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25481por Holm, Inge, Lavazec, Catherine, Garnier, Thierry, Mitri, Christian, Riehle, Michelle M., Bischoff, Emmanuel, Brito-Fravallo, Emma, Takashima, Eizo, Thiery, Isabelle, Zettor, Agnes, Petres, Stephane, Bourgouin, Catherine, Vernick, Kenneth D., Eiglmeier, Karin“…Functional studies have demonstrated a role for the Anopheles gambiae APL1A gene in resistance against the human malaria parasite, Plasmodium falciparum. Here, we exhaustively characterize the structure of the APL1 locus and show that three structurally different APL1A alleles segregate in the Ngousso colony. …”
Publicado 2012
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25482“…The presence of different haplotypes in MSP-1 gene shows that several P. vivax strains exist in malaria endemic areas of Iran.…”
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25483“…BACKGROUND: Insecticides are an effective and practical tool for reducing malaria transmission but the development of resistance to the insecticides can potentially compromise controls efforts. …”
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25484por Malmberg, Maja, Ferreira, Pedro E., Tarning, Joel, Ursing, Johan, Ngasala, Billy, Björkman, Anders, Mårtensson, Andreas, Gil, José P.“…Multidrug-resistant Plasmodium falciparum is a major threat to global malaria control. Parasites develop resistance by gradually acquiring genetic polymorphisms that decrease drug susceptibility. …”
Publicado 2013
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25485“…A major bioactive marker of this genus is an alkaloid berberine, which is known for its activity against cholera, acute diarrhea, amoebiasis, and latent malaria and for the treatment of oriental sore caused by Leishmania tropica. …”
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25486“…METHODS: Key assay parameters for a range of commercially available luminogenic substrates are determined and compared to those measured using a Malaria Sybr Green I fluorescence assay. In addition, the short-term temporal effects of anti-malarial compounds are evaluated using both bioluminescent and fluorescent assay platforms. …”
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25487“…Plasmodium knowlesi, a zoonotic malarial parasite, has become a major cause of human malaria in Southeast Asia. Trypanosoma evansi and Trypanosoma lewisi, which normally infect horses and rodents respectively, have been reported to cause human trypanosomiasis in India. …”
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25488por Wierk, Jannika Katharina, Langbehn, Annette, Kamper, Maria, Richter, Stefanie, Burda, Paul-Christian, Heussler, Volker Theo, Deschermeier, Christina“…In the genomes of protozoan Plasmodium parasites, the causative agents of malaria, two genes encoding kinases with significant homology to other eukaryotic MAPKs have been identified (mapk1, mapk2). …”
Publicado 2013
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25489“…AIMS: The present study aimed to determine the allelic variants distribution of MSP1 and MSP2 and multiplicity of infection in P. falciparum field isolates from Kosti, central Sudan, an area characterized by seasonal malaria transmission. MATERIALS AND METHODS: Total 121 samples (N = 121) were collected during a cross-sectional survey between March and April 2003. …”
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25490por Moussiliou, Azizath, De Tove, Yolande Sissinto-Savi, Doritchamou, Justin, Luty, Adrian JF, Massougbodji, Achille, Alifrangis, Michael, Deloron, Philippe, Ndam, Nicaise Tuikue“…Association between the persistence of parasites and malaria consequences, were investigated. Recurrent parasites were genotyped to identify recrudescences from re-infections. …”
Publicado 2013
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25491“…In this study, we investigated retention and rearrangement of positionally overlapping genes between the mosquitoes Aedes aegypti (dengue virus vector) and Anopheles gambiae (malaria vector). The overlapping gene pairs of A. aegypti were further compared with orthologs of other selected insects to conduct several hypothesis driven investigations relating to the evolution and rearrangement of overlapping genes. …”
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25492por Currà, Chiara, Di Luca, Marco, Picci, Leonardo, de Sousa Silva Gomes dos Santos, Carina, Siden-Kiamos, Inga, Pace, Tomasino, Ponzi, Marta“…Our results suggest that ETRAMP members may be viewed as new potential candidates for malaria control.…”
Publicado 2013
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25493por Schuck, Desiree C, Ferreira, Sabrina B, Cruz, Laura N, da Rocha, David R, Moraes, Miriam S, Nakabashi, Myna, Rosenthal, Philip J, Ferreira, Vitor F, Garcia, Celia RS“…One member of this class, atovaquone, is combined with proguanil in Malarone®, an important drug for the treatment and prevention of malaria. METHODS: Anti-malarial activity was assessed in vitro for a series of 3-alkyl-2-hydroxy-1,4-naphthoquinones (N1-N5) evaluating the parasitaemia after 48 hours of incubation. …”
Publicado 2013
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25494“…All travellers were given the advice on how to dress, feed and protect against malaria.…”
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25495por Kalani, Komal, Agarwal, Jyoti, Alam, Sarfaraz, Khan, Feroz, Pal, Anirban, Srivastava, Santosh Kumar“…Malaria is one of the most prevailing fatal diseases causing between 1.2 and 2.7 million deaths all over the world each year. …”
Publicado 2013
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25496por Akinyi, Sheila, Hayden, Tonya, Gamboa, Dionicia, Torres, Katherine, Bendezu, Jorge, Abdallah, Joseph F., Griffing, Sean M., Quezada, Wilmer Marquiño, Arrospide, Nancy, De Oliveira, Alexandre Macedo, Lucas, Carmen, Magill, Alan J., Bacon, David J., Barnwell, John W., Udhayakumar, Venkatachalam“…The majority of malaria rapid diagnostic tests (RDTs) detect Plasmodium falciparum histidine-rich protein 2 (PfHRP2), encoded by the pfhrp2 gene. …”
Publicado 2013
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25497“…Results: During the study period, 90 (34.75%) presented with typical features of DF, 28 (31.11%) were dengue proven, seven (7.7%) proved to be of malaria in which malarial parasites were found positive in the peripheral blood, while the remaining 55 (61.11%) patients were dengue probable. …”
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25498por Ding, Dalian, Qi, Weidong, Yu, Dongzhen, Jiang, Haiyan, Han, Chul, Kim, Mi-Jung, Katsuno, Kana, Hsieh, Yun Hua, Miyakawa, Takuya, Salvi, Richard, Tanokura, Masaru, Someya, Shinichi“…BACKGROUND: Mefloquine is widely used for the treatment of malaria. However, this drug is known to induce neurological side effects including depression, anxiety, balance disorder, and sensorineural hearing loss. …”
Publicado 2013
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25499por Ryu, Ji Choul, Park, Sang Mi, Hwangbo, Min, Byun, Sung Hui, Ku, Sae Kwang, Kim, Young Woo, Kim, Sang Chan, Jee, Seon Young, Cho, Il Je“…Artemisia apiacea Hance is one of the most widely used herbs for the treatment of malaria, jaundice, and dyspeptic complaint in oriental medicine. …”
Publicado 2013
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25500Fosphenytoin for seizure prevention in childhood coma in Africa: A randomized clinical trial()()()()por Gwer, Samson A., Idro, Richard I., Fegan, Gregory, Chengo, Eddie M., Mpoya, Ayub, Kivaya, Esther, Crawley, Jane, Muchohi, Simon N., Kihara, Michael N., Ogutu, Bernhards R., Kirkham, Fenella J., Newton, Charles R.“…RESULTS: We recruited 173 children (median age, 2.6 [interquartile range, 1.7-3.7] years) into the study; 110 had cerebral malaria, 8 had bacterial meningitis, and 55 had encephalopathies of unknown etiology. …”
Publicado 2013
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