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21por Khasawneh, Ramada R., Kist, Ralf, Queen, Rachel, Hussain, Rafiqul, Coxhead, Jonathan, Schneider, Jürgen E., Mohun, Timothy J., Zaffran, Stéphane, Peters, Heiko, Phillips, Helen M., Bamforth, Simon D.“…The transcription factors Pax9 and Msx1 genetically interact during mouse craniofacial morphogenesis, and mice deficient for either gene display abnormal tooth and palate development. …”
Publicado 2021
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22por Medio, Marie, Yeh, Erika, Popelut, Antoine, Babajko, Sylvie, Berdal, Ariane, Helms, Jill A.“…The transcriptional repressor Msx1 is a key participant in these molecular events, as demonstrated by the palatal clefting phenotype observed in Msx1(−/−) embryos. …”
Publicado 2012
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23por Atsawasuwan, Phimon, Lu, Xuanyu, Ito, Yoshihiro, Zhang, Youbin, Evans, Carla A., Luan, Xianghong“…The reduction of Msx2 expression as a result of Ambn overexpression was further enhanced in the presence of the MEK/ERK pathway inhibitor O126. …”
Publicado 2013
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24“…For example, variations in the homeobox gene family member MSX1, including a CA repeat located within its single intron, may play a role in clefting. …”
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25por Goto, Noriko, Fujimoto, Katsumi, Fujii, Sakiko, Ida-Yonemochi, Hiroko, Ohshima, Hayato, Kawamoto, Takeshi, Noshiro, Mitsuhide, Shukunami, Chisa, Kozai, Katsuyuki, Kato, Yukio“…Although MSX1 regulates osteoblast differentiation in the cranial bone of young animal, little is known about the contribution of MSX1 to the osteogenic potential of human cells. …”
Publicado 2016
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26por Eppich, Simon, Kuhn, Christina, Schmoeckel, Elisa, Mayr, Doris, Mahner, Sven, Jeschke, Udo, Gallwas, Julia, Heidegger, Helene Hildegard“…One potential factor could be the protein MSX1, a transcription repressor, that has an inhibitory effect on the cell cycle. …”
Publicado 2020
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27por Najmuddin, Mohammed, Saheb, Safeena Abdul Khader, Alharbi, Abdulrahman Nahi, Alsobil, Fahad Mohammed, Jhugroo, Chitra, Khan, Aftab Ahmed, Divakar, Darshan Devang, Naik, Sachin, Khanagar, Sanjeev BalappaEnlace del recurso
Publicado 2020
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28Association of Polymorphic and Haplotype Variants of the MSX1 Gene and the Impacted Teeth Phenomenon“…In this study it has been assumed that tooth impaction—at least to some extent—also depends on the presence of specific genetic markers, especially allelic variants of the MSX1 gene. The primary objective of the study was to evaluate the suitability of selected molecular markers located within the MSX1 gene for the determination of the risk of tooth impaction in particular patients. …”
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29por Adachi, Junya, Aoki, Yoshihiko, Tatematsu, Tadashi, Goto, Hiroki, Nakayama, Atsuo, Nishiyama, Takeshi, Takahashi, Katsu, Sana, Masatoshi, Ota, Akiko, Machida, Junichiro, Nagao, Toru, Tokita, Yoshihito“…We investigated the etiology of human tooth agenesis by exome analysis in Japanese patients, and found a previously undescribed heterozygous deletion (NM_002448.3(MSX1_v001):c.433_449del) in the first exon of the MSX1 gene. …”
Publicado 2021
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30“…Dlx2, Lymphoid Enhancer Factor (Lef-1) and Msx2 transcription factors are required for several developmental processes. …”
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31por Ayers, Sloan, Graf, Tyler N., Adcock, Audrey F., Kroll, David J., Shen, Qi, Swanson, Steven M., Matthew, Susan, Carcache de Blanco, Esperanza J., Wani, Mansukh C., Darveaux, Blaise A., Pearce, Cedric J., Oberlies, Nicholas H.“…Two new xanthone-anthraquinone heterodimers, acremoxanthone C (5) and acremoxanthone D (2), have been isolated from an extract of an unidentified fungus of the Order Hypocreales (MSX 17022) by bioactivity-directed fractionation as part of a search for anticancer leads from filamentous fungi. …”
Publicado 2011
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32por Yamaguchi, Seishi, Machida, Junichiro, Kamamoto, Munefumi, Kimura, Masashi, Shibata, Akio, Tatematsu, Tadashi, Miyachi, Hitoshi, Higashi, Yujiro, Jezewski, Peter, Nakayama, Atsuo, Shimozato, Kazuo, Tokita, Yoshihito“…Since MSX1 and PAX9 are linked to the pathogenesis of nonsyndromic tooth agenesis, we performed detailed mutational analysis of these two genes sampled from Japanese patients. …”
Publicado 2014
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33por Esteves, Francisco F., Springhorn, Alexander, Kague, Erika, Taylor, Erika, Pyrowolakis, George, Fisher, Shannon, Bier, Ethan“…The fates of these neural progenitor cells are determined in part by three conserved transcription factors: vnd/nkx2.2, ind/gsh and msh/msx in Drosophila melanogaster/vertebrates, which are expressed in corresponding non-overlapping patterns along the dorsal-ventral axis. …”
Publicado 2014
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34por Ma, Zhangjing, Shi, Huiyuan, Shen, Yi, Li, Huixia, Yang, Yu, Yang, Jiange, Zhao, Hui, Wang, Gang, Wang, Jingqiang“…The nuclear periphery localization of Msx1 and its protein partners is required for Msx1’s function of preventing myogenic precursors from pre-maturation through repressing target myogenic regulatory genes. …”
Publicado 2019
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35“…CONCLUSION: Our study identified that the gene of MSX1 promised to be the specific indicator and therapeutic target for progestin resistance. …”
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36por Lee, Yeongun, Dho, So Hee, Lee, Jiyeon, Hwang, Ji-Hyun, Kim, Minjung, Choi, Won-Young, Lee, Jin-Young, Lee, Jongwon, Chang, Woochul, Lee, Min Young, Choi, Jungmin, Kim, Tae-You, Kim, Lark Kyun“…Our discovery of methylation markers in the PDX1, EN2, and MSX1 genes suggests their promising performance as prognostic markers and their clinical application in CRC patients.…”
Publicado 2022
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37por Zhang, Xianzhu, Jiang, Wei, Xie, Chang, Wu, Xinyu, Ren, Qian, Wang, Fei, Shen, Xilin, Hong, Yi, Wu, Hongwei, Liao, Youguo, Zhang, Yi, Liang, Renjie, Sun, Wei, Gu, Yuqing, Zhang, Tao, Chen, Yishan, Wei, Wei, Zhang, Shufang, Zou, Weiguo, Ouyang, Hongwei“…Notably, we find a local expansion of resident Msx1+ skeletal stem cells after transplantation of the in situ cell culture system. …”
Publicado 2022
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38por Ma, Zhangjing, Shi, Huiyuan, Shen, Yi, Li, Huixia, Yang, Yu, Yang, Jiange, Zhao, Hui, Wang, Gang, Wang, JingqiangEnlace del recurso
Publicado 2023
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39por Austin, Eric D., Menon, Swapna, Hemnes, Anna R., Robinson, Linda R., Talati, Megha, Fox, Kelly L., Cogan, Joy D., Hamid, Rizwan, Hedges, Lora K., Robbins, Ivan, Lane, Kirk, Newman, John H., Loyd, James E., West, James“…The transcription factor MSX1, which is known to regulate BMP signaling, was the most upregulated gene (4×) in IPAH patients. …”
Publicado 2011
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40“…Recent studies revealed the roles of MSX2 in the development of carcinoma of various origins including pancreas. …”
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