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28621“…Eighty-five had died from an acute illness lasting no more than three weeks, which in most cases could have been treated at community level; 50.6% died from malaria, 11.8% from HIV/AIDS, and 9.4% for each of diarrhoea and acute respiratory infections. …”
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28622por Neves, Paulo A. R., Lourenço, Bárbara H., Pincelli, Anaclara, Malta, Maíra B., Souza, Rodrigo M., Ferreira, Marcelo U., Castro, Marcia C., Cardoso, Marly A.“…Factors associated with maternal anemia were (aPR; 95% CI): maternal age < 19 years (1.18; 1.01–1.38), gestational malaria (1.22; 1.01–1.49), not taking micronutrient supplements during pregnancy (1.27; 1.01–1.62), and attending < 6 antenatal care visits (1.40; 1.15–1.70). …”
Publicado 2019
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28623por Benavente, Ernest Diez, Gomes, Ana Rita, De Silva, Jeremy Ryan, Grigg, Matthew, Walker, Harriet, Barber, Bridget E., William, Timothy, Yeo, Tsin Wen, de Sessions, Paola Florez, Ramaprasad, Abhinay, Ibrahim, Amy, Charleston, James, Hibberd, Martin L., Pain, Arnab, Moon, Robert W., Auburn, Sarah, Ling, Lau Yee, Anstey, Nicholas M., Clark, Taane G., Campino, Susana“…The zoonotic Plasmodium knowlesi parasite is the most common cause of human malaria in Malaysia. Genetic analysis has shown that the parasites are divided into three subpopulations according to their geographic origin (Peninsular or Borneo) and, in Borneo, their macaque host (Macaca fascicularis or M. nemestrina). …”
Publicado 2019
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28624por Parbey, Phyllis Atta, Tarkang, Elvis, Manu, Emmanuel, Amu, Hubert, Ayanore, Martin Amogre, Aku, Fortress Yayra, Ziema, Sorengmen Amos, Bosoka, Samuel Adolf, Adjuik, Martin, Kweku, Margaret“…Finger prick blood was collected to estimate the haemoglobin (Hb) level and thick film was prepared to determine malaria parasitaemia. Axillary temperature was measured using an +electronic thermometer and anthropometric measurements were done using a weighing scale and inelastic tape measure. …”
Publicado 2019
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28625por Chen, Yu-Xuan, Zhang, Xiao-Qi, Yu, Cheng-Gong, Huang, Shu-Ling, Xie, Ying, Dou, Xiao-Tan, Liu, Wen-Jia, Zou, Xiao-Ping“…Artesunate (ART) is a semi-synthetic derivative of artemisinin used in the treatment of patients with malaria, which has also been reported to have immunoregulatory, anticancer and anti-inflammatory properties. …”
Publicado 2019
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28626“…It was found that zoonoses such as leptospirosis, brucellosis, Q fever and rickettsiosis among others are frequently under/misdiagnosed in febrile patients seeking treatment at healthcare centres, leading to overdiagnoses of more familiar febrile conditions such as malaria and typhoid fever. The interactions at the human–animal interface contribute substantially to zoonotic infections. …”
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28627por Gilson, Paul R., Kumarasingha, Rasika, Thompson, Jennifer, Zhang, Xinxin, Penington, Jocelyn Sietsma, Kalhor, Robabeh, Bullen, Hayley E., Lehane, Adele M., Dans, Madeline G., de Koning-Ward, Tania F., Holien, Jessica K., Soares da Costa, Tatiana P., Hulett, Mark D., Buskes, Melissa J., Crabb, Brendan S., Kirk, Kiaran, Papenfuss, Anthony T., Cowman, Alan F., Abbott, Belinda M.“…Our lead compound MB14 achieved modest inhibition of the growth in vitro of the human malaria parasite, Plasmodium falciparum. To identify its biological target we selected for parasites resistant to MB14. …”
Publicado 2019
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28628por Herzog, Sereina Annik, Leikauf, Gudrun, Jakse, Heidelinde, Siebenhofer, Andrea, Haeusler, Martin, Berghold, Andrea“…However, in other countries where a high prevalence of anemia is common due to risk factors such as malaria and HIV, early screening in pregnancy might be very important.…”
Publicado 2019
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28629por Chua, Tock H., Manin, Benny O., Vythilingam, Indra, Fornace, Kimberly, Drakeley, Chris J.“…PCR assay showed that 1.61% of the tested An. balabacensis were positive for malaria parasites, most of which were caught in oil palm estates and infected with one to two Plasmodium species. …”
Publicado 2019
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28630por Sajadpour, Zahra, Amini-Farsani, Zeinab, Motovali-Bashi, Majid, Yadollahi, Mitra, Yadollahi, Farrokh“…High linkage of a mutation with specific haplotype is consistent with the hypothesis that chromosomes carrying beta-thalassemia mutations experienced positive selection pressure, probably because of the protection against malaria experienced by beta-thalassemia carriers.…”
Publicado 2019
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28631Identification of adjuvants for clinical trials performed with Plasmodium falciparum AMA1 in rabbits“…Antibody levels (humoral responses) and functional activity of the antibodies induced against malaria vaccine candidate AMA1 were evaluated. Thus, in this study the ideal adjuvant is expected to induce high functional antibody levels, a long-lived response, and a broad cross-strain activity. …”
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28632por Ademola, Adebowale D, Asinobi, Adanze O, Ekpe-Adewuyi, Esther, Ayede, Adejumoke I, Ajayi, Samuel O, Raji, Yemi R, Salako, Babatunde L, James, Matthew, Zappitelli, Michael, Samuel, Susan M“…The underlying diagnoses in patients with AKI were sepsis (33.0%), malaria (12.5%) and primary renal disorders (13.4%). …”
Publicado 2018
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28633por Smith, Katherine A., Setlhare, Segolame, DeCaen, Allan, Donoghue, Aaron, Mensinger, Janell L., Zhang, Bingqing, Snow, Brennan, Zambo, Dikai, Ndlovu, Kagiso, Littman-Quinn, Ryan, Bhanji, Farhan, Meaney, Peter A.“…BACKGROUND: Serious childhood illnesses (SCI), defined as severe pneumonia, severe dehydration, sepsis, and severe malaria, remain major contributors to amenable child mortality worldwide. …”
Publicado 2019
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28634“…BACKGROUND: Drug resistance to malaria is still a problem in various regions, and there have even been developments in resistance to the ACTs (artemisinin-based combination therapies) as standard antimalarial drugs included to artemisinin’s partner drugs. …”
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28635por Ackert, Jessica, Mohamed, Khadeeja, Slakter, Jason S., El-Harazi, Sherif, Berni, Alessandro, Gevorkyan, Hakop, Hardaker, Elizabeth, Hussaini, Azra, Jones, Siôn W., Koh, Gavin C. K. W., Patel, Jyoti, Rasmussen, Scott, Kelly, Deborah S., Barañano, David E., Thompson, John T., Warren, Keith A., Sergott, Robert C., Tonkyn, John, Wolstenholme, Allen, Coleman, Hanna, Yuan, Alex, Duparc, Stephan, Green, Justin A.“…INTRODUCTION: Tafenoquine has been recently registered for the prevention of relapse in Plasmodium vivax malaria. OBJECTIVE: This study assessed the pharmacodynamic effects of 300-mg single-dose tafenoquine on the retina. …”
Publicado 2019
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28636por Li, Tony, Mbala-Kingebeni, Placide, Naccache, Samia N., Thézé, Julien, Bouquet, Jerome, Federman, Scot, Somasekar, Sneha, Yu, Guixia, Sanchez-San Martin, Claudia, Achari, Asmeeta, Schneider, Bradley S., Rimoin, Anne W., Rambaut, Andrew, Nsio, Justus, Mulembakani, Prime, Ahuka-Mundeke, Steve, Kapetshi, Jimmy, Pybus, Oliver G., Muyembe-Tamfum, Jean-Jacques, Chiu, Charles Y.“…Reads from Plasmodium falciparum (malaria) were detected in 21 patients, of which at least 9 (42.9%) were coinfected with EBOV. …”
Publicado 2019
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28637“…Potential areas of intervention arise for five different global health issues: malaria, non-communicable diseases, maternal and child health, HIV/AIDS, and tuberculosis. …”
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28638por Foguim, Francis Tsombeng, Robert, Marie Gladys, Gueye, Mamadou Wagué, Gendrot, Mathieu, Diawara, Silman, Mosnier, Joel, Amalvict, Rémy, Benoit, Nicolas, Bercion, Raymond, Fall, Bécaye, Madamet, Marylin, Pradines, Bruno“…The only significant differences in ex vivo susceptibility according to the K734M mutation were observed for pyronaridine for African isolates from imported malaria and for doxycycline for Senegalese parasites. …”
Publicado 2019
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28639por Pham, Thanh Binh, Hoang, Thi Hong Cam, Pham, Van Hai, Nguyen, Van Chuc, Nguyen, Thuy Van, Vu, Duc Chinh, Pham, Van Hoi, Bui, Huy“…Permethrin, 3-Phenoxybenzyl (1 RS)-cis,trans-3-(2,2-dichlorovinyl)- 2,2-dimethylcyclopropanecarboxylate, has a wide range of applications like insecticide, insect repellent and prevents mosquito-borne diseases, such as dengue fever and malaria in tropical areas. In this work, we develop a prominent monitoring method for the detection of permethrin pesticide using surface-enhanced Raman scattering (SERS) optical fibre substrates. …”
Publicado 2019
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28640por Pett, Helmi, Bradley, John, Okebe, Joseph, Dicko, Alassane, Tiono, Alfred B., Gonçalves, Bronner P., Stone, Will, Chen, Ingrid, Lanke, Kjerstin, Neuvonen, Mikko, Mustaniemi, Anna-Liina, Eziefula, Alice C., Gosling, Roly, D’Alessandro, Umberto, Drakeley, Chris, Niemi, Mikko, Bousema, Teun“…Genetic variation in CYP2D6, the gene producing the drug-metabolizing enzyme cytochrome P450 2D6 (CYP2D6), influences plasma concentrations of PQ and its metabolites and is associated with PQ treatment failure in Plasmodium vivax malaria. Using blood and saliva samples of varying quantity and quality from 8 clinical trials across Africa (n = 1,076), we were able to genotype CYP2D6 for 774 samples (72%). …”
Publicado 2019
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