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481por Kim, Hyun Je, Shim, Joon Ho, Park, Ji-Hye, Shin, Hyun Tae, Shim, Jong Sup, Jang, Kee-Taek, Park, Woong-Yang, Lee, Kyung-Hoon, Kwon, Eun Ji, Jang, Hyung-Suk, Yang, Hanseul, Lee, Jong Hee, Yang, Jun-Mo, Lee, Dongyoun“…In situ RNA hybridization demonstrated the localization of RSPO4, MSX1 and WIF1 in onychofibroblasts suggesting the activation of WNT signaling. …”
Publicado 2021
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482“…The expression levels of Nox4, Mmrn1, Mcm5, Msx1 and Fgf5 mRNAs were validated by qRT-PCR and found to be consistent with the RNA-Seq data, confirming a strong correlation between the two approaches. …”
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483“…Moreover, the lactation potential of bMECs was undermined due to significantly downregulated SOSTDC1, WNT7B, MSX1, and bta-miR-2425-5p. In summary, bMECs may not be good at going head-to-head with the pathogens; they seem to be mainly charged with sending out signals for help and anti-apoptosis for maintaining lives after LPS induction.…”
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484por Huang, Tao, Nazir, Bisma, Altaf, Reem, Zang, Bolun, Zafar, Hajra, Paiva-Santos, Ana Cláudia, Niaz, Nabeela, Imran, Muhammad, Duan, Yongtao, Abbas, Muhammad, Ilyas, Umair“…Moreover, several transcriptional factors such as DBX2, HOXB7, POU3F4, MSX2, EBF1, and E4F1 showed association with these identified differentially expressed genes. …”
Publicado 2022
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485por Shen, Pei, Chen, Lu, Zhang, Dahe, Xia, Simo, Lv, Zhuman, Zou, Duohong, Zhang, Zhiyuan, Yang, Chi, Li, Wenlin“…The cells stably expressed cranial neural crest-derived mandibular condylar cartilage markers, such as MSX1, FOXC1 and FOXC2. Compared with chondroprogenitors from iPSCs via the paraxial mesoderm, ECCs had single-cell transcriptome profiles similar to condylar chondrocytes. …”
Publicado 2022
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486por Muok, Laureana, Liu, Chang, Chen, Xingchi, Esmonde, Colin, Arthur, Peggy, Wang, Xueju, Singh, Mandip, Driscoll, Tristan, Li, Yan“…Compared to the −CHIR group, the +CHIR group showed an upregulation of 6 out of 10 tested ChP genes, including CLIC6 (2-fold), PLEC (4-fold), PLTP (2–4-fold), DCN (~7-fold), DLK1 (2–4-fold), and AQP1 (1.4-fold), and a downregulation of TTR (0.1-fold), IGFBP7 (0.8-fold), MSX1 (0.4-fold), and LUM (0.2–0.4-fold). When exposed to amyloid beta 42 oligomers, the +CHIR group had a more sensitive response as evidenced by the upregulation of inflammation-related genes such as TNFα, IL-6, and MMP2/9 when compared to the −CHIR group. …”
Publicado 2023
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487por Srila, Witsanu, Baumann, Martina, Riedl, Markus, Rangnoi, Kuntalee, Borth, Nicole, Yamabhai, Montarop“…Analysis of pool cultures and subclones after a single round of 25 µM methionine sulfoxinime (MSX) selection indicated that for CHO-K1 the double GS5,1-KO was more efficient as in the case of a single GS5-KO the GS1 gene was upregulated. …”
Publicado 2023
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488por Meem, Tahera Mahnaz, Khan, Umama, Mredul, Md Bazlur Rahman, Awal, Md Abdul, Rahman, Md Habibur, Khan, Md Salauddin“…Ten hub genes among them (DUSP1, NKX2-5, GLI1, KLF4, SCNN1B, NPHS1, SGK2, PITX2, S100A4, and MSX1) were identified from protein-protein interaction (PPI) network which were mostly expressed as down-regulated. …”
Publicado 2023
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489por Freed, William J., Chen, Jia, Bäckman, Cristina M., Schwartz, Catherine M., Vazin, Tandis, Cai, Jingli, Spivak, Charles E., Lupica, Carl R., Rao, Mahendra S., Zeng, Xianmin“…PRINCIPAL FINDINGS: A number of genes known to be involved in the specification of dopaminergic neurons, including MSX1, CDKN1C, Pitx1 and Pitx2, as well as several novel genes not previously associated with dopaminergic differentiation, were expressed. …”
Publicado 2008
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490por Ohta, H, Aoyagi, K, Fukaya, M, Danjoh, I, Ohta, A, Isohata, N, Saeki, N, Taniguchi, H, Sakamoto, H, Shimoda, T, Tani, T, Yoshida, T, Sasaki, H“…Furthermore, we identified two cancer-specific Hh targets, ELK1 and MSX2, which have an essential role in GC cell growth. …”
Publicado 2009
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491por Qi, Hank H., Sarkissian, Madathia, Hu, Gang-Qing, Wang, Zhibin, Bhattacharjee, Arindam, Gordon, D. Benjamin, Gonzales, Michelle, Lan, Fei, Ongusaha, Pat P., Huarte, Maite, Yaghi, Nasser K., Lim, Huijun, Garcia, Benjamin A., Brizuela, Leonardo, Zhao, Keji, Roberts, Thomas M., Shi, Yang“…Lastly, genetic and molecular evidence supports a model whereby PHF8 regulates zebrafish neuronal cell survival and jaw development in part by directly regulating the expression of the homeodomain transcription factor MSX1/MSXB, which functions downstream of multiple signaling and developmental pathways3. …”
Publicado 2010
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492por Nieto-Miguel, Teresa, Calonge, Margarita, de la Mata, Ana, López-Paniagua, Marina, Galindo, Sara, de la Paz, María Fideliz, Corrales, Rosa M.“…This led to the identification of specific molecules, chemokine (C-X-C motif) ligand 12 (CXCL12), islet-1 transcription factor LIM/homeodomain (ISL1), collagen-type II alpha 1 (COL2A), neural cell adhesion molecule 1 (NCAM1), aggrecan (ACAN), forkhead box A2 (FOXA2), Gap junction protein beta 1/connexin 32 (GJB1/Cnx32), and Msh homeobox 1 (MSX1), that could be used to recognize putative corneal epithelial SCs grown in culture and intended for transplantation. …”
Publicado 2011
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493por Chan, Audrey A., Hertsenberg, Andrew J., Funderburgh, Martha L., Mann, Mary M., Du, Yiqin, Davoli, Katherine A., Mich-Basso, Jocelyn Danielle, Yang, Lei, Funderburgh, James L.“…Gene expression, examined by quantitative RT-PCR, found hES cells co-cultured with PA6 cells for 6 days to upregulate expression of neural crest genes including NGFR, SNAI1, NTRK3, SOX9, and MSX1. Isolated NGFR-expressing cells were free of PA6 feeder cells. …”
Publicado 2013
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494“…Furthermore, light stimulation of Arch for only 2 days after amputation restored regenerative capacity to inhibited tails, inducing cell proliferation, tissue innervation, and upregulation of notch1 and msx1, essential genes in two well-known endogenous regenerative pathways. …”
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495por Bidkhori, Gholamreza, Narimani, Zahra, Hosseini Ashtiani, Saman, Moeini, Ali, Nowzari-Dalini, Abbas, Masoudi-Nejad, Ali“…The genes EGFR, PIK3CA, TAF15, XIAP, VAPB, Appl1, Rab5a, ARF4, CLPTM1L, SP4, ZNF124, LPP, FOXP1, SOX18, MSX2, NFE2L2, SMARCC1, TRA2B, CBX3, PRPF6, ATP6V1C1, MYBBP1A, MACF1, GRM2, TBXA2R, PRKAR2A, PTK2, PGF and MYO10 are among the genes that belong to modules 1 and 22. …”
Publicado 2013
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496por Atkinson, Andrew J., Logantha, Sunil Jit R. J., Hao, Guoliang, Yanni, Joseph, Fedorenko, Olga, Sinha, Aditi, Gilbert, Stephen H., Benson, Alan P., Buckley, David L., Anderson, Robert H., Boyett, Mark R., Dobrzynski, Halina“…Using laser microdissection gene expression measured at the mRNA level (using quantitative PCR) and protein level (using immunohistochemistry and Western blotting) showed that the right ring and retroaortic node, like the sinus node and AV node but, unlike ventricular muscle, had statistically significant higher expression of key transcription factors (including Tbx3, Msx2, and Id2) and ion channels (including HCN4, Ca(v)3.1, Ca(v)3.2, K(v)1.5, SK1, K(ir)3.1, and K(ir)3.4) and lower expression of other key ion channels (Na(v)1.5 and K(ir)2.1). …”
Publicado 2013
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497por Randall, Patrick A., Lee, Christie A., Nunes, Eric J., Yohn, Samantha E., Nowak, Victoria, Khan, Bilal, Shah, Priya, Pandit, Saagar, Vemuri, V. Kiran, Makriyannis, Alex, Baqi, Younis, Müller, Christa E., Correa, Merce, Salamone, John D.“…The adenosine A(2A) antagonist MSX-3, the antidepressant and catecholamine uptake inhibitor bupropion, and the MAO-B inhibitor deprenyl, all reversed the impairments induced by tetrabenazine. …”
Publicado 2014
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498“…ALK3 and ALK6 are independently required for the spatially restricted activation of BMP signaling and msx2 upregulation at the neural plate border, whereas in post-gastrula development ALK6 exerts a highly specific, conserved function in neural crest development. …”
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499por Phan, M., Conte, F., Khandelwal, K. D., Ockeloen, C. W., Bartzela, T., Kleefstra, T., van Bokhoven, H., Rubini, M., Zhou, H., Carels, C. E. L.“…Altogether, 84 articles including phenotype and genotype description provided 9 genomic loci and 26 gene candidates underlying the co-occurrence of the two congenital defects: MSX1, PAX9, IRF6, TP63, KMT2D, KDM6A, SATB2, TBX22, TGFα, TGFβ3, TGFβR1, TGFβR2, FGF8, FGFR1, KISS1R, WNT3, WNT5A, CDH1, CHD7, AXIN2, TWIST1, BCOR, OFD1, PTCH1, PITX2, and PVRL1. …”
Publicado 2016
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500por Fraimout, Antoine, Debat, Vincent, Fellous, Simon, Hufbauer, Ruth A., Foucaud, Julien, Pudlo, Pierre, Marin, Jean-Michel, Price, Donald K., Cattel, Julien, Chen, Xiao, Deprá, Marindia, François Duyck, Pierre, Guedot, Christelle, Kenis, Marc, Kimura, Masahito T., Loeb, Gregory, Loiseau, Anne, Martinez-Sañudo, Isabel, Pascual, Marta, Polihronakis Richmond, Maxi, Shearer, Peter, Singh, Nadia, Tamura, Koichiro, Xuéreb, Anne, Zhang, Jinping, Estoup, ArnaudEnlace del recurso
Publicado 2017
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