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701por Xie, Fang, Zhang, Luchen, Shi, Sanyuan, Zheng, Anjie, Di, Jiaxing, Jin, Shanshan, Miao, Xuguang, Wu, Fenglan, Chen, Xiaolong, Zhang, Yanhong, Wei, Xiaohui, Xu, Yuhong“…Abbreviation: Chimeric antigen receptor T cells (CAR-T cells), Cytokine release syndrome (CRS) Cytotoxic T cell (CTL) Effector: target ratios (E:T ratios), Heavy chain (HC) Immune-related adverse events (irAE), Large unilamellar vesicle (LUV), Peripheral blood mononuclear cells (PBMCs, Single-chain variable fragment (scFv), T cell-dependent bispecific antibody (TDB), T cell redirecting antibody fragment-anchored liposomes (TRAFsomes), Methoxy poly-(ethylene glycol) (mPEG)…”
Publicado 2022
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702por Fan, Huimin, Yan, Ting, Chen, Shuang, Du, Zhong, Alimu, Gulinigaer, Zhu, Lijun, Ma, Rong, Tang, Xiaohui, Heng, Youqiang, Alifu, Nuernisha, Zhang, Xueliang“…Furthermore, to improve the biocompatibility of the NPs, methoxy polyethylene glycol amine (mPEG-NH(2)) was modified via a Michael addition to form a novel kind of IR820@PDA@PEG NPs. …”
Publicado 2022
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703“…Monocytes annotated 3 subclusters including DC, macrophage, and monocytes. Hub genes of Ctss, Mpeg1, Cybb, H2-Ab1, Ly86, CD74, and Lgals3 were highly expressed in monocytes cluster. …”
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704“…Herein, methoxypolyethylene glycol amine (mPEG-NH(2)) modified polydopamine nanoparticles (PDA-PEG NPs) were synthesized for treating early OA. …”
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705por Wang, Yinan, Su, Yanan, Yang, Yunqiao, Jin, Huan, Wu, Moli, Wang, Qian, Sun, Pengyuan, Zhang, Jianbin, Yang, Xiaobo, Shu, Xiaohong“…The aim of this study was to construct a folate modified pterostilbene (Pt) loaded polymeric micellar delivery system (F-Pt/M) with mPEG-PCL as carrier material to aim at penetrating the BBB for brain tissue targeting via receptor-mediated endocytosis. …”
Publicado 2022
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706por De Lorenzi, Federica, Rizzo, Larissa Yokota, Daware, Rasika, Motta, Alessandro, Baues, Maike, Bartneck, Matthias, Vogt, Michael, van Zandvoort, Marc, Kaps, Leonard, Hu, Qizhi, Thewissen, Marielle, Casettari, Luca, Rijcken, Cristianne J. F., Kiessling, Fabian, Sofias, Alexandros Marios, Lammers, Twan“…CriPec® technology enables the generation of core‐crosslinked polymeric micelles (CCPMs) based on thermosensitive (mPEG-b-pHPMAmLac(n)) block copolymers, with high drug loading capacity, tailorable size, and controlled drug release kinetics. …”
Publicado 2022
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707por Casadidio, Cristina, Hartman, Jet E. M., Mesquita, Bárbara S., Haegebaert, Ragna, Remaut, Katrien, Neumann, Myriam, Hak, Jaimie, Censi, Roberta, Di Martino, Piera, Hennink, Wim E., Vermonden, Tina“…For this, a methoxypoly(ethylene glycol) poly(2-(dimethylamino)ethyl methacrylate) (mPEG-pDMAEMA) diblock copolymer was synthesized as a polymeric carrier for NA binding and condensation with either plasmid DNA (pDNA) or short interfering RNA (siRNA). …”
Publicado 2023
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708por Chuang, Wen-Han, Pislyagin, Evgeny, Lin, Liang-Yu, Menchinskaya, Ekaterina, Chernikov, Oleg, Kozhemyako, Valery, Gorpenchenko, Tatiana, Manzhulo, Igor, Chaikina, Elena, Agafonova, Irina, Silchenko, Alexandra, Avilov, Sergey, Stonik, Valentin, Tzou, Shey-Cherng, Aminin, Dmitry, Wang, Yun-Ming“…Notably, loading near-infrared (NIR) fluorochrome-labeled nanoparticles, MnMEIO-mPEG-CyTE777, into macrophages substantiated that M1 macrophages can target and penetrate tumor tissues in vivo efficiently. …”
Publicado 2023
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709por Karlsson, Karl R., Cowley, Sally, Martinez, Fernando O., Shaw, Michael, Minger, Stephen L., James, William“…We found that esMCs and esMDMs expressed well-defined markers of the mononuclear phagocyte system including PU-1, C/EBPα, EMR1, and EMR2, MPEG1, CD1c, CD4, CD18, CD32, CD33, CD68, cathepsins and serine carboxypeptidase. …”
Publicado 2008
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710por Inoue, Satoshi, Patil, Rameshwar, Portilla-Arias, Jose, Ding, Hui, Konda, Bindu, Espinoza, Andres, Mongayt, Dmitriy, Markman, Janet L., Elramsisy, Adam, Phillips, H. Westley, Black, Keith L., Holler, Eggehard, Ljubimova, Julia Y.“…Controls included (3) P with 2C5 but without AON (P/2C5), (4) PBS, and (5) P with PEG and leucine ester (LOEt) for endosomal escape (P/mPEG/LOEt). Drugs were injected intravenously to MDA-MB-468 TNBC bearing mice. …”
Publicado 2012
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711por Buga, Ana Maria, Margaritescu, Claudiu, Scholz, Claus Juergen, Radu, Eugen, Zelenak, Christine, Popa-Wagner, Aurel“…The angiogenic response in aged rats was further diminished by the persistent upregulation of “inflammatory” genes (Cxcl12, Mmp8, Mmp12, Mmp14, Mpeg1, Tnfrsf1a, Tnfrsf1b) and vigorous expression of genes required for the buildup of the fibrotic scar (Cthrc1, Il6ra, Il13ar1, Il18, Mmp2, Rassf4, Tgfb1, Tgfbr2, Timp1). …”
Publicado 2014
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712por Kim, Tae Hyung, Lee, Eun-Ju, Choi, Ji-Hye, Yim, Sun Young, Lee, Sunwon, Kang, Jaewoo, Lee, Yoo Ra, Lee, Han Ah, Choi, Hyuk Soon, Kim, Eun Sun, Keum, Bora, Seo, Yeon Seok, Yim, Hyung Joon, Jeen, Yoon Tae, Chun, Hoon Jai, Lee, Hong Sik, Kim, Chang Duck, Woo, Hyun Goo, Um, Soon Ho“…The flanking genes at these loci including MPEG1, DTX4, MTX3, and HOXA13 were suggested to have functional significance. …”
Publicado 2018
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713por Rougeot, Julien, Torraca, Vincenzo, Zakrzewska, Ania, Kanwal, Zakia, Jansen, Hans J., Sommer, Frida, Spaink, Herman P., Meijer, Annemarie H.“…We made use of the well-established mpeg1, mpx, and lck fluorescent reporter lines to sort and sequence the transcriptome of larval macrophages, neutrophils, and lymphoid progenitor cells, respectively. …”
Publicado 2019
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714por Yin, Peidi, Li, Huifeng, Ke, Chao, Cao, Guangxu, Xin, Xiaoqian, Hu, Junjiao, Cai, Xiangran, Li, Lingfeng, Liu, Xiaowen, Du, Bin“…METHODS: A new oligonucleotide nanoformulation (Au@PP)/poly(I:C)) was constructed by coating gold nanoparticles (AuNPs) with methoxypolyethylene glycol (mPEG)-detachable (d)-polyethyleneimine (PEI) (Au@PP) followed by inducing the formation of electrostatic interactions with polyinosinic-polycytidylic acid (poly(I:C)). …”
Publicado 2020
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715por Shen, Rong, Xu, Peng‐Peng, Wang, Nan, Yi, Hong‐Mei, Dong, Lei, Fu, Di, Huang, Jin‐Yan, Huang, Heng‐Ye, Janin, Anne, Cheng, Shu, Wang, Li, Zhao, Wei‐Li“…MYD88 was frequently mutated in patients with multiple ENI, co‐occurred with mutations in CD79B, PIM1, TBL1XR1, BTG1, MPEG1, and PRDM1, and correlated with invasion of the bones, kidney/adrenal glands, breasts, testes, skin, and uterus/ovaries. …”
Publicado 2020
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716por Yan, Tingyu, Ma, Zhongxu, Liu, Jingjing, Yin, Na, Lei, Shizhen, Zhang, Xinxin, Li, Xuedong, Zhang, Yu, Kong, Jun“…To decrease postsurgical inflammation, prevent infection and reduce the incidence of secondary cataract, we built a temperature-sensitive drug delivery system carrying dexamethasone, moxifloxacin and genistein nanostructured lipid carrier (GenNLC) modified by mPEG-PLA based on F127/F68 as hydrogel. Characterizations and release profiles of the drug delivery system were studied. …”
Publicado 2021
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717por Wang, Shuhang, Gou, Jingxin, Wang, Yue, Tan, Xinyi, Zhao, Linxuan, Jin, Xiangqun, Tang, Xing“…MATERIALS AND METHODS: Sodium poly(α-l-glutamic acid)-graft-methoxy-polyethylene glycol (PLG-G-PEG(5K)) was used to prepare NVB-loaded NVB-PMs and CDDP-loaded CDDP-PMs that were co-encapsulated into liposomes by a reverse evaporation method, yielding NVB and CDDP co-delivery liposomes (CoNP-lips) composed of egg phosphatidyl lipid-80/cholesterol/DPPG/DSPE-mPEG(2000) at a molar ratio of 52:32:14:2. The CoNP-lips were characterized in terms of particle size, zeta potential, drug content, encapsulation efficiency, and structural properties. …”
Publicado 2021
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718por Chen, Xiangjun, Guo, Rong, Wang, Changrong, Li, Keke, Jiang, Xinyu, He, Huayu, Hong, Wei“…The AZM-SCSMs was composed of poly(l-lactide)-polyetherimide-hyd-methoxy polyethylene glycol (PLA-PEI-hyd-mPEG). It was noteworthy that the pH-sensitive acylhydrazone bond could be cleaved in acidic biofilm microenvironment, releasing the secondary AZM-loaded cationic micelles based on PLA-PEI (AZM-SCMs) without destroying the micellar integrity, which could tailor drug-bacterium interaction using micelles through electrostatic attraction. …”
Publicado 2021
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719por Deng, Xuanru, Liu, Hongxing, Xu, Yuan, Chan, Leung, Xie, Jun, Xiong, Zushuang, Tang, Zheng, Yang, Fang, Chen, Tianfeng“…RESULTS: Herein, black phosphorus nanosheets (BPs) covalently with mono-dispersed and superparamagnetic ferrous selenide (FeSe(2)) to construct heteronanostructure nanoparticles modified with methoxy poly (Ethylene Glycol) (mPEG-NH(2)) to obtain good water solubility for MRI-guided photothermal tumor therapy is successfully designed. …”
Publicado 2021
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720por He, Pan, Tang, Bingtong, Li, Yusheng, Zhang, Yu, Liu, Xinming, Guo, Xin, Wang, Dong, She, Peng, Xiao, Chunsheng“…PURPOSE: In this study, we present the feasibility of an oxidation-sensitive PEGylated alternating polyester, methoxyl poly(ethylene glycol)-block-poly(phthalic anhydride-alter-glycidyl propargyl ether) (mPEG-b-P(PA-alt-GPBAe)), as novel nanocarrier for curcumin (CUR), and explore the application in anti-inflammatory therapy. …”
Publicado 2021
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