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  1. 26081
    “…We found that the rodent malaria parasite orthologue, P. berghei hexose transporter (PbHT) gene, was similarly refractory to knockout attempts. …”
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    Life cycle studies of the hexose transporter of Plasmodium species and genetic validation of their essentiality
  2. 26082
    “…BACKGROUND: Malaria kills. A single rectal dose of artesunate before referral can reduce mortality and prevent permanent disability. …”
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    Understanding caretakers' dilemma in deciding whether or not to adhere with referral advice after pre-referral treatment with rectal artesunate
  3. 26083
    “…Unusually for a eukaryote, the malaria parasite Plasmodium falciparum expresses dihydrofolate synthase (DHFS) and folylpolyglutamate synthase (FPGS) as a single bifunctional protein. …”
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    Characterisation of the bifunctional dihydrofolate synthase–folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition
  4. 26084
    “…BACKGROUND: Although Anopheles funestus is difficult to rear, it is crucial to analyse field populations of this malaria vector in order to successfully characterise mechanisms of insecticide resistance observed in this species in Africa. …”
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    High Level of Pyrethroid Resistance in an Anopheles funestus Population of the Chokwe District in Mozambique
  5. 26085
    por Moore, E M, Lockwood, D N
    Publicado 2010
    “…Lessons can be learnt from the management of diseases such as tuberculosis and malaria in terms of planning the switch to combination treatment. …”
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    Treatment of Visceral Leishmaniasis
  6. 26086
    “…Developing countries, where malaria is one of the most prevalent diseases, still rely on traditional medicine as a source for the treatment of this disease. …”
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    In Vitro Anti-plasmodial activity of Trigonella foenum–graecum L.
  7. 26087
    “…BACKGROUND: Invasion of the mosquito salivary glands by Plasmodium is a critical step for malaria transmission. From a SAGE analysis, we previously identified several genes whose expression in salivary glands was regulated coincident with sporozoite invasion of salivary glands. …”
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    Anopheles Gambiae PRS1 Modulates Plasmodium Development at Both Midgut and Salivary Gland Steps
  8. 26088
    “…BACKGROUND: Multi-drug resistant Plasmodium falciparum is a major obstacle to malaria control and is emerging as a complex phenomenon. …”
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    Antimalarial Exposure Delays Plasmodium falciparum Intra-Erythrocytic Cycle and Drives Drug Transporter Genes Expression
  9. 26089
    “…In the final model, nutritional and infectious factors, including malaria, were directly or indirectly associated with RCPF, but not with haemolysis. …”
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    Pathophysiological Mechanisms of Severe Anaemia in Malawian Children
  10. 26090
    “…These were followed by cerebral malaria, leptospirosis, and brain abscess as the cause of febrile encephalopathy in adults. …”
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    Acute febrile encephalopathy in adults from Northwest India
  11. 26091
    “…BACKGROUND: Entomopathogenic fungi, Metarhizium anisopliae and Beauveria bassiana, are promising bio-pesticides for application against adult malaria mosquito vectors. An understanding of the behavioural responses of mosquitoes towards these fungi is necessary to guide development of fungi beyond the 'proof of concept' stage and to design suitable intervention tools. …”
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    Anopheline and culicine mosquitoes are not repelled by surfaces treated with the entomopathogenic fungi Metarhizium anisopliae and Beauveria bassiana
  12. 26092
    “…Comparison tests between the new dataset and existing population datasets revealed important differences in population size distributions, and in population at risk of malaria estimates. These differences are particularly important in more densely populated areas and strongly depend on the settlement data used in the modelling approach. …”
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    A high resolution spatial population database of Somalia for disease risk mapping
  13. 26093
    “…We quantified and investigated the impacts of these key variables in a large-scale association study of a strongly selected trait of medical importance: pyrethroid resistance in the African malaria vector Anopheles gambiae. METHODOLOGY/PRINCIPAL FINDINGS: We genotyped ≈1500 resistance-phenotyped wild mosquitoes from Ghana and Cameroon using a 1536-SNP array enriched for candidate insecticide resistance gene SNPs. …”
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    Association Mapping of Insecticide Resistance in Wild Anopheles gambiae Populations: Major Variants Identified in a Low-Linkage Disequilbrium Genome
  14. 26094
    “…BACKGROUND: Artemether-lumefantrine is one of the most widely used anti-malarial drug combinations in the world with excellent tolerability and cure rates in adult and paediatric patients with uncomplicated falciparum malaria. The aim of this study was to evaluate the pharmacokinetics of artemether and its active metabolite, dihydroartemisinin, in healthy Pakistani volunteers. …”
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    Pharmacokinetics of artemether and dihydroartemisinin in healthy Pakistani male volunteers treated with artemether-lumefantrine
  15. 26095
    por Ndjinga, Julie K, Minakawa, Noboru
    Publicado 2010
    “…BACKGROUND: Malaria is the most prominent disease in the Democratic Republic of the Congo (DRC), and long-lasting insecticide-treated nets (LLINs) have been distributed free of charge since 2006 to combat the disease. …”
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    The importance of education to increase the use of bed nets in villages outside of Kinshasa, Democratic Republic of the Congo
  16. 26096
    “…Gullain Barre syndrome, Parkinson’s disease, and cerebral malaria were relatively rare causes of neurologic admissions in this study. …”
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    Pattern of neurological admissions in the tropics: Experience at Kano, Northwestern Nigeria
  17. 26097
    “…The case studies concern West Nile virus transmission in Senegal, tick-borne encephalitis incidence in Latvia, sandfly abundance in the French Pyrenees, Rift Valley Fever in the Ferlo (Senegal), West Nile Fever and the risk of malaria re-emergence in the Camargue, and rodent-borne Puumala hantavirus and Lyme borreliosis in Belgium. …”
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    Pathogenic landscapes: Interactions between land, people, disease vectors, and their animal hosts
  18. 26098
    “…Here the potential of this plant is explored for rapid production of precursors of artemisinin, a sesquiterpenoid compound that is used for malaria treatment. METHODOLOGY/PRINCIPAL FINDINGS: Biosynthetic genes leading to artemisinic acid, a precursor of artemisinin, were combined and expressed in N. benthamiana by agro-infiltration. …”
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    Nicotiana benthamiana as a Production Platform for Artemisinin Precursors
  19. 26099
    “…BACKGROUND: Insecticide-treated nets (ITNs) have been confirmed to be a very effective tool in malaria control. Two different delivery strategies for roll-out of ITN programmes have been the focus of debate in the last years: free distribution and distribution through commercial marketing systems. …”
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    Different delivery mechanisms for insecticide-treated nets in rural Burkina Faso: a provider's perspective
  20. 26100
    “…An understanding of host–pathogen interaction with respect to these physiological characteristics of the host is essential if we are to develop fungal formulations capable of reducing malaria transmission under field conditions. Here, two independent bioassays were conducted to study the effect of age and blood-feeding status on fungal infection and survival of Anopheles gambiae s.s. …”
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    Infection of Anopheles gambiae mosquitoes with entomopathogenic fungi: effect of host age and blood-feeding status
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