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  1. 26781
    “…Febrile illnesses, such as malaria and pneumonia, are among the most common causes of mortality in children younger than 5 years in Uganda outside of the neonatal period. …”
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    Factors Motivating Traditional Healer versus Biomedical Facility Use for Treatment of Pediatric Febrile Illness: Results from a Qualitative Study in Southwestern Uganda
  2. 26782
    por Adeleke, O., Balogun, F.M.
    Publicado 2019
    “…Descriptive statistics and Chisquare test at α=0.05 were used for data analysis. RESULTS: Perceived malaria (52.4%), acne (36.2%), menstrual pain (17.0%) and depression (3.0%) were the common health problems adolescents sought health care for. …”
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    PERCEPTION OF IN-SCHOOL ADOLESCENTS ABOUT ADOLESCENTFRIENDLY CHARACTERISTICS OF HEALTHCARE SERVICES RECEIVED IN IBADAN METROPOLIS, NIGERIA
  3. 26783
    “…Asexual proliferation of the Plasmodium parasites that cause malaria follows a developmental program that alternates non-canonical intraerythrocytic replication with dissemination to new host cells. …”
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    Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes
  4. 26784
    “…Piliostigma thonningii is traditionally used for the management of inflammation, malaria fever, rheumatism, and insanity, among other diseases caused by a disturbed redox state in the body. …”
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    In Vitro Antioxidant Activities of the Aqueous and Methanolic Stem Bark Extracts of Piliostigma thonningii (Schum.)
  5. 26785
    “…DISCUSSION: Chloroquine and hydroxychloroquine are aminoquinoline derivatives widely used in the treatment of rheumatologic diseases including systemic lupus erythematosus and rheumatoid arthritis as well as for malaria prophylaxis. In early 2020, anecdotal reports and preliminary data suggested utility of hydroxychloroquine in attenuating viral loads and symptoms in patients with SARS-CoV-2 infection. …”
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    Acute chloroquine and hydroxychloroquine toxicity: A review for emergency clinicians
  6. 26786
    “…We have previously shown that a fungus from genus Trichoderma can be used for treating cerebral malaria in mouse models and inhibit biofilm formation. …”
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    Ethanolic Extract of the Fungus Trichoderma asperelloides Induces Ultrastructural Effects and Death on Leishmania amazonensis
  7. 26787
    “…In this review we discuss the beneficial or deleterious effects of various components of the purinergic signaling pathway in infectious diseases that affect the CNS, including human immunodeficiency virus (HIV-1) infection, herpes simplex virus type 1 (HSV-1) infection, bacterial meningitis, sepsis, cryptococcosis, toxoplasmosis, and malaria. We also provide a description of this signaling pathway in emerging viral infections with neurological implications such as Zika and SARS-CoV-2.…”
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    Purinergic signaling in infectious diseases of the central nervous system
  8. 26788
    “…Assessment of mefloquine plasma concentrations in treated mice showed that levels were reached which are close to serum concentrations that are achieved in humans during long-term malaria prophylaxis. Mefloquine might be applied in human AE patients as a salvage treatment. …”
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    Drug repurposing applied: Activity of the anti-malarial mefloquine against Echinococcus multilocularis
  9. 26789
    “…PURPOSE: In a dramatic reversal of longstanding trends, cancer now kills more Africans than malaria. Despite Africa’s growing cancer burden, individuals of African descent, notably those residing in Africa, remain drastically under-represented in cancer clinical trials. …”
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    Operational Strategies for Clinical Trials in Africa
  10. 26790
    “…The malaria parasite interfaces with its host erythrocyte (RBC) using a unique organelle, the parasitophorous vacuole (PV). …”
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    Contacting domains segregate a lipid transporter from a solute transporter in the malarial host–parasite interface
  11. 26791
    “…To prevent the development of resistance and reduce the underlying vectorial capacity of mosquitoes in areas targeted for malaria elimination, an effective integrated vector management strategy is needed.…”
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    Pyrethroid and Carbamate Resistance in Anopheles funestus Giles along Lake Kariba in Southern Zambia
  12. 26792
    “…Despite having reasonable safety profiles in the treatment of malaria and certain autoimmune conditions, both drugs are known to have potential cardiotoxic side effects. …”
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    Hydroxychloroquine use in COVID-19: is the risk of cardiovascular toxicity justified?
  13. 26793
    “…This review will discuss the potential impact of multi-target drug approach on various complex diseases with focus on malaria, tuberculosis (TB), diabetes and neurodegenerative diseases as the main representatives of multifactorial diseases. …”
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    Potential Impact of the Multi-Target Drug Approach in the Treatment of Some Complex Diseases
  14. 26794
    “…Emergence of resistant Plasmodium species makes drug efficacy testing a crucial part of malaria control. Here we describe a novel assay for sensitive, fast and simple drug screening via the magneto-optical detection of hemozoin, a natural biomarker formed during the hemoglobin metabolism of Plasmodium species. …”
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    Rapid and quantitative antimalarial drug efficacy testing via the magneto-optical detection of hemozoin
  15. 26795
    “…Nonetheless, eight disease‐specific immune mediators were identified as potential biomarkers for dengue (MIP‐1α, MCP‐1), malaria (TNF‐α), streptococcal and meningococcal (eotaxin, GRO‐α, RANTES, SDF‐1α and PIGF‐1) infections, with high specificity and sensitivity profiles. …”
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    Systematic analysis of disease‐specific immunological signatures in patients with febrile illness from Saudi Arabia
  16. 26796
    “…The larvicidal activity of the bags treated with pectin-cedar wood nanocapsules was assessed against malaria vector, Anopheles culicifacies and 98% mortality was recorded till 4 weeks, this suggests its potential and hassle free applications in controlling mosquito vector.…”
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    Impregnation of pectin-cedarwood essential oil nanocapsules onto mini cotton bag improves larvicidal performances
  17. 26797
    “…Anti-viral infection. Anti-malaria and anti-systemic lupus erythematosus (SLE). 2. …”
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    The importance of vitamin d metabolism as a potential prophylactic, immunoregulatory and neuroprotective treatment for COVID-19
  18. 26798
    “…Besides, the fact that obtaining vaccines faster through deliberate infection studies of healthy people has greater benefits than risks, has been demonstrated by obtaining other vaccines in other historical pandemics such as: smallpox, influenza, malaria, typhoid fever, Dengue fever and Zika. CONCLUSIONS: One possibility to shorten the time required for the development of COVID-19 vaccines is to reduce clinical phases II and III by using human challenge studies through eliberate infection of healthy volunteers with SARS-CoV-2 after administration of the candidate vaccine. …”
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    COVID-19 vaccines: ethical framework concerning human challenge studies
  19. 26799
    “…It has been suggested that chloroquine (CQ) and hydroxychloroquine (HCQ), which were primarily employed as prophylaxis and treatment for malaria, could be used to treat COVID-19. CQ and HCQ may be potential inhibitors of SARS-CoV-2 entry into host cells, which are mediated via the angiotensin-converting enzyme 2 (ACE2), and may also inhibit subsequent intracellular processes which lead to COVID-19, including damage to the cardiovascular (CV) system. …”
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    The Effects of Chloroquine and Hydroxychloroquine on ACE2-Related Coronavirus Pathology and the Cardiovascular System: An Evidence-Based Review
  20. 26800
    por Habte, Getu, Assefa, Solomon
    Publicado 2020
    “…BACKGROUND: The alarming spread of parasite resistance to current antimalarial agents is threatening malaria controlling efforts. This, consequently, urged the scientific community to discover novel antimalarial drugs. …”
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    In Vivo Antimalarial Activity of Crude Fruit Extract of Capsicum frutescens Var. Minima (Solanaceae) against Plasmodium berghei-Infected Mice
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