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25221por Love, R. Rebecca, Pombi, Marco, Guelbeogo, Moussa W., Campbell, Nathan R., Stephens, Melissa T., Dabire, Roch K., Costantini, Carlo, della Torre, Alessandra, Besansky, Nora J.“…Chromosomal inversion polymorphisms have special importance in the Anopheles gambiae complex of malaria vector mosquitoes, due to their role in local adaptation and range expansion. …”
Publicado 2020
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25222por Fontana, José Domingos, Ferreira, Rafael Lopes, Zuccolotto, Tatiana, de Borba Dallagassa, Cibelle, Wielewski, Leonardo Pellizzari, Chalcoski, Barbara Maria Santano, da Silva, Mario Antonio Navarro, Richardi, Vinicius Sobrinho, Golart, Jonas, de Melo Rodovalho, Cynara“…Any bioassay to test new chemically synthesized larvicides or phytolarvicides against Culicidae and more harmful mosquito species, such as Aedes aegypti and Aedes albopictus, which specifically transmit dengue, yellow fever, chikungunya viral fevers as well as Zika virus, or Anopheles gambiae, a vector for malaria and philariasis, requires thousands of well-developed larvae, preferably at the fourth instar stage. …”
Publicado 2020
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25223por De Niz, Mariana, Kehrer, Jessica, Brancucci, Nicolas M. B., Moalli, Federica, Reynaud, Emmanuel G., Stein, Jens V., Frischknecht, Friedrich“…Malaria is a life-threatening disease, caused by Apicomplexan parasites of the Plasmodium genus. …”
Publicado 2020
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25224“…The proteome of the malaria parasite Plasmodium falciparum is notable for the pervasive occurrence of homopeptides or low-complexity regions (i.e., regions that are made from a small subset of amino-acid residue types). …”
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25225“…In the folk medicine of Ethiopia, Aloe megalacantha is used for the treatment of wound, dandruff, malaria, diabetes, impotence, colon cleansing, amoeba, ascariasis, abdominal pain, urine retention, snake bite, and evil eye. …”
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25226por SOBATI, Hossein“…The most prevalent infections in humans were Blastocystis hominis (8.6%), followed by Giardia lamblia (8.2%), and Entamoeba coli (6.8%); and the least prevalent infection was Enterobius vermicularis (<0.2%). Malaria agents and Leishmania were not observed in blood samples. …”
Publicado 2020
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25227“…Specific training alongside existing programs (HIV, malaria), early diagnosis of the disease, and the creation of patient advocacy groups should be implemented to improve SCD patient care.…”
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25228por Reinke, Sören, Thakur, Aneesh, Gartlan, Cillian, Bezbradica, Jelena S., Milicic, Anita“…However, there is an urgent need to improve immunogenicity of vaccines in order to protect mankind from life-threatening diseases such as AIDS, malaria or, most recently, COVID-19. Therefore, it is important to understand the cellular and molecular mechanisms of action of vaccine adjuvants, which generally trigger the innate immune system to enhance signal transition to adaptive immunity, resulting in pathogen-specific protection. …”
Publicado 2020
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25229por Zhang, Jianmei, Hunto, Stephanie Triseptya, Yang, Yoonyong, Lee, Jongsung, Cho, Jae Youl“…Tabebuia impetiginosa, a plant native to the Amazon rainforest and other parts of Latin America, is traditionally used for treating fever, malaria, bacterial and fungal infections, and skin diseases. …”
Publicado 2020
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25230por Chi, Jordi, Cova, Marta, de las Rivas, Matilde, Medina, Ana, Borges, Rafael Junqueira, Leivar, Pablo, Planas, Antoni, Usón, Isabel, Hurtado-Guerrero, Ramón, Izquierdo, Luis“…This work underscores the potential of apicomplexan GNA1 as a drug target against malaria.…”
Publicado 2020
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25231por Shah, Melisa M., Ndenga, Bryson A., Mutuku, Francis M., Vu, David M., Grossi-Soyster, Elysse N., Okuta, Victoria, Ronga, Charles O., Chebii, Philip K., Maina, Priscilla, Jembe, Zainab, Bosire, Carren M., Amugongo, Jael S., Sahoo, Malaya K., Huang, ChunHong, Weber, Jenna, Edgerton, Sean V., Hortion, Jimmy, Bennett, Shannon N., Pinsky, Benjamin A., LaBeaud, A. Desiree“…Of children with confirmed dengue viremia, 51.5% (150/291) had malaria parasitemia. All 4 dengue virus serotypes were detected, and phylogenetic analyses showed several viruses from novel lineages. …”
Publicado 2020
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25232“…Phylogenetic analysis has now shown that, besides the types IIA, IIB, IIC, and IID P-type ATPases, there exists a 5th subgroup of ATPases classified as ATP4-type ATPases, found in Plasmodium falciparum and Toxoplasma gondii. In malaria, for example, some drugs targeting PfATP4 destroy Na(+) homeostasis; these drugs, which include spiroindolones, are now in clinical trials. …”
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25233por Akorli, Esinam Abla, Ubiaru, Prince Chigozirim, Pradhan, Sabyasachi, Akorli, Jewelna, Ranford-Cartwright, Lisa“…These data support the use of bioproducts released by S. marcescens for malaria control based on transmission blocking in the vector.…”
Publicado 2022
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25234“…INTRODUCTION: Injuries remain a leading cause of death in many developing countries, accounting for more deaths than HIV, tuberculosis, and malaria combined. This study set out to determine the associated patient costs of reported injury cases at the Accident and Emergency Department of the Korle-Bu Teaching Hospital (KBTH) in Accra, Ghana. …”
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25235por Calçada, Carla, Silva, Miguel, Baptista, Vitória, Thathy, Vandana, Silva-Pedrosa, Rita, Granja, Diana, Ferreira, Pedro Eduardo, Gil, José Pedro, Fidock, David A., Veiga, Maria Isabel“…Artemisinin-based combination therapies (ACTs) have been vital in reducing malaria mortality rates since the 2000s. Their efficacy, however, is threatened by the emergence and spread of artemisinin resistance in Southeast Asia. …”
Publicado 2020
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25236por Matthews, Krista A., Senagbe, Kossi M., Nötzel, Christopher, Gonzales, Christopher A., Tong, Xinran, Rijo-Ferreira, Filipa, Bhanu, Natarajan V., Miguel-Blanco, Celia, Lafuente-Monasterio, Maria Jose, Garcia, Benjamin A., Kafsack, Björn F. C., Martinez, Elisabeth D.“…Our pharmacological studies of Jumonji activity in the malaria parasite provide evidence that inhibition of these enzymatic activities is detrimental to the parasite.…”
Publicado 2020
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25237por Bindschedler, Annina, Wacker, Rahel, Egli, Jessica, Eickel, Nina, Schmuckli‐Maurer, Jacqueline, Franke‐Fayard, Blandine M., Janse, Chris J., Heussler, Volker T.“…The protozoan parasite Plasmodium, causative agent of malaria, invades hepatocytes by invaginating the host cell plasma membrane and forming a parasitophorous vacuole membrane (PVM). …”
Publicado 2020
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25238por Sivakorn, Chaisith, Wilairatana, Polrat, Krudsood, Srivicha, Schultz, Marcus J., Techarang, Tachpon, Kheawsawaung, Khanittha, Dondorp, Arjen M.“…Impaired autonomic control of postural homeostasis resulting in orthostatic hypotension has been described in falciparum malaria. However, severe orthostatic intolerance in Plasmodium vivax has been rarely reported. …”
Publicado 2021
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25239por Visvikis-Siest, Sophie, Theodoridou, Danai, Kontoe, Maria-Spyridoula, Kumar, Satish, Marschler, Michael“…Starting from the treatment of malaria, as a first more personalized therapeutic approach, it highlights the need of new diagnostic tools and therapeutic regimens based on individuals' genetic background. …”
Publicado 2020
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25240por Moore, Adam J., Mangou, Khadidiatou, Diallo, Fatoumata, Sene, Seynabou D., Pouye, Mariama N., Sadio, Bacary D., Faye, Ousmane, Mbengue, Alassane, Bei, Amy K.“…This study demonstrates that PfRh5 remains highly conserved and functionally essential, even in a highly endemic setting, supporting continued development as a strain-transcendent malaria vaccine target.…”
Publicado 2021
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