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26981“…Emergence and spread of malaria vectors resistant to the available insecticides required a new and efficacious insecticide. …”
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26982por Bandoh, Delia A, Baidoo, Abraham, Noora, Charles L, Quartey, Sally, Frimpong, Joseph A, Kenu, Ernest“…FUNDING: The COVID-19 outbreak response and writing workshop by the Ghana Field Epidemiology and Laboratory Training Programme (G.F.E.L.T.P.) was supported with funding from President Malaria Initiative – C.D.C., and Korea International Cooperation Agency (on C.D.C. …”
Publicado 2021
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26983Integration of multiple geospatial applications and intelligence for responding to COVID-19 in Ghanapor Owusu, Alex B, Afagbedzi, Seth K, Bandoh, Delia A, Frimpong, Joseph A, Kissiedu, Isaac N, Aikins, Ben E, Hinneh, Richmond, Kenu, Ernest“…FUNDING: The development and deployment of the application, COVID-19 pandemic response and writing workshop by the Ghana Field Epidemiology and Laboratory Training Programme (GFELTP) was supported with funding from President Malaria Initiative – CDC, and Korea International Cooperation Agency (on CDC CoAg 6NU2GGH001876) through AFENET and the United States Agency for International Development (USAID) through Results for Development (R4D).…”
Publicado 2021
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26984por Ekasari, Wiwied, Mahardiani, Anisah, Putri, Nindya T., Wahyuni, Tutik S., Arwati, Heny“…Currently, the presence of antimalarial drug resistance has become a major obstacle in the treatment of malaria. To overcome the problem, a series of studies are needed to find new antimalarial drugs from plants. …”
Publicado 2022
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26985por Shanley, Harrison T., Taki, Aya C., Byrne, Joseph J., Jabbar, Abdul, Wells, Tim N. C., Samby, Kirandeep, Boag, Peter R., Nguyen, Nghi, Sleebs, Brad E., Gasser, Robin B.“…With a focus on discovering new anthelmintic entities, we screened 400 chemically diverse compounds within the ‘Pandemic Response Box’ (from Medicines for Malaria Venture, MMV) for activity against H. contortus and its free-living relative, Caenorhabditis elegans—a model organism. …”
Publicado 2022
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26986por Ajogbasile, Fehintola V., Oluniyi, Paul E., Kayode, Adeyemi T., Akano, Kazeem O., Adegboyega, Benjamin B., Philip, Courage, Ogbulafor, Nnenna, Okafor, Henrietta U., Oguche, Stephen, Wammanda, Robinson D., Mokuolu, Olugbenga A., Folarin, Onikepe A., Happi, Christian T.“…Accurate assessment and monitoring of the Plasmodium falciparum Kelch 13 (pfk13) gene associated with artemisinin resistance is critical to understand the emergence and spread of drug-resistant parasites in malaria-endemic regions. In this study, we evaluated the genomic profile of the pfk13 gene associated with artemisinin resistance in P. falciparum in Nigerian children by targeted sequencing of the pfk13 gene. …”
Publicado 2022
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26987por Melamed, Daniel, Nov, Yuval, Malik, Assaf, Yakass, Michael B., Bolotin, Evgeni, Shemer, Revital, Hiadzi, Edem K., Skorecki, Karl L., Livnat, Adi“…The HBB region of interest (ROI) includes the site of the hemoglobin S (HbS) mutation, which protects against malaria, is common in Africa, and has served as a classic example of adaptation by random mutation and natural selection. …”
Publicado 2022
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26988por Mariam, Solomon H.“…Several hypotheses have been forwarded as reasons for this and include warmer weather conditions, vaccination with BCG (i.e., trained immunity), and previous malaria infection. From genetics or metabolic points of view, it has been proposed that most African populations could be protected to some degree because they lack some genetic susceptibility risk factors or have low-level expression of allelic variants, such as ACE2 and TMPRSS2 that are thought to be involved in increased infection risk or disease severity. …”
Publicado 2022
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26989por Meng, Ying, Liang, Yu, Liao, Baosheng, He, Wenrui, Liu, Qianwen, Shen, Xiaofeng, Xu, Jiang, Chen, Shilin“…Artemisinin, which can only be obtained from Artemisia annua L., is the most effective therapeutic drug for malaria without serious side effects. This study identified and analyzed LOX gene family members in the A. annua genome at the chromosomal level. …”
Publicado 2022
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26990por Dietrich, Melanie H, Chan, Li-Jin, Adair, Amy, Boulet, Coralie, O'Neill, Matthew T, Tan, Li Lynn, Keremane, Sravya, Mok, Yee-Foong, Lo, Alvin W, Gilson, Paul, Tham, Wai-Hong“…Future studies using these inhibitory nanobodies will be useful to determine the functional role of these two 6-cys proteins in malaria parasites.…”
Publicado 2022
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26991por Baye, Kaleab, Mekonnen, Dawit, Choufani, Jowel, Yimam, Seid, Bryan, Elizabeth, Grifith, Jeffrey K., Ringler, Claudia“…Irrigators were more likely to meet the MDDW than women from non‐irrigating households (p < 0.05). No cases of malaria were reported from the three rounds of screening. …”
Publicado 2021
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26992por Tari, Rachida Moussa, Diallo, Aboudoulatif, Kouame, Emmanuelle, Assogba, Phénix, Badjabaissi, Essotolom, Povi, Lawson-Evi, Bakoma, Batomayena, Potchoo, Yao, Tona, Kokou“…BACKGROUND: The sulfadoxine-pyrimethamine combination is a product used in the intermittent preventive treatment (IPT) of malaria in pregnant women in our country. To date, there is very little data on the teratogenic effect of this product. …”
Publicado 2022
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26993por Sparkes, Susan P, Campos Rivera, Paola Abril, Jang, Hyobum, Marten, Robert, Rajan, Dheepa, Robb, Alastair, Shroff, Zubin Cyrus“…LOCAL SETTING: We provide examples from across a range of World Health Organization areas of work, including participatory governance, health financing, health taxes, malaria prevention and control, capacity-building and direct country support. …”
Publicado 2022
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26994por Kouakou, Yobouet Ines, Omorou, Roukayatou, Said, Ibrahim Bin, Lavoignat, Adeline, Bonnot, Guillaume, Bienvenu, Anne-Lise, Picot, Stéphane“…Artesunate is the current most potent antimalarial drug widely used for the treatment of malaria. Considering the emergence of artemisinin resistance, several situations may require a simple method for artesunate quantification. …”
Publicado 2022
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26995por Zhang, Rui, Chen, Xi, Zuo, Wenjie, Ji, Zhenjun, Qu, Yangyang, Su, Yamin, Yang, Mingming, Zuo, Pengfei, Ma, Genshan, Li, Yongjun“…Gene Set Enrichment Analysis (GSEA) analysis of Kyoto Encyclopedia of Genes and Genomes (KEGG) showed that malaria, IL-17 signaling pathway, and complement and coagulation cascades were significantly enriched. …”
Publicado 2022
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26996por Stagliano, David R., Kuo, Huai-Ching, Fraser, Jamie A., Mitra, Indrani, Garges, Eric C., Riddle, Mark S., Tribble, David R., Hickey, Patrick W.“…A cohort of 80,214 adult travelers receiving malaria chemoprophylaxis for less than 6 weeks of travel were identified within the U.S. …”
Publicado 2022
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26997por Kanunfre, Kelly Aparecida, Rocha, Mussya Cisotto, Malta, Maíra Barreto, de Souza, Rodrigo Medeiros, Castro, Marcia Caldas, Boscardin, Silvia Beatriz, Souza, Higo Fernando Santos, Witkin, Steven S., Cardoso, Marly Augusto, Okay, Thelma Suely“…Negative CHIKV serology was associated with being positive for DENV antibodies and having had malaria during pregnancy. These findings showed that there was already a silent circulation of CHIKV in this Amazon region before the first outbreak of chikungunya fever. …”
Publicado 2022
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26998“…The 1‐Cys peroxiredoxin 5 homolog PfAOP from the malaria parasite Plasmodium falciparum is an established model enzyme for glutathione/glutaredoxin‐dependent peroxiredoxins. …”
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26999por Mogire, Reagan M., Muriuki, John Muthii, Morovat, Alireza, Mentzer, Alexander J., Webb, Emily L., Kimita, Wandia, Ndungu, Francis M., Macharia, Alex W., Cutland, Clare L., Sirima, Sodiomon B., Diarra, Amidou, Tiono, Alfred B., Lule, Swaib A., Madhi, Shabir A., Prentice, Andrew M., Bejon, Philip, Pettifor, John M., Elliott, Alison M., Adeyemo, Adebowale, Williams, Thomas N., Atkinson, Sarah H.“…To evaluate associations between vitamin D and iron status we measured markers of iron status, inflammation, malaria parasitemia, and 25-hydroxyvitamin D (25(OH)D) concentrations in 4509 children aged 0.3 months to 8 years living in Kenya, Uganda, Burkina Faso, The Gambia, and South Africa. …”
Publicado 2022
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27000por Elehinafe, Francis Boluwaji, Okedere, Oyetunji Babatunde, Adesanmi, Adewole Johnson, Jimoh, Eniola Mistura“…Mosquito coils are commonly burnt in indoor environments to drive away mosquitoes which are vectors for malaria parasites. The levels of carbon monoxide (CO) emitted and human health implications during smoldering of 5 different brands of mosquito coils commonly used in Nigeria were investigated in 4 microenvironments of different sizes. …”
Publicado 2022
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