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641“…Seven hub genes (C5AR1, CXCR4, HCK, LAPTM5, MPEG1, TLR8, and TNFSF13B) were associated with those 4 immune cells (P < 0.05). …”
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642por Mittal, Ayushi, Krishna, Zabihi, Fatemeh, Rancan, Fiorenza, Achazi, Katharina, Nie, Chuanxiong, Vogt, Annika, Haag, Rainer, Sharma, Sunil K.“…A symmetrical diglycerol has been used as a core that is functionalised with alkyl chains for the creation of a hydrophobic cavity, and for aqueous solubility (polyethylene glycol) monomethyl ether (mPEG) is incorporated. Such systems can exhibit a varied self-assembly behaviour leading to the observance of different morphological structures. …”
Publicado 2022
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643por Jankowski, Maurycy, Kaczmarek, Mariusz, Wąsiatycz, Grzegorz, Konwerska, Aneta, Dompe, Claudia, Bukowska, Dorota, Antosik, Paweł, Mozdziak, Paul, Kempisty, Bartosz“…Between differentiated chondrocytes, early and late cultures, most up- and down-regulated genes in each comparison were selected for further analysis., there are several genes (e.g., MMP12, MPEG1, CHI3L1, and CD36) that could be identified as new markers of chondrogenesis and the influence of long-term culture conditions on ASCs. …”
Publicado 2022
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644“…To improve the solubility and availability in vivo, KVA-D88 was encapsulated into mPEG-b-P(CB-co-LA) nanoparticles (NPs) by solvent evaporation, with a mean particle size of 135 nm and drug loading of 4.2%. …”
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645por Tang, Longguang, Ling, Mingjian, Syeda, Madiha Zahra, Sun, Rui, He, Minghui, Mu, Qingchun, Zhu, Xiulong, Huang, Chunming, Cui, Liao“…We utilized a near-infrared dye SQ890 as both an iron-chelating and a photothermal converter agent, which was encapsulated with a GSH-sensitive polymer (PLGA-SS-mPEG), to attain the biocompatible SQ890@Fe nanoparticles (NPs). …”
Publicado 2022
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646por Zhang, Xiaohui, Cao, Lanqing, Xu, Guangmeng, He, Hongyu, Zhao, Hongyu, Liu, Tongjun“…In this study, sorafenib (Sor) and metformin (Met) co-loaded poly(ethylene glycol)-block-poly(L-glutamic acid-co-L-phenylalanine) [mPEG-b-P(Glu-co-Phe)] micelles were developed. The characterizations, drug release, in vivo biodistribution, and pharmacokinetics of the micelles were analyzed. …”
Publicado 2022
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647por Shah, Drashti, Eroy, Menitte, Fakhry, John, Moffat, Azophi, Fritz, Kevin, Cole, Houston D., Cameron, Colin G., McFarland, Sherri A., Obaid, Girgis“…We recently showed that formulating ML18J03 into 10.2 nm DSPE-mPEG(2000) micelles (Mic-ML18J03) increases its luminescence quantum yield by two orders of magnitude. …”
Publicado 2022
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648por Shang, Kun, Zhang, Lingpu, Yu, Yingjie, Xiao, Haihua, Gao, Yajuan, Yang, Liu, Huang, Jia, Song, Haiqin, Han, Hongbin“…Herein, a glutathione (GSH) sensitive amphiphilic polymer (poly (2-HD-co-HPMDA)-mPEG, PHHM) with disulfide bonds in the main chain was designed to encapsulate the USP1i as well as platinum (IV) prodrug (Pt (IV)–C12), resulting in the formation of composite nanoparticles, i.e., NP-Pt-USP1i. …”
Publicado 2023
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649por Wang, Jie, Wang, Fengling, Xie, Dandan, Zhou, Min, Liao, Jiaxing, Wu, Hongliang, Dai, Yue, Huang, Jingbin, Zhao, Yu“…Co-NPs were composed of PLGA encapsulated Suc and Dox as hydrophobic cores and DSPE-mPEG(2000) as surface modification materials. With an appropriate particle size (122.4 nm) and a negatively charged surface (−6.77 mV) we could achieve prolonged blood circulation. …”
Publicado 2023
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650por Zhang, Kunfeng, Fu, Jingxin, Liu, Xiaorui, Guo, Yifei, Han, Meihua, Liu, Meifeng, Wang, Xiangtao“…The TH conjugate could also co-assembly with mPEG(3000)-PLGA(5000) into nanoparticles (TH-NPs), with a mean diameter of 86.41 nm, a PDI value of 0.256 and a zeta potential of −0.125 mV. …”
Publicado 2023
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651por Parchami, Mastaneh, Haghiralsadat, Fateme, Sadeghian-Nodoushan, Fatemeh, Hemati, Mahdie, Shahmohammadi, Sajjad, Ghasemi, Nasrin, Sargazi, Ghasem“…The final selected formulation was superficially modified using DSPE-mPEG2000. A three-dimensional hydrogel culture model with appropriate structure and porosity was synthesized using sodium alginate and calcium chloride as crosslinks for hydrogel. …”
Publicado 2023
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652“…The study involved compressing a set of test dynamic point clouds using the MPEG V-PCC (Video-based Point Cloud Compression) codec at 5 different levels of compression and applying simulated packet losses with three packet loss rates (0.5%, 1% and 2%) to the V-PCC sub-bitstreams prior to decoding and reconstructing the dynamic point clouds. …”
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653por Hu, Yun-Ting, Wu, Kai-Xuan, Wang, Xiao-Tong, Zhao, Yuan-Yi, Jiang, Xiao-Yong, Liu, Dan, Tong, Man-Li, Liu, Li-Li“…Here, we found that Tp can exert significant toxic effects on microglia in vivo in Tg (mpeg1: EGFP) transgenic zebrafish embryos. Single-cell RNA sequencing results showed that Tp downregulated autophagy-related genes in human HMC3 microglial cells, which is negatively associated with apoptotic gene expression. …”
Publicado 2023
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654por Hebels, Erik R., van Steenbergen, Mies J., Haegebaert, Ragna, Seinen, Cornelis W., Mesquita, Barbara S., van den Dikkenberg, Antoinette, Remaut, Katrien, Rijcken, Cristianne J. F., van Ravensteijn, Bas G. P., Hennink, Wim E., Vermonden, Tina“…Previously, CCPMs based on methoxy poly(ethylene glycol)-b-poly[N-(2-hydroxypropyl) methacrylamide-lactate] (mPEG-b-PHPMAmLac(n)) modified with thioesters were crosslinked via native chemical ligation (NCL, a reaction between a cysteine residue and thioester resulting in an amide bond) using a bifunctional cysteine containing crosslinker. …”
Publicado 2023
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655por Shao, Runrun, Qiao, Xiaofang, Cao, Linlin, Man, Jianliang, Guo, Lingyun, Li, Lanlan, Liu, Wen, Li, Lihong, Wang, Bin, Guo, Lixia, Ma, Sufang, Zhang, Boye, Wang, Haojiang, Yan, Lili“…The nanoparticles were further modified with Methoxypoly(Ethylene Glycol) 2000 (mPEG-NH(2)) to improve their biocompatibility, resulting in the formation of MoS(2)@MnO(2)-PEG. …”
Publicado 2023
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656por Huang, Zhifeng, Wang, Huiyan, Lu, Meifei, Sun, Chuanchuan, Wu, Xiaoping, Tan, Yi, Ye, Chaohui, Zhu, Guanghui, Wang, Xiaojie, Cai, Lu, Li, Xiaokun“…At N-terminal residue rhFGF21 was site-selectively PEGylated with mPEG20 kDa-butyraldehyde. The PEGylated rhFGF21 was purified to near homogeneity by Q Sepharose anion-exchange chromatography. …”
Publicado 2011
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657por Du, Zhen-Yu, Ma, Tao, Lock, Erik-Jan, Hao, Qin, Kristiansen, Karsten, Frøyland, Livar, Madsen, Lise“…Similarly, expressions of marker genes of macrophage and monocyte (MPEG-1, CD68, F4/80, CD64) were higher in the stromal vascular fraction (SVF) isolated from inguinal ATE than that from epididymal ATE. …”
Publicado 2011
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658“…Initially developed in 1992 as an MR imaging agent, the family of protected graft copolymers (PGC) is based on a conjugate of polylysine backbone to which methoxypoly(ethylene glycol) (MPEG) chains are covalently linked in a random fasion via N-ε-amino groups. …”
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659por Yeon Kwon, Doo, Seon Kwon, Jin, Hun Park, Seung, Hun Park, Ji, Hee Jang, So, Yun Yin, Xiang, Yun, Jeong-Ho, Ho Kim, Jae, Hyun Min, Byoung, Hee Lee, Jun, Kim, Wan-Doo, Suk Kim, Moon“…We used solid freeform fabrication (SFF) with biodegradable polyesters (MPEG-(PLLA-co-PGA-co-PCL) (PLGC)) to fabricate a computer-designed scaffold. …”
Publicado 2015
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660por Ochi, Mohammad Mahdi, Amoabediny, Ghasem, Rezayat, Seyed Mahdi, Akbarzadeh, Azim, Ebrahimi, Bahman“…Liposomes that co-encapsulated silibinin and glycyrrhizic acid were prepared with a specified molar ratio of dipalmitoylphosphatidylcholine (DPPC), cholesterol (CHOL), and methoxy-polyethylene glycol 2000 (PEG2000)–derived distearoyl phosphatidylethanolamine (mPEG2000-DSPE). We used the MTT technique to assess cytotoxicity for various concentrations of co-encapsulated nano-liposomes, free silibinin (25% w/v) and glycyrrhizic acid (75% w/v) on HepG2 and fibroblast cell lines over a 48-hour period. …”
Publicado 2016
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