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26681“…The malaria development in the mosquito midgut is a complex process that results in considerable parasite losses. …”
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26682por Wichers, J. Stephan, Scholz, Judith A. M., Strauss, Jan, Witt, Susanne, Lill, Andrés, Ehnold, Laura-Isabell, Neupert, Niklas, Liffner, Benjamin, Lühken, Renke, Petter, Michaela, Lorenzen, Stephan, Wilson, Danny W., Löw, Christian, Lavazec, Catherine, Bruchhaus, Iris, Tannich, Egbert, Gilberger, Tim W., Bachmann, Anna“…During its intraerythrocytic development, the malaria parasite Plasmodium falciparum exposes variant surface antigens (VSAs) on infected erythrocytes to establish and maintain an infection. …”
Publicado 2019
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26683por Czechowski, Tomasz, Rinaldi, Mauro A., Famodimu, Mufuliat Toyin, Van Veelen, Maria, Larson, Tony R., Winzer, Thilo, Rathbone, Deborah A., Harvey, David, Horrocks, Paul, Graham, Ian A.“…Artemisinin, a sesquiterpene lactone produced by Artemisia annua glandular secretory trichomes, is the active ingredient in the most effective treatment for uncomplicated malaria caused by Plasmodium falciparum parasites. …”
Publicado 2019
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26684por Pratt-Riccio, Lilian Rose, Baptista, Bárbara de Oliveira, Torres, Vanessa Rodrigues, Bianco-Junior, Cesare, Perce-Da-Silva, Daiana de Souza, Riccio, Evelyn Kety Pratt, Lima-Junior, Josué da Costa, Totino, Paulo Renato Rivas, Cassiano, Gustavo Capatti, Storti-Melo, Luciane Moreno, Machado, Ricardo Luiz Dantas, de Oliveira-Ferreira, Joseli, Banic, Dalma Maria, Carvalho, Leonardo José de Moura, Daniel-Ribeiro, Cláudio Tadeu“…OBJECTIVES: To characterise the CSP variants in P. vivax isolates from individuals residing in a malaria-endemic region in Brazil and to profile these variants based on sensitivity to chloroquine and mefloquine. …”
Publicado 2019
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26685por Semenov, Alexey N., Shirshin, Evgeny A., Muravyov, Alexei V., Priezzhev, Alexander V.“…Selective control over these processes may serve as an indispensable tool for correction of hemorheological disorders, which accompany a number of systemic diseases (diabetes mellitus I&II, arterial hypertension, malaria, etc.). Activation of certain pathways involving adenylyl cyclase may provide fast adaptive regulation of RBC deformability (RBC-D). …”
Publicado 2019
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26686por Singh, Jagbir, Vijay, Sonam, Mansuri, Rani, Rawal, Ritu, Kadian, Kavita, Sahoo, Ganesh Chandra, Kumar, Mahesh, Sharma, Arun“…The inhibition of PfPMT may kill malaria parasite and hence is being considered as potential target for rational antimalarial drug designing. …”
Publicado 2019
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26687por Martinez-Villegas, Luis, Assis-Geraldo, Juliana, Koerich, Leonardo B., Collier, Travis C., Lee, Yoosook, Main, Bradley J., Rodrigues, Nilton B., Orfano, Alessandra S., Pires, Ana C. A. M., Campolina, Thais B., Nacif-Pimenta, Rafael, Baia-da-Silva, Djane C., Duarte, Ana P. M., Bahia, Ana C., Rios-Velásquez, Claudia M., Lacerda, Marcus V. G., Monteiro, Wuelton M., Lanzaro, Gregory C., Secundino, Nagila F. C., Pimenta, Paulo F. P.“…Here we report the complete 15,393 bp mtDNA sequences of Anopheles aquasalis, a Neotropical human malaria vector. When comparing its structure and base composition with other relevant and available anopheline mitogenomes, high similarity and conserved genomic features were observed. …”
Publicado 2019
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26688“…OBJECTIVE: One of the biggest health problems in the world, which occurs in more than 90 countries, is the spread of malaria. Cep-cepan leaves (Castanopsis costata), was empirically used as an antimalarial herb in North Sumatra. …”
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26689por Charani, Esmita, Cunnington, Aubrey J, Yousif, AlaEldin H A, Seed Ahmed, Mohammed, Ahmed, Ammar E M, Babiker, Souad, Badri, Shahinaz, Buytaert, Wouter, Crawford, Michael A, Elbashir, Mustafa I, Elhag, Kamal, Elsiddig, Kamal E, Hakim, Nadey, Johnson, Mark R, Miras, Alexander D, Swar, Mohamed O, Templeton, Michael R, Taylor-Robinson, Simon David“…At the same time, progress against communicable diseases has been slow, and the burden of chronic and endemic infections remains considerable, with parasitic diseases (such as malaria, leishmaniasis and schistosomiasis) causing substantial morbidity and mortality. …”
Publicado 2019
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26690por Ribeiro, Rosângela de Albuquerque, Galiza Neto, Gentil Claudino de, Furtado, Amanda da Silva, Ribeiro, Lucas Loiola Ponte Albuquerque, Kubrusly, Marcela Sobreira, Kubrusly, Elsie Sobreira“…Group B: failure of splenectomy (refractory) or no splenectomy indication or history of exposure to malaria or babesiosis and no response to corticoids or corticoid dependence: choose thrombopoietin receptor agonists: eltrombopag or romiplostim. …”
Publicado 2019
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26691por Clark, Sarah E., Burrack, Kristina S., Jameson, Stephen C., Hamilton, Sara E., Lenz, Laurel L.“…Here, we identified NK cell-intrinsic STAT3 activation as vital for IL-10 production during both systemic Listeria monocytogenes (Lm) infection and following IL-15 cytokine/receptor complex (IL15C) treatment for experimental cerebral malaria (ECM). In both contexts, conditional Stat3 deficiency in NK cells abrogated production of IL-10. …”
Publicado 2019
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26692por Kandasami, Stephanie, Shobiye, Hezekiah, Fakoya, Ade, Asiimwe, Sarah, Inimah, Maureen, Etukoit, Michael, Morrison, Linden, Johnson, Michael, Dybul, Mark“…SETTING: A study was conducted on selected facilities in districts of country programs supported by The Global Fund to Fight AIDS, Tuberculosis, and Malaria. The aims of the study were to understand how facilities seek to improve the delivery and uptake of HIV services and to examine what innovative practices might be contributing to their success. …”
Publicado 2019
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26693por Tetteh-Quarcoo, Patience B., Akuetteh, Benjamin K., Owusu, Irene A., Quayson, Solomon E., Attah, Simon K., Armah, Robert, Afutu, Emmanuel, Afrah, Ama, Addo-Osafo, Kantanka, Smith, Cecilia, Gyasi, Richard K., Ayeh-Kumi, Patrick F.“…BACKGROUND: Schistosomiasis is the second major human parasitic disease next to malaria, in terms of socioeconomic and public health consequences, especially in sub-Saharan Africa. …”
Publicado 2019
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26694por Bowser, Diana M., Shepard, Donald S., Nandakumar, Allyala, Okunogbe, Adeyemi, Morrill, Tyler, Halasa-Rappel, Yara, Jordan, Monica, Mushi, Farida, Boyce, Carolyn, Oluwayemisi, Erhunmwunse“…FINDINGS: The results show that the provision of tetanus toxoid vaccination and malaria prophylaxis during pregnancy and improved labor and delivery during facility delivery contributed the most to mortality reductions for women, neonates and stillbirths in mHealth facilities versus non-mHealth facilities. …”
Publicado 2018
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26695por Brandstaedter, Christina, Delahunty, Claire, Schipper, Susanne, Rahlfs, Stefan, Yates, John R., Becker, Katja“…Using a pull-down assay based on mixed disulfide fishing, we characterized the thiol-dependent interactome of cytosolic Prx1a and mitochondrial Prx1m from the apicomplexan malaria parasite Plasmodium falciparum (Pf). Here, 127 cytosolic and 20 mitochondrial proteins that are components of essential cellular processes were found to interact with PfPrx1a and PfPrx1m, respectively. …”
Publicado 2019
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26696por Ravenhill, Benjamin J., Kanjee, Usheer, Ahouidi, Ambroise, Nobre, Luis, Williamson, James, Goldberg, Jonathan M., Antrobus, Robin, Dieye, Tandakha, Duraisingh, Manoj T., Weekes, Michael P.“…Red blood cells (RBCs) play a critical role in oxygen transport, and are the focus of important diseases including malaria and the haemoglobinopathies. Proteins at the RBC surface can determine susceptibility to disease, however previous studies classifying the RBC proteome have not used specific strategies directed at enriching cell surface proteins. …”
Publicado 2019
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26697“…Effect sizes are greatest for exposure to oil palm, rubber, and non-poultry based livestock farming and for hookworm (OR 2.42, CI 1.56–3.75), malaria (OR 2.00, CI 1.46–2.73), scrub typhus (OR 2.37, CI 1.41–3.96) and spotted fever group diseases (OR 3.91, CI 2.61–5.85). …”
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26698Effect of LongRange™ eprinomectin on Anopheles arabiensis by feeding on calves treated with the drug“…BACKGROUND: Misuse of long-lasting insecticidal nets together with resistance of vectors to most of the insecticides for indoor residual spraying and impregnated nets threaten malaria vector control interventions, requiring search for alternative control methods. …”
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26699Pyrethroid exposure alters internal and cuticle surface bacterial communities in Anopheles albimanuspor Dada, Nsa, Lol, Juan C., Benedict, Ana Cristina, López, Francisco, Sheth, Mili, Dzuris, Nicole, Padilla, Norma, Lenhart, Audrey“…A deeper understanding of the mechanisms underlying insecticide resistance is needed to mitigate its threat to malaria vector control. Following previously identified associations between mosquito microbiota and insecticide resistance, we demonstrate for the first time, the effects of pyrethroid exposure on the microbiota of F(1) progeny of field-collected Anopheles albimanus. …”
Publicado 2019
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26700“…A major determinant of pathogenicity in malaria caused by Plasmodium falciparum is the adhesion of parasite-infected erythrocytes to the vasculature or tissues of infected individuals. …”
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