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501por Cui, Lin, Rashdan, Nabil A., Zhu, Dongxing, Milne, Elspeth M., Ajuh, Paul, Milne, Gillian, Helfrich, Miep H., Lim, Kelvin, Prasad, Sai, Lerman, Daniel A., Vesey, Alex T., Dweck, Marc R., Jenkins, William S., Newby, David E., Farquharson, Colin, Macrae, Vicky E.“…Ca treatment increased the mRNA of the osteogenic markers Msx2, Runx2, and Alpl (p < 0.01). MVs were harvested by ultracentrifugation from VICs cultured with control or calcification media (containing 2.7 mM Ca and 2.5 mM Pi) for 16 hr. …”
Publicado 2017
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502por Chovatiya, Gopal L., Sarate, Rahul M., Sunkara, Raghava R., Gawas, Nilesh P., Kala, Vineet, Waghmare, Sanjeev K.“…Molecular investigation study showed aberrant expression of Sox21, Msx2 and signalling modulators necessary for proper differentiation of inner root sheath (IRS) and hair shaft formation. …”
Publicado 2017
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503por Zhao, Yong-Xin, Yang, Ji, Lv, Feng-Hua, Hu, Xiao-Ju, Xie, Xing-Long, Zhang, Min, Li, Wen-Rong, Liu, Ming-Jun, Wang, Yu-Tao, Li, Jin-Quan, Liu, Yong-Gang, Ren, Yan-Ling, Wang, Feng, Hehua, EEr, Kantanen, Juha, Arjen Lenstra, Johannes, Han, Jian-Lin, Li, Meng-HuaEnlace del recurso
Publicado 2017
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504por Yuvaraj, Jothi Kumar, Corcoran, Jacob A., Andersson, Martin N., Newcomb, Richard D., Anderbrant, Olle, Löfstedt, ChristerEnlace del recurso
Publicado 2017
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505por Eyun, Seong-il, Soh, Ho Young, Posavi, Marijan, Munro, James B., Hughes, Daniel S.T., Murali, Shwetha C., Qu, Jiaxin, Dugan, Shannon, Lee, Sandra L., Chao, Hsu, Dinh, Huyen, Han, Yi, Doddapaneni, HarshaVardhan, Worley, Kim C., Muzny, Donna M., Park, Eun-Ok, Silva, Joana C., Gibbs, Richard A., Richards, Stephen, Lee, Carol EunmiEnlace del recurso
Publicado 2017
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506por Nagel, Stefan, MacLeod, Roderick A. F., Meyer, Corinna, Kaufmann, Maren, Drexler, Hans G.“…Finally, NKL homeobox genes HHEX, HLX, MSX1 and NKX6-3 were expressed in B-cell progenitors and generated a regulatory gene network in cell lines which we propose may provide physiological support for NKL-code formation in early B-cell development. …”
Publicado 2018
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507por Diomede, Francesca, Zini, Nicoletta, Pizzicannella, Jacopo, Merciaro, Ilaria, Pizzicannella, Giuseppe, D’Orazio, Monica, Piattelli, Adriano, Trubiani, Oriana“…By RT-PCR, EBs-hGMSCs expressed specific transcription markers related to the three germ layers as MAP-2, PAX-6 (ectoderm), MSX-1, Flk-1 (mesoderm), GATA-4, and GATA-6 (endoderm). …”
Publicado 2018
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508por Nagel, Stefan, MacLeod, Roderick A.F., Pommerenke, Claudia, Meyer, Corinna, Kaufmann, Maren, Drexler, Hans G.“…Downstream analyses indicated that NKX2-2 inhibits transcription of lymphoid NKL homeobox gene MSX1 and activates expression of basic helix-loop-helix factor NEUROD1 which may disturb B-cell differentiation processes via reported interaction with TCF3/E2A. …”
Publicado 2018
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509por Xu, Junfen, Liu, Habin, Yang, Yanqin, Wang, Xiaohong, Liu, Poching, Li, Yang, Meyers, Craig, Banerjee, Nilam Sanjib, Wang, Hsu-Kun, Cam, Maggie, Lu, Weiguo, Chow, Louise T., Xie, Xing, Zhu, Jun, Zheng, Zhi-Ming“…LY6K (lymphocyte antigen 6 complex locus K), FAM83A (family member with sequence similarity 83), CELSR3, ASF1B, IQGAP3, SEMA3F, CLDN10, MSX1, CXCL5, ASRGL1, ELAVL2, GRB7, KHSRP, NOVA1, PTBP1, and RNASEH2A were identified as novel candidate genes associated with cervical lesion progression and carcinogenesis. …”
Publicado 2019
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510por Paccola Mesquita, Fernanda C., Hochman-Mendez, Camila, Morrissey, Jacquelynn, Sampaio, Luiz C., Taylor, Doris A.“…Spontaneous differentiation into ectoderm (NESTIN, TUBB3, and NEFH), mesoderm (MSX1, BMP4, and T), and endoderm (GATA6, AFP, and SOX17) lineages was detected by RT-PCR with both coating systems. …”
Publicado 2019
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511“…Unexpectedly, Dlx2 overexpression had little impact on the expression level of the pivotal osteogenic transcription factors Runx2, Dlx5, Msx2, and Osterix, but led to upregulation of Alp and Osteocalcin (OCN), both of which play critical roles in promoting osteoblast maturation. …”
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512por Schelski, Nadeshda, Luong, Trang T. D., Lang, Florian, Pieske, Burkert, Voelkl, Jakob, Alesutan, Ioana“…This effect was paralleled by upregulation of the mRNA expression of MSX2 and CBFA1, osteogenic transcription factors, and of tissue-nonspecific alkaline phosphatase (ALPL), an osteogenic enzyme, as markers of increased osteo-/chondrogenic transdifferentiation. …”
Publicado 2019
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513“…RESULTS: Six genes (SLC17A7, MSX2, CDC26, MSLN, CTSZ and DEFA3) identified by univariate, Kaplan-Meier survival and multivariate Cox regression analyses were used to develop the prognostic model. …”
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514“…A locus in chromosome 4p16, adjacent to MSX1 and STX18, has been associated with atrial septal defects (ASD) in multiple European and Chinese cohorts. …”
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515por Rodrigues, Amanda Silva, Teixeira, Ellen Cardoso, Antunes, Leonardo Santos, Nelson-Filho, Paulo, Cunha, Arthur Silva, Levy, Simone Carvalho, de Souza Araújo, Mônica Tirre, de Carvalho Ramos, Alice Gomes, Cruz, Giuseppe Valduga, Omori, Marjorie Ayumi, Matsumoto, Mírian Aiko Nakane, Vieira, Alexandre Rezende, Küchler, Erika Calvano, Marañón-Vásquez, Guido Artemio, Antunes, Lívia Azeredo Alves“…Genomic DNA was extracted from squamous epithelial cells of buccal mucosa and genetic polymorphisms in MSX1 (rs1042484), PAX9 (rs8004560), TGF-α (rs2902345), FGF3 (rs1893047), FGF10 (rs900379), and FGF13 (rs12838463, rs5931572, and rs5974804) were genotyped by polymerase chain reaction using TaqMan chemistry and end-point analysis. …”
Publicado 2020
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516por Jefferson, Wendy N., Padilla-Banks, Elizabeth, Suen, Alisa A., Royer, Lindsey J., Zeldin, Sharon M., Arora, Ripla, Williams, Carmen J.“…Expression of Foxa2, Wnt4, and Sox17, as well as genes important for neonatal uterine differentiation (Wnt7a, Hoxa10, and Msx2), were severely disrupted on PND5 in GEN-exposed mice. …”
Publicado 2020
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517por Churchman, Sarah M, Jones, Elena A, Roshdy, Tarek, Cox, George, Boxall, Sally A, McGonagle, Dennis, Giannoudis, Peter V“…Analysis of FVB-MSCs suggested that their likely origin was bone marrow as only two differences were observed between FVB-MSCs and IC-BM-MSCs (ACVR2A, p = 0.032 and MSX1, p = 0.003). Stromal cells with the phenotype and molecular profile of MSCs were scarcely found in the circulation, supporting the hypothesis that their very rare presence is likely linked to biophysical micro-damage caused by skeletal trauma (here orthopaedic manipulation) rather than specific molecular cues to a circulatory pool of MSCs capable of repair of remote organs or tissues. …”
Publicado 2020
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518por Manokawinchoke, Jeeranan, Sumrejkanchanakij, Piyamas, Boonprakong, Lawan, Pavasant, Prasit, Egusa, Hiroshi, Osathanon, Thanaphum“…Further, shNOTCH2-transduced cells exhibited less alkaline phosphatase enzymatic activity and in vitro mineralization than the shControl cells when exposed to Jagged1. MSX2 and COL1A1 mRNA expression after Jagged1 activation were reduced in shNOTCH2-transduced cells. …”
Publicado 2020
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519por Ibarra‐Arce, Aurora, Almaraz‐Salinas, Manuel, Martínez‐Rosas, Víctor, Ortiz de Zárate‐Alarcón, Gabriela, Flores‐Peña, Laura, Romero‐Valdovinos, Mirza, Olivo‐Díaz, Angélica“…On the other hand, it would be important to include other genes, such as TCF12 (OMIM 600,480), MSX2 (OMIM 123,101), RAB23 (OMIM 606,144), and EFNB1 (OMIM 300,035), to determine their participation in craniosynostosis in the Mexican population.…”
Publicado 2020
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520por Ruff, Katharina L. M., Hollstein, Ronja, Fazaal, Julia, Thieme, Frederic, Gehlen, Jan, Mangold, Elisabeth, Knapp, Michael, Welzenbach, Julia, Ludwig, Kerstin U.“…Analysing the craniofacial TF TFAP2A in human embryonic palatal mesenchyme (HEPM) cells, we identified 2845 TFAP2A ChIP-seq peaks, several of which were located near nsCL/P candidate genes (e.g. MSX1 and SPRY2). Comparison with independent data suggest that 802 of them might be specific to craniofacial development, and genes near these peaks are enriched in processes relevant to nsCL/P. …”
Publicado 2022
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