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26941“…E. globulus leaf has been used in the traditional management of malaria in different countries, including Ethiopia. …”
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26942por Cela, Marta, Théobald-Dietrich, Anne, Rudinger-Thirion, Joëlle, Wolff, Philippe, Geslain, Renaud, Frugier, Magali“…Malaria is a life-threatening and devastating parasitic disease. …”
Publicado 2021
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26943por Schlott, Anja C., Knuepfer, Ellen, Green, Judith L., Hobson, Philip, Borg, Aaron J., Morales-Sanfrutos, Julia, Perrin, Abigail J., Maclachlan, Catherine, Collinson, Lucy M., Snijders, Ambrosius P., Tate, Edward W., Holder, Anthony A.“…We have combined chemical biology and genetic modification approaches to investigate the importance of protein myristoylation in the human malaria parasite, Plasmodium falciparum. Parasite treatment during schizogony in the last 10 to 15 hours of the erythrocytic cycle with IMP-1002, an inhibitor of N-myristoyl transferase (NMT), led to a significant blockade in parasite egress from the infected erythrocyte. …”
Publicado 2021
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26944por Li, Xiaobo, Hu, Jiaoting, Yuan, Yueming, Wang, Yunhan, Yuan, Zheng, Liu, Ruidong, Zhang, Shouya, Xu, Zhiyong, Wang, Qi, Xu, Qin, Ru, Li, Song, Jianping“…Artemisinin-hydroxychloroquine sulfate tablets (AH) are relatively inexpensive and a novel combination therapy for the treatment of all forms of malaria, especially aminoquinine drug-resistant strains of P. falciparum. …”
Publicado 2021
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26945por Kumar, Sudhir, Haile, Meseret T., Hoopmann, Michael R., Tran, Linh T., Michaels, Samantha A., Morrone, Seamus R., Ojo, Kayode K., Reynolds, Laura M., Kusebauch, Ulrike, Vaughan, Ashley M., Moritz, Robert L., Kappe, Stefan H. I., Swearingen, Kristian E.“…Gametocytes of the malaria parasite Plasmodium are taken up by the mosquito vector with an infectious blood meal, representing a critical stage for parasite transmission. …”
Publicado 2021
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26946por Hart, Kevin J., Power, B. Joanne, Rios, Kelly T., Sebastian, Aswathy, Lindner, Scott E.“…Productive transmission of malaria parasites hinges upon the execution of key transcriptional and posttranscriptional regulatory events. …”
Publicado 2021
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26947por Hocking, Lucy, George, Jenny, Broberg, Eeva K., Struelens, Marc J., Leitmeyer, Katrin C., Deshpande, Advait, Parkinson, Sarah, Francombe, Joe, Morley, Katherine I., de Carvalho Gomes, Helena“…POCT is commonly available for influenza, HIV/AIDS, Legionnaires' disease and malaria, where it is used in at least half of EU/EEA countries. …”
Publicado 2021
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26948Challenges and Solutions in translating sepsis guidelines into practice in resource-limited settings“…Specifically, strengthening pediatric intensive care units (PICU) services can effectively treat the life-threatening complications of common diseases, such as diarrhoea, respiratory infections, severe malaria, and dengue, thereby improving the quality of pediatric care overall without the need for expensive interventions. …”
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26949por Schumann, Robin, Bischoff, Eileen, Klaus, Severina, Möhring, Sophie, Flock, Julia, Keller, Sandro, Remans, Kim, Ganter, Markus, Deponte, Marcel“…Decreased susceptibilities of the human malaria parasite Plasmodium falciparum towards the endoperoxide antimalarial artemisinin are linked to mutations of residue C580 of PfKelch13, a homologue of the redox sensor Keap1 and other vertebrate BTB-Kelch proteins. …”
Publicado 2021
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26950por Banerjee, Sitikantha, Selvaraj, Kalaiselvi, Bandyopadhyay, Kajari, Firdous Khan, Mubashshera, Bisen, Tikesh, Deshmukh, Pradeep“…Services like distribution of conventional contraceptives, testing for malaria, urine albumin/sugar, haemoglobin estimation, screening for diabetes and hypertension, sputum collection, and qualitative iodine test kits are not available in any of the UHND sessions. …”
Publicado 2021
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26951“…These in turn, infect red blood cells and cause malaria symptoms. To initiate a productive infection, sporozoites must exit the circulation by traversing the blood lining of the liver vessels after which they infect hepatocytes with unique specificity. …”
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26952por Costanza, Alessandra, Placenti, Valeria, Amerio, Andrea, Aguglia, Andrea, Serafini, Gianluca, Amore, Mario, Macchiarulo, Elena, Branca, Francesco, Merli, Roberto, Bondolfi, Guido, Nguyen, Khoa Dinh“…The case was followed by a mini-review of the heterogeneous scientific literature on the hypothetical association between neuropsychiatric symptoms, with a focus on SI and suicidal behavior (SB, including SA and death by suicide), when CQ and HCQ are used in COVID-19, rheumatologic diseases, and malaria settings. Considering the anti-inflammatory properties of CQ and HCQ and the implications for neuroinflammation in suicide pathogenesis, the possible increase in suicide risk caused by these medications appears paradoxical and suggests that other underlying pathological trajectories might account for this eventuality. …”
Publicado 2021
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26953por Raele, Donato Antonio, Panzarino, Ginevra, Sarcinelli, Giuseppe, Cafiero, Maria Assunta, Maria Tunzi, Anna, Dellù, Elena“…Three teeth from each individual were collected and sent to the Istituto Zooprofilattico Sperimentale di Puglia e Basilicata to study infectious diseases such as malaria, plague, tuberculosis, epidemic typhus and Maltese fever (Brucellosis), potentially related to the lack of inspection of the bodies during burial procedures. …”
Publicado 2021
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26954por Razak, Raimalynah Abd, Suzery, Meiny, Razali, Rafida, Amin, Zarina, Mokhtar, Ruzaidi Azli Mohd, Lee, Ping Chin, Budiman, Cahyo“…Proteolytic subunit of the caseinolytic protease system of Plasmodium knowlesi (Pk-ClpP; EC 3.4.21.92) is considered a viable target for antimalarial drug development to eradicate P. knowlesi malaria infection in Malaysia and Southeast Asian region. …”
Publicado 2021
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26955por Inbar, Ehud, Eappen, Abraham G., Alford, Robert T., Reid, William, Harrell, Robert A., Hosseini, Maryam, Chakravarty, Sumana, Li, Tao, Sim, B. Kim Lee, Billingsley, Peter F., Hoffman, Stephen L.“…PfSPZ Vaccine against malaria is composed of Plasmodium falciparum (Pf) sporozoites (SPZ) manufactured using aseptically reared Anopheles stephensi mosquitoes. …”
Publicado 2021
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26956por Moses, Arinaitwe, Adriko, Moses, Kibwika, Brian, Tukahebwa, Edridah M., Faust, Christina L., Lamberton, Poppy H. L.“…Schistosomiasis is the second most important parasitic infection after malaria in terms of its socioeconomic impact and is endemic in 78 countries. …”
Publicado 2021
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26957“…The aim of this review article focuses mainly on the theranostic applications of microneedles in various medical conditions such as malaria, glaucoma, cancer, etc. GRAPHICAL ABSTRACT: [Image: see text]…”
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26958por Chavhan, Smita S., Kashyap, Vandana, Gokhale, Chinmay N, Adsul, Balkrishna B., Gomare, Mangala, Kumbhar, Maharudra, Kadam, Neelam, Dhikale, Prasad T., Kinge, Kirti V.“…BACKGROUND: The onset of monsoons in Mumbai poses an additional health disease burden in the form of rising vector-borne and water-borne diseases such as dengue, malaria, leptospirosis, hepatitis, typhoid, chikungunya, and acute gastroenteritis. …”
Publicado 2021
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26959por Orabueze, Ifeoma Celestina, Uzor, Sarah Chiamaka, Ndiaye, Bou, Uba, Desire, Ota, Duncan Azubuike., Agbedahusi, Joseph“…MATERIALS AND METHODS: The ability of SL leaf extract to suppress the growth of malaria parasites in early (suppressive) and established (curative) infections was established using animal models. …”
Publicado 2021
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26960por Woldeyohanins, Alem Endeshaw, Kasahun, Asmamaw Emagn, Demeke, Chilot Abiyu, Kifle, Zemene Demelash“…Availability and utilization of priority medicines for the management of antiretroviral infections, Vitamin A deficiency, malaria, and diarrheal cases were high, whereas availability and utilization of suggested medication for neonatal sepsis were very low. …”
Publicado 2021
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