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25361por Jimenez-Fernandez, Raquel, Rodriguez Vázquez, Rocío, Marín-Morales, Dolores, Herraiz-Soria, Elena, Losa-Iglesias, Marta Elena, Becerro-de-Bengoa-Vallejo, Ricardo, Corral-Liria, Inmaculada“…FTM offers a cure for malaria and treatments for reproductive health issues, bone fractures and cultural illnesses. …”
Publicado 2023
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25362por Liffner, Benjamin, Cepeda Diaz, Ana Karla, Blauwkamp, James, Anaguano, David, Frölich, Sonja, Muralidharan, Vasant, Wilson, Danny W., Dvorin, Jeffrey, Absalon, Sabrina“…Here, we apply U-ExM to the human malaria parasite Plasmodium falciparum during the asexual blood stage of its lifecycle to understand how this parasite is organized in three-dimensions. …”
Publicado 2023
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25363por Natasha, Jafar Ali, Yasmin, Abd Rahaman, Sharma, Reuben Sunil Kumar, Nur-Fazila, Saulol Hamid, Nur-Mahiza, Md Isa, Arshad, Siti Suri, Mohammed, Hussni Omar, Kumar, Kiven, Loong, Shih Keng, Ahmad Khusaini, Mohd Kharip Shah“…Being a tropical country with a conducive environment for mosquitoes, mosquito-borne illnesses such as dengue, chikungunya, lymphatic filariasis, malaria, and Japanese encephalitis are prevalent in Malaysia. …”
Publicado 2023
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25364“…This modification is generally catalyzed by three types of prenyl transferases, which include farnesyl transferase (FT), geranylgeranyl transferase (GGT-1) and Rab geranylgeranyl transferase (GGT-2). Studies in malaria parasites showed that these parasites contain prenylated proteins, which are proposed to play multiple functions in parasites. …”
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25365por Guo, Haohao, Wang, Ziyang, Ma, Runsheng, Chen, Xin, Li, Hongqiang, Tang, Yifeng, Du, Gongbo, Zhang, Yifei, Yin, Detao“…Other pyroptosis-inducing drugs, such as metformin, dihydroartemisinin, and famotidine, were used to control blood glucose, treat malaria, and regulate blood lipid levels and are effective tumor treatments. …”
Publicado 2023
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25366por Yasir, Muhammad, Park, Jinyoung, Han, Eun-Taek, Park, Won Sun, Han, Jin-Hee, Kwon, Yong-Soo, Lee, Hee-Jae, Chun, Wanjoo“…Plasmodium vivax (P. vivax) is one of the human’s most common malaria parasites. P. vivax is exceedingly difficult to control and eliminate due to the existence of extravascular reservoirs and recurring infections from latent liver stages. …”
Publicado 2023
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25367por Ferrando-Bernal, Manuel“…Several hypotheses have been suggested to explain the origin of the disease, such as an iron deficiency diet, low B12 intake, malaria caused by Plasmodium spp., low haemoglobin levels or low vitamin D levels. …”
Publicado 2023
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25368por Niederreiter, Marlene, Klein, Julia, Arndt, Kerstin, Werner, Jens, Mayer, Barbara“…The anti-malaria drug Artesunate (ART) shows strong anti-cancer effects in vitro; however, it shows only marginal treatment results in clinical cancer studies. …”
Publicado 2023
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25369por Wenz, Christoph, Simon, Caroline Sophie, Romão, Tatiany Patricia, Stürmer, Vanessa Saskia, Machado, Marta, Klages, Natacha, Klemmer, Anja, Voß, Yannik, Ganter, Markus, Brochet, Mathieu, Guizetti, Julien“…Malaria-causing parasites achieve rapid proliferation in human blood through multiple rounds of asynchronous nuclear division followed by daughter cell formation. …”
Publicado 2023
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25370“…Pyrethroid resistance in Aedes aegypti is widespread in southern Vietnam because the photostable 2nd generation pyrethroids have been used in large amounts over extensive areas for malaria and dengue vector control. In our previous report in 2009, F1534C, one of the point mutations in the voltage-sensitive sodium channel (VSSC) in Ae. aegypti, was widespread at high frequency in south and central area. …”
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25371“…These experimental conditions should mimic the transport of the drug inside malaria-infected erythrocytes through parasitophorous membranes. …”
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25372por Deni, Ioanna, Stokes, Barbara H., Ward, Kurt E., Fairhurst, Kate J., Pasaje, Charisse Flerida A., Yeo, Tomas, Akbar, Shirin, Park, Heekuk, Muir, Ryan, Bick, Daniella S., Zhan, Wenhu, Zhang, Hao, Liu, Yi Jing, Ng, Caroline L., Kirkman, Laura A., Almaliti, Jehad, Gould, Alexandra E., Duffey, Maëlle, O'Donoghue, Anthony J., Uhlemann, Anne-Catrin, Niles, Jacquin C., da Fonseca, Paula C.A., Gerwick, William H., Lin, Gang, Bogyo, Matthew, Fidock, David A.“…Dual targeting of P. falciparum proteasome subunits using covalent inhibitors provides a potential strategy for restoring artemisinin activity and combating the spread of drug-resistant malaria.…”
Publicado 2023
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25373“…In this review, the function and importance of lipid asymmetry in the interactions of intracellular protozoan parasites with the target and immune cells of the host are highlighted. The malaria parasite Plasmodium infects red blood cells and extensively refurbishes these terminally differentiated cells. …”
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25374por Shekhawat, Jayshree, Kumar, Deepak, Bhardwaj, Pankaj, Meena, Durga S., Garg, Mahendra Kumar“…Laboratory-confirmed Dengue, Malaria, and hepatitis were reported more in urban Jodhpur. …”
Publicado 2023
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25375por Kuehnel, Ronja Marie, Ganga, Emma, Balestra, Aurélia C., Suarez, Catherine, Wyss, Matthias, Klages, Natacha, Brusini, Lorenzo, Maco, Bohumil, Brancucci, Nicolas, Voss, Till S., Soldati, Dominique, Brochet, Mathieu“…Critical events in the life cycle of malaria-causing parasites depend on cyclic guanosine monophosphate homeostasis by guanylyl cyclases (GCs) and phosphodiesterases, including merozoite egress or invasion of erythrocytes and gametocyte activation. …”
Publicado 2023
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25376por Ahmed, Safaa, Pestana, Kareen, Ford, Anthony, Elfaki, Mohammed, Gamil, Eiman, Elamin, Arwa F., Hamad, Samuel Omer, Elfaki, Tarig Mohamed, Abukashawa, Sumaia Mohamed Ahmed, Lo, Eugenia, Abdel Hamid, Muzamil M.“…In this study, the prevalence and type of PvDBP duplications, and its relationship to demographic and clinical features were investigated. A total of 200 malaria-suspected blood samples were collected from health facilities in Khartoum, River Nile, and Al-Obied. …”
Publicado 2023
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25377por Mbye, Haddijatou, Bojang, Fatoumata, Jaiteh, Fatou Kene, Jawara, Aminata, Njie, Bekai, Correa, Simon, D'Alessandro, Umberto, Amambua-Ngwa, Alfred“…Therefore, the antimalarial activity of 125 compounds from the Medicine for Malaria Ventures (MMV) pathogen box was determined. …”
Publicado 2023
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25378por Salami, Raimat Korede, Valente de Almeida, Sara, Gheorghe, Adrian, Njenga, Sarah, Silva, Wnurinham, Hauck, Katharina“…The included studies estimate that substandard and falsified antimalarial medicines can account from 10% to ∼40% of total annual malaria costs, and SFMs affect rural and poor populations disproportionately. …”
Publicado 2023
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25379Chromatin structure can introduce systematic biases in genome-wide analyses of Plasmodium falciparum“…Background: The maintenance, regulation, and dynamics of heterochromatin in the human malaria parasite, Plasmodium falciparum, has drawn increasing attention due to its regulatory role in mutually exclusive virulence gene expression and the silencing of key developmental regulators. …”
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25380“…The results indicate changes in the choline/membrane components and other metabolites during the early stage of malaria. Conclusions: The paper reports the comprehensive characterization of the metabolome of mouse RBCs. …”
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