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  1. 1361
    “…METHOD: Two case-control studies nested within a screening cohort (ages of participants 46–73 years) from Manchester UK were used. In the first study (317 cases and 947 controls) cases were detected at the first screen; whereas in the second study (318 cases and 935 controls), cases were diagnosed after the initial mammogram. …”
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    Exploring the prediction performance for breast cancer risk based on volumetric mammographic density at different thresholds
  2. 1362
    “…Children triaged green on the Manchester Triage System without any comorbidities were classed as ‘GP appropriate’. …”
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    To GP or not to GP: a natural experiment in children triaged to see a GP in a tertiary paediatric emergency department (ED)
  3. 1363
    “…METHODS: We conducted the study at The University of Manchester within a near-peer scheme aimed at developing clinical skills within clinical clerkship students. …”
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    “You understand that whole big situation they’re in”: interpretative phenomenological analysis of peer-assisted learning
  4. 1364
    “…ETHICS AND DISSEMINATION: The study received a favourable opinion by the Greater Manchester Central Research Ethics Committee, UK (17/NW/0012). …”
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    Low-dose interleukin-2 in patients with stable ischaemic heart disease and acute coronary syndromes (LILACS): protocol and study rationale for a randomised, double-blind, placebo-controlled, phase I/II clinical trial
  5. 1365
    “…The study was part of the European Medical Information Framework for AD (EMIF-AD) and was conducted at the Amsterdam University Medical Centers (UMC) and at the University of Manchester. We will test whether cognitive resilience is associated with cognitive reserve, vascular comorbidities, mood, sleep, sensory system capacity, physical performance and capacity, genetic risk factors, hallmarks of ageing, and markers of neurodegeneration. …”
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    Resilience to cognitive impairment in the oldest-old: design of the EMIF-AD 90+ study
  6. 1366
    “…RESULTS: We recruited 25 participants, 12 women (48%), ranging from ages 60 years to 85 years (M=69.12, SD=6.57), all from Greater Manchester. Participants came from varied socioeconomic backgrounds, with 22 identifying as Pakistani, one as British Pakistani and two as East African. …”
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    Cultural validation of the Addenbrooke’s Cognitive Examination Version III Urdu for the British Urdu-speaking population: a qualitative assessment using cognitive interviewing
  7. 1367
    “…The study has received ethical approval from North West Greater Manchester Research Ethics Committee (ref.: 18/NW/0079). …”
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    Investigating a therapist-guided, parent-assisted remote digital behavioural intervention for tics in children and adolescents—‘Online Remote Behavioural Intervention for Tics’ (ORBIT) trial: protocol of an internal pilot study and single-blind randomised controlled trial
  8. 1368
    “…Patients were triaged according to Local Triage System (LTS), and the information collected were used to assign acuities in the other triage scales: Canadian Triage and Acuity Scale (CTAS), Australasian Triage Scale (ATS), Manchester Triage Scale (MTS) and South African Triage Scale (SATS). …”
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    Performance characteristics of a local triage tool and internationally validated tools among under-fives presenting to an urban emergency department in Tanzania
  9. 1369
    “…METHODS AND ANALYSIS: In this retrospective case series, we included 40 eyes of 36 patients with nAMD with CNV assessed by OCTA at the Manchester Eye Hospital between June 2016 and June 2017. …”
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    Effect of total anti-VEGF treatment exposure on patterns of choroidal neovascularisation assessed by optical coherence tomography angiography in age-related macular degeneration: a retrospective case series
  10. 1370
    “…METHODS: We recruited patients with at least 1 SARD clinical feature and at least 1 SARD-related autoantibody from two NHS Trusts in Greater Manchester. A 6-gene interferon-stimulated gene (ISG) score was calculated in all patients, and in a subgroup, a 30-gene ISG score was produced using NanoString. …”
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    Type I interferon in patients with systemic autoimmune rheumatic disease is associated with haematological abnormalities and specific autoantibody profiles
  11. 1371
    “…Plantar heel pain in the last month was defined by self-reported shading on a foot manikin, and was defined as disabling if at least one of the function items of the Manchester Foot Pain and Disability Index were also reported. …”
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    Plantar heel pain in middle-aged and older adults: population prevalence, associations with health status and lifestyle factors, and frequency of healthcare use
  12. 1372
    “…Secondary outcome measures will include the Manchester-Oxford Foot Questionnaire (MOXFQ), EuroQol-5D (EQ-5D), pain, treatment satisfaction, time to return to activity, operative tourniquet time, and complications. …”
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    Medial malleolus: Operative Or Non-operative (MOON) trial protocol - a prospective randomised controlled trial of operative versus non-operative management of associated medial malleolus fractures in unstable fractures of the ankle
  13. 1373
    “…During follow-up the Manchester Scar Scores were lesser in the Pfannenstiel-incision group (P < 0.001). …”
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    Iliac fossa vs Pfannenstiel retrieval incision in laparoscopic donor nephrectomy: A critical analysis
  14. 1374
    “…DESIGN: Cross-sectional postal survey design applying the ‘7Ps marketing mix’ (‘product’, ‘price’, ‘place’, ‘promotion’, ‘people’, ‘process’ and ‘physical evidence’). SETTING: Greater Manchester, England. PARTICIPANTS: Patients with asthma or chronic obstructive pulmonary disease registered at two GP practices. …”
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    Applying a whole systems lens to the general practice crisis: cross-sectional survey looking at usage of community pharmacy services in England by patients with long-term respiratory conditions
  15. 1375
    “…BACKGROUND: Thousands of injured, stray and relinquished cats are received at the RSPCA Greater Manchester Animal Hospital each year. A significant and challenging proportion of these cats are confiscated from multicat households by RSPCA Inspectors, due to the owners’ inability to care for them. …”
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    A novel approach to welfare interventions in problem multi-cat households
  16. 1376
    “…We then tested the impact of the choice of the most common definitions of ‘cases’ and ‘controls’ on AD prevalence estimates and associated risk factors (including filaggrin mutations) among children aged 5 years in two population‐based birth cohorts: the Manchester Asthma and Allergy Study (MAAS) and Asthma in Ashford. …”
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    Different definitions of atopic dermatitis: impact on prevalence estimates and associated risk factors
  17. 1377
    “…ETHICS AND DISSEMINATION: This study has ethical approval from the Greater Manchester Central Research Ethics Committee (reference no. 18/NW/0031) and clinical trial authorisation from the Medicine and Healthcare Products Regulatory Agency. …”
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    NET-02 trial protocol: a multicentre, randomised, parallel group, open-label, phase II, single-stage selection trial of liposomal irinotecan (nal-IRI) and 5-fluorouracil (5-FU)/folinic acid or docetaxel as second-line therapy in patients with progressive poorly differentiated extrapulmonary neuroendocrine carcinoma (NEC)
  18. 1378
    “…METHODS: A total of 5925 individuals of European Ancestry were categorized into two groups: ‘hallux valgus present’ (n = 2314) or ‘no deformity’ (n = 3611) as determined by trained examiners or using the Manchester grading scale. Genotyping was performed using commercially available arrays followed by imputation to the Haplotype Reference Consortium (HRC) reference panel version 1.1. …”
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    Genome-wide meta-analysis identified novel variant associated with hallux valgus in Caucasians
  19. 1379
    “…One hundred and six participants, tested on a gene panel which contained both isolated and syndromic IRD genes, were retrospectively ascertained from the Manchester Genomic Diagnostics Laboratory database spanning 6 years (2012–2017). …”
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    Diagnostic yield of panel-based genetic testing in syndromic inherited retinal disease
  20. 1380
    por Portelli, Michael A., Dijk, F. Nicole, Ketelaar, Maria E., Shrine, Nick, Hankinson, Jenny, Bhaker, Sangita, Grotenboer, Néomi S., Obeidat, Ma’en, Henry, Amanda P., Billington, Charlotte K., Shaw, Dominick, Johnson, Simon R., Pogson, Zara E.K., Fogarty, Andrew, McKeever, Tricia M., Nickle, David C., Bossé, Yohan, van den Berge, Maarten, Faiz, Alen, Brouwer, Sharon, Vonk, Judith M., de Vos, Paul, Brandsma, Corry-Anke, Vermeulen, Cornelis J., Singapuri, Amisha, Heaney, Liam G., Mansur, Adel H., Chaudhuri, Rekha, Thomson, Neil C., Holloway, John W., Lockett, Gabrielle A., Howarth, Peter H., Niven, Robert, Simpson, Angela, Blakey, John D., Tobin, Martin D., Postma, Dirkje S., Hall, Ian P., Wain, Louise V., Nawijn, Martijn C., Brightling, Christopher E., Koppelman, Gerard H., Sayers, Ian
    Publicado 2020
    “…Utilizing 4 independent cohorts (Lifelines, Dutch Asthma GWAS [DAG], Genetics of Asthma Severity and Phenotypes [GASP], and Manchester Asthma and Allergy Study [MAAS]) and resequencing data, we identified 3 key signals associated with asthma features. …”
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    Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium
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