficacy of symptom management(SE)(psychological) and satisfaction with social roles (SR) (social) outcomes when combined with the physical function(PF) and pain interference (PI) (biologic) outcomes capture a patient’s biopsychosocial status. …”
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    Do PROMIS® Biopsychosocial Measures Inform Clinical Decisions in Patients with Hallux Valgus?
  17. 459877
    “…We sought to compare a novel biologic technique of Biocartilage and BMAC with microfracture for OCL management. Our results demonstrated no significant difference between treatments for postoperative PROMIS and MOCART scores. …”
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    Functional and Radiographic Outcomes Following Repair of Osteochondral Lesions After Ankle Fracture with Arthrex BioCartilage and Bone Marrow Aspirate Concentrate compared to Microfracture
  18. 459878
    “…Serious games (SGs) are a novel way to promote the safe and responsible management of opioid medications among adolescents, thereby reducing the number of adolescent opioid misuse cases reported annually. …”
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    Investigating the Use of a Serious Game to Improve Opioid Safety Awareness Among Adolescents: Quantitative Study
  19. 459879
    “…The trial included patients with a primary bone tumor or a soft tissue sarcoma that had invaded the femur or tibia or oligometastatic bone disease of the femur or tibia with expected survival of at least 1 year who required surgical management by excision and endoprosthetic reconstruction. …”
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    Comparison of Prophylactic Intravenous Antibiotic Regimens After Endoprosthetic Reconstruction for Lower Extremity Bone Tumors: A Randomized Clinical Trial
  20. 459880
    “…IMPORTANCE: Maximal resection is the preferred management for sacral chordomas but can be associated with unacceptable morbidity. …”
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    Comparison of Oncologic Outcomes and Treatment-Related Toxicity of Carbon Ion Radiotherapy and En Bloc Resection for Sacral Chordoma
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