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28501por Li, Bo, Sun, Zhiqiang, Li, Xiaohan, Li, Xiaoxi, Wang, Han, Chen, Weijiao, Chen, Peng, Qiao, Mengran, Mao, Yuanli“…A combination of both antigens might be a more reliable approach for the diagnosis of malaria.…”
Publicado 2017
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28502por Coetzee, Nanika, Sidoli, Simone, van Biljon, Riëtte, Painter, Heather, Llinás, Manuel, Garcia, Benjamin A., Birkholtz, Lyn-Marie“…Collectively, this data provides the most accurate, complete and comparative chromatin proteomic analyses of the entire life cycle development of malaria parasites. A substantial association between histone PTMs and stage-specific transition provides insights into the intricacies characterising Plasmodial developmental biology.…”
Publicado 2017
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28503por Duke, Trevor, Hwaihwanje, Ilomo, Kaupa, Magdalynn, Karubi, Jonah, Panauwe, Doreen, Sa’avu, Martin, Pulsan, Francis, Prasad, Peter, Maru, Freddy, Tenambo, Henry, Kwaramb, Ambrose, Neal, Eleanor, Graham, Hamish, Izadnegahdar, Rasa“…BACKGROUND: Pneumonia is the largest cause of child deaths in Papua New Guinea (PNG), and hypoxaemia is the major complication causing death in childhood pneumonia, and hypoxaemia is a major factor in deaths from many other common conditions, including bronchiolitis, asthma, sepsis, malaria, trauma, perinatal problems, and obstetric emergencies. …”
Publicado 2017
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28504“…BACKGROUND: Malaria during pregnancy is associated with poor maternal and pregnancy outcome and the World Health Organization recommends the administration of intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) and distribution of insecticide-treated mosquito nets (ITNs) to all pregnant women attending antenatal care (ANC) services. …”
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28505por González, Raquel, Rupérez, María, Sevene, Esperança, Vala, Anifa, Maculuve, Sónia, Bulo, Helder, Nhacolo, Arsénio, Mayor, Alfredo, Aponte, John J., Macete, Eusébio, Menendez, Clara“…No differences were found in mean birth weight, malaria, prematurity and maternal and neonatal deaths between groups. …”
Publicado 2017
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28506por Lempereur, Laetitia, Larcombe, Stephen D., Durrani, Zeeshan, Karagenc, Tulin, Bilgic, Huseyin Bilgin, Bakirci, Serkan, Hacilarlioglu, Selin, Kinnaird, Jane, Thompson, Joanne, Weir, William, Shiels, Brian“…The most important disease syndromes caused by these parasites are malaria, babesiosis and theileriosis. Strategies for control often target parasite stages in the mammalian host that cause disease, but this can result in reservoir infections that promote pathogen transmission and generate economic loss. …”
Publicado 2017
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28507por Shen, Hai-Mo, Chen, Shen-Bo, Wang, Yue, Xu, Bin, Abe, Eniola Michael, Chen, Jun-Hu“…CONCLUSIONS: This study suggests that greater genetic diversity in P. vivax from CMB area and positive selection signals in invasion and drug resistance genes are consistent with the history of drug use during malaria elimination programme in CMB area. Furthermore, this result also demonstrates that haplotype-based detecting selection can assist the genome-wide methods to identify the determinants of P. vivax diversity. …”
Publicado 2017
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28508“…This comparative analyses could provide important clues for the development of new strategies to prevent and treat malaria in humans, however, the number of functionally annotated proteins is still low for all Plasmodium species. …”
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28509por Ayenan, Mathieu Anatole Tele, Danquah, Agyemang, Ahoton, Léonard Essehou, Ofori, Kwadwo“…Pigeonpea’s stem and leaves are used for medicinal purposes to treat malaria, dizziness, measles, and eye infection. The ethnic group and the locality of residence of farmers influenced on the use of pigeonpea for medicinal purposes (P < 0.01). …”
Publicado 2017
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28510por Metwally, Nahla Galal, Tilly, Ann-Kathrin, Lubiana, Pedro, Roth, Lisa K., Dörpinghaus, Michael, Lorenzen, Stephan, Schuldt, Kathrin, Witt, Susanne, Bachmann, Anna, Tidow, Henning, Gutsmann, Thomas, Burmester, Thorsten, Roeder, Thomas, Tannich, Egbert, Bruchhaus, Iris“…The ability of the parasite Plasmodium falciparum to evade the immune system and be sequestered within human small blood vessels is responsible for severe forms of malaria. The sequestration depends on the interaction between human endothelial receptors and P. falciparum erythrocyte membrane protein 1 (PfEMP1) exposed on the surface of the infected erythrocytes (IEs). …”
Publicado 2017
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28511por Mathenge, Evan M, Misiani, Gedion O, Oulo, David O, Irungu, Lucy W, Ndegwa, Paul N, Smith, Tom A, Killeen, Gerry F, Knols, Bart GJ“…BACKGROUND: Mosquitoes sampling is an important component in malaria control. However, most of the methods used have several shortcomings and hence there is a need to develop and calibrate new methods. …”
Publicado 2005
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28512por Jennings, Mary Carol, Pradhan, Subarna, Schleiff, Meike, Sacks, Emma, Freeman, Paul A, Gupta, Sundeep, Rassekh, Bahie M, Perry, Henry B“…Seven assessments measured changes in maternal morbidity: postpartum hemorrhage, malaria or eclampsia. Of those, six reported significant decreases and one did not find a significant effect. …”
Publicado 2017
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28513por McGregor, Kathryn, Myat Min, Aung, Karunkonkowit, Noaeni, Keereechareon, Suporn, Tyrosvoutis, Mary Ellen, Tun, Nay Win, Rijken, Marcus J., Hoogenboom, Gabie, Boel, Machteld, Chotivanich, Kesinee, Nosten, François, McGready, Rose“…A recurrence rate of 2.5% (2/80) was observed in the assessable population. The presence of malaria parasites in maternal blood was not associated with GTD. …”
Publicado 2017
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28514por Lynd, Amy, Ranson, Hilary, McCall, P J, Randle, Nadine P, Black, William C, Walker, Edward D, Donnelly, Martin J“…Its occurrence in Anopheles mosquitoes may have important implications for malaria vector control especially considering the current trend for large scale pyrethroid-treated bednet programmes. …”
Publicado 2005
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28515“…The Pathogen Box from the Medicines for Malaria Venture (MMV) is a collection of 400 diverse drug-like compounds, among which 129 are known to be active against M. tuberculosis. …”
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28516por Gupta, Archana P., Zhu, Lei, Tripathi, Jaishree, Kucharski, Michal, Patra, Alok, Bozdech, Zbynek“…This is potentially a highly significant finding that suggests a regulatory connection between growth and parasite–host interaction both of which play a major role in malaria parasite virulence. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13072-017-0147-z) contains supplementary material, which is available to authorized users.…”
Publicado 2017
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28517por Villa-Pulgarín, Janny A., Gajate, Consuelo, Botet, Javier, Jimenez, Alberto, Justies, Nicole, Varela-M, Rubén E., Cuesta-Marbán, Álvaro, Müller, Ingrid, Modolell, Manuel, Revuelta, José L., Mollinedo, Faustino“…BACKGROUND: Leishmaniasis is the world’s second deadliest parasitic disease after malaria, and current treatment of the different forms of this disease is far from satisfactory. …”
Publicado 2017
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28518por Moraes, Miriam S., Budu, Alexandre, Singh, Maneesh K., Borges-Pereira, Lucas, Levano-Garcia, Julio, Currà, Chiara, Picci, Leonardo, Pace, Tomasino, Ponzi, Marta, Pozzan, Tullio, Garcia, Célia R. S.“…The malaria parasite Plasmodium falciparum is exposed, during its development, to major changes of ionic composition in its surrounding medium. …”
Publicado 2017
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28519por Rueangweerayut, Ronnatrai, Bancone, Germana, Harrell, Emma J., Beelen, Andrew P., Kongpatanakul, Supornchai, Möhrle, Jörg J., Rousell, Vicki, Mohamed, Khadeeja, Qureshi, Ammar, Narayan, Sushma, Yubon, Nushara, Miller, Ann, Nosten, François H., Luzzatto, Lucio, Duparc, Stephan, Kleim, Jörg-Peter, Green, Justin A.“…Tafenoquine is an 8-aminoquinoline under investigation for the prevention of relapse in Plasmodium vivax malaria. This open-label, dose-escalation study assessed quantitatively the hemolytic risk with tafenoquine in female healthy volunteers heterozygous for the Mahidol(487A) glucose-6-phosphate dehydrogenase (G6PD)-deficient variant versus G6PD-normal females, and with reference to primaquine. …”
Publicado 2017
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28520por Tassi Yunga, Samuel, Kayatani, Alexander K., Fogako, Josephine, Leke, Robert J. I., Leke, Rose G. F., Taylor, Diane W.“…Having cord blood Pf IgM was associated with placental malaria (adjusted OR [95% CI] = 2.37 [1.25–4.54]). …”
Publicado 2017
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