Ceftolozane-Tazobactam for the Treatment of Multidrug-Resistant Pseudomonas aeruginosa Infections: A Multicenter Study

por Gallagher, Jason C, Satlin, Michael J, Elabor, Abdulrahman, Saraiya, Nidhi, McCreary, Erin K, Molnar, Esther, El-Beyrouty, Claudine, Jones, Bruce M, Dixit, Deepali, Heil, Emily L, Claeys, Kimberly C, Hiles, Jon, Vyas, Nikunj M, Bland, Christopher M, Suh, Jin, Biason, Kenneth, McCoy, Dorothy, King, Madeline A, Richards, Lynette, Harrington, Nicole, Guo, Yi, Chaudhry, Saira, Lu, Xiaoning, Yu, Daohai
Publicado 2018

Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma

por Kryza, Thomas, Khan, Tashbib, Puttick, Simon, Li, Chao, Sokolowski, Kamil A, Tse, Brian WC, Cuda, Tahleesa, Lyons, Nicholas, Gough, Madeline, Yin, Julia, Parkin, Ashleigh, Deryugina, Elena I, Quigley, James P., Law, Ruby H. P., Whisstock, James C., Riddell, Andrew D., Barbour, Andrew P., Wyld, David K., Thomas, Paul A., Rose, Stephen, Snell, Cameron E., Pajic, Marina, He, Yaowu, Hooper, John D.
Publicado 2020

Disruption of Glycogen Utilization Markedly Improves the Efficacy of Carboplatin against Preclinical Models of Clear Cell Ovarian Carcinoma

por Khan, Tashbib, He, Yaowu, Kryza, Thomas, Harrington, Brittney S., Gunter, Jennifer H., Sullivan, Mitchell A., Cuda, Tahleesa, Rogers, Rebecca, Davies, Claire M., Broomfield, Amy, Gough, Madeline, Wu, Andy C., McGann, Thomas, Weroha, S. John, Haluska, Paul, Forbes, Josephine M., Armes, Jane E., Barry, Sinead C., Coward, Jermaine I., Jagasia, Nisha, Chetty, Naven, Snell, Cameron E., Lourie, Rohan, Perrin, Lewis C., Hooper, John D.
Publicado 2020

Concanamycin A counteracts HIV-1 Nef to enhance immune clearance of infected primary cells by cytotoxic T lymphocytes

por Painter, Mark M., Zimmerman, Gretchen E., Merlino, Madeline S., Robertson, Andrew W., Terry, Valeri H., Ren, Xuefeng, McLeod, Megan R., Gomez-Rodriguez, Lyanne, Garcia, Kirsten A., Leonard, Jolie A., Leopold, Kay E., Neevel, Andrew J., Lubow, Jay, Olson, Eli, Piechocka-Trocha, Alicja, Collins, David R., Tripathi, Ashootosh, Raghavan, Malini, Walker, Bruce D., Hurley, James H., Sherman, David H., Collins, Kathleen L.
Publicado 2020

Disease-specific ACMG/AMP guidelines improve sequence variant interpretation for hearing loss

por Patel, Mayher J, DiStefano, Marina T, Oza, Andrea M, Hughes, Madeline Y, Wilcox, Emma H, Hemphill, Sarah E, Cushman, Brandon J, Grant, Andrew R, Siegert, Rebecca K, Shen, Jun, Chapin, Alex, Boczek, Nicole J, Schimmenti, Lisa A, Nara, Kiyomitsu, Kenna, Margaret, Azaiez, Hela, Booth, Kevin T, Avraham, Karen B, Kremer, Hannie, Griffith, Andrew J., Rehm, Heidi L, Amr, Sami S, Tayoun, Ahmad N Abou
Publicado 2021

An international survey examining the impact of the COVID-19 pandemic on telehealth use among mental health professionals

por Montoya, Madeline I., Kogan, Cary S., Rebello, Tahilia J., Sadowska, Karolina, Garcia-Pacheco, José A., Khoury, Brigitte, Kulygina, Maya, Matsumoto, Chihiro, Robles, Rebeca, Huang, Jingjing, Andrews, Howard F., Ayuso-Mateos, José Luis, Denny, Keith, Gaebel, Wolfgang, Gureje, Oye, Kanba, Shigenobu, Maré, Karen, Medina-Mora, María Elena, Pike, Kathleen M., Roberts, Michael C., Sharan, Pratap, Stein, Dan J., Scott Stroup, T., Zhao, Min, Reed, Geoffrey M.
Publicado 2022

Genomics4RD: An integrated platform to share Canadian deep‐phenotype and multiomic data for international rare disease gene discovery

por Driver, Hannah G., Hartley, Taila, Price, E. Magda, Turinsky, Andrei L., Buske, Orion J., Osmond, Matthew, Ramani, Arun K., Kirby, Emily, Kernohan, Kristin D., Couse, Madeline, Elrick, Hillary, Lu, Kevin, Mashouri, Pouria, Mohan, Aarthi, So, Delvin, Klamann, Conor, Le, Hannah G. B. H., Herscovich, Andrea, Marshall, Christian R., Statia, Andrew, Canada Consortium, Care4Rare, Knoppers, Bartha M., Brudno, Michael, Boycott, Kym M.
Publicado 2022

Clinical Outcomes of Eravacycline in Patients Treated Predominately for Carbapenem-Resistant Acinetobacter baumannii

por Alosaimy, Sara, Morrisette, Taylor, Lagnf, Abdalhamid M., Rojas, Leonor M., King, Madeline A., Pullinger, Benjamin M., Hobbs, Athena L. V., Perkins, Nicholson B., Veve, Michael P., Bouchard, Jeannette, Gore, Tristan, Jones, Bruce, Truong, James, Andrade, Justin, Huang, Glen, Cosimi, Reese, Kang-Birken, S. Lena, Molina, Kyle C., Biagi, Mark, Pierce, Michael, Scipione, Marco R., Zhao, Jing J., Davis, Susan L., Rybak, Michael J.
Publicado 2022

Comparison of real-world treatment outcomes of systemic immunomodulating therapy in atopic dermatitis patients with dark and light skin types

por Bosma, Angela L., Ouwerkerk, Wouter, Heidema, Madeline J., Prieto-Merino, David, Ardern-Jones, Michael R., Beattie, Paula, Brown, Sara J., Ingram, John R., Irvine, Alan D., Ogg, Graham, Patel, Prakash, Reynolds, Nick J., Hearn, R.M. Ross, Wan, Mandy, Warren, Richard B., Woolf, Richard T., Hyseni, Ariënna M., Gerbens, Louise A.A., Spuls, Phyllis I., Flohr, Carsten, Middelkamp-Hup, Maritza A.
Publicado 2022

Modulation of myeloid and T cells in vivo by Bruton’s tyrosine kinase inhibitor ibrutinib in patients with metastatic pancreatic ductal adenocarcinoma

por Sinha, Meenal, Betts, Courtney, Zhang, Li, Griffith, Madeline J, Solman, Isabelle, Chen, Brandon, Liu, Eric, Tamaki, Whitney, Stultz, Jacob, Marquez, Jaqueline, Sivagnanam, Shamilene, Cheung, Alexander, Pener, Denise, Fahlman, Anne, Taber, Erin, Lerner, Kimberly, Crocker, Matthew, Todd, Kendra, Rajagopalan, Brindha, Ware, Clarisha, Bridge, Mark, Vo, Johnson, Dragomanovich, Hannah, Sudduth-Klinger, Julie, Vaccaro, Gina, Lopez, Charles D, Tempero, Margaret, Coussens, Lisa M, Fong, Lawrence
Publicado 2023

Sulfonylpiperazine compounds prevent Plasmodium falciparum invasion of red blood cells through interference with actin-1/profilin dynamics

por Dans, Madeline G., Piirainen, Henni, Nguyen, William, Khurana, Sachin, Mehra, Somya, Razook, Zahra, Geoghegan, Niall D., Dawson, Aurelie T., Das, Sujaan, Parkyn Schneider, Molly, Jonsdottir, Thorey K., Gabriela, Mikha, Gancheva, Maria R., Tonkin, Christopher J., Mollard, Vanessa, Goodman, Christopher Dean, McFadden, Geoffrey I., Wilson, Danny W., Rogers, Kelly L., Barry, Alyssa E., Crabb, Brendan S., de Koning-Ward, Tania F., Sleebs, Brad E., Kursula, Inari, Gilson, Paul R.
Publicado 2023

Increased tryptophan, but not increased glucose metabolism, predict resistance of pembrolizumab in stage III/IV melanoma

por Oldan, Jorge D., Giglio, Benjamin C., Smith, Eric, Zhao, Weiling, Bouchard, Deeanna M., Ivanovic, Marija, Lee, Yueh Z., Collichio, Frances A., Meyers, Michael O., Wallack, Diana E., Abernethy-Leinwand, Amber, Long, Patricia K., Trembath, Dimitri G., Googe, Paul B., Kowalski, Madeline H., Ivanova, Anastasia, Ezzell, Jennifer A., Nikolaishvili-Feinberg, Nana, Thomas, Nancy E., Wong, Terence Z., Ollila, David W., Li, Zibo, Moschos, Stergios J.
Publicado 2023

Health system-scale language models are all-purpose prediction engines

por Jiang, Lavender Yao, Liu, Xujin Chris, Nejatian, Nima Pour, Nasir-Moin, Mustafa, Wang, Duo, Abidin, Anas, Eaton, Kevin, Riina, Howard Antony, Laufer, Ilya, Punjabi, Paawan, Miceli, Madeline, Kim, Nora C., Orillac, Cordelia, Schnurman, Zane, Livia, Christopher, Weiss, Hannah, Kurland, David, Neifert, Sean, Dastagirzada, Yosef, Kondziolka, Douglas, Cheung, Alexander T. M., Yang, Grace, Cao, Ming, Flores, Mona, Costa, Anthony B., Aphinyanaphongs, Yindalon, Cho, Kyunghyun, Oermann, Eric Karl
Publicado 2023

ISSCR standards for the use of human stem cells in basic research

por Ludwig, Tenneille E., Andrews, Peter W., Barbaric, Ivana, Benvenisty, Nissim, Bhattacharyya, Anita, Crook, Jeremy M., Daheron, Laurence M., Draper, Jonathan S., Healy, Lyn E., Huch, Meritxell, Inamdar, Maneesha S., Jensen, Kim B., Kurtz, Andreas, Lancaster, Madeline A., Liberali, Prisca, Lutolf, Matthias P., Mummery, Christine L., Pera, Martin F., Sato, Yoji, Shimasaki, Noriko, Smith, Austin G., Song, Jihwan, Spits, Claudia, Stacey, Glyn, Wells, Christine A., Zhao, Tongbiao, Mosher, Jack T.
Publicado 2023

Neoantigen-specific CD4(+) tumor-infiltrating lymphocytes are potent effectors identified within adoptive cell therapy products for metastatic melanoma patients

por Hall, MacLean S., Teer, Jamie K., Yu, Xiaoqing, Branthoover, Holly, Snedal, Sebastian, Rodriguez-Valentin, Madeline, Nagle, Luz, Scott, Ellen, Schachner, Ben, Innamarato, Patrick, Hall, Amy M., Blauvelt, Jamie, Rich, Carolyn J., Richards, Allison D., Ceccarelli, Jake, Langer, TJ, Yoder, Sean J., Beatty, Matthew S., Cox, Cheryl A., Messina, Jane L., Abate-Daga, Daniel, Mule, James J., Mullinax, John E., Sarnaik, Amod A., Pilon-Thomas, Shari
Publicado 2023

AHI1 is required for outer segment development and is a modifier for retinal degeneration in nephronophthisis

por Louie, Carrie M, Caridi, Gianluca, Lopes, Vanda S, Brancati, Francesco, Kispert, Andreas, Lancaster, Madeline A, Schlossman, Andrew M, Otto, Edgar A, Leitges, Michael, Groene, Hermann-Josef, Lopez, Irma, Gudiseva, Harini V, O’Toole, John F, Vallespin, Elena, Ayyagari, Radha, Ayuso, Carmen, Cremers, Frans P, den Hollander, Anneke I, Koenekoop, Robert K, Dallapiccola, Bruno, Ghiggeri, Gian Marco, Hildebrandt, Friedhelm, Valente, Enza Maria, Williams, David S, Gleeson, Joseph G
Publicado 2010

Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders

por Brennand, Kristen J., Marchetto, M. Carol, Benvenisty, Nissim, Brüstle, Oliver, Ebert, Allison, Izpisua Belmonte, Juan Carlos, Kaykas, Ajamete, Lancaster, Madeline A., Livesey, Frederick J., McConnell, Michael J., McKay, Ronald D., Morrow, Eric M., Muotri, Alysson R., Panchision, David M., Rubin, Lee L., Sawa, Akira, Soldner, Frank, Song, Hongjun, Studer, Lorenz, Temple, Sally, Vaccarino, Flora M., Wu, Jun, Vanderhaeghen, Pierre, Gage, Fred H., Jaenisch, Rudolf
Publicado 2015

The Role of Inflammation after Surgery for Elders (RISE) study: Study design, procedures, and cohort profile

por Hshieh, Tammy T., Vasunilashorn, Sarinnapha M., D'Aquila, Madeline L., Arnold, Steven E., Dickerson, Bradford C., Fong, Tamara G., Jones, Richard N., Marcantonio, Edward R., Schmitt, Eva M., Xu, Guoquan, Gou, Yun, Chen, Fan, Kunze, Lisa J., Vlassakov, Kamen V., Abdeen, Ayesha R., Lange, Jeffrey K., Earp, Brandon E., Touroutoglou, Alexandra, Carlyle, Becky C., Kivisakk-Webb, Pia, Travison, Thomas G., Dillon, Simon T., Libermann, Towia A., Inouye, Sharon K.
Publicado 2019

Unbiased Metagenomic Sequencing for Pediatric Meningitis in Bangladesh Reveals Neuroinvasive Chikungunya Virus Outbreak and Other Unrealized Pathogens

por Saha, Senjuti, Ramesh, Akshaya, Kalantar, Katrina, Malaker, Roly, Hasanuzzaman, Md, Khan, Lillian M., Mayday, Madeline Y., Sajib, M. S. I., Li, Lucy M., Langelier, Charles, Rahman, Hafizur, Crawford, Emily D., Tato, Cristina M., Islam, Maksuda, Juan, Yun-Fang, de Bourcy, Charles, Dimitrov, Boris, Wang, James, Tang, Jennifer, Sheu, Jonathan, Egger, Rebecca, De Carvalho, Tiago Rodrigues, Wilson, Michael R., Saha, Samir K., DeRisi, Joseph L.
Publicado 2019

Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway

por LaMonte, Gregory M., Rocamora, Frances, Marapana, Danushka S., Gnädig, Nina F., Ottilie, Sabine, Luth, Madeline R., Worgall, Tilla S., Goldgof, Gregory M., Mohunlal, Roxanne, Santha Kumar, T. R., Thompson, Jennifer K., Vigil, Edgar, Yang, Jennifer, Hutson, Dylan, Johnson, Trevor, Huang, Jianbo, Williams, Roy M., Zou, Bing Yu, Cheung, Andrea L., Kumar, Prianka, Egan, Timothy J., Lee, Marcus C. S., Siegel, Dionicio, Cowman, Alan F., Fidock, David A., Winzeler, Elizabeth A.
Publicado 2020