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27601por Gibson, Lauren E., Markwalter, Christine F., Kimmel, Danielle W., Mudenda, Lwiindi, Mbambara, Saidon, Thuma, Philip E., Wright, David W.“…In the field, blood samples for the study and diagnosis of malaria are often collected on dried blood spot cards, so development of a biomarker extraction and analysis method is needed. …”
Publicado 2017
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27602por Njomatchoua, Audrey Carine, Tankeu, Aurel Tiakouang, Sobngwi, Eugene, Mbanya, Jean-Claude“…This suggests the need for close monitoring in patients at risk of hypoglycemia such as those with severe malaria especially during the first hour of quinine infusion.…”
Publicado 2017
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27603por Bancone, Germana, Kalnoky, Michael, Chu, Cindy S., Chowwiwat, Nongnud, Kahn, Maria, Malleret, Benoit, Wilaisrisak, Pornpimon, Rénia, Laurent, Domingo, Gonzalo J., Nosten, Francois“…Glucose-6-phosphate dehydrogenase (G6PD) activity is essential for redox equilibrium of red blood cells (RBCs) and, when compromised, the RBCs are more susceptible to haemolysis. 8-aminoquinolines (primaquine and tafenoquine) are used for the radical curative treatment of Plasmodium vivax malaria and can cause haemolysis in G6PD deficient subjects. …”
Publicado 2017
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27604por Thomas, Adelina, Mazigo, Humphrey D., Manjurano, Alphaxard, Morona, Domenica, Kweka, Eliningaya J.“…BACKGROUND: Mosquitoes are well-known vectors of many diseases including malaria and lymphatic filariasis. Uses of synthetic insecticides are associated with high toxicity, resistance, environmental pollution and limited alternative, effective synthetic insecticides. …”
Publicado 2017
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27605por Leba, Louis-Jérôme, Popovici, Jean, Estevez, Yannick, Pelleau, Stéphane, Legrand, Eric, Musset, Lise, Duplais, Christophe“…The search for safe antimalarial compounds acting against asexual symptom-responsible stages and sexual transmission-responsible forms of Plasmodium species is one of the major challenges in malaria elimination programs. So far, among current drugs approved for human use, only primaquine has transmission-blocking activity. …”
Publicado 2017
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27606“…Artesunate is a potent and rapidly acting blood schizontocide used to treat chloroquine resistant malaria. Artesunate has been reported to cause embryo, reduced reproductive capacity, hepatotoxicity, neurotoxicity and hematological abnormalities. …”
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27607por Sudfeld, Christopher R., Manji, Karim P., Smith, Emily R., Aboud, Said, Kisenge, Rodrick, Fawzi, Wafaie W., Duggan, Christopher P.“…There was also no association of low vitamin D with the incidence of diarrhea, upper respiratory infection, acute lower respiratory tract infection, or malaria. CONCLUSIONS: Vitamin D deficiency is common during early infancy, particularly among exclusively breastfed infants; however, these observational data suggest it may not be an important contributor to morbidity and growth among the general population of Tanzanian infants. …”
Publicado 2017
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27608por Lee, Shwu-Maan, Wu, Chia-Kuei, Plieskatt, Jordan L., Miura, Kazutoyo, Hickey, John M., King, C. Richter“…Transmission-blocking vaccines have the potential to accelerate malaria parasite elimination by inducing antibodies that block parasite transmission from humans to mosquitoes. …”
Publicado 2017
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27609“…AIM: This research was conducted to evaluate the molluscicidal and mosquitocidal efficacy of silica nanoparticles in the eradication of the larvae and pupa of malaria and filariasis vector as well as vectors of rift-valley fever virus (Culex pipiens); Schistosoma mansoni vector and Biomphlaria alexandrina (snail and egg masses). …”
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27610por Ntumngia, Francis B., Pires, Camilla V., Barnes, Samantha J., George, Miriam T., Thomson-Luque, Richard, Kano, Flora S., Alves, Jessica R. S., Urusova, Darya, Pereira, Dhelio B., Tolia, Niraj H., King, Christopher L., Carvalho, Luzia H., Adams, John H.“…These successful results indicate a potential approach that can be used generally to improve efficacy of other malaria vaccine candidates.…”
Publicado 2017
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27611“…The mosquito species Anopheles plumbeus is an aggressive biter and a potential vector of malaria parasites and West Nile virus. It occurs naturally at low population densities, as its larval development is adapted to the specific water qualities found in tree holes. …”
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27612por Beshir, Khalid B., Sepúlveda, Nuno, Bharmal, Jameel, Robinson, Ailie, Mwanguzi, Julian, Busula, Annette Obukosia, de Boer, Jetske Gudrun, Sutherland, Colin, Cunningham, Jane, Hopkins, Heidi“…Deletions of the Plasmodium falciparum hrp2 and hrp3 genes can affect the performance of HRP2-based malaria rapid diagnostic tests (RDTs). Such deletions have been reported from South America, India and Eritrea. …”
Publicado 2017
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27613por Gao, Zi-Hou, Huang, Tao-Hua, Jiang, Bao-Gui, Jia, Na, Liu, Zheng-Xiang, Shao, Zong-Ti, Jiang, Rui-Ruo, Liu, Hong-Bo, Wei, Ran, Li, Yu-Qiong, Yao, Hong-Wu, von Fricken, Michael E., Jiang, Jia-Fu, Du, Chun-Hong, Cao, Wu-Chun“…BACKGROUND: Babesia, usually found in wild and domestic mammals worldwide, have recently been responsible for emerging malaria-like zoonosis in infected patients. Human B. microti infection has been identified in China, primarily in the Southwest along the Myanmar border but little direct surveillance of B. microti infection in rodents has been carried out here (Yunnan province). …”
Publicado 2017
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27614por Mbatchou, Valentine C., Tchouassi, David P., Dickson, Rita A., Annan, Kofi, Mensah, Abraham Y., Amponsah, Isaac K., Jacob, Julia W., Cheseto, Xavier, Habtemariam, Solomon, Torto, Baldwyn“…We investigated the mosquito larvicidal activity of the seed extract and its major anthraquinones against larvae of the African malaria vector Anopheles gambiae (s.s.). METHODS: Third-fourth instar larval mortality was observed after 24, 48, 72 and 96 h of exposure to varying doses of the extracts, and two anthraquinones isolates identified using liquid chromatography- quadrupole time of flight mass spectrometry (LC-QtoF-MS). …”
Publicado 2017
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27615por Saini, Ekta, Zeeshan, Mohammad, Brady, Declan, Pandey, Rajan, Kaiser, Gesine, Koreny, Ludek, Kumar, Pradeep, Thakur, Vandana, Tatiya, Shreyansh, Katris, Nicholas J., Limenitakis, Rebecca Stanway, Kaur, Inderjeet, Green, Judith L., Bottrill, Andrew R., Guttery, David S., Waller, Ross F., Heussler, Volker, Holder, Anthony A., Mohmmed, Asif, Malhotra, Pawan, Tewari, Rita“…Plasmodium parasites, the causative agents of malaria, possess a distinctive membranous structure of flattened alveolar vesicles supported by a proteinaceous network, and referred to as the inner membrane complex (IMC). …”
Publicado 2017
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27616por Nigatu, Tilahun Alemayehu, Afework, Mekbeb, Urga, Kelbessa, Ergete, Wondwossen, Makonnen, Eyasu“…BACKGROUND: In southeast Ethiopia, people locally use the roots of Gnidia stenophylla Gilg (Thymelaeaceae) to cure malaria and other diseases with no literature evidence substantiating its safety. …”
Publicado 2017
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27617por Kumar, Krishan, Srinivasan, Prakash, Nold, Michael J., Moch, J. Kathleen, Reiter, Karine, Sturdevant, Dan, Otto, Thomas D., Squires, R. Burke, Herrera, Raul, Nagarajan, Vijayaraj, Rayner, Julian C., Porcella, Stephen F., Geromanos, Scott J., Haynes, J. David, Narum, David L.“…The symptoms of malaria are brought about by blood-stage parasites, which are established when merozoites invade human erythrocytes. …”
Publicado 2017
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27618por Targueta, Eduardo Pelegrineti, Hirano, André Carramenha de Góes, de Campos, Fernando Peixoto Ferraz, Martines, João Augusto dos Santos, Lovisolo, Silvana Maria, Felipe-Silva, Aloisio“…Currently, the high frequency of S and C genes reflects natural selection through the protection of heterozygotes against severe malaria, the high frequency of consanguineous marriages, improvement of some public health policies and the nutritional standards in the poorer countries where newborns are now living long enough to present for diagnosis and management. …”
Publicado 2017
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27619por Osman, Marwa, Shigidi, Mazin, Ahmed, Haider, Abdelrahman, Ihab, Karrar, Wieam, Elhassan, Elhussein, Shwaib, Hussam, Ibrahim, Rayyan, Abdalla, Marwa“…Sepsis, volume depletion, obstructive uropathy, heart failure, acute glomerulonephritis and severe malaria were the commonest causes of AKI diagnosed in 44%, 38.5%, 8.9%, 5.7%, 4.7% and 3.1% of patients, respectively. …”
Publicado 2017
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27620por Pan, Xiaoling, Pike, Andrew, Joshi, Deepak, Bian, Guowu, McFadden, Michael J, Lu, Peng, Liang, Xiao, Zhang, Fengrui, Raikhel, Alexander S, Xi, Zhiyong“…When Wolbachia is artificially forced to form symbiosis with this new mosquito host, it boosts the basal immune response and enhances the mosquito’s resistance to pathogens, including dengue, Zika virus and malaria parasites. The mechanisms involved in establishing a symbiotic relationship between Wolbachia and A. aegypti, and the long-term outcomes of this interaction, are not well understood. …”
Publicado 2018
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