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28021por Perera, Dilhan J., Hassan, Adam S., Liu, Sunny S., Elahi, Seyyed Mehdy, Gadoury, Christine, Weeratna, Risini D., Gilbert, Rénald, Ndao, Momar“…According to the CDC, the impact of this disease is second to only malaria as the most devastating parasitic infection. …”
Publicado 2022
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28022por Mohebi, Marjan, Fayazi, Neda, Esmaeili, Somayeh, Rostami, Mahboubeh, Bagheri, Fereshteh, Aliabadi, Alireza, Asadi, Parvin, Saghaie, Lotfollah“…BACKGROUND AND PURPOSE: Malaria and cancer are two major health issues affecting millions of lives annually. …”
Publicado 2022
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28023por Liu, Qin, Zhan, Xueyan, Li, Dongfang, Zhao, Junlong, Wei, Haiyong, Alzan, Heba, He, Lan“…ABSTRACT: Babesia gibsoni is a malaria-like protozoan that parasitizes the red blood cells of canids to cause babesiosis. …”
Publicado 2022
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28024por Wansri, Rattanaporn, Lin, Aye Chan Khine, Pengon, Jutharat, Kamchonwongpaisan, Sumalee, Srimongkolpithak, Nitipol, Rattanajak, Roonglawan, Wilasluck, Patcharin, Deetanya, Peerapon, Wangkanont, Kittikhun, Hengphasatporn, Kowit, Shigeta, Yasuteru, Liangsakul, Jatupol, Suroengrit, Aphinya, Boonyasuppayakorn, Siwaporn, Chuanasa, Taksina, De-eknamkul, Wanchai, Hannongbua, Supot, Rungrotmongkol, Thanyada, Chamni, Supakarn“…Therefore, new aryl amide analogs of piperine 5 should be investigated further as a promising anti-infective agent against human African trypanosomiasis, malaria, and COVID-19.…”
Publicado 2022
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28025por Acosta-Pérez, Tomás, Rodríguez-Yánez, Tomás, Almanza-Hurtado, Amilkar, Martínez-Ávila, María Cristina, Dueñas-Castell, Carmelo“…An area of epidemiological relevance is Latin America, tropical regions, due to the distribution of endemic diseases such as chikungunya, dengue (DENV), malaria, Zika virus, where febrile disease abounds. …”
Publicado 2022
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28026por Khandelwal, Akash, Arez, Francisca, Alves, Paula M., Badolo, Lassina, Brito, Catarina, Fischli, Christoph, Fontinha, Diana, Oeuvray, Claude, Prudêncio, Miguel, Rottmann, Matthias, Wilkins, Justin, Yalkinoglu, Özkan, Bagchus, Wilhelmina M., Spangenberg, Thomas“…BACKGROUND: Targeting the asymptomatic liver stage of Plasmodium infection through chemoprevention could become a key intervention to reduce malaria-associated incidence and mortality. METHODS: M5717, a Plasmodium elongation factor 2 inhibitor, was assessed in vitro and in vivo with readily accessible Plasmodium berghei parasites. …”
Publicado 2022
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28027por Ali, Ali Mohamed, Gausi, Kamunkhwala, Jongo, Said A., Kassim, Kamaka R., Mkindi, Catherine, Simon, Beatus, Mtoro, Ali T., Juma, Omar A., Lweno, Omar N., Gwandu, Conrad H., Bakari, Bakari M., Mbaga, Thabiti A., Milando, Florence A., Hamad, Ali, Shekalaghe, Seif A., Abdulla, Salim, Denti, Paolo, Penny, Melissa A.“…A pharmacokinetic study was conducted in adults and children over 5 years of age (6 to 10, 11 to 17, and ≥18 years of age) with uncomplicated malaria in Tanzania. The median weights for the three age groups were 20, 37.5, and 55 kg, respectively. …”
Publicado 2022
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28028por Thakar, Anup, Goyal, Mandip, Bhinde, Sagar, Chhotala, Yagnik, Panara, Kalpesh, Chaudhari, Swapnil“…BACKGROUND: Ayurveda herbal formulation AYUSH-64, proven to treat malaria and influenza-like illness in india was repurposed for COVID-19 patients considering preliminary evidances, however, scientific data was not available. …”
Publicado 2022
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28029“…After a flood, children experience post-traumatic stress disorder, respiratory illness, educational problems, diarrhea, malaria, child abuse, and lack of health facilities. …”
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28030“…It has been used to treat different ailments ranging from respiratory tract infections, urinary tract infections, malaria, diabetes, hypertension, dermatological conditions, arthritis, gastrointestinal disorders, fever, sexually transmitted diseases, and infertility. …”
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28031por Singab, Abdel Nasser B., Mostafa, Nada M., Elkhawas, Yasmin A., Al-Sayed, Eman, Bishr, Mokhtar M., Elissawy, Ahmed M., Elnaggar, Mohamed S., Fawzy, Iten M., Salama, Osama M., Tsai, Yi-Hong, Chang, Fang-Rong“…Culex pipiens mosquitoes are vectors to many viruses and can transmit diseases such as filariasis and avian malaria. The present study evaluated the larvicidal activity of marine-derived endophytic fungi Aspergillus nomius and Aspergillus flavus from the soft coral Sarcophyton ehrenbergi along with two known cyclodepsipeptide compounds, scopularide A (1) and B (2), isolated from A. flavus extract, against third-instar larvae of C. pipiens, using distilled water as a negative control and toosenedanin as a positive control. …”
Publicado 2022
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28032“…Most of these features of transcriptional variability are preserved in isogenic parasite cell populations (albeit with a lesser amplitude) suggesting a role of epigenetic factors in cell-to-cell transcriptional variations in human malaria parasites. Lastly, we apply quantitative RT-PCR and RNA-FISH approach and confirm stochastic expression of key invasion genes, such as, msp1, msp3, msp7, eba181 and ama1 which represent prime candidates for invasion-blocking vaccines.…”
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28033por Silva, M., Malmberg, M., Otienoburu, S. D., Björkman, A., Ngasala, B., Mårtensson, A., Gil, J. P., Veiga, M. I.“…Methods: In a clinical trial performed in Tanzania, we explored the pfmdr1 and pfcrt transcription levels from 48 patients with uncomplicated P. falciparum malaria infections who underwent treatment with artemether-lumefantrine (AL). …”
Publicado 2022
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28034“…Less than half took folic acid, B-complex vitamins and ferrous sulphate twice daily, 36.9% had Anaemia (27.8% mild; 5.3% moderate; and 3.8% severe anaemia) and 76.8% had malaria. There was significant relationships between iron rich consumption, supplement intake especially iron supplement and prevalence of anaemia among pregnant women attending antenatal clinic in this study (P < 0.05). …”
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28035por Cai, Haijian, Fan, Shiqian, Cai, Luqiong, Zhu, Lin, Zhao, Zhucheng, Li, Yaozhe, Yao, Yizhu, Huang, Xiaoying, Wang, Liangxing“…Dihydroartemisinin (DHA) is an active form of artemisinin extracted from the traditional Chinese medicine Artemisia annua, which is used to treat malaria. Previous studies have shown that DHA has a therapeutic effect on pulmonary hypertension (PH), but its specific mechanism has not been fully elucidated. …”
Publicado 2022
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28036por Khan, Ali, Pervaiz, Aini, Ansari, Bushra, Ullah, Riaz, Shah, Syed Muhammad Mukarram, Khan, Haroon, Saeed Jan, Muhammad, Hussain, Fida, Ijaz Khan, Mohammad, Albadrani, Ghadeer M., Altyar, Ahmed E., Abdel-Daim, Mohamed M.“…It is locally known as khadang and is used for the treatment of different diseases such as analgesic, tonic, diuretic, malaria, inflammation, allergy, infections, cancer, diabetes, and lipid peroxidative. …”
Publicado 2022
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28037por Dénou, Adama, Togola, Adiaratou, Inngjerdingen, Kari Tvete, Moussavi, Nastaran, Rise, Frode, Zou, Yuan Feng, Dafam, Dalen G., Nep, Elijah I., Ahmed, Abubakar, Alemika, Taiwo E., Diallo, Drissa, Sanogo, Rokia, Paulsen, Berit Smestad“…(Papaveraceae) traditionally used against malaria in Mali are limited to its low-mass compounds activities, and little information on its bioactive polysaccharides is available. …”
Publicado 2022
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28038por Treleaven, Emily, Whidden, Caroline, Cole, Faith, Kayentao, Kassoum, Traoré, Mohamed Bana, Diakité, Djoumé, Sidibé, Seydou, Lin, Tracy Kuo, Boettiger, David, Cissouma, Souleymane, Sanogo, Vincent, Padian, Nancy, Johnson, Ari, Liu, Jenny“…While children with symptoms indicative of pneumonia and malaria were more likely to receive any care, suggesting mothers and caregivers recognised potentially severe illness, multiple barriers to care contributed to delays and low utilisation of qualified providers, illustrating the need for improved consideration of barriers.…”
Publicado 2021
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28039por Täubel, Jӧrg, Lorch, Ulrike, Ferber, Georg, Spencer, Christopher S., Freier, Anne, Coates, Simon, El Gaaloul, Myriam, Donini, Cristina, Chughlay, Mohamed Farouk, Chalon, Stephan“…P218 is an aminopyridine that inhibits dihydrofolate reductase being developed as a malaria chemoprotective drug. Assessing the effect of new compounds on cardiac intervals is key during early drug development to determine their cardiac safety. …”
Publicado 2021
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28040“…We evaluate their properties by simulation and apply the methods to a trial of seasonal malaria chemoprevention. The approximately unbiased estimators are practically unbiased and their confidence intervals usually have coverage probability close to the nominal level; the asymptotically unbiased estimators perform well when the number of clusters is approximately 32 or more per trial arm. …”
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