The Gut Hormones PYY(3-36) and GLP-1(7-36 amide) Reduce Food Intake and Modulate Brain Activity in Appetite Centers in Humans

por De Silva, Akila, Salem, Victoria, Long, Christopher J., Makwana, Aidan, Newbould, Rexford D., Rabiner, Eugenii A., Ghatei, Mohammad A., Bloom, Stephen R., Matthews, Paul M., Beaver, John D., Dhillo, Waljit S.
Publicado 2011

Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site

por Bolanos-Garcia, Victor M., Lischetti, Tiziana, Matak-Vinković, Dijana, Cota, Ernesto, Simpson, Pete J., Chirgadze, Dimitri Y., Spring, David R., Robinson, Carol V., Nilsson, Jakob, Blundell, Tom L.
Publicado 2011

Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824

por Cellitti, Susan E., Shaffer, Jennifer, Jones, David H., Mukherjee, Tathagata, Gurumurthy, Meera, Bursulaya, Badry, Boshoff, Helena I., Choi, Inhee, Nayyar, Amit, Lee, Yong Sok, Cherian, Joseph, Niyomrattanakit, Pornwaratt, Dick, Thomas, Manjunatha, Ujjini H., Barry, Clifton E., Spraggon, Glen, Geierstanger, Bernhard H.
Publicado 2012

Angiogenic Sprouting Requires the Fine Tuning of Endothelial Cell Cohesion by the Raf-1/Rok-α Complex

por Wimmer, Reiner, Cseh, Botond, Maier, Barbara, Scherrer, Karina, Baccarini, Manuela
Publicado 2012

The JAK/STAT Pathway Is Involved in Synaptic Plasticity

por Nicolas, Céline S., Peineau, Stéphane, Amici, Mascia, Csaba, Zsolt, Fafouri, Assia, Javalet, Charlotte, Collett, Valerie J., Hildebrandt, Lars, Seaton, Gillian, Choi, Sun-Lim, Sim, Su-Eon, Bradley, Clarrisa, Lee, Kyungmin, Zhuo, Min, Kaang, Bong-Kiun, Gressens, Pierre, Dournaud, Pascal, Fitzjohn, Stephen M., Bortolotto, Zuner A., Cho, Kwangwook, Collingridge, Graham L.
Publicado 2012

Kinetochore-Dependent Microtubule Rescue Ensures Their Efficient and Sustained Interactions in Early Mitosis

por Gandhi, Sapan R., Gierliński, Marek, Mino, Akihisa, Tanaka, Kozo, Kitamura, Etsushi, Clayton, Lesley, Tanaka, Tomoyuki U.
Publicado 2011

Plk1 and CK2 Act in Concert to Regulate Rad51 during DNA Double Strand Break Repair

por Yata, Keiko, Lloyd, Janette, Maslen, Sarah, Bleuyard, Jean-Yves, Skehel, Mark, Smerdon, Stephen J., Esashi, Fumiko
Publicado 2012

Structural Dynamics Associated with Intermediate Formation in an Archetypal Conformational Disease

por Nyon, Mun Peak, Segu, Lakshmi, Cabrita, Lisa D., Lévy, Géraldine R., Kirkpatrick, John, Roussel, Benoit D., Patschull, Anathe O.M., Barrett, Tracey E., Ekeowa, Ugo I., Kerr, Richard, Waudby, Christopher A., Kalsheker, Noor, Hill, Marian, Thalassinos, Konstantinos, Lomas, David A., Christodoulou, John, Gooptu, Bibek
Publicado 2012

Imprinted Gene Dosage Is Critical for the Transition to Independent Life

por Charalambous, Marika, Ferron, Sacramento R., da Rocha, Simao T., Murray, Andrew J., Rowland, Timothy, Ito, Mitsuteru, Schuster-Gossler, Karin, Hernandez, Arturo, Ferguson-Smith, Anne C.
Publicado 2012

Local Translation of Extranuclear Lamin B Promotes Axon Maintenance

por Yoon, Byung C., Jung, Hosung, Dwivedy, Asha, O'Hare, Catherine M., Zivraj, Krishna H., Holt, Christine E.
Publicado 2012

Opposing Functions of the ETS Factor Family Define Shh Spatial Expression in Limb Buds and Underlie Polydactyly

por Lettice, Laura A., Williamson, Iain, Wiltshire, John H., Peluso, Silvia, Devenney, Paul S., Hill, Alison E., Essafi, Abdelkader, Hagman, James, Mort, Richard, Grimes, Graeme, DeAngelis, Carlo L., Hill, Robert E.
Publicado 2012

Structure of orbitofrontal cortex predicts social influence

por Campbell-Meiklejohn, Daniel K., Kanai, Ryota, Bahrami, Bahador, Bach, Dominik R., Dolan, Raymond J., Roepstorff, Andreas, Frith, Chris D.
Publicado 2012

Structure of the Discoidin Domain Receptor 1 Extracellular Region Bound to an Inhibitory Fab Fragment Reveals Features Important for Signaling

por Carafoli, Federico, Mayer, Marie Cathrin, Shiraishi, Kazushige, Pecheva, Mira Anguelova, Chan, Lai Yi, Nan, Ruodan, Leitinger, Birgit, Hohenester, Erhard
Publicado 2012

ATP-Triggered Conformational Changes Delineate Substrate-Binding and -Folding Mechanics of the GroEL Chaperonin

por Clare, Daniel K., Vasishtan, Daven, Stagg, Scott, Quispe, Joel, Farr, George W., Topf, Maya, Horwich, Arthur L., Saibil, Helen R.
Publicado 2012

Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

por Filippakopoulos, Panagis, Picaud, Sarah, Mangos, Maria, Keates, Tracy, Lambert, Jean-Philippe, Barsyte-Lovejoy, Dalia, Felletar, Ildiko, Volkmer, Rudolf, Müller, Susanne, Pawson, Tony, Gingras, Anne-Claude, Arrowsmith, Cheryl H., Knapp, Stefan
Publicado 2012

Epiblast Stem Cell-Based System Reveals Reprogramming Synergy of Germline Factors

por Gillich, Astrid, Bao, Siqin, Grabole, Nils, Hayashi, Katsuhiko, Trotter, Matthew W.B., Pasque, Vincent, Magnúsdóttir, Erna, Surani, M. Azim
Publicado 2012

Long-Term Memory for Affiliates in Ravens

por Boeckle, Markus, Bugnyar, Thomas
Publicado 2012

Waves of Retrotransposon Expansion Remodel Genome Organization and CTCF Binding in Multiple Mammalian Lineages

por Schmidt, Dominic, Schwalie, Petra C., Wilson, Michael D., Ballester, Benoit, Gonçalves, Ângela, Kutter, Claudia, Brown, Gordon D., Marshall, Aileen, Flicek, Paul, Odom, Duncan T.
Publicado 2012

Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

por Cremades, Nunilo, Cohen, Samuel I.A., Deas, Emma, Abramov, Andrey Y., Chen, Allen Y., Orte, Angel, Sandal, Massimo, Clarke, Richard W., Dunne, Paul, Aprile, Francesco A., Bertoncini, Carlos W., Wood, Nicholas W., Knowles, Tuomas P.J., Dobson, Christopher M., Klenerman, David
Publicado 2012

Proneural Transcription Factors Regulate Different Steps of Cortical Neuron Migration through Rnd-Mediated Inhibition of RhoA Signaling

por Pacary, Emilie, Heng, Julian, Azzarelli, Roberta, Riou, Philippe, Castro, Diogo, Lebel-Potter, Mélanie, Parras, Carlos, Bell, Donald M., Ridley, Anne J., Parsons, Maddy, Guillemot, François
Publicado 2011