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28581por Sibson, Victoria L., Grijalva‐Eternod, Carlos S., Noura, Garba, Lewis, Julia, Kladstrup, Kwanli, Haghparast‐Bidgoli, Hassan, Skordis‐Worrall, Jolene, Colbourn, Tim, Morrison, Joanna, Seal, Andrew J.“…In both arms and samples, the baseline prevalence of GAM remained elevated at endline (p > 0.05), despite improved food security (p < 0.05), possibly driven by increased fever/malaria in children (p < 0.001). Nonfood related drivers of malnutrition, such as disease, may limit the effectiveness of UCTs plus supplementary feeding to prevent malnutrition in this context. …”
Publicado 2018
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28582por Macharia, Alex W., Mochamah, George, Uyoga, Sophie, Ndila, Carolyne M., Nyutu, Gideon, Makale, Johnstone, Tendwa, Metrine, Nyatichi, Emily, Ojal, John, Shebe, Mohammed, Awuondo, Kennedy O., Mturi, Neema, Peshu, Norbert, Tsofa, Benjamin, Scott, J. Anthony G., Maitland, Kathryn, Williams, Thomas N.“…Our study illustrates the clinical epidemiology of SCA in a malaria‐endemic environment without specific interventions. …”
Publicado 2017
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28583por Breglio, Kimberly F., Amato, Roberto, Eastman, Richard, Lim, Pharath, Sa, Juliana M., Guha, Rajarshi, Ganesan, Sundar, Dorward, David W., Klumpp-Thomas, Carleen, McKnight, Crystal, Fairhurst, Rick M., Roberts, David, Thomas, Craig, Simon, Anna Katharina“…BACKGROUND: Artemisinin-resistant Plasmodium falciparum has been reported throughout the Greater Mekong subregion and threatens to disrupt current malaria control efforts worldwide. Polymorphisms in kelch13 have been associated with clinical and in vitro resistance phenotypes; however, several studies suggest that the genetic determinants of resistance may involve multiple genes. …”
Publicado 2018
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28584por Hegemann, Arne, Alcalde Abril, Pablo, Muheim, Rachel, Sjöberg, Sissel, Alerstam, Thomas, Nilsson, Jan-Åke, Hasselquist, Dennis“…Birds infected with avian malaria-like parasites showed longer landscape movements during the stopover than uninfected individuals, and birds with double blood parasite infections departed more than 2.5 h later after sunset/sunrise suggesting shorter flight bouts. …”
Publicado 2018
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28585por Nteziyaremye, Julius, Paasi, George, Burgoine, Kathy, Sadiq Balyejjusa, Jaffer, Tegu, Crispus, Olupot-Olupot, Peter“…All study participants were promptly managed for underlying conditions and comorbidity such as malaria, bacteraemia, severe anaemia, meningitis, pneumonia, convulsions, hypoglycaemia and others. …”
Publicado 2017
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28586“…BACKGROUND: Atovaquone, a hydroxynaphthoquinone, FDA Pregnancy category C, used for the treatment and prevention of pneumocysits jirovecii pneumonia (PCP), toxoplasmosis, babesiosis and malaria has in vitro activity against Zika virus (ZIKV). …”
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28587por Fazal, Farhan, Wig, Naveet, Soneja, Manish, Mitra, Dipendra K, Panda, Sk, Satpathy, Gita, Vikram, Naval Kishore, Pandey, R M, Chaturvedi, P K“…The etiology were bacterial (three enteric fever, three tuberculosis, two scrub typhus, one Staphylococcal aureus), viral (one dengue fever, two HIV, two encephalitis), fungal (one aspergillosis, one mucormycosis, two others), parasites (three malaria, one leishmania) malignancy (two hodgkin lymphoma, one non-Hodgkins lymphoma), and unknown etiology in six patients, with >1 etiology in three patients (Figure 2). …”
Publicado 2018
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28588por Anokye, Reindolf, Acheampong, Enoch, Edusei, Anthony Kwaku, Mprah, Wisdom Kwadwo, Ofori-Amoah, Justice, Amoah, Vida Maame Kissiwaa, Arkorful, Vincent Ekow“…BACKGROUND: Anaemia is the world’s second cause of disability and it affects over half of pre-school children in developing countries and at least 30–40% in industrial countries. In poorer malaria-endemic countries, anemia is one of the commonest preventable causes of death in children under 5 years. …”
Publicado 2018
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28589“…In 20 of the 45 sub-Saharan African countries, malaria was the main contributor to post-neonatal mortality reduction, and pneumonia was the main contributor in only six countries. …”
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28590por Ajamma, Yvonne Ukamaka, Onchuru, Thomas Ogao, Ouso, Daniel O., Omondi, David, Masiga, Daniel K., Villinger, Jandouwe“…These insect-specific flaviviruses (ISFVs), which are presumably non-pathogenic to vertebrates, were found in known medically important arbovirus and malaria vectors. CONCLUSIONS: Our results suggest that not only ISFVs, but also a pathogenic arbovirus, are naturally maintained within mosquito populations by vertical transmission, even in the absence of vertebrate hosts. …”
Publicado 2018
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28591por Ceccato, Pietro, Ramirez, Bernadette, Manyangadze, Tawanda, Gwakisa, Paul, Thomson, Madeleine C.“…Analyses resulting from the combination of geographical information systems (GIS) and remote sensing have improved knowledge of climatic, environmental, and biodiversity factors influencing vector-borne diseases (VBDs) such as malaria, visceral leishmaniasis, dengue, Rift Valley fever, schistosomiasis, Chagas disease and leptospirosis. …”
Publicado 2018
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28592por Ma, Ya-Nan, Xu, Dong-Bei, Li, Ling, Zhang, Fei, Fu, Xue-Qing, Shen, Qian, Lyu, Xue-Ying, Wu, Zhang-Kuanyu, Pan, Qi-Fang, Shi, Pu, Hao, Xiao-Long, Yan, Ting-Xiang, Chen, Ming-Hui, Liu, Pin, He, Qian, Xie, Li-Hui, Zhong, Yi-Jun, Tang, Yue-Li, Zhao, Jing-Ya, Zhang, Li-Da, Sun, Xiao-Fen, Tang, Ke-Xuan“…Artemisia annua produces the valuable medicinal component, artemisinin, which is a sesquiterpene lactone widely used in malaria treatment. AaORA, a homolog of CrORCA3, which is involved in activating terpenoid indole alkaloid biosynthesis in Catharanthus roseus, is a jasmonate (JA)–responsive and trichome-specific APETALA2/ETHYLENE-RESPONSE FACTOR that plays a pivotal role in artemisinin biosynthesis. …”
Publicado 2018
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28593por Orr, Mark T., Khandhar, Amit P., Seydoux, Emilie, Liang, Hong, Gage, Emily, Mikasa, Traci, Beebe, Elyse L., Rintala, Nicholas D., Persson, Karin H., Ahniyaz, Anwar, Carter, Darrick, Reed, Steven G., Fox, Christopher B.“…This adjuvant may be widely beneficial to vaccines for which TH1 immunity is important, including tuberculosis, pertussis, and malaria.…”
Publicado 2019
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28594“…We tested redkmer with short- and long-read whole genome sequence data of Anopheles gambiae, the major vector of human malaria, in which the X-shredding paradigm was originally developed. …”
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28595“…In this study, the in vitro anti-malarial activity of five current anti-malarial drugs (artemisinin, atovaquone, chloroquine, mefloquine, and pyrimethamine) and 400 compounds from the Pathogen Box provided by the Medicines for Malaria Venture on P. falciparum parasites was characterized using the XN-30 analyzer. …”
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28596por Wang, Zhensheng, Wei, Chunyan, Hao, Xiao, Deng, Weiwei, Zhang, Lianhui, Wang, Zenglei, Wang, Heng“…The identification of ptRFs reveals a complex small RNA system manipulated by the malaria parasite, and might promote research on the function of tRFs in the pathogenesis of Plasmodium infections. …”
Publicado 2019
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28597por Shiroya-Wandabwa, Makeba, Kabue, Mark, Kasungami, Dyness, Wambua, Jonesmus, Otieno, Dan, Waka, Charles, Ngindu, Augustine, Ayuyo, Christine, Kigondu, Sanyu, Oliech, Julius, Malonza, Isaac“…The majority correctly performed four of the six steps in malaria rapid diagnostic testing. However, only 58% could draw blood correctly and 67% dispose of waste correctly after the testing. …”
Publicado 2018
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28598por Showande, Segun Johnson, Fakeye, Titilayo Oyelola, Kajula, Marena, Hokkanen, Juho, Tolonen, Ari“…BACKGROUND: Increasing use of medicinal herbs as nutritional supplements and traditional medicines for the treatment of diabetes, hypertension, hyperlipidemia, and malaria fever with conventional drugs poses possibilities of herb–drug interactions (HDIs). …”
Publicado 2018
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28599por Funck-Brentano, Christian, Bacchieri, Antonella, Valentini, Giovanni, Pace, Silvia, Tommasini, Silva, Voiriot, Pascal, Ubben, David, Duparc, Stephan, Evene, Eric, Felices, Mathieu, Corsi, Marco“…However, due to confounding factors in patients with malaria, the precise extent of this effect has been found to be highly variable among studies. …”
Publicado 2019
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28600por Laizer, Saitore, Kilonzo, Kajiru, Urasa, Sarah, Maro, Venance, Walker, Richard, Howlett, William“…Case fatality rate was highest for tetanus 71.4%, meningitis 57.1%, cerebral malaria 42.9% and CNS infections 37.1%. Seropositive patients presenting with meningitis and other CNS infections were more likely to die than seronegatives. …”
Publicado 2018
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