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26701por Dusfour, Isabelle, Vontas, John, David, Jean-Philippe, Weetman, David, Fonseca, Dina M., Corbel, Vincent, Raghavendra, Kamaraju, Coulibaly, Mamadou B., Martins, Ademir J., Kasai, Shinji, Chandre, Fabrice“…Based on a plan developed for malaria vectors, here we propose some key activities to establish a global plan for IRM in Aedes spp.…”
Publicado 2019
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26702por Wilde, Mary-Louise, Triglia, Tony, Marapana, Danushka, Thompson, Jennifer K., Kouzmitchev, Alexei A., Bullen, Hayley E., Gilson, Paul R., Cowman, Alan F., Tonkin, Christopher J.“…Understanding the mechanisms behind host cell invasion by Plasmodium falciparum remains a major hurdle to developing antimalarial therapeutics that target the asexual cycle and the symptomatic stage of malaria. Host cell entry is enabled by a multitude of precisely timed and tightly regulated receptor-ligand interactions. …”
Publicado 2019
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26703por Malarski, Maya, Hasso-Agopsowicz, Mateusz, Soble, Adam, Mok, Wilson, Mathewson, Sophie, Vekemans, Johan“…Pneumococcal, typhoid and malaria vaccines were assigned highest value relative to antimicrobial resistance. …”
Publicado 2019
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26704por FITRI, Loeki Enggar, ALKARIMAH, Annisa, CAHYONO, Alfian Wika, LADY, Wahyudha Ngatiril, ENDHARTI, Agustina Tri, NUGRAHA, Rivo Yudhinata Brian“…BACKGROUND: Malaria eradication has been complicated by the repeated emergence of antimalarial drug resistances. …”
Publicado 2019
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26705por Faustino, Vera, Rodrigues, Raquel O., Pinho, Diana, Costa, Elísio, Santos-Silva, Alice, Miranda, Vasco, Amaral, Joana S., Lima, Rui“…The loss of the red blood cells (RBCs) deformability is related with many human diseases, such as malaria, hereditary spherocytosis, sickle cell disease, or renal diseases. …”
Publicado 2019
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26706por Thanapongpichat, Supinya, Khammanee, Thunchanok, Sawangjaroen, Nongyao, Buncherd, Hansuk, Tun, Aung Win“…In Thailand, previous studies indicated the genetic diversity of P. vivax in malaria-endemic regions such as the western part of Thailand bordering with Myanmar. …”
Publicado 2019
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26707por Oloume, Martine E., Mouliom, Abas, Melingui, Bernard F., Belinga, Suzanne, Nana, Julie S., Tejiokem, Mathurin, Sack, Francoise N., Manga, Jeanne, Epote, Annie R.“…Tests were performed for (1) HIV, (2) complete blood cell count, (3) hepatitis B virus, (4) malaria, (5) syphilis, (6) C-reactive protein and (7) hepatitis C virus. …”
Publicado 2019
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26708por Jerome, Hanna, Taylor, Callum, Sreenu, Vattipally B., Klymenko, Tanya, Filipe, Ana Da Silva, Jackson, Celia, Davis, Chris, Ashraf, Shirin, Wilson-Davies, Eleri, Jesudason, Natasha, Devine, Karen, Harder, Lisbeth, Aitken, Celia, Gunson, Rory, Thomson, Emma C.“…One patient had infection with malaria and mumps virus during the same admission. …”
Publicado 2019
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26709por Dowden, Justine, Mushamiri, Ivy, McFeely, Eric, Apat, Donald, Sacks, Jilian, Ben Amor, Yanis“…The most common diagnoses overall were upper respiratory tract infections, malaria and injury. A major limitation of this study is the non-comparability in information captured using the Male Clinic registers compared to control registers. …”
Publicado 2019
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26710por Angrisano, Fiona, Sala, Katarzyna A., Tapanelli, Sofia, Christophides, George K., Blagborough, Andrew M.“…Inhibiting transmission of Plasmodium is an essential strategy in malaria eradication, and the biological process of gamete fusion during fertilization is a proven target for this approach. …”
Publicado 2019
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26711“…Here, we report the unexpected finding that integration of the glms ribozyme sequence in the 3′ untranslated region of a gene encoding a HECT E3 ubiquitin ligase, termed Plasmodium falciparum ubiquitin transferase (PfUT), increased steady state RNA and protein levels 2.5-fold in the human malaria parasite P. falciparum. Overexpression of pfut resulted in an S/M phase-associated lengthening of the parasite’s intraerythrocytic developmental cycle and a reduced merozoite invasion efficiency. …”
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26712“…Twenty nine health conditions were treated out of which digestive disorders, malaria and respiratory tract infections were predominant. …”
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26713por Walz, Annabelle, Leroy, Didier, Andenmatten, Nicole, Mäser, Pascal, Wittlin, Sergio“…BACKGROUND: Drug efficacy against kelch 13 mutant malaria parasites can be determined in vitro with the ring-stage survival assay (RSA). …”
Publicado 2019
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26714por Tajik, Sahar, Sadeghi, Sedigheh, Iravani, Ayda, Khalili, Mitra, Arjmand, Mohammad, Din, Nassir-Ud, Vahabi, Farideh, Feiz-Haddad, Hossein, Lame-Rad, Behzad, Naddaf, Saied Reza, Zamani, Zahra“…BACKGROUND: Plasmodium falciparum is the protozoan parasite which causes malignant malaria of medical concern. Prime candidates for recombinant vaccine development are asexual stage antigens of P. falciparum, for example, merozoite surface proteins (MSP1 and MSP2) not given satisfactory results to date. …”
Publicado 2019
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26715“…Host seeking in the yellow fever mosquito, Aedes aegypti, and the African malaria mosquito, Anopheles coluzzii, relies on specific and generic host-derived odorants. …”
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26716“…Among the documented infectious diseases, the most frequently encountered was pneumonia, followed by malaria. There was no drug and therapeutic committee, hospital formulary or essential medicines list, and standard treatment guidelines for infectious diseases in the hospital. …”
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26717por Peng, Yu-chih, Qi, Yanwei, Zhang, Cui, Yao, Xiangyu, Wu, Jian, Pattaradilokrat, Sittiporn, Xia, Lu, Tumas, Keyla C., He, Xiao, Ishizaki, Takahiro, Qi, Chen-Feng, Holder, Anthony A., Myers, Timothy G., Long, Carole A., Kaneko, Osamu, Li, Jian, Su, Xin-zhuan“…Erythrocyte-binding-like (EBL) proteins are known to play an important role in malaria parasite invasion of red blood cells (RBCs); however, any roles of EBL proteins in regulating host immune responses remain unknown. …”
Publicado 2020
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26718por Tan, Michele S. Y., Davison, Dara, Sanchez, Mateo I., Anderson, Bethany M., Howell, Stephen, Snijders, Ambrosius, Edgington-Mitchell, Laura E., Deu, Edgar“…Clan CA cysteine proteases, also known as papain-like proteases, play important roles throughout the malaria parasite life cycle and are therefore potential drug targets to treat this disease and prevent its transmission. …”
Publicado 2020
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26719“…Although artesunate (ART) is generally accepted as a safe and well-tolerated first-line treatment of severe malaria, cases of severe side effects and toxicity of this compound are also documented. …”
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26720“…The most commonly investigated diseases were malaria and dengue fever. Around 12% of the publications did not report all the parameters used in their model. …”
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