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27761por Mitran, Catherine J., Mena, Angie, Gnidehou, Sedami, Banman, Shanna, Arango, Eliana, Lima, Barbara A. S., Lugo, Hazel, Ganesan, Aravindhan, Salanti, Ali, Mbonye, Anthony K., Ntumngia, Francis, Barakat, Khaled, Adams, John H., Kano, Flora S., Carvalho, Luzia H., Maestre, Amanda E., Good, Michael F., Yanow, Stephanie K.“…We previously discovered that antibodies to the Plasmodium vivax invasion protein, PvDBP, cross-react with P. falciparum VAR2CSA, a distantly related virulence factor that mediates placental malaria. Here, we describe the molecular mechanism underlying this cross-species immunity. …”
Publicado 2019
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27762por Larson, Elysia, Mbaruku, Godfrey, Kujawski, Stephanie A, Mashasi, Irene, Kruk, Margaret E“…The most common reasons for seeking care were fever or malaria (33.9%), vaccination (33.6%) and non-emergent check-up (13.4%). …”
Publicado 2019
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27763por Nong, Xiaolin, Rajbanshi, Girju, Chen, Ling, Li, Jiaquan, Li, Zhan, Liu, Taotao, Chen, Shihai, Wei, Gao, Li, Jushang“…Although several studies reported the efficiency of artesunate in the treatment of malaria, inhibiting fibroblasts and collagen synthesis, the association between artesunate and scar formation is unclear. …”
Publicado 2019
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27764“…Data on haemoglobin level, helminths and malaria infection status at first antenatal care registration were extracted from antenatal records booklets of each pregnant women. …”
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27765“…Malaria caused by Plasmodium affects millions people worldwide. …”
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27766por del Campo, Javier, Heger, Thierry J., Rodríguez-Martínez, Raquel, Worden, Alexandra Z., Richards, Thomas A., Massana, Ramon, Keeling, Patrick J.“…Apicomplexans are a group of microbial eukaryotes that contain some of the most well-studied parasites, including the causing agents of toxoplasmosis and malaria, and emergent diseases like cryptosporidiosis or babesiosis. …”
Publicado 2019
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27767“…HIV fourth generation kits, HbsAg, HCV third generation kits, malaria and syphilis, parbovirus IgM and parbovirus IgG kits, HEV Antigen and IgM antibody were used. …”
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27768por Hamerly, Timothy, Tweedell, Rebecca E., Hritzo, Bernadette, Nyasembe, Vincent O., Tekwani, Babu L., Nanayakkara, N. P. Dhammika, Walker, Larry A., Dinglasan, Rhoel R.“…Malaria is a major global health threat, with nearly half the world’s population at risk of infection. …”
Publicado 2019
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27769por Gautam, Narayan, Gaire, Bhagwati, Manandhar, Trishna, Marasini, Bishnu P., Parajuli, Niranjan, Lekhak, Sunil P., Nepal, Monica“…Though hemoglobinopathy sometime could be protective in malaria but G6PD deficiency can cause massive hemolysis which may exacerbate the condition.…”
Publicado 2019
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27770por Huang, Xiao-Ting, Liu, Wei, Zhou, Yong, Hao, Cai-Xia, Zhou, Yan, Zhang, Chen-Yu, Sun, Chen-Chen, Luo, Zi-Qiang, Tang, Si-Yuan“…Artemisinin is used for the treatment of fever and malaria in clinical practice. Dihydroartemisinin (DHA), the major active metabolite of artemisinin, plays a role in anti-organizational fibrosis and anti-neuronal cell death. …”
Publicado 2019
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27771por Shen, Qian, Huang, Huayi, Zhao, Yu, Xie, Lihui, He, Qian, Zhong, Yijun, Wang, Yuting, Wang, Yuliang, Tang, Kexuan“…Artemisinin-based therapies are the only effective treatment for malaria, which reached to 219 million cases and killed 435,000 people in 2017. …”
Publicado 2019
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27772por Koehne, Erik, Kreidenweiss, Andrea, Zoleko Manego, Rella, McCall, Matthew, Mombo-Ngoma, Ghyslain, Mackwitz, Marcel Karl Walter, Hansen, Finn K., Held, Jana“…Parasites representing different genetic backgrounds were isolated from adults and children with uncomplicated malaria in Gabon. Clinical studies on (non-HDAC-inhibitors) antimalarials, moreover, found lower drug efficacy in children, mainly attributed to acquired immunity with age in endemic areas. …”
Publicado 2019
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27773“…BACKGROUND: The ecology of many mosquitoes, including Anopheles farauti, the dominant malaria vector in the southwest Pacific including the Solomon Islands, remains inadequately understood. …”
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27774por Lima, Marilia N. N., Cassiano, Gustavo C., Tomaz, Kaira C. P., Silva, Arthur C., Sousa, Bruna K. P., Ferreira, Leticia T., Tavella, Tatyana A., Calit, Juliana, Bargieri, Daniel Y., Neves, Bruno J., Costa, Fabio T. M., Andrade, Carolina Horta“…Malaria is a tropical infectious disease that affects over 219 million people worldwide. …”
Publicado 2019
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27775“…Clinical trials monitoring malaria drug resistance require genotyping of recurrent Plasmodium falciparum parasites to distinguish between treatment failure and new infection occurring during the trial follow up period. …”
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27776por Scheu, Katrin, Adegnika, Ayola Akim, Addo, Marylyn M., Ansong, Daniel, Cramer, Jakob P., Fürst, Svenja, Kremsner, Peter G., Kurth, Florian, Jacobs, Thomas, May, Jürgen, Ramharter, Michael, Sylverken, Justice, Vinnemeier, Christof D., Agbenyega, Tsiri, Rolling, Thierry“…We assessed mechanistic and risk factors for post-malarial anemia in Ghanaian and Gabonese children with severe P. falciparum malaria treated with parenteral artesunate followed by an oral artemisinin-combination therapy. …”
Publicado 2019
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27777por Musimbi, Zaneta D., Rono, Martin K., Otieno, James R., Kibinge, Nelson, Ochola-Oyier, Lynette Isabella, de Villiers, Etienne Pierre, Nduati, Eunice W.“…Functional enrichment analysis on both DEGs and the six significantly associated modules revealed an enrichment of G-protein coupled receptors and the immune system, specifically affecting neutrophil function and antibacterial responses. Additionally, malaria pathogenicity genes (thrombospondin 1-(THBS 1), interleukin 6 (IL6), and arginine decarboxylase 2 (ADC2)) were down-regulated. …”
Publicado 2019
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27778por Clarke-Deelder, Emma, Shapira, Gil, Samaha, Hadia, Fritsche, György Bèla, Fink, Günther“…Based on a detailed list of disease symptoms observed, patients with severe febrile disease (including malaria), severe pneumonia, and severe dehydration were identified. …”
Publicado 2019
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27779por Graham, Hamish, Bakare, Ayobami A., Ayede, Adejumoke I., Oyewole, Oladapo B., Gray, Amy, Peel, David, McPake, Barbara, Neal, Eleanor, Qazi, Shamim A., Izadnegahdar, Rasa, Duke, Trevor, Falade, Adegoke G.“…Hypoxaemia was common among children with acute lower respiratory infection (28.0%), asthma (20.4%), meningitis/encephalitis (17.4%), malnutrition (16.3%), acute febrile encephalopathy (15.4%), sepsis (8.7%) and malaria (8.5%), and neonates with neonatal encephalopathy (33.4%), prematurity (26.6%), and sepsis (21.0%). …”
Publicado 2019
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27780por Ekasari, Wiwied, Widya Pratiwi, Dwi, Amanda, Zelmira, Suciati, Widyawaruyanti, Aty, Arwati, Heny“…BACKGROUND: Each part of H. annuus plants is traditionally used as medicinal remedies for several diseases, including malaria. Antimalarial activity of the leaf and the seed has already been observed; however, there is no report about antimalarial activity of the other parts of H. annuus plants. …”
Publicado 2019
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