“…BACKGROUND: To manage the kdr pyrethroid-resistance in Anopheline malaria vectors, new compounds or new strategies are urgently needed. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Further studies on comparison of isotopic and non-isotopic assays are needed to establish a standardized in vitro assay protocol to survey malaria drug resistance.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: For Anopheline mosquitoes, the vectors of human malaria, genetic variation in male reproductive success can have important consequences for any control strategy based on the release of transgenic or sterile males. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHOD: Parasite infections obtained from 153 Sudanese patients with uncomplicated falciparum malaria treated with SP or SP + chloroquine, were successfully genotyped at nine codons in the dhfr/dhps genes by PCR-ELISA. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This will guide not only appropriate interventions to deal with established multidrug resistant strains of malaria, but also facilitate prompt action when new strains of drug resistant plasmodia first emerge. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…While climate-based EWS have been developed for malaria, no standard protocol to evaluate and compare EWS has been proposed. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Re-treatment with unsupervised quinine ± doxycycline resulted in further recurrence of malaria in 48% (95% CI 31–65) of P. falciparum infections and 70% (95% CI 37–100) of P. vivax infections. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Patterns of genetic structure among mosquito vector populations in islands have received particular attention as these are considered potentially suitable sites for experimental trials on transgenic-based malaria control strategies. In this study, levels of genetic differentiation have been estimated between populations of Anopheles gambiae s.s. from the islands of Bioko and Annobón, and from continental Equatorial Guinea (EG) and Gabon. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The small size of the rosettes formed when P. falciparum was grown in blood group O RBC may be the in vitro correlate of the relative protection against cerebral malaria afforded by belonging to blood group O rather than to blood group A or B. …”
Enlace del recurso
Enlace del recurso

“…We also show that when fused to the COOH terminus of hGH, the putative GPI signal from the malaria circumsporozoite (CS) protein produces low levels of GPI- anchored hGH, suggesting that the CS protein is indeed GPI linked, but that the CS protein GPI signal, like the VSG-signal, functions poorly in COS cells. …”
Enlace del recurso
Enlace del recurso

“…In both cases, the injections produced clinical malaria and in one, an abnormally severe course was observed. 3. …”
Enlace del recurso
Enlace del recurso

“…This constitutes the first example of a sequential expression of antigens in a malaria parasite; it indicates that, in P. fragile, antigenic variation is not the result of random mutations selected by antibody. …”
Enlace del recurso
Enlace del recurso

“…The surfaces of the infected erythrocyte (IE) and the merozoite, two developmental stages of malaria parasites, expose antigenic determinants to the host immune system. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSION: Finding the fixed level of CQ resistance polymorphisms (pfcrt 76T) suggests that CQ must be withdrawn from the current treatment strategy in Iran, while SP may remain the treatment of choice for uncomplicated malaria.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…During the asexual stage of malaria infection, the intracellular parasite exports membranes into the erythrocyte cytoplasm and lipids and proteins to the host cell membrane, essentially "transforming" the erythrocyte. …”
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: These results highlight the need for more research to understand the forces driving the evolution of insecticide resistance in malaria vectors and to regularly monitor resistance in mosquito populations of Africa.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…An unaddressed threat is whether Barred Owls could be a source of novel strains of disease such as avian malaria (Plasmodium spp.) or other blood parasites potentially harmful for Spotted Owls. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSION: A sensitive method for labelling surface and internal PfEMP1 with up to three different fluorochromes has been developed for laser scanning confocal optical microscopy and the analysis of the developmental expression of malaria adhesion antigens.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: In these remote communities, the heavy use of chloroquine to treat malaria likely selected for ciprofloxacin resistance in E. coli. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Antibodies are the main effectors against malaria blood-stage parasites. Evaluation of functional activities in immune sera from Phase 2a/b vaccine trials may provide invaluable information in the search for immune correlates of protection. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso