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27481por Prodger, Jessica L., Ssemaganda, Aloysious, Ssetaala, Ali, Kitandwe, Paul K., Muyanja, Enoch, Mpendo, Juliet, Nanvubya, Annet, Wambuzi, Mathias, Nielsen, Leslie, Kiwanuka, Noah, Kaul, Rupert“…METHODOLOGY/PRINCIPAL FINDINGS: Foreskin tissue and blood were obtained from 34 HIV- and malaria-uninfected Ugandan men who volunteered for elective circumcision, 12 of whom were definitively positive for S. mansoni eggs in stool and 12 definitively negative for both S. mansoni eggs and worm antigen. …”
Publicado 2015
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27482por Tebeu, Pierre-Marie, Halle-Ekane, Gregory, Da Itambi, Maxwell, Mbu, Robinson Enow, Mawamba, Yvette, Fomulu, Joseph Nelson“…Causes of deaths were: postpartum hemorrhage (229.2%), unsafe abortion (25%), ectopic pregnancy (12.5%), hypertension in pregnancy (8.3%), malaria (8.3%), anemia (8.3%), heart disease (4.2%), and pneumonia (4.2%), and placenta praevia (4.2%). …”
Publicado 2015
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27483“…Antenatal care, tetanus immunization in pregnancy, prophylactic antimalarials during pregnancy, induction of labour for prolonged pregnancy, case management of neonatal sepsis, meningitis and pneumonia, prophylactic and therapeutic use of surfactant, continuous positive airway pressure for neonatal resuscitation, case management of childhood malaria and pneumonia, vitamin A as part of treatment for measles associated pneumonia for children above 6 months, and home visits across the continuum of care, were identified as promising interventions for reducing neonatal, infant, child or perinatal mortality. …”
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27484por Han, Jin-Hee, Li, Jian, Wang, Bo, Lee, Seong-Kyun, Nyunt, Myat Htut, Na, Sunghun, Park, Jeong-Hyun, Han, Eun-Taek“…The expressed proteins were used to evaluate the humoral immune response with vivax malaria patients and healthy individual serum samples by protein microarray. …”
Publicado 2015
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27485por Guenot, Marianne, Loizon, Séverine, Howard, Jennifer, Costa, Giulia, Baker, David A., Mohabeer, Shaneel Y., Troye-Blomberg, Marita, Moreau, Jean-François, Déchanet-Merville, Julie, Mercereau-Puijalon, Odile, Mamani-Matsuda, Maria, Behr, Charlotte“…Malaria induces potent activation and expansion of the Vγ9Vδ2 subpopulation of γδT cells, which inhibit the Plasmodium falciparum blood cycle through soluble cytotoxic mediators, abrogating merozoite invasion capacity. …”
Publicado 2015
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27486por Wang, Qi, Rosa, Bruce A., Nare, Bakela, Powell, Kerrie, Valente, Sergio, Rotili, Dante, Mai, Antonello, Marshall, Garland R., Mitreva, Makedonka“…In this work, we identify the KDAC protein families in representative species across important classes of parasites, screen a compound library of 23 hydroxamate- or benzamide-based small molecules KDAC inhibitors, and report their activities against a range of parasitic species, including the pathogen of malaria (Plasmodium falciparum), kinetoplastids (Trypanosoma brucei and Leishmania donovani), and nematodes (Brugia malayi, Dirofilaria immitis and Haemonchus contortus). …”
Publicado 2015
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27487por Sothmann, Peter, Krumkamp, Ralf, Kreuels, Benno, Sarpong, Nimako, Frank, Clemens, Ehlkes, Lutz, Fobil, Julius, Gyau, Kennedy, Jaeger, Anna, Bosu, Benedicta, Marks, Florian, Owusu-Dabo, Ellis, Salzberger, Bernd, May, Jürgen“…Blood was taken for bacterial culture and malaria diagnostics. The socio-economic status of participants was calculated using Principle Component Analysis. …”
Publicado 2015
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27488por Muthumbi, Esther, Morpeth, Susan C., Ooko, Michael, Mwanzu, Alfred, Mwarumba, Salim, Mturi, Neema, Etyang, Anthony O., Berkley, James A., Williams, Thomas N., Kariuki, Samuel, Scott, J. Anthony G.“…Risk factors for invasive NTS disease were human immunodeficiency virus infection, malaria, and malnutrition; the case fatality ratio was 22.1% (71/321) in children aged <5 years and 36.7% (11/30) in adults. …”
Publicado 2015
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27489“…We start with a country-based (bottom-up) analysis of the costs and impact of scaling up reproductive, maternal, and child health tools, and select HIV and malaria interventions. We then incorporate global (top-down) analyses of the costs and impacts of scaling up existing tools for tuberculosis, additional HIV interventions, the costs to strengthen health systems, and the costs and benefits from scaling up new health interventions over the time horizon of this forecast. …”
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27490por Rattanapunya, Siwalee, Cressey, Tim R., Rueangweerayut, Ronnatrai, Tawon, Yardpiroon, Kongjam, Panida, Na-Bangchang, Kesara“…BACKGROUND: Concomitant use of anti-malarial and antiretroviral drugs is increasingly frequent in malaria and HIV endemic regions. The aim of the study was to investigate the pharmacokinetic interaction between the anti-malarial drugs, artesunate-mefloquine and the antiretroviral drug, lopinavir boosted with ritonavir (LPV/r). …”
Publicado 2015
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27491por Tokieda, Sumika, Komori, Marie, Ishiguro, Toshifumi, Iwakura, Yoichiro, Takahara, Kazuhiko, Inaba, Kayo“…It was reported that Dcir1 is required to maintain homeostasis of the immune system to prevent autoimmunity, but it is also involved in the development of infectious disease resulting in the enhanced severity of cerebral malaria. However, the role of Dcir1 in intestinal immune responses during colitis remains unclear. …”
Publicado 2015
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27492por Rodríguez, Daniela C, Shearer, Jessica, Mariano, Alda RE, Juma, Pamela A, Dalglish, Sarah L, Bennett, Sara“…Integrated Community Case Management of Childhood Illness (iCCM) is a policy for providing treatment for malaria, diarrhoea and pneumonia for children below 5 years at the community level, which is generating increasing evidence and support at the global level. …”
Publicado 2015
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27493por Kaiser, Annette, Langer, Barbara, Przyborski, Jude, Kersting, David, Krüger, Mirko“…During its development the malaria parasite P. falciparum has to adapt to various different environmental contexts. …”
Publicado 2015
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27494“…Estimates of multilateral ODA financing for HIV/AIDS were based on the country allocations announcement by the Global Fund to Fight AIDS, Tuberculosis and Malaria (the Global Fund) for the period 2014 to 2016. …”
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27495por Kemppainen, Petri, Knight, Christopher G, Sarma, Devojit K, Hlaing, Thaung, Prakash, Anil, Maung Maung, Yan Naung, Somboon, Pradya, Mahanta, Jagadish, Walton, Catherine“…We analysed such networks in two test cases: a new restriction-site-associated DNA sequence (RAD-seq) data set for Anopheles baimaii, a Southeast Asian malaria vector; and a well-characterized single nucleotide polymorphism (SNP) data set from 21 three-spined stickleback individuals. …”
Publicado 2015
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27496por Lu, Guangyu, Traoré, Corneille, Meissner, Peter, Kouyaté, Bocar, Kynast-Wolf, Gisela, Beiersmann, Claudia, Coulibaly, Boubacar, Becher, Heiko, Müller, Olaf“…BACKGROUND: Insecticide-treated bed nets (ITNs) are now the main tool for malaria prevention in endemic areas. Synthetic pyrethroids are the only group of insecticides recommended by the World Health Organization for the use on ITNs. …”
Publicado 2015
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27497por Khan, Naveed, Akhtar, Muhammad Shoaib, Khan, Barkat Ali, Braga, Valdir de Andrade, Reich, Adam“…(Family: Amaranthaceae), popularly known as Charchitta or Pitpapra, is commonly used by traditional healers for the treatment of fever, malaria, dysentery, asthma, arterial hypertension, pneumonia, and diabetes. …”
Publicado 2015
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27498por Ekins, Sean, Freundlich, Joel S., Clark, Alex M., Anantpadma, Manu, Davey, Robert A., Madrid, Peter“…Pyronaridine is a component of a combination therapy for malaria that was recently approved by the European Medicines Agency, which may make it more readily accessible for clinical testing. …”
Publicado 2017
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27499“…Swertia chirayita (Gentianaceae), a popular medicinal herb indigenous to the temperate Himalayas is used in traditional medicine to treat numerous ailments such as liver disorders, malaria, and diabetes and are reported to have a wide spectrum of pharmacological properties. …”
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27500por Yeda, Redemptah, Ingasia, Luicer A., Cheruiyot, Agnes C., Okudo, Charles, Chebon, Lorna J., Cheruiyot, Jelagat, Akala, Hoseah M., Kamau, Edwin“…Parasites collected from three different patients presenting with uncomplicated malaria were adapted and maintained in drug-free continuous cultures. …”
Publicado 2016
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