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181por Nakai, Kumiko, Kawato, Takayuki, Morita, Toyoko, Yamazaki, Yoji, Tanaka, Hideki, Tonogi, Morio, Oki, Hidero, Maeno, Masao“…Gene and protein expression levels of transcription factors and ECM proteins were determined using real-time PCR and Western blotting, respectively. RESULTS: Runx2, Msx2, and osteocalcin expression significantly decreased with Ang II compared to the control, whereas AJ18 expression significantly increased. …”
Publicado 2015
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182por Nagel, Stefan, Pommerenke, Claudia, Meyer, Corinna, Kaufmann, Maren, Drexler, Hans G., MacLeod, Roderick A.F.“…Accordingly, expression profiling and functional analyses demonstrated that AUTS2 activated while PCGF5 repressed transcription of NKL homeobox gene MSX1 in T-ALL cells. Forced expression and pharmacological inhibition of EZH2 in addition to H3K27me3 analysis indicated that PRC2 repressed MSX1 as well. …”
Publicado 2016
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183por Koop, Demian, Cisternas, Paula, Morris, Valerie B., Strbenac, Dario, Yang, Jean Yee Hwa, Wray, Gregory A., Byrne, Maria“…RESULTS: BMP2/4, and the putative downstream genes, Six1/2, Eya, Tbx2/3 and Msx were expressed in the earliest morphological manifestation of pentamery during development, the five hydrocoele lobes. …”
Publicado 2017
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184por Nagel, Stefan, Pommerenke, Claudia, Meyer, Corinna, Kaufmann, Maren, MacLeod, Roderick A.F., Drexler, Hans G.“…Finally, HLX inhibited transcription of B-cell differentiation factors MSX1, BCL11A and SPIB and of pro-apoptotic factor BCL2L11/BIM, thereby suppressing Etoposide-induced cell death. …”
Publicado 2018
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185por Liang, Jia-Wei, Fang, Zheng-Yu, Huang, Yong, Liuyang, Zhen-yu, Zhang, Xiao-Lin, Wang, Jing-Lin, Wei, Hui, Wang, Jian-Zhi, Wang, Xiao-Chuan, Zeng, Ji, Liu, Rong“…Through analysis of the two modules, we found that metallothionein (MT), Notch2, MSX1, ADD3, and RAB31 were highly correlated with AD phenotype. …”
Publicado 2018
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186por Zhao, Manzhu, Wang, Yingying, Li, Gang, Li, Jun, Yang, Kun, Liu, Chang, Wen, Xiujie, Song, Jinlin“…The molecular signatures alkaline phosphatase (ALP), collagen type 1 (Col1), melanoma‐associated antigen (Mage)‐D1, bone sialoprotein (BSP), osteocalcin (OCN), osteopontin (OPN), distal‐less homeobox 1 (Dlx1) and Msh homeobox 1 (Msx1) were examined in vitro in EMSCs isolated from p75NTR(+/+) and p75NTR(ExIII−/−) mice. …”
Publicado 2020
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187por Vu, Tri H., Takechi, Masaki, Shimizu, Miki, Kitazawa, Taro, Higashiyama, Hiroki, Iwase, Akiyasu, Kurihara, Hiroki, Iseki, Sachiko“…Since dermal cells express Runx2 and Msx2 in the control, osteogenic potential in dermal cells seemed to be inhibited by an anti-osteogenic function of Msx2 in normal context. …”
Publicado 2021
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188por Hu, Xiaoxiao, Lin, Chensheng, Ruan, Ningsheng, Huang, Zhen, Zhang, Yanding, Hu, Xuefeng“…We showed that pSMAD1/5/8 is required for the expression of Msh homeobox 1 (MSX1), a well-defined BMP signaling target gene, in human dental mesenchyme, but the typical BMP canonical signaling is in fact not operating in the early human developing tooth, as evidenced by the absence of pSMAD1/5/8-SMAD4 complexes in the dental mesenchyme and translocation of pSMAD1/5/8, and the expression of MSX1 induced by BMP4 is mothers against decapentaplegic homolog 4 (SMAD4)-independent in human dental mesenchymal cells. …”
Publicado 2022
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189M2c Macrophages enhance phalange regeneration of amputated mice digits in an organ co-culture systempor Bijarchian, Fatemeh, Taghiyar, Leila, Azhdari, Zahra, Baghaban Eslaminejad, Mohamadreza“…This regrowth was related to enhanced Msh homeobox-1 (Msx1), Msh homeobox-2 (Msx2), and bone morphogenic protein-4 (Bmp4) genes. …”
Publicado 2021
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190por Hamilton, Joanna S., Piria, Marina, Gavrilović, Ana, Mrkonjić Fuka, Mirna, Svečnjak, Lidija, Nikolić, Slađana, Bakiu, Rigers, Gardner, Jonathan P. A.“…Conserved domain searches revealed a similar structure to the transcriptional regulator Msx2‐interacting protein. The BLASTp search also returned significant alignments to Msx2‐interacting proteins in Mytilus coruscus, Crassostrea virginica, and Haliotis rubra. …”
Publicado 2023
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191“…Genes responsible for non syndromic oligodontia are found to be MSX1 and PAX9 genes. In this case report a 13 year old boy is presented who had absence of all four second permanent molars and permanent mandibular incisors. …”
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192por Tapia, Alejandro, Vilos, Cristian, Marín, Juan Carlos, Croxatto, Horacio B, Devoto, Luigi“…Those more consistently increased were C4BPA, SPP1, APOD, CD55, CFD, CLDN4, DKK1, ID4, IL15 and MAP3K5 whereas the more consistently decreased were OLFM1, CCNB1, CRABP2, EDN3, FGFR1, MSX1 and MSX2. Functional annotation of CERTL showed it was enriched with transcripts related to the immune response, complement activation and cell cycle regulation. …”
Publicado 2011
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193por Lin, Chih-Pei, Huang, Po-Hsun, Lai, Chung Fang, Chen, Jaw-Wen, Lin, Shing-Jong, Chen, Jia-Shiong“…Furthermore, p65, p47 and TNFR1 siRNAs inhibited the TNF-α-mediated stimulation of BMP-2, MSX2, RUNX2 expression. SIM, APO, and NAC either partially inhibit or completely block the TNF-α induced H(2)O(2) or superoxide production. …”
Publicado 2015
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194“…The expression of cyclin-dependent kinase inhibitor (P21), muscle segment homeobox genes 2 (Msx2), which are the target genes of the BMP signaling pathway, and laminin 3, the downstream factor of Msx2, were all significantly decreased in the ameloblasts of the cKO mice compared to the control mice. …”
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195“…It was observed that 1,25(OH)(2)D(3) significantly decreased the expression levels of BMP2, Runx2, Msx2, OPN and OCN, and reduced ALP activity and the calcified area in BMSCs, whereas these effects were rescued by BMP2 overexpression. …”
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196“…Removing DAPT significantly impacted MSX2, OTX2, EN1, and KCNJ6. In the absence of any stressful stimuli, we suggest that these culture additives should be viewed as mDA phenotype-modifying, rather than neuroprotective. …”
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197por Sharma, Abhishek, Sharma, Abhinav, Averbukh, Moshe, Jately, Vibhu, Rajput, Shailendra, Azzopardi, Brian, Lim, Wei Hong“…France solar cell, LSM20 PV module, Solarex MSX-60 PV module, and SS2018P PV module. These four cell/modules are built using different technologies. …”
Publicado 2023
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198por Ghanem, Nasser, Hölker, Michael, Rings, Franca, Jennen, Danyel, Tholen, Ernst, Sirard, Marc-André, Torner, Helmut, Kanitz, Wilhelm, Schellander, Karl, Tesfaye, Dawit“…The expression profile of 8 (80%) transcripts (ANAXA2, FL396, S100A10, RPL24, PP, PTTG1, MSX1 and BMP15) was in agreement with microarray data. …”
Publicado 2007
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199por Hosen, Mohammad J, Coucke, Paul J, Le Saux, Olivier, De Paepe, Anne, Vanakker, Olivier M“…RESULTS: We demonstrate the upregulation of the BMP2-SMADs-RUNX2 and TGFβ-2-SMAD2/3 pathway, co-localizing with the mineralization sites, and the involvement of MSX2-canonical Wnt signalling. Further, we show that apoptosis is also involved in PXE with activation of Caspases and BCL-2. …”
Publicado 2014
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200por Wang, Shuangshuang, Hu, Siwang, Wang, Jian, Liu, Yahui, Zhao, Ruochi, Tong, Maoqing, Cui, Hanbin, Wu, Nan, Chen, Xiaomin“…Expression of BMP2, BMPR1A, BMPR1B, BMPR2, msh homeobox 2 (Msx2), Runt-related transcription factor 2 (Runx2), and osteocalcin (OC), representative osteoblastic markers, was assessed using real-time polymerase chain reaction analysis while the protein expression of BMP2, Runx2, and phosphorylated Smad1/5/8 was detected by western blot analysis. …”
Publicado 2018
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