Mostrando 481 - 500 Resultados de 1,360,514 Para Buscar '"M', tiempo de consulta: 2.26s Limitar resultados
  1. 481
  2. 482
  3. 483
    “…N (6)-methyladenosine (m(6)A) in mRNA has emerged as a crucial epitranscriptomic modification that controls cellular differentiation and pluripotency. …”
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  4. 484
    “…However, mTOR forms two distinct complexes, mTOR complex 1 and mTOR complex 2 (mTORC1 and mTORC2), via association with a series of different components; this allows the complexes to execute their wide range of functions. …”
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  5. 485
    “…Here, we identify ammonium as a novel dose-dependent signal mediating rapid mTORC2 activation and further regulating mTORC1. …”
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  6. 486
  7. 487
    “…A master promoter of cell growth, mammalian target of rapamycin (mTOR) is upregulated in a large percentage of cancer cells. …”
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  8. 488
    “…Using selective pharmacological activation of M1 or M4 receptors along with extracellular and intracellular electrophysiology recordings from adult rat hippocampal slices, we demonstrate that activation of M1 receptors increases spontaneous spike rates of neuronal ensembles in CA1 and increases the intrinsic excitability of pyramidal neurons and interneurons. …”
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  9. 489
  10. 490
    “…An investigation on structure, stability, and magnetic properties of singly doped Au(19)M (M=Cr, Mn, and Fe) clusters is carried out by means of density functional theory calculations. …”
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  11. 491
    por Yang, Gang, Zhou, Lijun
    Publicado 2017
    “…M(IV)-incorporated zeolites have recently aroused wide interest due to outstanding catalytic effects while their active sites remain largely elusive. …”
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  12. 492
    “…In this work, the influence on growth and productivity of Tetraselmis suecica F&MM33 of bacterial communities and single bacterial isolates from the algal phycosphere was investigated. …”
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  13. 493
  14. 494
    “…N (6)-methyladenosine (m(6)A) is a reversible modification in mRNA and has been shown to regulate processing, translation and decay of mRNA. …”
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  15. 495
  16. 496
    “…However, when BMDMs are completely polarized, the levels of expression of macrophage markers and secretion of cytokines in viperin KO M1 and M2 macrophages are significantly higher than those in WT M1 and M2 macrophages. …”
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  17. 497
  18. 498
    “…We have discovered that in response to oxidative stress, transcripts are additionally m(6)A modified in their 5′ vicinity. Distinct from that of the translationally active mRNAs, this methylation pattern provides a selective mechanism for triaging mRNAs from the translatable pool to stress-induced stress granules. …”
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  19. 499
  20. 500
    “…Macrophages, whether M1 or M2 subtype, have been found to be implicated in the pathogenesis of osteoarthritis (OA). …”
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