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27701por Arcà, Bruno, Colantoni, Alessio, Fiorillo, Carmine, Severini, Francesco, Benes, Vladimir, Di Luca, Marco, Calogero, Raffaele A., Lombardo, Fabrizio“…To get insights into saliva and salivary gland miRNA repertoires of the African malaria vector Anopheles coluzzii we used small RNA-Seq and identified 214 miRNAs, including tissue-enriched, sex-biased and putative novel anopheline miRNAs. …”
Publicado 2019
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27702Identification of antiplasmodial triterpenes from Keetia species using NMR-based metabolic profilingpor Freire, Rafael Teixeira, Bero, Joanne, Beaufay, Claire, Selegato, Denise Medeiros, Coqueiro, Aline, Choi, Young Hae, Quetin-Leclercq, Joëlle“…INTRODUCTION: The increase in multidrug resistance and lack of efficacy in malaria therapy has propelled the urgent discovery of new antiplasmodial drugs, reviving the screening of secondary metabolites from traditional medicine. …”
Publicado 2019
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27703Behavior and abundance of Anopheles darlingi in communities living in the Colombian Amazon riversidepor Prado, César Camilo, Alvarado-Cabrera, Luis Antonio, Camargo-Ayala, Paola Andrea, Garzón-Ospina, Diego, Camargo, Milena, Soto-De León, Sara Cecilia, Cubides, Juan Ricardo, Celis-Giraldo, Carmen Teresa, Patarroyo, Manuel Elkin, Patarroyo, Manuel Alfonso“…In the past few years, relative frequencies of malaria parasite species in communities living in the Colombian Amazon riverside have changed, being Plasmodium vivax (61.4%) and Plasmodium malariae (43.8%) the most frequent. …”
Publicado 2019
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27704por Tewabe, Yitagesu, Kefarge, Belete, Belay, Habtamu, Bisrat, Daniel, Hailu, Asrat, Asres, Kaleab“…Local people in the Somalia region of Ethiopia use the leaves of Aloe macrocarpa Todaro for the treatment of malaria, jaundice, and skin diseases. In our ongoing search for new, efficient, and safe antileishmanial drugs, we investigated the leaf latex of Aloe macrocarpa and its acid-hydrolyzed product aloin A/B (1), as well as the semisynthesized derivatives of aloin A/B, namely, aloe-emodin (2) and rhein (3) against promastigotes and axenically cultured amastigotes of Leishmania aethiopica and L. donovani clinical isolates. …”
Publicado 2019
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27705por Mwangi, Martin N., Echoka, Elizabeth, Knijff, Marthe, Kaduka, Lydia, Werema, Brenda G., Kinya, Frida M., Mutisya, Richard, Muniu, Erastus M., Demir, Ayşe Y., Verhoef, Hans, Bourdet-Sicard, Raphaelle“…We re-analyzed data from pregnant Kenyan women living in a rural area where malaria is highly endemic (n = 470) or in an urban area (n = 402). …”
Publicado 2019
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27706por Mota, Caroline Martins, Santiago, Fernanda Maria, Cardoso, Mariana de Resende Damas, Rostkowska, Cristina, de Oliveira, Taísa Carrijo, Silva, Deise Aparecida de Oliveira, Pirovani, Carlos Priminho, Mineo, Tiago Wilson Patriarca, Mineo, José Roberto“…Bidens pilosa Linné has been used in ethnopharmacology for treatment of diseases, as malaria, diabetes and hepatitis, in addition to its use as antioxidant, antiallergic, anti-inflammatory, and antiviral. …”
Publicado 2019
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27707por Andersson, Anne-Marie C., Buldun, Can M., Pattinson, David J., Draper, Simon J., Howarth, Mark“…SnoopLigase-mediated nanoassembly enhanced the antibody response to both malaria antigens in a prime-boost model. Including or depleting SnoopLigase from the conjugate had little effect on the antibody response to the malarial antigens. …”
Publicado 2019
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27708por Musimwa, Aimée Mudekereza, Kitoko, Hermann Tamubango, Wakamb, Gray Kanteng, Okitotsho, Stanis Wembonyama, Numbi, Oscar Luboya“…CONCLUSION: serum iron concentration were lower in acutely or chronically malnourished children on admission, with a mean iron concentration of approximately 159.5 μg/L; this would justify the vast iron fortification programs of different foods and/or the administration of iron in the first week while treating complications (malaria, bacterial infections and other parasitic infections).…”
Publicado 2018
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27709por Prodjosoewojo, Susantina, Riswari, Silvita F., Djauhari, Hofiya, Kosasih, Herman, van Pelt, L. Joost, Alisjahbana, Bachti, van der Ven, Andre J., de Mast, Quirijn“…A definite infectious etiology could be determined in 190 of 463 evaluable patients (41%), including 89 arboviral infections (81 dengue and 8 chikungunya), 94 bacterial infections (26 murine typhus, 16 salmonellosis, 6 leptospirosis and 46 cosmopolitan bacterial infections), 3 concomitant arboviral-bacterial infections, and 4 malaria infections. The IMS detected inflammation in all but two participants. …”
Publicado 2019
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27710por Bernardini, Federica, Kriezis, Antonios, Galizi, Roberto, Nolan, Tony, Crisanti, Andrea“…These distorter male mosquitoes can efficiently suppress caged wild-type populations, providing a powerful tool for vector control strategies. Given that malaria mosquito vectors belong to a species complex comprising at least two major vectors, we investigated whether the sex distorter I-PpoI, originally integrated in the A. gambiae genome, could be transferred via introgression to the sibling vector species Anopheles arabiensis. …”
Publicado 2019
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27711por Collins, Katharine A., Rückle, Thomas, Elliott, Suzanne, Marquart, Louise, Ballard, Emma, Chalon, Stephan, Griffin, Paul, Möhrle, Jörg J., McCarthy, James S.“…In a previous phase 1b study, a single 150-mg dose of DSM265 showed partial efficacy against experimentally induced blood-stage Plasmodium falciparum malaria (IBSM). Pharmacokinetic/pharmacodynamic modeling predicted a human efficacious dose of 340 mg. …”
Publicado 2019
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27712“…Twenty samples collected from patients with dengue, typhoid, and malaria tested by the LAMP assay were negative, indicating its good specificity. …”
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27713por Kebede, Alebachew Messele, Tadesse, Fitsum Girma, Feleke, Adey Desta, Golassa, Lemu, Gadisa, Endalamaw“…The phenomenon of phenotypic plasticity and implication of LCRs in malaria immunology in general and vaccine candidate genes in particular merits further exploration. …”
Publicado 2019
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27714por Bernier, Ulrich R., Kline, Daniel L., Vazquez-Abad, Agustin, Perry, Melynda, Cohnstaedt, Lee W., Gurman, Pablo, D’hers, Sebastián, Elman, Noel M.“…The presented work therefore presents a new methodology for improving design, development and deployment of vector-control tools to reduce transmission of vector-borne diseases, including malaria and dengue.…”
Publicado 2019
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27715por Juma, Dennis W., Muiruri, Peninah, Yuhas, Krista, John-Stewart, Grace, Ottichilo, Ronald, Waitumbi, John, Singa, Benson, Polyak, Christina, Kamau, Edwin“…OBJECTIVE: Cotrimoxazole prevents opportunistic infections including falciparum malaria in HIV-infected individuals but there are concerns of cross-resistance to other antifolate drugs such as sulphadoxine-pyrimethamine (SP). …”
Publicado 2019
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27716por Le-Viet, Nhiem, Le, Viet-Nho, Chung, Hai, Phan, Duc-Tuan, Phan, Quang-Duong, Cao, Thanh-Van, Abat, Cédric, Raoult, Didier, Parola, Philippe“…A total of 378 febrile adult patients (AUFs) with a fever for ≤21 days, no evidence of localized infection and negative screening tests for dengue and malaria, and 384 afebrile adult patients (Controls) were prospectively enrolled. …”
Publicado 2019
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27717“…BACKGROUND: The recent finding of a typically non-African Anopheles species in eastern Ethiopia emphasizes the need for detailed species identification and characterization for effective malaria vector surveillance. Molecular approaches increase the accuracy and interoperability of vector surveillance data. …”
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27718por Marenga, Giuseppe, Traficante, Silvia, Ragonici, Serena, Vincenzi, Claudia, Rocchetti, Maura, De Rito, Giuseppe, Fonsi, Giovanni Battista, Messineo, Daniela“…Patient: Male, 59 Final Diagnosis: Amoebic liver abscess Symptoms: Acute abdomen • dispnoea Medication: — Clinical Procedure: Percutaneous CT guided drainage Specialty: Surgery OBJECTIVE: Rare disease BACKGROUND: E. histolytica liver abscess results from extra-intestinal diffusion of amebiasis, which is responsible for up 100 000 deaths per annum, placing it second only to malaria in mortality. Currently, the criterion standard for the diagnosis of liver abscesses is ultrasound, but CEUS (contrast-enhanced ultrasound) is emerging as a more accurate method for liver study, and it could be more accurate than ultrasound and non-invasive compared to CT. …”
Publicado 2019
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27719por Lompo, Djingri Labodi, Diallo, Ousséini, Dao, Ben Aziz, Bassole, Romaric, Napon, Christian, Kabore, Jean“…CONCLUSION: The improvement of policies in the field of maternal and child health and the generalization of the control of infectious and parasitic diseases, including malaria, may contribute to the reduction of non-genetic epilepsy in sub-Saharan Africa.…”
Publicado 2018
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27720por Skinner-Adams, Tina S., Fisher, Gillian M., Riches, Andrew G., Hutt, Oliver E., Jarvis, Karen E., Wilson, Tony, von Itzstein, Mark, Chopra, Pradeep, Antonova-Koch, Yevgeniya, Meister, Stephan, Winzeler, Elizabeth A., Clarke, Mary, Fidock, David A., Burrows, Jeremy N., Ryan, John H., Andrews, Katherine T.“…Atovaquone-proguanil (Malarone®) is used for malaria prophylaxis and treatment. While the cytochrome bc1-inhibitor atovaquone has potent activity, proguanil’s action is attributed to its cyclization-metabolite, cycloguanil. …”
Publicado 2019
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