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27341por Bachmann, Anna, Petter, Michaela, Tilly, Ann-Kathrin, Biller, Laura, Uliczka, Karin A., Duffy, Michael F., Tannich, Egbert, Bruchhaus, Iris“…Avoidance of antibody-mediated immune recognition allows parasites to establish chronic infections and enhances opportunities for transmission. The human malaria parasite Plasmodium falciparum possesses a number of multi-copy gene families, including var, rif, stevor and pfmc-2tm, which encode variant antigens believed to be expressed on the surfaces of infected erythrocytes. …”
Publicado 2012
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27342por Aguilar, Ruth, Moraleda, Cinta, Quintó, Llorenç, Renom, Montse, Mussacate, Lázaro, Macete, Eusebio, Aguilar, Josep L., Alonso, Pedro L., Menéndez, Clara“…One of the reasons for this is the commonly held view that iron supplementation increases the susceptibility to some infectious diseases including malaria. Secondly, currently used markers to diagnose iron deficiency are also modified by infections. …”
Publicado 2012
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27343por Dean, Anna S., Crump, Lisa, Greter, Helena, Hattendorf, Jan, Schelling, Esther, Zinsstag, Jakob“…Given that 78% patients had fever, brucellosis poses a diagnostic challenge in malaria-endemic areas. Significant delays in appropriate diagnosis and treatment were the result of health service inadequacies and socioeconomic factors. …”
Publicado 2012
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27344por Ibitokou, Samad, Oesterholt, Mayke, Brutus, Laurent, Borgella, Sophie, Agbowaï, Carine, Ezinmègnon, Sèm, Lusingu, John, Schmiegelow, Christentze, Massougbodji, Achille, Deloron, Philippe, Troye-Blomberg, Marita, Varani, Stefania, Luty, Adrian J. F., Fievet, Nadine“…Knowledge of the profiles of immune cells associated with the physiopathology of pregnancy-associated malaria (PAM) is scarce. We conducted a longitudinal, prospective study, both in Benin and Tanzania, including ∼1000 pregnant women in each site with systematic follow-up at scheduled antenatal visits until delivery. …”
Publicado 2012
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27345por Francia, Maria E., Jordan, Carly N., Patel, Jay D., Sheiner, Lilach, Demerly, Jessica L., Fellows, Justin D., de Leon, Jessica Cruz, Morrissette, Naomi S., Dubremetz, Jean-François, Striepen, Boris“…Apicomplexa are intracellular parasites that cause important human diseases including malaria and toxoplasmosis. During host cell infection new parasites are formed through a budding process that parcels out nuclei and organelles into multiple daughters. …”
Publicado 2012
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27346por Góngora-Castillo, Elsa, Childs, Kevin L., Fedewa, Greg, Hamilton, John P., Liscombe, David K., Magallanes-Lundback, Maria, Mandadi, Kranthi K., Nims, Ezekiel, Runguphan, Weerawat, Vaillancourt, Brieanne, Varbanova-Herde, Marina, DellaPenna, Dean, McKnight, Thomas D., O’Connor, Sarah, Buell, C. Robin“…One group of plant-derived compounds, the monoterpene indole alkaloids (MIAs), includes well-documented therapeutic agents used in the treatment of cancer (vinblastine, vincristine, camptothecin), hypertension (reserpine, ajmalicine), malaria (quinine), and as analgesics (7-hydroxymitragynine). …”
Publicado 2012
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27347“…This analysis provides key insights into the barriers of bed net ownership, which will help inform both LF and malaria bed net distribution campaigns as part of an integrated vector management strategy.…”
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27348“…The larger extent of genetic polymorphism identified from limited samples advocates to screen genetic polymorphism in pvrbp-2 from malaria endemic geographical regions and countries for designing pvrbp-2 based anti-malarial control measures.…”
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27349por Pell, Christopher, Meñaca, Arantza, Were, Florence, Afrah, Nana A., Chatio, Samuel, Manda-Taylor, Lucinda, Hamel, Mary J., Hodgson, Abraham, Tagbor, Harry, Kalilani, Linda, Ouma, Peter, Pool, Robert“…METHODS: Data were collected as part of a programme of qualitative research investigating the social and cultural context of malaria in pregnancy. A range of methods was employed interviews, focus groups with diverse respondents and observations in local communities and health facilities. …”
Publicado 2013
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27350por Roetynck, Sophie, Olotu, Ally, Simam, Joan, Marsh, Kevin, Stockinger, Brigitta, Urban, Britta, Langhorne, Jean“…Finally, endemic exposure to malaria in rural Kenya may have influenced the expansion of few discrete CD4 T cell populations with specific functional signatures. …”
Publicado 2013
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27351por Torres-Sánchez, Luisa, Schnaas, Lourdes, Rothenberg, Stephen J., Cebrián, Mariano E., Osorio-Valencia, Erika, Hernández, María del Carmen, García-Hernández, Rosa María, López-Carrillo, Lizbeth“…Conclusions: These findings support the hypothesis that prenatal DDE impairs early child neurodevelopment; the potential for adverse effects on development should be considered when using DDT for malaria control.…”
Publicado 2012
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27352por Timoshevskiy, Vladimir A., Severson, David W., deBruyn, Becky S., Black, William C., Sharakhov, Igor V., Sharakhova, Maria V.“…As a result, QTLs related to the transmission of the filarioid nematode Brugia malayi, the avian malaria parasite Plasmodium gallinaceum, and the dengue virus, as well as sex determination locus and 183 Mbp of genomic sequences were anchored to the exact positions on Ae. aegypti chromosomes. …”
Publicado 2013
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27353por Luckhart, Shirley, Giulivi, Cecilia, Drexler, Anna L., Antonova-Koch, Yevgeniya, Sakaguchi, Danielle, Napoli, Eleonora, Wong, Sarah, Price, Mark S., Eigenheer, Richard, Phinney, Brett S., Pakpour, Nazzy, Pietri, Jose E., Cheung, Kong, Georgis, Martha, Riehle, Michael“…The overexpression of activated, myristoylated Akt in the midgut of female transgenic Anopheles stephensi results in resistance to infection with the human malaria parasite Plasmodium falciparum but also decreased lifespan. …”
Publicado 2013
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27354por Müller, Pie, Pflüger, Valentin, Wittwer, Matthias, Ziegler, Dominik, Chandre, Fabrice, Simard, Frédéric, Lengeler, Christian“…Vector control is the mainstay of malaria control programmes. Successful vector control profoundly relies on accurate information on the target mosquito populations in order to choose the most appropriate intervention for a given mosquito species and to monitor its impact. …”
Publicado 2013
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27355por Baton, Luke Anthony, Pacidônio, Etiene Casagrande, Gonçalves, Daniela da Silva, Moreira, Luciano Andrade“…However, wFlu does not inhibit, and even enhances, oocyst infection with the avian malaria parasite Plasmodium gallinaceum. The stage- and sex-specific density of wFlu was relatively low, and with limited tissue distribution, consistent with the lack of virulence and pathogen interference/symbiont-mediated protection observed. …”
Publicado 2013
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27356por da Silva, Gloria NS, Maria, Nicole RG, Schuck, Desirée C, Cruz, Laura N, de Moraes, Miriam S, Nakabashi, Myna, Graebin, Cedric, Gosmann, Grace, Garcia, Célia RS, Gnoatto, Simone CB“…BACKGROUND: The discovery and development of anti-malarial compounds of plant origin and semisynthetic derivatives thereof, such as quinine (QN) and chloroquine (CQ), has highlighted the importance of these compounds in the treatment of malaria. Ursolic acid analogues bearing an acetyl group at C-3 have demonstrated significant anti-malarial activity. …”
Publicado 2013
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27357por Sana, Theodore R., Gordon, D. Benjamin, Fischer, Steven M., Tichy, Shane E., Kitagawa, Norton, Lai, Cindy, Gosnell, William L., Chang, Sandra P.“…Malaria is a global infectious disease that threatens the lives of millions of people. …”
Publicado 2013
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27358por Takeshita, Louise Y. C., Gonzalez-Galarza, Faviel F., dos Santos, Eduardo J. M., Maia, Maria Helena T., Rahman, Mushome M., Zain, Syed M. S., Middleton, Derek, Jones, Andrew R.“…Here, we report the creation of a new database within AFND, named KIR and Diseases Database (KDDB), capturing a large quantity of data derived from publications in which KIR genes, alleles, genotypes and/or haplotypes have been associated with infectious diseases (e.g. hepatitis C, HIV, malaria), autoimmune disorders (e.g. type I diabetes, rheumatoid arthritis), cancer and pregnancy-related complications. …”
Publicado 2013
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27359por Reiner, Robert C., Perkins, T. Alex, Barker, Christopher M., Niu, Tianchan, Chaves, Luis Fernando, Ellis, Alicia M., George, Dylan B., Le Menach, Arnaud, Pulliam, Juliet R. C., Bisanzio, Donal, Buckee, Caroline, Chiyaka, Christinah, Cummings, Derek A. T., Garcia, Andres J., Gatton, Michelle L., Gething, Peter W., Hartley, David M., Johnston, Geoffrey, Klein, Eili Y., Michael, Edwin, Lindsay, Steven W., Lloyd, Alun L., Pigott, David M., Reisen, William K., Ruktanonchai, Nick, Singh, Brajendra K., Tatem, Andrew J., Kitron, Uriel, Hay, Simon I., Scott, Thomas W., Smith, David L.“…Mathematical models of mosquito-borne pathogen transmission originated in the early twentieth century to provide insights into how to most effectively combat malaria. The foundations of the Ross–Macdonald theory were established by 1970. …”
Publicado 2013
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27360por Bourke, Brian Patrick, Oliveira, Tatiane Porangaba, Suesdek, Lincoln, Bergo, Eduardo Sterlino, Sallum, Maria Anice Mureb“…Here we evaluate a multi-locus system for the identification of potential malaria vectors in the Anopheles strodei subgroup. …”
Publicado 2013
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