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  1. 26921
    “…Nα-2-thiophenoyl-d-phenylalanine-2-morpholinoanilide (MMV688845, IUPAC: N-(1-((2-morpholinophenyl)amino)-1-oxo-3-phenylpropan-2-yl)thiophene-2-carboxamide) from the Pathogen Box(®) library (Medicines for Malaria Ventures, MMV) is a promising lead compound for antimycobacterial drug development. …”
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    Racemization-free synthesis of Nα-2-thiophenoyl-phenylalanine-2-morpholinoanilide enantiomers and their antimycobacterial activity
  2. 26922
    “…Annona muricata and Khaya grandifoliola are ethnomedicinally used for the treatment of malaria and have been experimentally shown to have an anti-plasmodial effect, but the mechanisms involved are not fully understood. …”
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    Annona muricata Linn and Khaya grandifoliola C.DC. Reduce Oxidative Stress In Vitro and Ameliorate Plasmodium berghei-Induced Parasitemia and Cytokines in BALB/c Mice
  3. 26923
    “…BACKGROUND: Phlebotomine sand flies are prominent vectors of Leishmania parasites that cause leishmaniasis, which comes second to malaria in terms of parasitic causative fatalities globally. …”
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    Chemical control and insecticide resistance status of sand fly vectors worldwide
  4. 26924
    “…Despite this, histopathological chorioamnionitis, and funisitis (when examined) were commonly observed in preterm birth complicated by confirmed bacterial or viral, but not parasitic, infection. The presence of malaria parasites but not pigment in placenta was reported to increase the risk of PTB, but this finding was inconclusive. …”
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    Placental histopathology in preterm birth with confirmed maternal infection: A systematic literature review
  5. 26925
    “…Standard questionnaire in assessing the household socio-economic status adapted from standard surveys, such as Nigeria Health and Demographic Survey and Malaria Indicator Survey, was administered on the household heads of each household every 2 years to monitor socio-economic advancement of the households. …”
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    Health and Demographic Surveillance System: A Potential Tool for Solving Challenges Associated with Epidemic Surveillance and Social Protection Scheme for COVID-19 Pandemic Response in Nigeria
  6. 26926
    por Xiong, Ye, Huang, Jianrong
    Publicado 2021
    “…Artemisinin and its derivatives belong to a family of drugs approved for the treatment of malaria with known clinical safety and efficacy. In addition to its anti-malarial effect, artemisinin displays anti-viral, anti-inflammatory, and anti-cancer effects in vivo and in vitro. …”
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    Anti-malarial drug: the emerging role of artemisinin and its derivatives in liver disease treatment
  7. 26927
    “…Additionally, the resurgence and emergence of old and new diseases such as cholera, chikungunya, malaria, HIV/AIDS as indicators of inadequate health services were most likely during political turmoil. …”
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    An Overview of Healthcare Systems in Comoros: The Effects of Two Decades of Political Instability
  8. 26928
    “…In our preferred empirical model with household fixed effects, we find that health worker absenteeism reduces the odds that a patient seeks care in the public sector (OR = 0.65, 95% CI = 0.44–0.95) and receives malaria testing (OR = 0.73, 95% CI = 0.53–0.99) and increases the odds of paying out-of-pocket for treatment (OR = 1.41, 95% CI = 1.10–1.80). …”
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    The impact of health worker absenteeism on patient health care seeking behavior, testing and treatment: A longitudinal analysis in Uganda
  9. 26929
    “…Climate change is one of the critical determinants affecting life cycles and transmission of most infectious agents, including malaria, cholera, dengue fever, hand, foot, and mouth disease (HFMD), and the recent Corona-virus pandemic. …”
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    Effect of climate factors on the incidence of hand, foot, and mouth disease in Malaysia: A generalized additive mixed model
  10. 26930
    “…The highly conserved Plasmodium falciparum cysteine-rich protective antigen (PfCyRPA) is a key target for next-generation vaccines against blood-stage malaria. PfCyRPA constitute the core of a ternary complex, including the reticulocyte binding-like homologous protein 5 (PfRh5) and the Rh5-interacting protein (PfRipr), and is fundamental for merozoite invasion of erythrocytes. …”
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    Strain-Dependent Inhibition of Erythrocyte Invasion by Monoclonal Antibodies Against Plasmodium falciparum CyRPA
  11. 26931
    “…Blocking lactate export in the parasitic protozoan Plasmodium falciparum is a novel strategy to combat malaria. We discovered small drug-like molecules that inhibit the sole plasmodial lactate transporter, PfFNT, and kill parasites in culture. …”
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    Fluorescence Cross-Correlation Spectroscopy Yields True Affinity and Binding Kinetics of Plasmodium Lactate Transport Inhibitors
  12. 26932
    “…Background: Artemisinin-based combination therapy (ACT) was recommended to treat uncomplicated falciparum malaria. Unlike the situation in Asia where resistance to ACT has been reported, artemisinin resistance has not yet emerged in Africa. …”
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    Prevalence of Mutations in the pfcoronin Gene and Association with Ex Vivo Susceptibility to Common Quinoline Drugs against Plasmodium falciparum
  13. 26933
    “…Insect-transmitted NTDs include, but are not limited to, malaria, dengue and lymphatic filariasis. Control measures for these disease, are often ignored because of the associated cost. …”
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    Challenges in the control of neglected insect vector diseases of human importance in the Anglo-Caribbean
  14. 26934
    “…INTRODUCTION: Dengue and Malaria are the most important mosquito-borne viral diseases affecting humans. …”
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    Optimal bang-bang control for variable-order dengue virus; numerical studies()
  15. 26935
    “…In Africa, medicinal plants are commonly used to treat malaria and other diseased conditions. The ethanolic leaf and twig extract of Faurea speciosa has been shown to possess promising antiplasmodial properties. …”
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    In Vivo Antiplasmodial Activity and Toxicological Analyses of the Ethanolic Leaf and Twig Extract of Faurea speciosa Welw. (Proteaceae)
  16. 26936
    “…Koenig is traditionally used to treat various diseases including diarrhea, cholera, dysentery, fever, malaria, and viral infections, among others. To summarize critically the taxonomy, ethnomedicinal, phytochemistry, and pharmacological activities of X. granatum, information was collected from different databases. …”
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    Ethnomedicinal Use, Phytochemistry, and Pharmacology of Xylocarpus granatum J. Koenig
  17. 26937
    “…Public health priority programs that have faced drug-resistance challenges associated with diseases, such as tuberculosis, HIV, and malaria, have given less attention to risks attributable to the COVID-19 pandemic. …”
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    Antimicrobial resistance: A challenge awaiting the post-COVID-19 era
  18. 26938
    “…The magnitude and functional patterns of intraspecific transcriptional variation in the anophelines, including those of sex-biased genes underlying sex-specific traits relevant for malaria transmission, remain understudied. As a result, how changes in expression levels drive adaptation in these species is poorly understood. …”
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    Intraspecific Transcriptome Variation and Sex-Biased Expression in Anopheles arabiensis
  19. 26939
    “…It indicates possible widespread among malaria vector species and warrants investigations into the symbiont’s diversity across sub-Saharan Africa.…”
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    Microsporidia MB is found predominantly associated with Anopheles gambiae s.s and Anopheles coluzzii in Ghana
  20. 26940
    “…Hydroxychloroquine (HCQ), also known by its trade name Plaquenil®, has been used for over 50 years as a treatment for malaria, systemic lupus erythematosus, and rheumatoid arthritis. …”
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    Risk versus Benefit of Using Hydroxychloroquine to Treat Patients with COVID-19
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