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561por Ahmad Shariff, Siti Hajar, Daik, Rusli, Haris, Muhammad Salahuddin, Ismail, Mohamad Wafiuddin“…The 4-arm and 6-arm star-shaped PCL are synthesized with different molecular weights (5000, 10,000, 15,000 g/mol) via ROP and MPEG as the hydrophilic segment is attached via the Steglich esterification. …”
Publicado 2023
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562“…The intensity of infection of S. japonicum eggs per gram (MPEG = 4.19) among bovines is categorized as ‘light.’ …”
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563Reversion of pH-Induced Physiological Drug Resistance: A Novel Function of Copolymeric Nanoparticlespor Li, Rutian, Xie, Li, Zhu, Zhenshu, Liu, Qin, Hu, Yong, Jiang, Xiqun, Yu, Lixia, Qian, Xiaoping, Guo, Wanhua, Ding, Yitao, Liu, Baorui“…MATERIALS AND METHODS: As a model nanoparticle, Tetradrine (Tet, Pka 7.80) was incorporated into mPEG-PCL. The effectiveness of free Tet and Tet-NPs were compared at different extracellular pHs (pH values 6.8 and 7.4, respectively) by MTT assay, morphological observation and apoptotic analysis in vitro and on a murine model by tumor volume measurement, PET-CT scanning and side effect evaluation in vivo. …”
Publicado 2011
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564por Kim, Kwang‐Pyo, Cha, Jeong‐Dan, Jang, Eun‐Hye, Klumpp, Jochen, Hagens, Steven, Hardt, Wolf‐Dietrich, Lee, Kyung‐Yeol, Loessner, Martin J.“…Towards our goal to render phages less immunogenic and prolong blood circulation time, we have chemically modified intact bacteriophages by conjugation of the non‐immunogenic polymer monomethoxy‐polyethylene glycol (mPEG) to virus proteins. As a proof of concept, we have used two different polyvalent and strictly virulent phages of the Myoviridae, representing typical candidates for therapeutical approaches: Felix‐O1 (infects Salmonella) and A511 (infects Listeria). …”
Publicado 2008
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565por Zhao, Yinbo, Lin, Dayong, Wu, Fengbo, Guo, Li, He, Gu, Ouyang, Liang, Song, Xiangrong, Huang, Wei, Li, Xiang“…The obtained optimal RGD-lpNPs, composed of PLGA (poly(lactic-co-glycolic acid))–mPEG (methoxyl poly(ethylene- glycol)), RGD–polyethylene glycol (PEG)–cholesterol (Chol) copolymers and lipids, had good entrapment efficiency, submicron size and negatively neutral surface charge. …”
Publicado 2014
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566por Nguyen-Chi, Mai, Laplace-Builhe, Béryl, Travnickova, Jana, Luz-Crawford, Patricia, Tejedor, Gautier, Phan, Quang Tien, Duroux-Richard, Isabelle, Levraud, Jean-Pierre, Kissa, Karima, Lutfalla, Georges, Jorgensen, Christian, Djouad, Farida“…We generated a transgenic line whose macrophages expressing tumour necrosis factor alpha (tnfa), a key feature of classically activated (M1) macrophages, express fluorescent proteins Tg(mpeg1:mCherryF/tnfa:eGFP-F). Using 4D-confocal microscopy, we showed that both aseptic wounding and Escherichia coli inoculation triggered macrophage recruitment, some of which started to express tnfa. …”
Publicado 2015
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567por Bodaghabadi, Narges, Hajigholami, Samira, Malekshahi, Ziba Vaise, Entezari, Maliheh, Najafi, Farhood, Shirzad, Hadi, Sadeghizadeh, Majid“…METHODS: Different concentrations of co-trimoxazole and rifampicin were used for loading onto a nanostructure of synthesized monomethoxy poly(ethylene glycol)-oleate (mPEG-OA). The solubility, cytotoxicity, and efficacy of these nano-packed antibiotics on Brucella-infected murine phagocytic cells were examined, as compared with free antibiotics. …”
Publicado 2018
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568por Shi, Menghao, Zhao, Xiufeng, Zhang, Jiulong, Pan, Shuang, Yang, Chunrong, Wei, Ying, Hu, Haiyang, Qiao, Mingxi, Chen, Dawei, Zhao, Xiuli“…MATERIALS AND METHODS: In this study, a novel triblock copolymer methoxy poly(ethylene glycol)-poly(histidine)-poly(sulfadimethoxine) (mPEG-PHis-PSD, shorten as PHD) was synthesized and used to construct novel nonviral gene vector with cationic liposomes. …”
Publicado 2018
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569“…METHODS: In this study, we developed a novel gene delivery system with a self-assembly method by Methoxy polyethylene glycol-polycaprolactone (MPEG-PCL) and DOTAP(DMC). And EZH2si-DMC was used to research anti-glioma both in vitro and in vivo. …”
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570por Xia, Kun-kun, Lyu, Yong, Yuan, Wei-tang, Wang, Gui-xian, Stratton, Harrison, Zhang, Shui-jun, Wu, Jie“…Each quantal nanocarrier unit consists of a magnetite Fe(3)O(4) nanoparticle core that is further encapsulated in self-assembled micelles of the redox-responsive polyethylene glycol derivative, DSPE-SS-mPEG. The nanocarrier system was prepared using a combination of ultrasonication and dialysis to produce the microenvironment sensitive delivery system. …”
Publicado 2019
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571“…The micelle was based on methoxy poly (ethylene glycol)-poly(d,l-lactide)-poly(l-histidine) (mPEG-PLA-PHis), which integrated passive targeting, endo-lysosomal escape and pH-responsive payloads release. …”
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572por Deist, Melissa S., Gallardo, Rodrigo A., Dekkers, Jack C. M., Zhou, Huaijun, Lamont, Susan J.“…Pathways and driver genes, such as EIF2AK2, MPEG1, and TNFSF13B, associated with challenge status, dpi, and genetic line were of particular interest as candidates for disease resistance. …”
Publicado 2020
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573por Zhang, Xiaojuan, He, Chuanchuan, Liu, Xiaoguang, Chen, Yan, Zhao, Pengxuan, Chen, Chen, Yan, Ruicong, Li, Minsi, Fan, Ting, Altine, Bouhari, Yang, Tan, Lu, Yao, Lee, Robert J., Gai, Yongkang, Xiang, Guangya“…Results: The resulting nanoparticles were tunable, and they could be optimized to a monodisperse population of particles in the desired size range (40-50 nm). In addition, organic mPEG2000-silane and tetrasulfide bond-bridged organosilica were integrated into the surface and silica matrix of nanoparticles for prolonged blood circulation and tumor-selective glutathione-responsive degradation, respectively. …”
Publicado 2020
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574por Varela-Moreira, Aida, van Straten, Demian, van Leur, Heleen F., Ruiter, Ruud W.J., Deshantri, Anil K., Hennink, Wim E., Fens, Marcel H.A.M., Groen, Richard W.J., Schiffelers, Raymond M.“…Carfilzomib-loaded polymeric micelles (CFZ-PM) based on poly(ethylene glycol)-b-poly(N-2-benzoyloxypropyl methacrylamide) (mPEG-b-p(HPMA-Bz)) were prepared with the aim to improve the maximum tolerated dose of carfilzomib in a “humanized” bone marrow-like scaffold model. …”
Publicado 2020
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575“…Subsequent ring-opening polymerization (ROP) of these β-NNCA monomers provides access to oligo(β-peptoid)s and mPEG-poly(β-peptoid) diblocks with backbone chirality. …”
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576por López, Sonia, Gracia, Ignacio, García, María Teresa, Rodríguez, Juan Francisco, Ramos, María Jesús“…The conjugated coumarin with mPEG-alkyne and coumarin were evaluated for their in vitro antioxidant activities by the DPPH radical scavenging assay and were found to exhibit substantial activities. …”
Publicado 2021
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577“…The intensity of infection of Schistosoma eggs per gram (MPEG = 0.70) among bovines is categorized as light. …”
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578“…First, PEGylated Pt(IV)-prodrug was synthesized by a condensation reaction between c,c,t-[Pt(NH(3))(2)Cl(2)(OOCCH(2)CH(2)COOH)(OH)] and MPEG-PLA. Then, Pt(IV)-prodrug and indocyanine green co-encapsulated nanoparticles (Pt-INPs) were prepared through an ultrasonic emulsification method. …”
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579por Zou, Lihua“…By choosing to encode the geological parameters of the coastline with mpeg-4 and obtain the relevant data, the relevant data of the beach motion image can be obtained, so that the simulation experiment can be carried out. …”
Publicado 2021
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580por Yu, YanXin, Xu, Shan, You, Hong, Zhang, YinJie, Yang, Bo, Sun, XiaoYang, Yang, LingLin, Chen, Yue, Fu, ShaoZhi, Wu, JingBo“…PTX-NPs were prepared by a solid dispersion method using methoxy poly(ethylene glycol)–poly(ɛ-caprolactone) (MPEG–PCL), which combined with RT exerted a potent and high efficient effect against cervical cancer. …”
Publicado 2017
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