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  1. 25581
    “…We conducted a cluster randomized trial of the effects of the integrated community case management of childhood illness (iCCM) strategy on careseeking for and coverage of correct treatment of suspected pneumonia, diarrhea, and malaria, and mortality among children aged 2–59 months in 31 districts of the Oromia region of Ethiopia. …”
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    Effects of the integrated Community Case Management of Childhood Illness Strategy on Child Mortality in Ethiopia: A Cluster Randomized Trial
  2. 25582
    “…However, genome-wide studies involving Plasmodium falciparum, the causative agent of malaria, have been rather few, at lower resolution (mostly using ChIP-on-chip), and covering limited number of histone modifications. …”
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    Plasmodium falciparum epigenome: A distinct dynamic epigenetic regulation of gene expression
  3. 25583
    “…Plasmodium vivax is most wide spread and a neglected malaria parasite. There is a lack of information on parasite biology of this species. …”
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    Plasmodium vivax Tryptophan Rich Antigen PvTRAg36.6 Interacts with PvETRAMP and PvTRAg56.6 Interacts with PvMSP7 during Erythrocytic Stages of the Parasite
  4. 25584
    “…Etiologic diagnoses associated with AKI included sepsis, malaria, and ARDS. Mortality was 52.5%. APACHE II (OR 4.550; 95% CI 1.2–17.5, p = 0.028), mechanical ventilation (OR 13.063; 95% CI 2.3–72, p = 0.003), and need for vasopressors (OR 16.8; 95% CI 3.4–82.6, p = 0.001) had statistically significant association with mortality. …”
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    Clinical Characteristics and 30-Day Outcomes of Intermittent Hemodialysis for Acute Kidney Injury in an African Intensive Care Unit
  5. 25585
    “…Croton guatemalensis Lotsy (CGL), known as “copalchi” in Chiapas, Mexico, is used for the treatment of fever, abdominal pain and malaria and also as a remedy for chills and for treating rheumatism. …”
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    Antinociceptive effect of aqueous extracts from the bark of Croton guatemalensis Lotsy in mice
  6. 25586
    por Chinsembu, Kazhila C.
    Publicado 2016
    “…Faced with critical shortages of staff, long queues, and stigma at public health facilities in Livingstone, Zambia, persons who suffer from HIV/AIDS-related diseases use medicinal plants to manage skin infections, diarrhoea, sexually transmitted infections, tuberculosis, cough, malaria, and oral infections. In all, 94 medicinal plant species were used to manage HIV/AIDS-related diseases. …”
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    Ethnobotanical Study of Plants Used in the Management of HIV/AIDS-Related Diseases in Livingstone, Southern Province, Zambia
  7. 25587
    “…The adoption of Artemisinin based combination therapies (ACT) constitutes a basic strategy for malaria control in sub-Saharan Africa. Moreover, since cases of ACT resistance have been reported in South-East Asia, the need to understand P. falciparum resistance mechanism to ACT has become a global research goal. …”
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    Artesunate-Amodiaquine and Artemether-Lumefantrine Therapies and Selection of Pfcrt and Pfmdr1 Alleles in Nanoro, Burkina Faso
  8. 25588
    “…The ability to knockdown individual genes selectively via this reverse genetic technique has allowed many researchers to rapidly uncover the biological roles of numerous genes within many organisms, by evaluation of loss-of-function phenotypes. In the major human malaria vector Anopheles gambiae, the predominant method used to reduce the function of targeted genes involves injection of double-stranded (dsRNA) into the hemocoel of the adult mosquito. …”
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    RNAi Trigger Delivery into Anopheles gambiae Pupae
  9. 25589
    “…The retarded invasion mediated by sulfated polysaccharides, and the ensuing prolonged exposure of Plasmodium to the immune system, can be explored for the design of new therapeutic approaches against malaria where heparin-related polysaccharides of low anticoagulating activity could play a dual role as drugs and as potentiators of immune responses.…”
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    Marine organism sulfated polysaccharides exhibiting significant antimalarial activity and inhibition of red blood cell invasion by Plasmodium
  10. 25590
    “…RESULTS: 67% of the patients were male with a median age of the study group of 24 years (IQR 15–33); 48% of the patients had an infectious disease—predominantly malaria with P. vivax or tuberculosis. Patients also reported with diseases which are less common—e.g. leishmaniasis, or even conditions rarely diagnosed in Europe—e.g. louse borne relapsing fever. …”
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    High Prevalence of Infectious Diseases and Drug-Resistant Microorganisms in Asylum Seekers Admitted to Hospital; No Carbapenemase Producing Enterobacteriaceae until September 2015
  11. 25591
    “…This is problematic for malaria parasites, as their sensitivity to drugs varies substantially during their 48-h developmental cycle. …”
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    Incorporating Stage-Specific Drug Action into Pharmacological Modeling of Antimalarial Drug Treatment
  12. 25592
    por Shivalli, Siddharudha
    Publicado 2016
    “…Differentiating scrub typhus from other endemic diseases like malaria, leptospirosis, dengue fever, typhoid, etc. is difficult due to overlapping clinical features and a lower positivity for eschars in Asian populations. …”
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    Diagnostic evaluation of rapid tests for scrub typhus in the Indian population is needed
  13. 25593
    “…Clinicians most often doubted the quality of haematology (67%), followed by malaria (53%) and CD4 (22%) test results. A total of 151 (70%) clinicians reported using laboratory tests results in patient management. …”
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    Use of laboratory test results in patient management by clinicians in Malawi
  14. 25594
    “…Many vectors of malaria and other infections spend most of their adult life within human homes, the environment where they bloodfeed and rest, and where control has been most successful. …”
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    A novel video-tracking system to quantify the behaviour of nocturnal mosquitoes attacking human hosts in the field
  15. 25595
    “…OBJECTIVE: Vernonia amygdalina (V. amygdalina) leaf is locally employed in the Southern region of Nigeria in the treatment of malaria infection. This study evaluated the in vivo antiplasmodial, antioxidant and immunomodulatory effect of ethanol extract of V. amygdalina leaf. …”
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    Antiplasmodial, antioxidant and immunomodulatory activities of ethanol extract of Vernonia amygdalina del. Leaf in Swiss mice
  16. 25596
    “…Soluble and functional PfHsp70-3, acquired by co-expression with PfHep-1, will facilitate the biochemical characterisation of this particular Hsp70 protein and its evaluation as a drug target for the treatment of malaria.…”
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    Plasmodium falciparum Hep1 Is Required to Prevent the Self Aggregation of PfHsp70-3
  17. 25597
    por McMichael, Anthony J
    Publicado 2014
    “…Meanwhile, for many millions of children in poor countries who hear little news and live with day-to-day fatalism, climate change threatens the fundamentals of life—food sufficiency, safe drinking water and physical security—and heightens the risks of diarrhoeal disease, malaria and other climate-sensitive infections. Poor and disadvantaged populations, and especially their children, will bear the brunt of climate-related trauma, disease and premature death over the next few decades and, less directly, from social disruption, impoverishment and displacement. …”
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    Climate Change and Children: Health Risks of Abatement Inaction, Health Gains from Action
  18. 25598
    “…The widespread distribution and relapsing nature of Plasmodium vivax infection present major challenges for malaria elimination. To characterise the genetic diversity of this parasite within individual infections and across the population, we performed deep genome sequencing of >200 clinical samples collected across the Asia-Pacific region, and analysed data on >300,000 SNPs and 9 regions of the genome with large copy number variations. …”
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    Genomic analysis of local variation and recent evolution in Plasmodium vivax
  19. 25599
    “…We have shown previously that sex ratio distortion can be generated synthetically in the main human malaria vector Anopheles gambiae, by selectively destroying the X-chromosome during spermatogenesis, through the activity of a naturally-occurring endonuclease that targets a repetitive rDNA sequence highly-conserved in a wide range of organisms. …”
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    A CRISPR-Cas9 sex-ratio distortion system for genetic control
  20. 25600
    “…Till date, several miRNAs have been reported as a molecular biomarker in infectious diseases, such as miRNA-150 and miRNA-146b-5p in human immunodeficiency virus (HIV); miRNA-122, miRNA-21, and miRNA-34a in hepatitis; miRNA-361-5p and miRNA-29c in tuberculosis; miRNA-16 and miRNA-451 in malaria and miRNA-181 in Helicobacter pylori infection. …”
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    Circulating MicroRNAs: Potential and Emerging Biomarkers for Diagnosis of Human Infectious Diseases
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