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28361por Waisberg, Michael, Molina-Cruz, Alvaro, Mizurini, Daniella M., Gera, Nidhi, Sousa, Beatriz C., Ma, Dongying, Leal, Ana C., Gomes, Tainá, Kotsyfakis, Michalis, Ribeiro, José M. C., Lukszo, Jan, Reiter, Karine, Porcella, Stephen F., Oliveira, Carlo J., Monteiro, Robson Q., Barillas-Mury, Carolina, Pierce, Susan K., Francischetti, Ivo M. B.“…BACKGROUND: Invasion of mosquito salivary glands (SGs) by Plasmodium falciparum sporozoites is an essential step in the malaria life cycle. How infection modulates gene expression, and affects hematophagy remains unclear. …”
Publicado 2014
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28362por Hakizimana, Emmanuel, Cyubahiro, Beatus, Rukundo, Alphonse, Kabayiza, Allan, Mutabazi, Alphonse, Beach, Raymond, Patel, Roopal, Tongren, Jon E, Karema, Corine“…BACKGROUND: To validate assumptions about the length of the distribution–replacement cycle for long-lasting insecticidal nets (LLINs) in Rwanda, the Malaria and other Parasitic Diseases Division, Rwanda Ministry of Health, used World Health Organization methods to independently confirm the three-year LLIN serviceable life span recommendation of WHO. …”
Publicado 2014
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28363por Chimberengwa, Pugie Tawanda, Masuka, Nyasha, Gombe, Notion Tafara, Bangure, Donewell, Tshimanga, Mufuta, Takundwa, Lucia“…The provincial health team adopted as on-going activities, the inclusion of schistosomiasis prevention and control in malaria pre-elimination activities.…”
Publicado 2014
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28364por Mugeni, Catherine, Levine, Adam C, Munyaneza, Richard M, Mulindahabi, Epiphanie, Cockrell, Hannah C, Glavis-Bloom, Justin, Nutt, Cameron T, Wagner, Claire M, Gaju, Erick, Rukundo, Alphonse, Habimana, Jean Pierre, Karema, Corine, Ngabo, Fidele, Binagwaho, Agnes“…Community health workers in each of Rwanda's nearly 15,000 villages were trained in iCCM and equipped for empirical diagnosis and treatment of pneumonia, diarrhea, and malaria; for malnutrition surveillance; and for comprehensive reporting and referral services. …”
Publicado 2014
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28365por Carrión Martín, Antonio Isidro, Bil, Karla, Salumu, Papy, Baabo, Dominique, Singh, Jatinder, Kik, Corry, Lenglet, Annick“…The most frequently reported cause of death was fever/malaria 34.1% (CI95%: 25.4–42.9). Thirteen deaths were due to intentional violence. …”
Publicado 2014
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28366por Mosha, Dominic, Mazuguni, Festo, Mrema, Sigilbert, Abdulla, Salim, Genton, Blaise“…Artemether-lumefantrine (AL) was the most used antimalarial for treating illness by nearly 3/4 compared to other groups of malaria drugs. Overall, antimalarial and antibiotic exposures in pregnancy were not significantly associated with adverse pregnancy outcome. …”
Publicado 2014
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28367“…It is important to upgrade providers’ educational level and institute prevention of diseases like malaria to reduce the level of prescribed drug use during pregnancy.…”
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28368“…BACKGROUND: The development of malaria vaccine has been hindered by the allele-specific responses produced by some parasite antigens’ high genetic diversity. …”
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28369por Schousboe, Mette L, Ranjitkar, Samir, Rajakaruna, Rupika S, Amerasinghe, Priyanie H, Konradsen, Flemming, Morales, Francisco, Ord, Rosalynn, Pearce, Richard, Leslie, Toby, Rowland, Mark, Gadalla, Nahla, Bygbjerg, Ib C, Alifrangis, Michael, Roper, Cally“…BACKGROUND: Even though Plasmodium vivax has the widest worldwide distribution of the human malaria species and imposes a serious impact on global public health, the investigation of genetic diversity in this species has been limited in comparison to Plasmodium falciparum. …”
Publicado 2014
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28370por Raphemot, Rene, Rouhier, Matthew F., Swale, Daniel R., Days, Emily, Weaver, C. David, Lovell, Kimberly M., Konkel, Leah C., Engers, Darren W., Bollinger, Sean F., Hopkins, Corey, Piermarini, Peter M., Denton, Jerod S.“…Vector-borne diseases such as dengue fever and malaria, which are transmitted by infected female mosquitoes, affect nearly half of the world's population. …”
Publicado 2014
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28371por Rai, Ragini, Zhu, Lei, Chen, Haifen, Gupta, Archana Patkar, Sze, Siu Kwan, Zheng, Jie, Ruedl, Christiane, Bozdech, Zbynek, Featherstone, Mark“…BACKGROUND: Over the course of its intraerythrocytic developmental cycle (IDC), the malaria parasite Plasmodium falciparum tightly orchestrates the rise and fall of transcript levels for hundreds of genes. …”
Publicado 2014
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28372por Shah, Shivang S, Macharia, Alex, Makale, Johnstone, Uyoga, Sophie, Kivinen, Katja, Craik, Rachel, Hubbart, Christina, Wellems, Thomas E, Rockett, Kirk A, Kwiatkowski, Dominic P, Williams, Thomas N“…BACKGROUND: The relationship between glucose-6-phosphate dehydrogenase (G6PD) deficiency and clinical phenomena such as primaquine-sensitivity and protection from severe malaria remains poorly defined, with past association studies yielding inconsistent and conflicting results. …”
Publicado 2014
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28373por Lobo, Elsa, de Sousa, Bruno, Rosa, Soraia, Figueiredo, Paula, Lobo, Lis, Pateira, Sara, Fernandes, Natercia, Nogueira, Fatima“…BACKGROUND: Mozambique implemented artemisinin-based combinations therapy (ACT) using artemether-lumefantrine (AL) as the first-line treatment for uncomplicated malaria in 2009. AL remains highly efficacious, but widespread use may soon facilitate emergence of artemisinin tolerance/resistance. …”
Publicado 2014
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28374por Pandey, Rajan, Mohmmed, Asif, Pierrot, Christine, Khalife, Jamal, Malhotra, Pawan, Gupta, Dinesh“…Reversible protein phosphorylation/dephosphorylation process, which involves kinases as well as phosphatases, represents an important regulatory mechanism for diverse pathways and systems in all organisms including human malaria parasite, Plasmodium falciparum. Earlier analysis on P. falciparum protein-phosphatome revealed presence of 34 phosphatases in Plasmodium genome. …”
Publicado 2014
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28375“…With reference to the Global Fund to Fight HIV/AIDS, Tuberculosis and Malaria, this paper contributes to discussions on accountability by mapping out key elements of the concept and how it is put into practice, where different types of accountability battle for recognition and legitimacy. …”
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28376por Dantur Juri, María J, Moreno, Marta, Prado Izaguirre, Mónica J, Navarro, Juan C, Zaidenberg, Mario O, Almirón, Walter R, Claps, Guillermo L, Conn, Jan E“…BACKGROUND: Anopheles pseudopunctipennis is an important malaria vector in the Neotropical region and the only species involved in Plasmodium transmission in the Andean foothills. …”
Publicado 2014
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28377“…The programs train lay community health workers to assess, classify and treat uncomplicated cases of pneumonia with antibiotics, malaria with antimalarial drugs and diarrhea with Oral Rehydration Salts (ORS) and zinc. …”
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28378por Pombi, Marco, Jacobs, Frans, Verhulst, Niels O, Caputo, Beniamino, della Torre, Alessandra, Takken, Willem“…We compared the attractiveness of this blend to that of the Mbita (MB5) lure, a new synthetic blend of proven efficiency in attracting Afrotropical malaria vectors, and evaluated the additional effect of CO(2) to the two odour baits. …”
Publicado 2014
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28379por Gurdasani, Deepti, Carstensen, Tommy, Tekola-Ayele, Fasil, Pagani, Luca, Tachmazidou, Ioanna, Hatzikotoulas, Konstantinos, Karthikeyan, Savita, Iles, Louise, Pollard, Martin O., Choudhury, Ananyo, Ritchie, Graham R. S., Xue, Yali, Asimit, Jennifer, Nsubuga, Rebecca N., Young, Elizabeth H., Pomilla, Cristina, Kivinen, Katja, Rockett, Kirk, Kamali, Anatoli, Doumatey, Ayo P., Asiki, Gershim, Seeley, Janet, Sisay-Joof, Fatoumatta, Jallow, Muminatou, Tollman, Stephen, Mekonnen, Ephrem, Ekong, Rosemary, Oljira, Tamiru, Bradman, Neil, Bojang, Kalifa, Ramsay, Michele, Adeyemo, Adebowale, Bekele, Endashaw, Motala, Ayesha, Norris, Shane A., Pirie, Fraser, Kaleebu, Pontiano, Kwiatkowski, Dominic, Tyler-Smith, Chris, Rotimi, Charles, Zeggini, Eleftheria, Sandhu, Manjinder S.“…We identify new loci under selection, including loci related to malaria susceptibility and hypertension. We show that modern imputation panels (sets of reference genotypes from which unobserved or missing genotypes in study sets can be inferred) can identify association signals at highly differentiated loci across populations in sub-Saharan Africa. …”
Publicado 2014
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28380por Mohd Abd Razak, Mohd Ridzuan, Afzan, Adlin, Ali, Rosnani, Amir Jalaluddin, Nur Fasihah, Wasiman, Mohd Isa, Shiekh Zahari, Siti Habsah, Abdullah, Noor Rain, Ismail, Zakiah“…BACKGROUND: The development of resistant to current antimalarial drugs is a major challenge in achieving malaria elimination status in many countries. Therefore there is a need for new antimalarial drugs. …”
Publicado 2014
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