“…SRD and TLSRD significantly discriminated between pT3 or pT4 PanNEN versus pT1 or pT2, as well as 18F-FDG MTV and TLG. 68Ga-DOTATOC SUVmax was able to significantly predict the presence of distant metastases with a threshold of 51.27 (sensitivity and specificity of 85.7 and 68.1%, respectively). 18F-FDG MTV and TLG were predictors of angioinvasion. …”
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“…On multivariate analysis, F-18 FDG MTV > 21.3 cm(3) was the most significant predictor (p < 0.001). …”
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“…In multivariable analysis, aortic FDG uptake and MTV(≥2.5) values were independently associated (β = 0.425; 95% CI: 0.189 to 0.662; p = 0.001; R(2) = 0.208), as were aortic FDG uptake and MTV(≥41%) (β = 0.407; 95% CI: 0.167 to 0.649, p = 0.001; R(2) = 0.191). …”
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“…However, the roles of PET/CT metabolic parameters, such as metabolic tumor volume (MTV) and total lesion glycolysis (TLG), remain unclear in this setting. …”
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“…Patients’ cTN stage, metabolic tumor volume (MTV) parameters, and clinical data were collected. …”
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“…Patients underwent physiologic appraisal at 3 months with (13)C-spirulina-based gastric emptying breath test to determine time to half emptying (T50), as well as maximum tolerated volume (MTV) of a standard nutrient drink test. Changes in T50 and MTV at 3 months were compared with percent total body weight loss (%TBWL) at 3 and 6 months using best-fit linear regression. …”
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“…Logistic regression demonstrated that MTV (metabolic tumor volume) and TLG (total lesion glycolysis) computation according to V2.5 and Vliver significantly correlated to response to treatment (p = 0.01 and 0.04 for MTV and 0.03 and 0.04 for TLG, respectively). …”
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“…Hazard ratio (HR) was used as a pooled statistic to assess the association of SUVmax, MTV, and TLG with PFS, EFS, and OS in neuroblastoma patients. …”
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“…The following (18)F-FDG PET parameters were evaluated: maximum standardized uptake value (SUV(max)), mean standardized uptake value (SUV(mean)), peak standardized uptake value (SUV(peak)), metabolic tumour volumes (MTVs) (MTV(30)–MTV(70), which were calculated as the tumour volume with 30%, 40%, 50%, 60% and 70% of the SUV(max) as the threshold, respectively) and total lesion glycolysis (TLG) (TLG(30)–TLG(70), which were determined by the product of each MTV and the corresponding SUV(mean) within that MTV). …”
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“…The maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) were obtained with the corresponding baseline values (SUV0, MTV0, and TLG0, respectively) and interim PET images (SUV1, MTV1, and TLG1, respectively). …”
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“…Maximum standardized uptake value, metabolic tumor volume (MTV), total lesion glycolysis (TLG), and minimum apparent diffusion coefficient (ADC(min)) values of primary tumors were obtained from PET/MRI. …”
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“…The usage of Vβ11 makes this TcR reactive to Class II IE molecules and an endogenous ligand recently identified as a product of the endogenous mammary tumour viruses (Mtv) 8, 9, and 11 (Dyson et al., 1991). Here we report the development of F5 transgenic T cells and their function in mice of the appropriate MHC (C57BL/10 H-2(b), IE(-)) or in mice expressing Class II MHC IE (e.g., CBA/Ca H-2(k) and BALB/c H-2(d)) and the endogenous Mtv ligands. …”
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“…Metabolic tumor volume (MTV) was measured with the marginal threshold of normal liver mean standard uptake value (SUVmean) plus 3 standard deviations (SD). …”
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“…RESULTS: There were statistically significant differences between high-grade and low-grade PGISL in terms of SUV(max), SUV(mean), MTV, TLG, recurrence, mortality, DFS and OS. None of the potential risk factors (sex, age, site, SUV(max), SUV(mean), MTV, TLG) for recurrence and metastasis in high grade PGISL was identified as a risk factor on univariate and multivariate Cox regression analysis. …”
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“…RESULTS: The MDC was respectively 105.7ms, 2.77%, 0.37% and 4.08% for T(1), MTR, MT(sat) and MTV when quantified over all WM, while the standard-deviation across subjects was 70.5ms, 1.34%, 0.20% and 2.44%. …”
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“…The results demonstrated that 6 h of mechanical ventilation at low tidal volume (LTV; 6 ml/kg) or moderate tidal volume (MTV; 12 ml/kg) induced lung injury in sensitive A/J mice. …”
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“…Results of ROC analysis showed that mean TBR had the highest AUC in our cohort (0.66 95%CI [0.41; 0.91]) with a cut-off value of 2.2. Specificity of MTV and TLG was 100% (cut-off values: MTV 9.6 ml, TLG 22.9 g) and their sensitivity was 30 and 40%, respectively. …”
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“…Two features including stage and a MTV plus penumbra texture feature were selected by LASSO. …”
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“…The optimal thresholds of MTV and TLG were 15.1 cm(3) and 47.3 cm(3), respectively. …”
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