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  1. 27901
    “…Our results show significant IgG isotype subclass (IgG1and IgG3) response of specific antibody levels as well as cell-mediated immunity (CMI) activating factor (IFN-γ), a crucial player in conferring resistance to blood-stage malaria in mice receiving EL-PfMSP-Fu(24) through transdermal route as compared to the intramuscularly administered formulation. …”
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    Transdermal Immunization of Elastic Liposome-Laden Recombinant Chimeric Fusion Protein of P. falciparum (PfMSP-Fu(24)) Mounts Protective Immune Response
  2. 27902
    “…SIMPLE SUMMARY: Mosquitoes from the family Culicidae are vectors of numerous human diseases such as dengue, Zika, and West Nile fevers, malaria, and lymphatic filariasis. The availability of high-quality genome assemblies for mosquitoes assists in identifying genes responsible for important epidemiological traits such as vector competence, insecticide resistance, and mosquito behavior and stimulates a better understanding of the genetic structure of mosquito populations. …”
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    A Gene-Based Method for Cytogenetic Mapping of Repeat-Rich Mosquito Genomes
  3. 27903
    “…Mosquitoes vector many pathogens that cause human disease, such as malaria that is caused by parasites in the genus Plasmodium. …”
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    Novel Asaia bogorensis Signal Sequences for Plasmodium Inhibition in Anopheles stephensi
  4. 27904
    “…Monitoring of Plasmodium falciparum sensitivity to antimalarial drugs in Africa is vital for malaria elimination. However, the commonly used ex vivo/in vitro 50% inhibitory concentration (IC(50)) test gives inconsistent results for several antimalarials, while the alternative ring-stage survival assay (RSA) for artemisinin derivatives has not been widely adopted. …”
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    Tolerance of Gambian Plasmodium falciparum to Dihydroartemisinin and Lumefantrine Detected by Ex Vivo Parasite Survival Rate Assay
  5. 27905
    “…Plasmodium vivax is a world-threatening human malaria parasite, whose biology remains elusive. The unavailability of in vitro culture, and the difficulties in getting a high number of pure parasites makes RNA isolation in quantity and quality a challenge. …”
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    A suitable RNA preparation methodology for whole transcriptome shotgun sequencing harvested from Plasmodium vivax-infected patients
  6. 27906
    “…Universal “coverage” with long-lasting insecticidal nets (LLINs) is recommended for malaria control in endemic areas, but ownership does not ensure usage. …”
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    Insufficient Ratio of Long-Lasting Insecticidal Nets to Household Members Limited Universal Usage in Western Kenya: A 2015 Cross-Sectional Study
  7. 27907
    “…METHODS: Changes in the global immune profile were evaluated in three different groups of rhesus macaques previously enrolled in dengue or malaria vaccine studies over six months after their last exposure. …”
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    Exposure-related, global alterations in innate and adaptive immunity; a consideration for re-use of non-human primates in research
  8. 27908
    “…Annona muricata, a tropical plant which has been extensively used in ethnomedicine to treat a wide range of diseases, from malaria to cancer. Interestingly, this plant has been reported to demonstrate significant antiviral properties against the human immunodeficiency virus, herpes simplex virus, human papilloma virus, hepatitis C virus and dengue virus. …”
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    Evaluation of Annona muricata Acetogenins as Potential Anti-SARS-CoV-2 Agents Through Computational Approaches
  9. 27909
    “…This parametrization methodology allows direct comparison of Ig isotypes produced against various Plasmodium antigens following malaria infection, and the same methodology could be applied to other longitudinal serologic studies from P. falciparum or different pathogens. …”
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    Framework for Characterizing Longitudinal Antibody Response in Children After Plasmodium falciparum Infection
  10. 27910
    “…The leading causes of disease for children under-5 remain preterm birth and infectious diseases, pneumonia, diarrhoea and malaria. For older children and adolescents, injuries become important causes of death as do interpersonal violence and self-harm. …”
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    Patterns and trends in causes of child and adolescent mortality 2000–2016: setting the scene for child health redesign
  11. 27911
    “…API also hinders the control and prevention of malaria as infected hosts serve as silent reservoirs for transmission of Plasmodium species in the community. …”
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    Asymptomatic Plasmodium infection and associated factors among pregnant women in the Merti district, Oromia, Ethiopia
  12. 27912
    “…Of these species, 30 contain confirmed antiCOVID-19 secondary metabolites, 90 are used traditionally to manage at least 3 common symptoms of COVID-19, 10 have immunostimulant activity, 52 have anti-inflamatory activity, 14 have antiviral properties and 78 species are documented as used to treat malaria. A PCA analysis showing cluster formatting among the recorded species indicates 4 groups of species and an array of possibility of using individual species or a combination of species for their complementary effects. …”
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    A review of Cameroonian medicinal plants with potentials for the management of the COVID-19 pandemic
  13. 27913
    “…To the best of our knowledge, this is the first report on the bioactive “unnatural” natural products from the crude extract of A. galanga (L.) by chemical conversion and on its activities against causal pathogens of leishmaniasis, trypanosomiasis, and malaria.…”
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    Six New Phenylpropanoid Derivatives from Chemically Converted Extract of Alpinia galanga (L.) and Their Antiparasitic Activities
  14. 27914
    “…Atovaquone is a well-tolerated drug used in the clinic mainly against malaria. Being a ubiquinone analogue, this drug inhibits co-enzyme Q10 of the electron transport chain (ETC) affecting oxidative phosphorylation and cell metabolism. …”
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    The Protozoan Inhibitor Atovaquone Affects Mitochondrial Respiration and Shows In Vitro Efficacy Against Glucocorticoid-Resistant Cells in Childhood B-Cell Acute Lymphoblastic Leukaemia
  15. 27915
    “…The analysis of the GO biological process revealed that these DEGs were mainly enriched in wound healing, in response to wounding, cell migration, cell motility, and regulation of cell motility, while the KEGG pathway analysis found that these DEGs were mainly enriched in proteoglycans in cancer, bladder cancer, malaria, tyrosine kinase inhibitor resistance in Epidermal Growth Factor Receptor (EGFR), and the ERBB signaling pathway. …”
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    Prognostic Implication of the Expression Level of PECAM-1 in Non-small Cell Lung Cancer
  16. 27916
    “…[Image: see text] In malaria, chemical genetics is a powerful method for assigning function to uncharacterized genes. …”
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    PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum
  17. 27917
    “…Many regional health-care systems faced at least one wave of overwhelming COVID-19 case surges, and still face the possibility of a new wave of infections on the horizon, potentially in combination with other endemic diseases such as influenza, dengue, tuberculosis, and malaria. In this context, the need for an effective and scientifically informed leadership to sustain and improve global capacity to ensure international health security is starkly apparent. …”
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    COVID-19 Blind Spots: A Consensus Statement on the Importance of Competent Political Leadership and the Need for Public Health Cognizance
  18. 27918
    “…Mortality attributable to this disease exceeds that from HIV, tuberculosis and malaria combined in this region. CONTEXT: CHB is a major health problem in the Pacific island nation of Kiribati. …”
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    A programme to treat chronic hepatitis B in Kiribati: progress and challenges
  19. 27919
    “…Most factors in Western and South-East Kenya recorded moderate intervention coverage although having a high infection prevalence of both HIV and malaria. CONCLUSION: The heterogeneous estimates necessitates prioritisation of the marginalised counties to achieve health equity and improve child survival uniformly across the country. …”
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    Subnational estimates of factors associated with under-five mortality in Kenya: a spatio-temporal analysis, 1993–2014
  20. 27920
    “…Because PvAMA-1 is noticeable as vaccine candidate antigen, these documents provide valuable information for the development of malaria vaccine.…”
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    Sequence Analysis of Pvama-1 among Plasmodium Vivax Isolates in Sistan-Baluchistan
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