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25841“…Top adaptive eQTL outliers include rs1043809, rs66899053, and rs2814778 (a SNP that is associated with malaria resistance). We found that effect sizes of eQTLs were negatively correlated with population branch statistics and that adaptive eQTLs affect two-thirds as many tissues as do non-adaptive eQTLs. …”
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25842por Ma, Zhaowu, Woon, Clariis Yi-Ning, Liu, Chen-Guang, Cheng, Jun-Ting, You, Mingliang, Sethi, Gautam, Wong, Andrea Li-Ann, Ho, Paul Chi-Lui, Zhang, Daping, Ong, Peishi, Wang, Lingzhi, Goh, Boon-Cher“…Despite its established profile in malaria treatment, pharmacokinetic properties, anticancer potency, and current formulations that hinder the clinical translation of artemisinin as an anticancer agent, have been discussed. …”
Publicado 2021
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25843“…The study found students' knowledge of the causes and symptoms of malaria, cholera, and Sexually Transmitted Infections (STIs) to be appreciably high as a result of readings from textbooks and health professionals. …”
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25844por Tempfer, Clemens“…If pregnant women or women attempting to become pregnant plan long-distance travel, immunization requirements should be discussed, especially if their travel destination is within an area endemic for diseases such as malaria, yellow fever, tuberculosis, hepatitis, human immunodeficiency virus-associated diseases, leishmaniosis, toxoplasmosis, and Japanese encephalitis. …”
Publicado 2022
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25845por Kucharska, Iga, Hossain, Lamia, Ivanochko, Danton, Yang, Qiren, Rubinstein, John L, Pomès, Régis, Julien, Jean-Philippe“…Malaria is a global health burden, with Plasmodium falciparum (Pf) and Plasmodium vivax (Pv) responsible for the majority of infections worldwide. …”
Publicado 2022
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25846por Schappo, Ana Paula, Bittencourt, Najara C, Bertolla, Leticia P, Forcellini, Sofia, da Silva, Ana Beatriz Iung Enembreck, dos Santos, Hellen Geremias, Gervásio, João Henrique, Lacerda, Marcus VG, Lopes, Stefanie CP, Costa, Fabio TM, Albrecht, Letusa“…BACKGROUND: Plasmodium vivax, the major cause of malaria in Latin America, has a large subtelomeric multigene family called vir. …”
Publicado 2022
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25847por Grundy, Brian, Panzner, Ursula, Liu, Jie, Jeon, Hyon Jin, Im, Justin, von Kalckreuth, Vera, Konings, Frank, Pak, Gi Deok, Cruz Espinoza, Ligia Maria, Bassiahi, Abdramane Soura, Gasmelseed, Nagla, Rakotozandrindrainy, Raphaël, Stroup, Suzanne, Houpt, Eric R., Marks, Florian“…A DBS qPCR Ct cutoff of 27 yielded 94.1% sensitivity and 95.1% specificity against the whole blood qPCR cutoff of 21 that has been previously suggested for malaria diagnosis. For other pathogens investigated, DBS testing yielded a sensitivity of only 8.5% but a specificity of 98.6% compared with whole blood qPCR. …”
Publicado 2022
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25848por Farmanpour-Kalalagh, Karim, Beyraghdar Kashkooli, Arman, Babaei, Alireza, Rezaei, Ali, van der Krol, Alexander R.“…It is derived from the herbal medicinal plant Artemisia annua and is best known for its use in treatment of malaria. However, recent studies also indicate the potential for artemisinin and related compounds, commonly referred to as artemisinins, in combating viral infections, inflammation and certain cancers. …”
Publicado 2022
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25849por Tungu, Patrick K., Waweru, John, Karthi, Sengodan, Wangai, James, Kweka, Eliningaya J.“…The success of long-lasting insecticidal nets (LLIN) as the primary method for preventing malaria is threatened by pyrethroid resistance in Anopheles vectors. …”
Publicado 2021
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25850“…Malaria is often most endemic in remote regions where diagnostic microscopy services are unavailable. …”
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25851“…However, since the 2000s, many African countries have benefited from massive investments to strengthen laboratory capacities through projects fighting priority diseases (HIV/AIDS, tuberculosis, malaria). This review examined the laboratory capacities of the Economic Community of Central African States (ECCAS). …”
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25852por Wani, Kaiser Iqbal, Zehra, Andleeb, Choudhary, Sadaf, Naeem, M., Khan, M. Masroor A., Khan, Riyazuddeen, Aftab, Tariq“…Artemisia annua is a medicinal plant particularly known for the production of a sesquiterpene lactone artemisinin; a specialty metabolite known for its efficacy in the treatment of malaria by killing different strains of Plasmodium falciparum due to radicals released upon the cleavage of its endoperoxide motif. …”
Publicado 2022
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25853por Sut, Stefania, Tahmasebi, Aminallah, Ferri, Nicola, Ferrarese, Irene, Rossi, Ilaria, Panighel, Giovanni, Lupo, Maria Giovanna, Maggi, Filippo, Karami, Akbar, Dall’Acqua, Stefano“…Scheen and V.A.Albert (Lamiaceae) is used in Iranian traditional medicine to treat malaria, diabetes, hyperlipidemia, rheumatism and cardiovascular diseases. …”
Publicado 2022
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25854“…In contrast to other Apicomplexa, including the malaria parasite Plasmodium, the entire Cryptosporidium life cycle unfolds in a single host in less than 3 days. …”
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25855por Huang, Mofei, Xiong, Donghai, Pan, Jing, Zhang, Qi, Wang, Yian, Myers, Charles R., Johnson, Bryon D., Hardy, Micael, Kalyanaraman, Balaraman, You, Ming“…Atovaquone, an FDA‐approved drug for malaria, is known to inhibit mitochondrial electron transport. …”
Publicado 2022
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25856“…The biological activities of marine alkaloids mainly manifest in the form of anti-tumor, anti-fungus, anti-viral, anti-malaria, and anti-osteoporosis properties. Many marine alkaloids have good medicinal prospects and can possibly be used as anti-tumor, anti-viral, and anti-fungal clinical drugs or as lead compounds. …”
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25857por CELLARIER, Dorian, PONS, Frédéric, REBARDY, Marion, PAEZ, Jessica, ROMMEL, Sarah, MOSCATO, Carmelo, GANTOIS, Natacha, LABOURDERE, Eléna, HOWE, Rhiannon, CELLARIER, Gilles“…METHOD: We realized a retrospective study, evaluating epidemiologic, clinical, biological and electrocardiographic data for patients treated for falciparum malaria, between August 31(st) and November 3(rd), 2017 in the Pôle de santé unique on the Camp Kosseï of N'Djamena. …”
Publicado 2021
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25858por Crabtree, Juliet N., Caffrey, Daniel R., de Souza Silva, Leandro, Kurt-Jones, Evelyn A., Dobbs, Katherine, Dent, Arlene, Fitzgerald, Katherine A., Golenbock, Douglas T.“…Assay for transposase-accessible chromatin with high-throughput sequencing (ATAC-Seq) on monocytes from patients with malaria showed persistently open chromatin at genes that appeared to be trained in vitro. …”
Publicado 2022
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25859por Abdulrahman, Mahmoud Dogara, Zakariya, Ali Muhammad, Hama, Harmand A., Hamad, Saber W., Al-Rawi, Sawsan S., Bradosty, Sarwan W., Ibrahim, Ahmad H.“…Biological reports and traditional applications including management of diabetes and treatment of malaria, digestive issues, typhoid, liver complaints, weakness, skin infections, urinary disorders, obesity, diarrhoea, and sleeplessness have all been treated with different parts of Z. spina all over the globe. …”
Publicado 2022
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25860por Soriano, Vicente, Alvarez, Carmen, Edagwa, Benson, de Mendoza, Carmen, Montoya, Noemí, Treviño, Ana, Gendelman, Howard“…Viral hepatitis is among the top four causes of mortality globally, causing 1.4 million deaths each year, exceeding tuberculosis, malaria and human immunodeficiency virus. Hepatitis B and C are responsible for 90% of hepatitis deaths, and the remaining 10% are caused by other hepatitis viruses. …”
Publicado 2022
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