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  1. 281
    “…Matrix-induced autologous chondrocyte implantation (MACI) was applied to another group in two sessions, and the last group was left untreated. …”
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    In vivo cartilage tissue engineering
  2. 282
    “…These data reassure in that the MACI procedure provides a suitable engineered tissue for cartilage repair, in line with the clinical evidences emerging in the literature.…”
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    Membrane-seeded autologous chondrocytes: cell viability and characterization at surgery
  3. 283
    “…To enhance the MACI therapy efficiency, we have developed a strategy for chondrocyte redifferentiation, and demonstrated its feasibility in the equine model. …”
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    RNA Interference and BMP-2 Stimulation Allows Equine Chondrocytes Redifferentiation in 3D-Hypoxia Cell Culture Model: Application for Matrix-Induced Autologous Chondrocyte Implantation
  4. 284
    “…The number of studies reporting OAT was 8 (27.6%), ACI was 6 (20.7%), MACI was 7 (24.1%), microfracture was 5 (17.2%), osteochondral allograft was 4 (13.8%), and one study (3.4%) reported on PRP and PBSC. …”
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    Sporting participation following the operative management of chondral defects of the knee at mid-term follow up: a systematic review and meta-analysis
  5. 285
    “…OBJECTIVE: To assess the safety and efficacy of accelerated compared with traditional postoperative weightbearing (WB) rehabilitation following matrix-induced autologous chondrocyte implantation (MACI) of the knee, using MRI. METHODS: A randomized controlled study design was used to assess MRI-based outcomes of MACI grafts in 70 patients (45 men, 25 women) who underwent MACI to the medial or lateral femoral condyle, in combination with either traditional or accelerated approaches to postoperative WB rehabilitation. …”
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    Radiological Assessment of Accelerated versus Traditional Approaches to Postoperative Rehabilitation following Matrix-Induced Autologous Chondrocyte Implantation
  6. 286
    “…In particular, we identify a set of microsyntenies associated with cephalopod innovations (MACIs) broadly enriched in cephalopod nervous system expression. …”
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    Emergence of novel cephalopod gene regulation and expression through large-scale genome reorganization
  7. 287
    “…In the hip, arthroscopic treatment of cartilage defects is technically challenging, especially the autologous chondrocyte implantation/matrix-associated autologous chondrocyte implantation (ACI/MACI) procedures. The purpose of this prospective study was to introduce two injectable MACI products with self-adherent properties. …”
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    Arthroscopic autologous chondrocyte implantation in the hip for the treatment of full-thickness cartilage defects: A case series of 29 patients and review of the literature
  8. 288
    “…Data on patient, tumor, and recurrence characteristics were collected, and each patient was given a MACIS score. Results. A total of 31 patients were identified (11 male, 20 female; 16–83 years). …”
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    Prognostic Factors in Patients with Multiple Recurrences of Well-Differentiated Thyroid Carcinoma
  9. 289
    por De Ferrari, Luna, Mitchell, John BO
    Publicado 2014
    “…RESULTS: In this study, we evaluate whether sequence identity, InterPro or Catalytic Site Atlas sequence signatures provide enough information for bulk prediction of enzyme mechanism. By splitting MACiE (Mechanism, Annotation and Classification in Enzymes database) mechanism labels to a finer granularity, which includes the role of the protein chain in the overall enzyme complex, the method can predict at 96% accuracy (and 96% micro-averaged precision, 99.9% macro-averaged recall) the MACiE mechanism definitions of 248 proteins available in the MACiE, EzCatDb (Database of Enzyme Catalytic Mechanisms) and SFLD (Structure Function Linkage Database) databases using an off-the-shelf K-Nearest Neighbours multi-label algorithm. …”
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    From sequence to enzyme mechanism using multi-label machine learning
  10. 290
    “…However, there is a lack of knowledge about the potential use of Facebook as a means of communication for persons with potential Mild Acquired Cognitive Impairment (MACI), a non-progressive mild cognitive impairment after an acquired brain injury. …”
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    Facebook as communication support for persons with potential mild acquired cognitive impairment: A content and social network analysis study
  11. 291
    “…Restoring strength deficits after MACI is important for achieving optimal outcomes.…”
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    Association Between Isokinetic Knee Strength and Perceived Function and Patient Satisfaction With Sports and Recreational Ability After Matrix-Induced Autologous Chondrocyte Implantation
  12. 292
    por Evan
    Publicado 2023
    “…Nowadays, there are a lot of modalities for cartilage repair such as microfracture, mosaicplasty, ACI, MACI, platelet-rich plasma, bone marrow aspirate concentrate, orthokine or interleukin receptor antagonist and Matrix metalloproteinases (MMPs) inhibitor.…”
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    The Biologic Approach for Managing Cartilage Injury: Where are We Now™
  13. 293
    “…The MACI method with O2PLS is a powerful tool with great potential for visualising and comparing dynamics between movements. …”
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    Dynamic ultrasound imaging—A multivariate approach for the analysis and comparison of time-dependent musculoskeletal movements
  14. 294
    “…Most of the Matrix Autologous Chondrocyte Implantation (MACI) cases reported in literature do not deal with rheumatoid knees and do not have a long clinical-histologic follow-up. …”
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    Chondral tissue engineering of the reumatoid knee with collagen matrix autologous chondrocytes implant
  15. 295
    “…Bone marrow stimulation (i.e., microfracture) remains a standard technique for cartilage repair promotion, despite incurring the adverse generation of fibrocartilagenous scar tissue, while matrix-induced autologous chondrocyte implantation (MACI) and alternative autologous cell-based approaches may partly circumvent this effect. …”
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    Development of Standardized Fetal Progenitor Cell Therapy for Cartilage Regenerative Medicine: Industrial Transposition and Preliminary Safety in Xenogeneic Transplantation
  16. 296
    “…OBJECTIVE: To determine the safety and efficacy of “accelerated” postoperative load-bearing rehabilitation following matrix-induced autologous chondrocyte implantation (MACI). DESIGN: A randomized controlled study design was used to investigate clinical outcomes in 70 patients following MACI, in conjunction with either accelerated or traditional approaches to postoperative weight-bearing (WB) rehabilitation. …”
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    A Prospective, Randomized Comparison of Traditional and Accelerated Approaches to Postoperative Rehabilitation following Autologous Chondrocyte Implantation: 2-Year Clinical Outcomes
  17. 297
    “…In lesions larger than 4 cm(2), MACI was the most commonly advocated procedure (67%). …”
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    Cartilage repair strategies in the knee: A survey of Turkish surgeons
  18. 298
    “…Therefore, much attention has been focused on surgical restoration with hyaline cartilage (type II collagen), based on chondrocyte transplantation and matrix-assisted autologous chondrocyte implantation (MACI). Limited graft availability, staged procedures (MACI), and high treatment costs are limitations of these techniques. …”
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    Reconstruction of Large Osteochondral Lesions in the Knee: Focus on Fixation Techniques
  19. 299
    por Benthien, J. P., Behrens, P.
    Publicado 2010
    “…Options for the treatment of cartilage defects include chondral resurfacing with abrasion, debridement, autologous chondrocyte transplantation (ACT), matrix-induced chondrocyte transplantation (MACI), or osteochondral autologous transplantation (OATS). …”
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    Autologous Matrix-Induced Chondrogenesis (AMIC): Combining Microfracturing and a Collagen I/III Matrix for Articular Cartilage Resurfacing
  20. 300
    “…OBJECTIVE: Matrix-associated autologous chondrocyte implantation (MACI) achieves good clinical efficacy in young patients with focal cartilage injury; however, phenotypic de-differentiation of chondrocytes cultured in monolayer and the treatment of older OA patients are still challenges in the field of cartilage tissue engineering. …”
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    Effects of cell phenotype and seeding density on the chondrogenic capacity of human osteoarthritic chondrocytes in type I collagen scaffolds
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