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26721por Claudio-Piedras, Fabiola, Recio-Tótoro, Benito, Condé, Renaud, Hernández-Tablas, Juan M., Hurtado-Sil, Gerardo, Lanz-Mendoza, Humberto“…Our findings suggest that DNA methylation may constitute a key factor in vector competence, and a promising target for preventing malaria transmission.…”
Publicado 2020
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26722por Molina-Franky, Jessica, Cuy-Chaparro, Laura, Camargo, Anny, Reyes, César, Gómez, Marcela, Salamanca, David Ricardo, Patarroyo, Manuel Alfonso, Patarroyo, Manuel Elkin“…This review provides an overview of the current state and the main results of clinical trials for sporozoite-targeting vaccines (i.e. the parasite stage infecting the liver) carried out by research groups in areas having variable malaria transmission rates. However, none has led to promising results regarding the effective control of the disease, thereby making it necessary to complement such efforts at finding/introducing new vaccine candidates by adopting a multi-epitope, multi-stage approach, based on minimal subunits of the main sporozoite proteins involved in the invasion of the liver.…”
Publicado 2020
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26723“…BACKGROUND: Malaria is a global health problem that requires urgent need for new drugs. …”
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26724“…TRPM7 plays a key role in a variety of diseases, including neuronal death in ischemia, cancer, cardiac atrial fibrillation, malaria invasion. TRPM7 is aberrantly over-expressed in lung, liver and heart fibrosis. …”
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26725por Srinivas, Megan L., Yang, Eileen J., Shrestha, Priyanka, Wu, Dan, Peeling, Rosanna W., Tucker, Joseph D.“…The cases chosen for inclusion here demonstrate the importance of social innovation in diagnostics across different geographic, cultural, and health system contexts. They include malaria testing via schools in Malawi, cervical human papillomavirus (HPV) sample self-collection in Peru, and crowdsourcing human immunodeficiency virus (HIV) testing in China. …”
Publicado 2020
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26726por Khaligh, Fereshteh Ghahvechi, Naghian, Abdollah, Soltanbeiglou, Shadiyeh, Gholizadeh, Saber“…OBJECTIVES: Culiseta longiareolata is a cosmopolitan species and has implicated in the transmission of avian malaria, tularemia, and arboviruses. Despite the wide distribution of Cs. longiareolata in Iran, little is known about its biology and physiology. …”
Publicado 2020
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26727“…Many developing countries depend on herbal mixtures as the first line and cost-effective therapy for malaria. These mixtures with such curative tendencies may also be a source of toxicity to host cells. …”
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26728por Hagazy, Kalay, Sibhat, Gereziher G., Karim, Aman, Tekulu, Gebretsadkan H., Periasamy, Gomathi, Hiben, Mebrahtom G.“…Peter's 4-day suppressive test was used to determine the CONCLUSION: The extracts of M. dianthera leaves showed promising antimalarial activity, with no sign of toxicity and therefore may support its traditional use for the treatment of malaria.M. dianthera leaves were extracted with 80% methanol and dried. …”
Publicado 2020
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26729por Uneke, Chigozie Jesse, Sombie, Issiaka, Uro-Chukwu, Henry Chukwuemeka, Johnson, Ermel“…RESULTS: EQUIST profile analysis showed that the number of under-five deaths was considerably higher among the poorest and rural population in Nigeria, and was highest in North-West region. Neonatal causes, malaria, pneumonia and diarrhoea were responsible for most of the under-five deaths. …”
Publicado 2019
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26730por Savadogo, Hamidou, Coulibaly, Gérard, Bandaogo, Viviane, Kaboré, Aïssata, Dao, Lassina, Kaboret, Sonia, Ouédraogo-Yugbaré, Solange Odile, Kouéta, Fla, Yé, Diarra“…The main suspected causes of hemoglobinuria were: severe malaria, bacterial and viral infections, G6PD deficiency, biliary haemoglobinuric fever. …”
Publicado 2019
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26731“…BACKGROUND: Malaria is among the leading causes of mortality and morbidity. …”
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26732por Biswal, Manisha, Zaman, Kamran, Suri, Vikas, Gopi, Srikanth, Kumar, Abhay, Gopi, T., Vig, Shashi, Sharma, Navneet, Bhalla, Ashish“…Standard investigations for common pathogens causing AFI in India (malaria, dengue, scrub typhus, leptospirosis and enteric fever) were carried out. …”
Publicado 2020
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26733por Tardivo, S, Zenere, A, Moretti, F, Marchiori, F, Berti, D, Migliorini, M, Tomasi, A, Ferrari, S, Tognon, F, Napoletano, G, Rossanese, A“…The items with the highest scores were insect bites, gastrointestinal disorders and malaria. The mean scores were significantly lower after the travel for all items but one. …”
Publicado 2019
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26734por Lubiana, Pedro, Bouws, Philip, Roth, Lisa Katharina, Dörpinghaus, Michael, Rehn, Torben, Brehmer, Jana, Wichers, Jan Stephan, Bachmann, Anna, Höhn, Katharina, Roeder, Thomas, Thye, Thorsten, Gutsmann, Thomas, Burmester, Thorsten, Bruchhaus, Iris, Metwally, Nahla Galal“…Our results clearly underline the complexity of the IE-receptor interaction and the importance of knobs for the survival of the parasite at fever temperatures, and lead us to propose a new hypothesis that could open up new strategies for the treatment of malaria.…”
Publicado 2020
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26735por Huang, Yi-Shu, Ogbechi, Joy, Clanchy, Felix I., Williams, Richard O., Stone, Trevor W.“…Kynurenine involvement may account for the protection afforded to animals with cerebral malaria and trypanosomiasis when they are treated with an inhibitor of kynurenine-3-monoxygenase (KMO). …”
Publicado 2020
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26736por Frei, Angelo, Zuegg, Johannes, Elliott, Alysha G., Baker, Murray, Braese, Stefan, Brown, Christopher, Chen, Feng, G. Dowson, Christopher, Dujardin, Gilles, Jung, Nicole, King, A. Paden, Mansour, Ahmed M., Massi, Massimiliano, Moat, John, Mohamed, Heba A., Renfrew, Anna K., Rutledge, Peter J., Sadler, Peter J., Todd, Matthew H., Willans, Charlotte E., Wilson, Justin J., Cooper, Matthew A., Blaskovich, Mark A. T.“…Metal complexes are currently in clinical development for the treatment of cancer, malaria and neurodegenerative diseases. However, only little attention has been paid to their application as potential antimicrobial compounds. …”
Publicado 2020
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26737“…More attention is devoted to such diseases as West Nile fever, malaria, dengue and chikungunya which are recently a real epidemiological threat. …”
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26738por Autran, Brigitte, Combadière, Béhazine, Launay, Odile, Legrand, Roger, Locht, Camille, Tangy, Frédéric, Verger, Pierre, Garçon, Nathalie“…The recent difficulties faced by the development of vaccines against malaria, tuberculosis or AIDS illustrate the necessity of moving beyond classical recipes and of elaborating new vectors and new adjuvants, of better understanding the heterogeneity of vaccine immunity and of developing alternative routes of immunization. …”
Publicado 2017
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26739por Amlabu, Emmanuel, Ilani, Philip, Opoku, Grace, Nyarko, Prince B., Quansah, Evelyn, Thiam, Laty G., Anim, Manfred, Ayivor-Djanie, Reuben, Akuh, Ojo-ajogu, Mensah-Brown, Henrietta, Rayner, Julian C., Awandare, Gordon A.“…Using the soluble recombinant PfATRP in a screen of plasma samples revealed that malaria-infected children have naturally acquired PfATRP-specific antibodies.…”
Publicado 2020
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26740por Aruoma, Okezie I.“…Free-radical mechanisms have been implicated in the pathology of several human diseases, including cancer, atherosclerosis, malaria, and rheumatoid arthritis and neurodegenerative diseases. …”
Publicado 1998
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