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28201por Matee, Mecky I, Manyando, Christine, Ndumbe, Peter M, Corrah, Tumani, Jaoko, Walter G, Kitua, Andrew Y, Ambene, Herman PA, Ndounga, Mathieu, Zijenah, Lynn, Ofori-Adjei, David, Agwale, Simon, Shongwe, Steven, Nyirenda, Thomas, Makanga, Michael“…It is a partnership of 14 European Union (EU) member states, Norway, Switzerland, and Developing Countries, formed to fund acceleration of new clinical trial interventions to fight the human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS), malaria and tuberculosis (TB) in the sub-Saharan African region. …”
Publicado 2009
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28202por Ly, Sowath, Buchy, Philippe, Heng, Nay Yim, Ong, Sivuth, Chhor, Nareth, Bourhy, Hervé, Vong, Sirenda“…In 2007, the estimated rabies related mortality exceeded that of malaria and that of dengue. A national rabies control program is needed to improve surveillance and access to PEP, and to initiate vaccination campaigns in dogs.…”
Publicado 2009
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28203por Flueck, Christian, Bartfai, Richard, Volz, Jennifer, Niederwieser, Igor, Salcedo-Amaya, Adriana M., Alako, Blaise T. F., Ehlgen, Florian, Ralph, Stuart A., Cowman, Alan F., Bozdech, Zbynek, Stunnenberg, Hendrik G., Voss, Till S.“…Epigenetic processes are the main conductors of phenotypic variation in eukaryotes. The malaria parasite Plasmodium falciparum employs antigenic variation of the major surface antigen PfEMP1, encoded by 60 var genes, to evade acquired immune responses. …”
Publicado 2009
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28204“…Various high throughput studies indicate that STK35 could be involved in various human diseases such as colorectal cancer and malaria. METHODOLOGY/PRINCIPAL FINDINGS: In this study, we found that the previously published coding sequence of the STK35 gene is incomplete. …”
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28205por Nwane, Philippe, Etang, Josiane, Chouaibou, Mouhamadou, Toto, Jean Claude, Kerah-Hinzoumbé, Clément, Mimpfoundi, Rémy, Awono-Ambene, Herman Parfait, Simard, Frédéric“…In certain insect species, particularly the malaria vector Anopheles gambiae, resistance to this class of insecticides is a source of great concern and needs to be monitored in order to sustain the efficacy of vector control operations in the fields. …”
Publicado 2009
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28206por Steenkeste, Nicolas, Dillies, Marie-Agnès, Khim, Nimol, Sismeiro, Odile, Chy, Sophy, Lim, Pharath, Crameri, Andreas, Bouchier, Christiane, Mercereau-Puijalon, Odile, Beck, Hans-Peter, Imwong, Mallika, Dondorp, Arjen M, Socheat, Duong, Rogier, Christophe, Coppée, Jean-Yves, Ariey, Frédéric“…The FlexiChip package is a promising tool for use in poor resource settings of malaria endemic countries.…”
Publicado 2009
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28207Modeling trends of health and health related indicators in Ethiopia (1995-2008): a time-series study“…There was a reversal of malaria parasite prevalence in 1999 E.C from Plasmodium Falciparum to Plasmodium Vivax. …”
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28208por Bukhari, Tullu, Middelman, Anthonieke, Koenraadt, Constantianus JM, Takken, Willem, Knols, Bart GJ“…BACKGROUND: Entomopathogenic fungi have shown great potential for the control of adult malaria vectors. However, their ability to control aquatic stages of anopheline vectors remains largely unexplored. …”
Publicado 2010
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28209por Grüber, Ardina, Manimekalai, Malathy S. S., Balakrishna, Asha M., Hunke, Cornelia, Jeyakanthan, Jeyaraman, Preiser, Peter R., Grüber, Gerhard“…BACKGROUND: Invasion of the red blood cells (RBC) by the merozoite of malaria parasites involves a large number of receptor ligand interactions. …”
Publicado 2010
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28210por Joubert, Bonnie R., Franceschini, Nora, Mwapasa, Victor, North, Kari E., Meshnick, Steven R.“…Higher CCR5 expression was observed for mothers with malaria but was not statistically significant (β = 0.37, 95% CI = −0.43, 1.18). …”
Publicado 2010
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28211por Flueck, Christian, Bartfai, Richard, Niederwieser, Igor, Witmer, Kathrin, Alako, Blaise T. F., Moes, Suzette, Bozdech, Zbynek, Jenoe, Paul, Stunnenberg, Hendrik G., Voss, Till S.“…The heterochromatic environment and physical clustering of chromosome ends at the nuclear periphery provide a functional and structural framework for antigenic variation and evolution of subtelomeric virulence gene families in the malaria parasite Plasmodium falciparum. While recent studies assigned important roles for reversible histone modifications, silent information regulator 2 and heterochromatin protein 1 (PfHP1) in epigenetic control of variegated expression, factors involved in the recruitment and organization of subtelomeric heterochromatin remain unknown. …”
Publicado 2010
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28212por Barros, Fernando C, Bhutta, Zulfiqar Ahmed, Batra, Maneesh, Hansen, Thomas N, Victora, Cesar G, Rubens, Craig E“…The following are supported by moderate- to high-quality evidence and strongly recommended for LMICs: • Two interventions prevent preterm births—smoking cessation and progesterone • Eight interventions prevent stillbirths—balanced protein energy supplementation, screening and treatment of syphilis, intermittant presumptive treatment for malaria during pregnancy, insecticide-treated mosquito nets, birth preparedness, emergency obstetric care, cesarean section for breech presentation, and elective induction for post-term delivery • Eleven interventions improve survival of preterm newborns—prophylactic steroids in preterm labor, antibiotics for PROM, vitamin K supplementation at delivery, case management of neonatal sepsis and pneumonia, delayed cord clamping, room air (vs. 100% oxygen) for resuscitation, hospital-based kangaroo mother care, early breastfeeding, thermal care, and surfactant therapy and application of continued distending pressure to the lungs for respiratory distress syndrome CONCLUSION: The research paradigm for discovery science and intervention development must be balanced to address prevention as well as improve morbidity and mortality in all settings. …”
Publicado 2010
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28213por Vinayak, Sumiti, Alam, Md Tauqeer, Mixson-Hayden, Tonya, McCollum, Andrea M., Sem, Rithy, Shah, Naman K., Lim, Pharath, Muth, Sinuon, Rogers, William O., Fandeur, Thierry, Barnwell, John W., Escalante, Ananias A., Wongsrichanalai, Chansuda, Ariey, Frederick, Meshnick, Steven R., Udhayakumar, Venkatachalam“…The Thailand-Cambodia border is the epicenter for drug-resistant falciparum malaria. Previous studies have shown that chloroquine (CQ) and pyrimethamine resistance originated in this region and eventually spread to other Asian countries and Africa. …”
Publicado 2010
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28214“…CONCLUSIONS: Product approvals for neglected diseases have increased, though progress has been uneven, with malaria appearing to benefit most in the short run from increased funding, while less success has been booked in other disease categories. …”
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28215por Joubert, Bonnie R, Lange, Ethan M, Franceschini, Nora, Mwapasa, Victor, North, Kari E, Meshnick, Steven R“…METHODS: We conducted a nested case-control study of HIV MTCT using infants of HIV(+) mothers, drawn from a cohort study of malaria and HIV in pregnancy in Blantyre, Malawi. …”
Publicado 2010
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28216“…Most respondents did not recognize the symptoms of DM when falling ill but related the problems to other diseases, e.g. HIV, malaria etc. Limited knowledge about DM and the body was indicated. …”
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28217por Abuya, Timothy, Amin, Abdinasir, Molyneux, Sassy, Akhwale, Willis, Marsh, Vicki, Gilson, Lucy“…ABSTRACT: BACKGROUND: The home-management of malaria strategy seeks to improve prompt and effective anti-malarial drug use through the informal sector, with a potential channel being the Private Medicine Retailers (PMRs). …”
Publicado 2010
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28218“…Radiation-attenuated Plasmodium sporozoites (RAS) are the only vaccine shown to induce sterilizing protection against malaria in both humans and rodents. Importantly, these “whole-parasite” vaccines are currently under evaluation in human clinical trials. …”
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28219por Ahoua Alou, Ludovic P, Koffi, Alphonsine A, Adja, Maurice A, Tia, Emmanuel, Kouassi, Philippe K, Koné, Moussa, Chandre, Fabrice“…BACKGROUND: The spread of pyrethroid resistance in Anopheles gambiae s.s. is a critical issue for malaria vector control based on the use of insecticide-treated nets. …”
Publicado 2010
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28220“…(3) the degree to which those at highest risk of malaria use the most protective nets. METHODS: Data from the 2006 TNVS household survey were analysed to assess within-household distribution of net use. …”
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