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  1. 27041
    “…The sexual stage gametocytes of the malaria parasite, Plasmodium falciparum, adopt a falciform (crescent) shape driven by the assembly of a network of microtubules anchored to a cisternal inner membrane complex (IMC). …”
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    Repurposing the mitotic machinery to drive cellular elongation and chromatin reorganisation in Plasmodium falciparum gametocytes
  2. 27042
    “…The phylum Apicomplexa includes thousands of species of unicellular parasites that cause a wide range of human and animal diseases such as malaria and toxoplasmosis. To infect, the parasite must first initiate active movement to disseminate through tissue and invade into a host cell, and then cease moving once inside. …”
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    An apical protein, Pcr2, is required for persistent movement by the human parasite Toxoplasma gondii
  3. 27043
    “…BACKGROUND: While malaria and neglected tropical disease (NTD) morbidity and mortality rates among children <5 years old have decreased through public health efforts in the United Republic of Tanzania, associations between household environments and disease outcomes are relatively unknown. …”
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    Household profiles of neglected tropical disease symptoms among children: A latent class analysis of built-environment features of Tanzanian households using the Demographic and Health Survey
  4. 27044
    “…Independent of the preexposure of donors to malaria parasites, non-VDJ inserts were detected in 80% of individuals at frequencies of 1 in 10(4) to 10(5) B cells. …”
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    Different classes of genomic inserts contribute to human antibody diversity
  5. 27045
    “…Although fungal infections remain in the shadow of public awareness, total attributable annual deaths are similar to, or exceeds, global mortalities due to malaria, tuberculosis or HIV. The impact of fungal infections has been exacerbated by the steady rise of antifungal drug resistant strains and species which reflects the widespread use of antifungals for prophylaxis and therapy, and in the case of azole resistance in Aspergillus, has been linked to the widespread agricultural use of antifungals. …”
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    The importance of antimicrobial resistance in medical mycology
  6. 27046
    “…This technology of vaccine manufacturing has previously been used in many human clinical trials conducted for adenoviral vector-based vaccines against different infectious agents, including Ebola virus, Zika virus, HIV, and malaria. In this paper, we have a review of nucleic acid-based vaccines that are passing their phase 3 and 4 clinical trials and discuss their efficiency and adverse effects.…”
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    Viral vector and nucleic acid vaccines against COVID-19: A narrative review
  7. 27047
    “…CONTEXT: Kniphofia (Asphodelaceae) is found mainly in South Africa and Tropical Africa. Malaria, hepatitis B, blood purifier, cancer, eczema, and female infertility have all been traditionally treated using this genus. …”
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    A comprehensive review of the ethnomedicine, phytochemistry, pharmacological activities of the genus Kniphofia
  8. 27048
    “…Howler monkey populations in professional care offer a window to investigate susceptibility to diseases in this species such as yellow fever (YF) and malaria, plus a myriad of endoparasite phyla, as well as vector-borne diseases such as Chagas disease and leishmaniasis. …”
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    Integrated approaches to howler monkey (Alouatta spp.) medicine in professional care and conservation
  9. 27049
    “…Malaria transmission-blocking vaccines (TBVs) aim to elicit human antibodies that inhibit sporogonic development of Plasmodium falciparum in mosquitoes, thereby preventing onward transmission. …”
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    Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses
  10. 27050
    “…One CHC (14%, 1/7) had two forms of diagnostic tests available for the detection of malaria. All CHCs lacked adequate microbiology laboratories. …”
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    Optimizing Public Health Preparedness for Highly Infectious Diseases in Central Vietnam
  11. 27051
    “…We tested our optimization on an EfficientNet-B0 as a baseline architecture and made classification tests on the CIFAR-10, Colorectal Cancer Histology, and Malaria datasets. For each dataset, our optimization achieves a saving of 76%, 89%, and 91% of the number of trainable parameters of EfficientNet-B0, while keeping its test classification accuracy.…”
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    An Enhanced Scheme for Reducing the Complexity of Pointwise Convolutions in CNNs for Image Classification Based on Interleaved Grouped Filters without Divisibility Constraints
  12. 27052
    “…The good oral bioavailability and transplacental transfer of azithromycin make this drug suitable for the treatment of sexually transmitted diseases, toxoplasmosis, and malaria. Moreover, azithromycin is useful both in the management of preterm pre-labor rupture of membranes and in the adjunctive prophylaxis for cesarean delivery. …”
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    Use of Azithromycin in Pregnancy: More Doubts than Certainties
  13. 27053
    “…The most frequently reported risk factors (i.e., reported in ≥10 studies) were previous history of PTB, underutilization of antenatal care (<4 visits), premature rupture of membrane, maternal age (≤20 or ≥35 years), inter-pregnancy interval, malaria, HIV and hypertension in pregnancy. Premature babies had high rates of hospital admissions, were at risk of poor growth and development, and were also at a high risk of morbidity and mortality. …”
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    A Scoping Review of Preterm Births in Sub-Saharan Africa: Burden, Risk Factors and Outcomes
  14. 27054
    “…This review highlights CRISPR-Cas-based molecular technologies in diagnosing several tropical diseases, namely malaria, zika, chikungunya, human immunodeficiency virus and acquired immunodeficiency syndrome (HIV-AIDS), tuberculosis (TB), and rabies.…”
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    CRISPR-Based Programmable Nucleic Acid-Binding Protein Technology Can Specifically Detect Fatal Tropical Disease-Causing Pathogens
  15. 27055
    “…Ex vivo phenotyping of P. falciparum erythrocyte invasion diversity is important in the identification and down selection of potential malaria vaccine targets. However, due to the lack of appropriate laboratory facilities in remote areas of endemic countries, direct processing of P. falciparum clinical isolates is usually not feasible. …”
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    Short-term cryopreservation and thawing have minimal effects on Plasmodium falciparum ex vivo invasion profile
  16. 27056
    “…Murine models of psoriatic disease (imiquimod) and parasite infections (malaria) exhibited shifts to memory phenotypes with repeated immune challenge. …”
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    Human and murine memory γδ T cells: Evidence for acquired immune memory in bacterial and viral infections and autoimmunity
  17. 27057
    “…Infection with Plasmodium falciparum parasites results in approximately 627,000 deaths from malaria annually. Key to the parasite’s success is their ability to invade and subsequently grow within human erythrocytes. …”
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    The Plasmodium falciparum parasitophorous vacuole protein P113 interacts with the parasite protein export machinery and maintains normal vacuole architecture
  18. 27058
    “…We screened the Medicines for Malaria Venture Pathogen Box for chemical entities that inhibit EAEC biofilm formation. …”
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    Antibiofilm agents with therapeutic potential against enteroaggregative Escherichia coli
  19. 27059
    “…The global spread of drug resistance is a major obstacle to the treatment of Plasmodium falciparum malaria. The identification of drug-resistance genes is an essential step toward solving the problem of drug resistance. …”
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    Genome-wide functional screening of drug-resistance genes in Plasmodium falciparum
  20. 27060
    “…In Western Sahelian populations, signatures of selection were detected in several other genetic regions, including pathways associated with lactase persistence, immune response, and malaria resistance. Taken together, these findings refine our current knowledge of genetic diversity, population structure, migration, admixture and adaptation of human populations in the Sahel/Savannah belt and contribute to our understanding of human history and health.…”
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    Demographic and Selection Histories of Populations Across the Sahel/Savannah Belt
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