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41por Vance, Keith W., Woodcock, Dan J., Reid, John E., Bretschneider, Till, Ott, Sascha, Koentges, Georgy“…In this study, we used live cell imaging of transfected reporters combined with a mathematical modelling and statistical inference scheme to quantify the function of conserved Msx1 CRMs and promoters in modulating single-cell real-time transcription rates in C2C12 mouse myoblasts. …”
Publicado 2015
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42por Li, Fei-Feng, Han, Ying, Shi, Shuai, Li, Xia, Zhu, Xi-Dong, Zhou, Jing, Shao, Qing-Liang, Li, Xue-Qi, Liu, Shu-Lin“…The aim of this work was to evaluate variations in MSX1 and MSX2 for their possible associations with CHD. …”
Publicado 2015
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43“…RESULTS: Refined mapping of the spine length QTL shows that it lies near the MSX2A transcription factor gene. MSX2A is expressed in developing spines. …”
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44por Kwon, Duk-Hwa, Choe, Nakwon, Shin, Sera, Ryu, Juhee, Kim, Nacksung, Eom, Gwang Hyeon, Nam, Kwang-Il, Kim, Hyung Seok, Ahn, Youngkeun, Kim, Young-Kook, Park, Woo Jin, Mendrysa, Susan M., Kook, Hyun“…Msx1 and Msx2 potentiated vascular calcification in cellular and mouse models in an MDM2-dependent manner. …”
Publicado 2021
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45por Kwon, Hyuk-Jae Edward“…METHODS/STUDY POPULATION: We used three different genetically engineered mouse lines: Msx1 ^’/ ^’, Dkk2 ^’/ ^’, and Sostdc1 ^’/ ^’ mice. …”
Publicado 2021
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46por Song, Yupu, Liu, Chang, Zhou, Yuxuan, Lin, Guangyu, Xu, Chenguang, Msuthwana, Petunia, Wang, Sihui, Ma, Jingyun, Zhuang, Fangming, Fu, Xianou, Wang, Yudong, Liu, Tuoya, Liu, Qianyan, Wang, Jingbo, Sui, Yujian, Sun, Yongfeng“…The pEGFP-N1-Msx2 overexpression vector and si-Msx2 siRNA vector were constructed to transfect goose embryo dermal fibroblasts. …”
Publicado 2022
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47“…RESULTS: Vertebrate Msx sequences sort into distinct Msx1, Msx2 and Msx3 clades. …”
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48por Katerji, Suhair, Vanmuylder, Nathalie, Svoboda, Michal, Rooze, Marcel, Louryan, Stéphane“…Semi-quantitative PCR analysis demonstrated that Msx1 and Dlx1 are expressed differently between Dumbo and Wistar rats, indicating that their low expression may underly the Dumbo phenotype.…”
Publicado 2009
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49“…Interaction of Msx1 with G9a is mediated via the homeodomain and is required for transcriptional repression and regulation of cellular differentiation, as well as enrichment of the H3K9me2 mark in proximity to Msx1 binding sites on repressed target genes in myoblast cells as well as the developing limb. …”
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50“…Here, we demonstrate that elevated expression of FOXC1 can increase endogenous Msx2 mRNA levels. Chromatin immunoprecipitation experiments reveal that FOXC1 occupies a conserved element in the MSX2 promoter. …”
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51“…The purpose of this study was to investigate the contribution of MSX1 gene to the risk of nonsyndromic cleft lip with or without cleft palate (NS-CL ± P) in the Korean population. …”
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52por Castaneda, Beatriz, Simon, Yohann, Ferbus, Didier, Robert, Benoit, Chesneau, Julie, Mueller, Christopher, Berdal, Ariane, Lézot, Frédéric“…The MSX2 homeoprotein is implicated in all aspects of craniofacial skeletal development. …”
Publicado 2013
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53por Reddy, Naveen Admala, Adusumilli, Gopinath, Devanna, Raghu, Mayur, Rohra G, Pichai, Saravanan, Arujnan, Sharmila“…AIM OF THE STUDY: The aim of this study was to test whether MSX1 671 T > C gene variant was involved in etiology of non-syndromic tooth agenesis in Raichur patients. …”
Publicado 2013
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54“…AIM: To search for mutations on the MSX1 gene and to present a genetic basis for non-syndromic tooth agenesis in conjunction with dental anomalies in a Turkish population. …”
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55por Nagel, Stefan, Pommerenke, Claudia, Meyer, Corinna, Kaufmann, Maren, MacLeod, Roderick A.F., Drexler, Hans G.“…NKL homeobox gene MSX1 is physiologically expressed in lymphoid progenitors and subsequently downregulated in developing T- and B-cells. …”
Publicado 2017
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56por van Nistelrooij, A. M. J., van Marion, R., van Ijcken, W. F. J., de Klein, A., Wagner, A., Biermann, K., Spaander, M. C. W., van Lanschot, J. J. B., Dinjens, W. N. M., Wijnhoven, B. P. L.“…A germline variant in MSX1 was identified in a Dutch family with clustering of Barrett’s esophagus and esophageal adenocarcinoma. …”
Publicado 2017
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57por Bonczek, Ondřej, Bielik, Peter, Krejčí, Přemysl, Zeman, Tomáš, Izakovičová-Hollá, Lýdie, Šoukalová, Jana, Vaněk, Jiří, Gerguri, Tereza, Balcar, Vladimir J., Šerý, Omar“…Mutation g.8177G>T leads to a stop codon (p.E204X) and premature termination of Msx1 protein translation. Based on previous in vitro experiments on mutation disrupting function of Msx1 homeodomain, we assume that the heterozygous g.8177G>T nonsense mutation affects the amount and function of Msx1 protein and leads to tooth agenesis.…”
Publicado 2018
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58por Horazna, Monika, Janeckova, Lucie, Svec, Jiri, Babosova, Olga, Hrckulak, Dusan, Vojtechova, Martina, Galuskova, Katerina, Sloncova, Eva, Kolar, Michal, Strnad, Hynek, Korinek, Vladimir“…The gene encoding transcriptional factor msh homeobox 1 (Msx1) displayed robust upregulation upon Apc inactivation. …”
Publicado 2019
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59por West, James, Rathinasabapathy, Anandharajan, Chen, Xinping, Shay, Sheila, Gladson, Shanti, Talati, Megha“…Under normoxic conditions, compared to controls, MSX1(OE) mice demonstrated a 30-fold and 2-fold increase in lung Msx1 mRNA and protein expression, respectively. …”
Publicado 2021
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60Family and case–control genetic study of MSX1 polymorphisms in peg-shaped teeth Jordanian populationpor Alkhatib, Rami, Hawamdeh, Razan, Al-Eitan, Laith, Abdo, Nour, Obeidat, Fadi, Al-Bataineh, Mohamed, Aman, Hatem“…Then, polymerase chain reaction technique (PCR) was conducted using specific primers for the axons of the MSX1. Moreover, DNA sequencing genotyping method analysis of SNPs was used to detect specified SNPs in the MSX1 linked with peg-shaped teeth. …”
Publicado 2022
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