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28121por Tauchen, Jan, Frankova, Adela, Manourova, Anna, Valterova, Irena, Lojka, Bohdan, Leuner, Olga“…Garcinia kola is used in treatment of numerous diseases, including gastric disorders, bronchial diseases, fever, malaria and is used to induce a stimulating and aphrodisiac effect. …”
Publicado 2023
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28122“…Recent results have shown that the human malaria-resistant hemoglobin S mutation originates de novo more frequently in the gene and in the population where it is of adaptive significance, namely, in the hemoglobin subunit beta gene compared to the nonresistant but otherwise identical 20A[Formula: see text] T mutation in the hemoglobin subunit delta gene, and in sub-Saharan Africans, who have been subject to intense malarial pressure for many generations, compared to northern Europeans, who have not. …”
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28123“…Stool and blood film examinations were performed to detect intestinal and malaria parasites, respectively. Data were entered into EpiData 3.1 and analyzed by Stata 14.0 software. …”
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28124por Si, Wenwen, Fang, Chuantao, Liu, Chuang, Yin, Meng, Xu, Wenyue, Li, Yanna, Yan, Xiaoli, Shen, Yujuan, Cao, Jianping, Sun, Jun“…These results suggest that Babesia spp. lack a similar mechanism to that of malaria parasites through which the haem or iron in hemoglobin is utilized, and that this likely leads to their insensitivity to artemisinin. …”
Publicado 2023
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28125por Xia, Ming, Vago, Frank, Han, Ling, Huang, Pengwei, Nguyen, Linh, Boons, Geert-Jan, Klassen, John S, Jiang, Wen, Tan, Ming“…INTRODUCTION: Malaria is a devastating infectious illness caused by protozoan Plasmodium parasites. …”
Publicado 2023
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28126por Mudassar, Faiqa, Chang, Cecilia, Ing, Prunella, Nguyen, Sandy, Cook, Kristina M, Warnken, Zachary N, O’Neill, Geraldine, Shen, Han, Hau, Eric“…The most promising OCR inhibitor identified was atovaquone, a drug used for treatment of pneumocystis pneumonia and malaria. We found that atovaquone inhibited mitochondrial metabolism of DMG cells by specifically targeting the mitochondrial complex III. …”
Publicado 2023
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28127por Andia-Biraro, Irene, Baluku, Joseph Baruch, Olum, Ronald, Bongomin, Felix, Kyazze, Andrew Peter, Ninsiima, Sandra, Ssekamatte, Phillip, Kibirige, Davis, Biraro, Samuel, Seremba, Emmanuel, Kabugo, Charles“…There were significantly fewer diagnostic tests performed in 2020 for malaria, tuberculosis, and diabetes. Overall, 649 (17.3%) patients died. …”
Publicado 2023
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28128“…Chi-square tests were performed to assess associations between demographic variables (age, gender, education, village) and respondents’ knowledge and information of the projects, Malaria and Bilharzia in Southern Africa and Tackling Infections to Benefit Africa as well as their participation. …”
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28129“…Gene drive-modified mosquitoes (GDMMs) are proposed as new tools for control and elimination of malaria and other mosquito-borne diseases, and promising results have been observed from testing conducted in containment. …”
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28130por Lucky, Amuza Byaruhanga, Wang, Chengqi, Liu, Min, Liang, Xiaoying, Min, Hui, Fan, Qi, Siddiqui, Faiza Amber, Adapa, Swamy Rakesh, Li, Xiaolian, Jiang, Rays H. Y., Chen, Xiaoguang, Cui, Liwang, Miao, Jun“…Protein arginine methyltransferases (PRMTs) regulate many important cellular processes, such as transcription and RNA processing in model organisms but their functions in human malaria parasites are not elucidated. Here, we characterize PfPRMT5 in Plasmodium falciparum, which catalyzes symmetric dimethylation of histone H3 at R2 (H3R2me2s) and R8, and histone H4 at R3 in vitro. …”
Publicado 2023
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28131por Prompiram, Phirom, Poltep, Kanaporn, Chaisilp, Nattarun, Chakritbudsabong, Warunya, Buamas, Supakit, Rungarunlert, Sasitorn“…The Plasmodium parasites infecting these White-breasted Waterhens previously caused severe avian malaria in other host species. The unidentified Plasmodium species had rarely been documented, although it was reported in the Culex vector and was possibly associated with specialist parasites either as host or habitat. …”
Publicado 2023
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28132por Cappelli, Alessia, Damiani, Claudia, Capone, Aida, Bozic, Jovana, Mensah, Priscilla, Clementi, Emanuela, Spaccapelo, Roberta, Favia, Guido, Ricci, Irene“…Antiplasmodial effects of W. anomalus have been shown in the gut of the female malaria vector mosquito Anopheles stephensi. This discovery highlights the potential of utilizing yeast as a promising tool for symbiotic control of mosquito-borne diseases. …”
Publicado 2023
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28133por Sidiki, Ngouyamsa Nsapkain Aboubakar, Nadia, Noumedem Anangmo Christelle, Cedric, Yamssi, Guy-Armand, Gamago Nkadeu, Sandra, Tientcheu Noutong Jemimah, Kevin, Tako Djimefo Alex, Azizi, Mounvera Abdel, Payne, Vincent Khan“…BACKGROUND: Reduction of oxidative stress during malaria infection is considered as being of great benefit so long as treatment and drug development approaches are concerned. …”
Publicado 2023
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28134por Steinbronn, Claire, Chhonker, Yashpal S., Stewart, Jenell, Leingang, Hannah, Heller, Kate B., Krows, Meighan L., Paasche‐Orlow, Michael, Bershteyn, Anna, Stankiewicz Karita, Helen C., Agrawal, Vaidehi, Laufer, Miriam, Landovitz, Raphael, Wener, Mark, Murry, Daryl J., Johnston, Christine, Barnabas, Ruanne V., Arnold, Samuel L. M.“…Hydroxychloroquine (HCQ) is Food and Drug Administration (FDA)‐approved for malaria, systemic and chronic discoid lupus erythematosus, and rheumatoid arthritis. …”
Publicado 2023
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28135An evaluation of truncated birth histories for the rapid measurement of fertility and child survival“…To reduce the length of the interview, some surveys resort to truncated birth histories (TBHs), where questions are asked only on recent births. METHODS: We used 32 Malaria Indicator Surveys that included TBHs from 18 countries in sub-Saharan Africa. …”
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28136por B. Henry, Noëlie, Soulama, Issiaka, S. Sermé, Samuel, Bolscher, Judith M., T. G. Huijs, Tonnie, S. Coulibaly, Aboubacar, Sombié, Salif, Ouédraogo, Nicolas, Diarra, Amidou, Zongo, Soumanaba, Guelbéogo, Wamdaogo M., Nébié, Issa, Sirima, Sodiomon B., Tiono, Alfred B., Pietro, Alano, Collins, Katharine A., Dechering, Koen J., Bousema, Teun“…Antimalarial drugs that can block the transmission of Plasmodium gametocytes to mosquito vectors would be highly beneficial for malaria elimination efforts. Identifying transmission-blocking drugs currently relies on evaluation of their activity against gametocyte-producing laboratory parasite strains and would benefit from a testing pipeline with genetically diverse field isolates. …”
Publicado 2023
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28137por Mateso, Guy-Quesney, Makali, Samuel, Shamamba, Ashuza, Ntaboba, Balola, Urbain, Victoire, Eric, Musingilwa, Murhabazi, Emmanuel, Mihigo, Martine, Mwene-Batu, Pacifique, Kabego, Landry, Baguma, Marius“…The most common causes of NTC were stroke (25.7%), acute metabolic complications of diabetes (21.9%), and primary brain infections (meningoencephalitis, 16.0%; and cerebral malaria, 14.2%). The NTC-related in-hospital mortality rate was 35.2%. …”
Publicado 2023
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28138por Akankwasa, Edith, Kamya, Willy, Sendijja, Moses, Mudoola, Janet, Lwenge, Mathias, Onzima, Robert Anguyo DDM, Kasozi, Daniel, Byansi, Peter, Katongole, Simon Peter“…All districts achieved the 80% coverage target in ANC first visit, mothers who received at least two doses of Fansidar for intermittent preventive treatment of malaria in pregnancy, and mothers with knowledge of the action to take in case they suspect childhood disability. …”
Publicado 2023
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28139por Amo, Laura, Kole, Hemanta K., Scott, Bethany, Qi, Chen-Feng, Krymskaya, Ludmila, Wang, Hongsheng, Miller, Louis H., Janse, Chris J., Bolland, Silvia“…The host response against infection with Plasmodium commonly raises self-reactivity as a side effect, and antibody deposition in kidney has been cited as a possible cause of kidney injury during severe malaria. In contrast, animal models show that infection with the parasite confers long-term protection from lethal lupus nephritis initiated by autoantibody deposition in kidney. …”
Publicado 2023
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28140por Xie, Stanley C., Wang, Yinuo, Morton, Craig J., Metcalfe, Riley D., Dogovski, Con, Pasaje, Charisse Flerida A., Dunn, Elyse, Luth, Madeline R, Kumpornsin, Krittikorn, Istvan, Eva S, Park, Joon Sung, Fairhurst, Kate J., Ketprasit, Nutpakal, Yeo, Tomas, Yildirim, Okan, Bhebhe, Mathamsanqa N., Klug, Dana M., Rutledge, Peter J., Godoy, Luiz C., Dey, Sumanta, De Souza, Mariana Laureano, Siqueira-Neto, Jair L., Du, Yawei, Puhalovich, Tanya, Amini, Mona, Shami, Gerry, Loesbanluechai, Duangkamon, Nie, Shuai, Williamson, Nicholas, Jana, Gouranga P., Maity, Bikash C., Thomson, Patrick, Foley, Thomas, Tan, Derek S., Niles, Jacquin C, Han, Byung Woo, Goldberg, Daniel E, Burrows, Jeremy, Fidock, David A., Lee, Marcus C.S., Winzeler, Elizabeth A., Griffin, Michael D. W., Todd, Matthew H., Tilley, Leann“…Malaria poses an enormous threat to human health. …”
Publicado 2023
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