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Mostrando 181 - 200 Resultados de 1,360,514 Para Buscar '"M', tiempo de consulta: 2.65s Limitar resultados
  1. 181
    “…The mammalian target of rapamycin (mTOR) is a crucial signaling node that integrates environmental cues to regulate cell survival, proliferation, and metabolism, and is often deregulated in human cancer. mTOR kinase acts in two functionally distinct complexes, mTOR complex 1 (mTORC1) and 2 (mTORC2), whose activities and substrate specificities are regulated by complex co-factors. …”
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    mTORC1 and mTORC2 in cancer and the tumor microenvironment
  2. 182
    por Ryder, Sean P.
    Publicado 2016
    “…RNA-binding proteins play a variety of roles in cellular physiology. Some regulate mRNA processing, mRNA abundance, and translation efficiency. …”
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    Protein-mRNA interactome capture: cartography of the mRNP landscape
  3. 183
    Publicado 1845
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    Manual of Diseases of the Skin, from the French of M. M. Cazenave and Schedel
  4. 184
    Publicado 1895
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    Chapin A. Harris, A. M., M. D., D. D. S.
  5. 185
    “…N(6)-methyladenosine (m(6)A) is the most prevalent modified nucleotide in mRNA(1,2), with ~25% of mRNAs containing at least one m(6)A. …”
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    m(6)A enhances the phase separation potential of mRNA
  6. 186
    “…Ribonucleic acid (RNA) methylation is considered to be a major discovery following the deoxyribonucleic acid (DNA) and histone methylation. Messenger RNA (mRNA) methylation modification accounts for more than 60% of all RNA modifications and N6-methyladenosine (m(6)A) is known as one of the most common type of eukaryotic mRNA methylation modifications in current. …”
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    The role of mRNA m(6)A methylation in the nervous system
  7. 187
    “…METHODS: Using a whole-body 300 mT/m gradient MRI system, a cohort of participants was scanned with the head, heart, and prostate at magnet isocenter and a train of trapezoidal bipolar gradient pulses, with ramp times from 0.88 to 4.20 ms and gradient amplitudes from 60 to 300 mT/m. …”
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    Physiological effects of human body imaging with 300 mT/m gradients
  8. 188
    “…During malarial infection, Plasmodium parasites digest human hemoglobin to obtain free amino acids for protein production and maintenance of osmotic pressure. The Plasmodium M1 and M17 aminopeptidases are both postulated to have an essential role in the terminal stages of the hemoglobin digestion process and are validated drug targets for the design of new dual-target anti-malarial compounds. …”
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    Mapping the substrate specificity of the Plasmodium M1 and M17 aminopeptidases
  9. 189
    “…Collectively, we found that: (1) SMN coexists with nucleolin–mTOR mRNA complexes at subcellular level; (2) SMN deficiency impairs nucleolar compartmentalization of nucleolin, and (3) this event correlates with the nuclear retention of mTOR mRNA. …”
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    Fine-Tuning of mTOR mRNA and Nucleolin Complexes by SMN
  10. 190
    por Gaiotto, Davide, Rapčák, Miroslav
    Publicado 2022
    “…We determine the mathematical structures which govern the Ω deformation of supersymmetric intersections of M2 and M5 branes. We find that the supersymmetric intersections govern many aspects of the theory of W-algebras, including degenerate modules, the Miura transform and Coulomb gas constructions. …”
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    Miura operators, degenerate fields and the M2-M5 intersection
  11. 191
    “…N(6)-Methyladenosine (m6A), the most abundant internal modification associated with eukaryotic mRNAs, has emerged as a dynamic regulatory mechanism controlling the expression of genes involved in many physiological activities by affecting various steps of mRNA metabolism, including splicing, export, translation, and stability. …”
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    Dynamic regulation and functions of mRNA m6A modification
  12. 192
    por Guo, Shenrui, Wang, Hui, Yin, Yafu
    Publicado 2022
    “…Microglia can be categorized into two opposite types: classical (M1) or alternative (M2), though there’s a continuum of different intermediate phenotypes between M1 and M2, and microglia can transit from one phenotype to another. …”
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    Microglia Polarization From M1 to M2 in Neurodegenerative Diseases
  13. 193
    “…In this paper, we propose a novel model called Transformer in M-Net (TiM-Net) based on M-Net, diverse attention mechanisms, and weighted side output layers to efficaciously perform retinal vessel segmentation. …”
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    TiM-Net: Transformer in M-Net for Retinal Vessel Segmentation
  14. 194
    Publicado 1903
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    Samuel Hollingsworth Stout, A. M., M. D., LL. D.
  15. 195
    por Hayes, J. R.
    Publicado 1892
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    Nasal Polypi Cured with One Dose of Aurum-M,(50m)
  16. 196
    “…Group A Streptococcus (GAS) M and M-like proteins are essential virulence factors and represent the primary epidemiological marker of this pathogen. …”
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    Promiscuous evolution of Group A Streptococcal M and M-like proteins
  17. 197
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    Excitation of the high-spin isomers $^{180m}$Hf, $^{190m}$Os and $^{204m}$Pb in ($\gamma$,$\gamma$') reactions
  18. 198
    “…Herein, we report the synthesis and electrochemical properties of a new family of nitrogen-doped metal/carbon (M/N/C, M = Fe, Co, Ni) nanocomposites. The M/N/C nanocomposites, in which metal nanoparticles are embedded in the highly porous nitrogen-doped carbon matrix, have been synthesized by simply pyrolyzing M(salen) (salen = N,N′-bis(salicylidene)-ethylenediamine) complex precursors. …”
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    M(Salen)-derived Nitrogen-doped M/C (M = Fe, Co, Ni) Porous Nanocomposites for Electrocatalytic Oxygen Reduction
  19. 199
    “…Our results show that there were no PfM18AAP inhibitors, whereas two moderate inhibitors of the neutral aminopeptidases PfA-M1 and PfA-M17 were identified. …”
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    Screening the Medicines for Malaria Venture "Malaria Box" against the Plasmodium falciparum Aminopeptidases, M1, M17 and M18
  20. 200
    “…BACKGROUND: The incidence of M. tuberculosis (MTB) and non tuberculous Mycobacterium species (NTMs) like M. avium and M. kansasii has increased due to Human Immunodeficiency Virus (HIV) epidemic. …”
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    Use of real time polymerase chain reaction for detection of M. tuberculosis, M. avium and M. kansasii from clinical specimens
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